Articles published on Intervention research
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- New
- Research Article
- 10.1177/21925682251407983
- Dec 8, 2025
- Global spine journal
- Sathish Muthu + 6 more
Study DesignUmbrella systematic review.ObjectiveTo qualitatively synthesise systematic reviews evaluating the prevalence, correlates, and outcomes of mental illnesses in individuals with traumatic spinal cord injury (tSCI).MethodsSystematic reviews reporting on depression, anxiety, post-traumatic stress disorder (PTSD), substance use disorders (SUD), cognitive impairment, and related psychological outcomes in tSCI populations were identified and synthesized as per PRISMA guidelines. Data on prevalence, risk factors, assessment tools, and interventions were extracted. Methodological quality was appraised using AMSTAR 2, and primary study overlap was assessed.ResultsTwenty systematic reviews published between 2005 and 2025 were included. Depression was the most frequently studied condition (n = 16), followed by anxiety (n = 10), PTSD (n = 6), and SUD (n = 4), with several reviews addressing multiple conditions. Primary study sample sizes ranged from 3152 to over 50000 participants, with wide variation in injury characteristics, study design, and outcome measures. Pooled prevalence estimates indicated a substantial burden: depression affected up to 43% of community-dwelling individuals, anxiety symptoms around 27%, PTSD up to 62%, and hazardous alcohol use ≥50% in some cohorts. Common risk factors included pain, injury severity, incomplete injury, low social support, maladaptive coping, and co-occurring psychological symptoms. Evidence for effective interventions was limited, and few studies used standardised, validated tools across settings.ConclusionsMental health conditions are highly prevalent in the tSCI population, yet intervention research remains limited. Standardised assessment, longitudinal designs, and targeted, evidence-based interventions are urgently needed to address this critical but under-recognised aspect of tSCI care.
- New
- Research Article
- 10.1186/s40900-025-00825-w
- Dec 5, 2025
- Research involvement and engagement
- Lauren Quetsch + 3 more
Parent-Child Interaction Therapy (PCIT) has been effectively implemented for autistic youth and their families who need help reducing disruptive behaviors, promoting language development, and enhancing the parent-child relationship. However, like most autism-based interventions, the PCIT protocol was originally adapted for (rather than with or by) the autism community. A new wave of intervention research calls for input from autism advocates throughout each phase of the research process. The present study signifies the first step in the development and implementation of a pilot PCIT program with autistic youth and their families (i.e., PCIT-Autism). Academic researchers collaborated alongside an Autism Community Advisory Board (CAB) comprised of autistic adults (N = 10) and caregivers of autistic youth (N = 14) to understand the current state of therapeutic services and their values for the development of an intervention to address autistic youth aggressive behaviors, when present. Five primary themes were generated from qualitative interviews with the Autism CAB related to psychological interventions: (1) Barriers to Accessibility, (2) Effectiveness, (3) Therapist Competence, (4) Topics, and (5) Format. Recommendations from the Autism CAB encouraged a hybrid (in-person, group-based + individualized telehealth), time-limited PCIT model which incorporated autism-affirming psychoeducation and practice, childcare, as well as opportunities for community-building.
- New
- Research Article
- 10.1111/add.70253
- Dec 4, 2025
- Addiction (Abingdon, England)
- Brendan Clifford + 9 more
This study sought to validate a community-acceptable Substance Use & Sex Index (SUSI) for use in substance use intervention research. SUSI aims to measure behaviours associated with the transmission of blood-borne viruses (BBV) and sexually transmitted infections (STI) among people who use substances and incorporate contemporary sexual and drug practices. Validation of a self-administered online behavioural questionnaire. An Australian anonymous online questionnaire advertised through health services and social media resulted in 289 respondents with a mean age 35 years (standard deviation [SD] 10.9years). A 26-item scale assessing BBV- and STI-associated behaviours based on previous piloting and expert review was assessed for scale structure using exploratory and confirmatory factor analytic approaches. Item Response Theory (IRT) analyses were applied in decisions to retain and categorise items. Item weightings were defined following expert consensus informed by local BBV, STI and HIV epidemiological profiles. Test-retest reliability was examined on a subsample (n = 98) over three to five days. Criterion validity of the new SUSI-2 scale was examined in comparison to the HIV Risk-taking Behaviour subscale of the Opiate Treatment Index (OTI-HRBS). Factor analysis identified a two-factor model ("sex"; "drugs with sex"), with moderate magnitude correlation (r = 0.38; 95% confidence interval [CI] 0.19-0.54) between factors and acceptable model fit (p = 0.061). IRT discrimination was statistically significant for all items (p < 0.05). Kappa values for test-retest reliability (n = 98 subsample) ranged from 0.66 to 1.00 with high agreement (all above 87%). Free text responses indicated the questionnaire items were acceptable to respondents, with minimal suggestion for improvements. There was a statistically significant positive correlation between the SUSI-2 and OTI-HRBS sex subscales (weighted r = 0.63, p < 0.001) and between the SUSI-2 sex with drugs and OTI-HRBS drug subscale (weighted r = 0.21, p < 0.01). Four additional items were retained to reflect local other BBV and STI transmission risk. The Substance Use & Sex Index 2 (SUSI-2) appears to be a valid and acceptable two-factor brief scale for the measurement of behaviours associated with blood-borne viruses and sexually transmitted infections for use in substance use interventional research.
- New
- Research Article
- 10.3389/fpsyg.2025.1589786
- Dec 4, 2025
- Frontiers in Psychology
- Shanshan Wang + 1 more
Introduction Psychological resilience is crucial for adolescent athletes facing competitive pressures, yet effective interventions remain understudied. This study examined the associations between mindfulness training and psychological resilience development in adolescent athletes. Methods A randomized controlled trial was conducted with 60 adolescent athletes (aged 14-18 years) from a provincial sports school in China. Participants were randomly assigned to an experimental group ( n = 30) receiving an 8-week mindfulness training program (90 minutes weekly) or a control group ( n = 30) maintaining regular training routines. Psychological resilience was assessed using the Connor-Davidson Resilience Scale at baseline, post-intervention, and 3-month follow-up. Potential moderating effects of gender and training experience were analyzed. Results The experimental group demonstrated significant improvements in total resilience scores from pre-intervention ( M = 62.47, SD = 10.21) to post-intervention ( M = 75.83, SD = 9.56, p &lt; 0.001, d = 1.35) and follow-up ( M = 77.90, SD = 9.14, p &lt; 0.001, d = 1.58), while the control group showed no significant changes. Improvements were observed across all resilience dimensions: personal competence, trust in instincts, positive acceptance of change, and control (all p &lt; 0.001). Neither gender nor training experience significantly moderated intervention effects. Discussion These findings provide empirical support for associations between mindfulness training and enhanced psychological resilience in adolescent athletes, with sustained effects at 3-month follow-up. The intervention’s effectiveness across gender and experience levels suggests broad applicability for mental health promotion in youth sports programs. Future research should examine causal mechanisms and long-term sustainability with larger, more diverse samples.
- New
- Research Article
- 10.1007/s41465-025-00338-0
- Dec 4, 2025
- Journal of Cognitive Enhancement
- Laura M Rosok + 6 more
Abstract Carotenoids, antioxidant plant pigments that accumulate in human tissues (e.g., brain, eyes, skin), may positively impact cardiovascular health, vision, and cognition. Skin carotenoids, reflecting total carotenoid intake, are understudied in child development. This research aimed to examine toddlers’ sensory, cognitive, language, and motor development over 12 months and their associations with skin carotenoids. Toddlers (12-18mo at baseline) participated in a 12mo cohort study: baseline ( n = 51), midpoint (18-24mo, n = 46), final assessment (24-30mo, n = 41; 80% completed all timepoints). Skin carotenoids were measured using reflection spectroscopy (Veggie Meter™). Cognitive, language, and motor skills were measured via Bayley Scale of Infant and Toddler Development IV Screening Test (BSID-IV). Mismatch negativity (MMN) and visual evoked potentials (VEPs) were elicited with auditory oddball and pattern reversal tasks, respectively, using electroencephalography. Repeated measures ANOVAs indicated no time effects for skin carotenoids, MMN, or VEPs. Effects were found for BSID-IV cognition, language, and motor skills (all p’s < 0.01). Regressions revealed that baseline skin carotenoids predicted increased gains in cognition from baseline to final timepoint (β = 0.35, p = 0.057), increased gains in fine motor skills from baseline to final timepoint (β = 0.46, p = 0.01) and baseline to midpoint (β = 0.41, p = 0.01), and increased gains in receptive communication from midpoint to final timepoint (β = 0.44, p = 0.01). Baseline skin carotenoids were not related to changes in VEP or MMN outcomes. These findings suggest that skin carotenoids may be linked to cognitive, language, and motor development in toddlers. Interventional research is needed to determine causal effects of carotenoid intake on infant and toddler development.
- New
- Research Article
- 10.5014/ajot.2025.051354
- Dec 4, 2025
- The American journal of occupational therapy : official publication of the American Occupational Therapy Association
- Brittany M St John + 4 more
Feeding is a multifaceted process that is frequently disrupted across pediatric populations, in particular among children with medical, developmental, or behavioral challenges. Occupational therapy practitioners possess unique expertise in providing comprehensive evaluations and interventions for feeding and eating skills, child regulation and behavior, mealtime routines, and family-centered goals during this essential activity of daily living. This State of the Science review synthesizes the current state of evaluation, intervention, and policy related to pediatric feeding within occupational therapy; specifically, we identify opportunities for expanded assessment development, intervention research, clinical research partnerships, and policy advocacy. We emphasize the importance of occupational therapy practitioners being part of multidisciplinary teams, consistently being recognized as qualified providers of feeding services, and being reimbursed for service provision across the United States related to pediatric feeding.
- New
- Research Article
- 10.56238/levv16n55-017
- Dec 4, 2025
- LUMEN ET VIRTUS
- Luciano Custódio Dos Santos Lima + 7 more
Introduction: Adolescent pregnancy represents a complex public health challenge associated with biological vulnerability, socioeconomic disadvantage, and increased susceptibility to psychological distress. Early pregnancy can disrupt neurodevelopmental trajectories, intensify emotional instability, and heighten exposure to adverse childhood experiences, all of which may shape long-term maternal mental health. Objective: The main objective of this systematic review was to evaluate the impact of adolescent pregnancy on maternal psychological development and the onset or worsening of mental disorders. Secondary objectives included assessing associations with depression, anxiety, trauma-related symptoms, parenting stress, and long-term psychiatric outcomes. Methods: A systematic search was conducted in PubMed, Scopus, Web of Science, Cochrane Library, LILACS, ClinicalTrials.gov, and ICTRP. Eligible studies included observational or interventional research evaluating mental health outcomes in pregnant adolescents or adolescent mothers. Inclusion criteria comprised studies published in the last five years, with expansion to ten years if fewer than ten eligible articles were available. Human studies were prioritized; animal and in vitro studies were considered only for mechanistic insights. Data extraction followed PRISMA guidelines, and risk of bias was assessed through RoB 2, ROBINS-I, and QUADAS-2, with certainty of evidence evaluated using GRADE. Results and Discussion: A total of 18 studies were included in the final review. The evidence consistently showed heightened rates of depressive symptoms, anxiety disorders, trauma exposure, impaired emotional regulation, and intergenerational psychosocial stress among adolescent mothers. Neurodevelopmental immaturity, socioeconomic adversity, and limited access to support services were recurrent mediators across studies. Conclusion: Adolescent pregnancy is strongly associated with increased vulnerability to mental health disorders and impaired psychological development. The findings highlight the need for integrated screening, targeted psychosocial interventions, and multidisciplinary follow-up strategies. Improved mental health support during pregnancy and postpartum may mitigate long-term psychiatric consequences in this high-risk population.
- New
- Research Article
- 10.1186/s12910-025-01348-5
- Dec 2, 2025
- BMC medical ethics
- Christine Bernardi + 8 more
According to legal and ethical obligations, patients must be thoroughly informed about the trial in which they could enrol, requiring them to consider and digest a significant amount of complex information. Many cancer patients feel overwhelmed which hinders their ability to make informed decision regarding their care. There is a need for further evidence-based strategies on how to improve both physician-patient-communication and informed consent (IC) documents in this area. We explored the views of experts from various disciplines on communication in IC processes in oncology. Seventeen semi-structured interviews with multidisciplinary experts were conducted and analysed using framework analysis. Several experts stated that IC documents have become highly legalistic, often prioritizing the interests of sponsors and further institutions involved over patient understanding. IC conversations are considered essential, as many patients do not thoroughly read IC documents. Conducting an unbiased IC conversation in an understandable manner may be challenging for physicians because they often have vested interests in recruiting patients for trials. Introducing evidence-based checklists for IC conversations and involving nursing staff may assist in addressing practical issues patients may have, reduce anxiety, and increase consent rates. Strategies to improve IC documents include reducing potentially irrelevant information (e.g., on contraception), improving the adaptation of international consent forms to local settings and incorporating graphical abstracts and study flowcharts to offer brief and visually engaging summaries. Additionally, fostering open dialogue and involvement of all relevant stakeholders (including patient representatives from various sociodemographic backgrounds) in designing IC documents may enhance IC processes. Many experts expressed the need for further research on the needs of different target groups, such as individuals with a migrant background or visual or other impairments. There is a significant gap between legal and ethical obligations related to IC and patients not being able to understand the abundance of unfamiliar, complex information provided to them. Evidence-based IC checklists, involving nursing staff and improved written IC materials may help improve communication in this area. Further interventional research is required to IC processes in oncology with the aim to provide optimal, patient-centred care.
- New
- Research Article
- 10.1038/s41597-025-06337-2
- Dec 2, 2025
- Scientific data
- Jian Guo + 7 more
Prototheca, one of the foremost causative agents responsible for opportunistic infections in both humans and animals. Despite the availability of several Prototheca genomes, the genomes of Prototheca bovis and Prototheca ciferrii have remained unsequenced. In this study, we report two high-quality genome assemblies for P. bovis strain SH08 and P. ciferrii strain SH13, representing two distinct species of the genus Prototheca. The final assembled genome sizes were 30.6 Mb for P. bovis SH08 and 32.7 Mb for P. ciferrii SH13, with contig N50 values of 1.19 Mb and 1.78 Mb, respectively. The repetitive sequences were identified in 14.79% and 14.24% of the assembled genomes, respectively. A total of 5,141 protein-coding genes were predicted for P. bovis SH08, while P. ciferrii SH13 contained 4,986 protein-coding genes. Functional annotation identified 97.28% and 99.16% of the genes in the genomes, respectively. These two novel high-quality genome assemblies represent valuable resources for advancing research in evolutionary biology, comparative genomics, pathogenicity assessment, diagnostic strategies, and therapeutic interventions in protothecosis.
- New
- Research Article
- 10.1186/s40814-025-01741-2
- Dec 2, 2025
- Pilot and feasibility studies
- Mark W Bruner + 8 more
Together For Us (T4Us) is a newly developed and evidence-informed social identity intervention for youth sport. Drawing on theoretical underpinnings of social identity theory and previous shared leadership intervention research in sport, T4Us leverages athlete leaders to foster a shared sense of social identity within the team. The purpose of this study was to conduct an initial feasibility study (Study 1) and a proof-of-concept evaluation (Study 2) to determine whether T4Us enhanced social identity and assessed the intervention implementation. In Study 1, five competitive youth ice hockey teams (mean age = 13.0years) completed T4Us at midseason. Overall, athlete leaders (n = 19) and coaches (n = 4) expressed support for the acceptability and feasibility of the initial T4Us workshop in a youth sport setting, including the creation of a unique team "trademark" and the shared leadership mapping exercise. Participants also recommended possible improvements to T4Us (e.g., intervention timing and follow-up booster sessions to reinforce content). In Study 2, a total of 14 competitive youth soccer teams (mean age = 14.7years) completed the revised T4Us at midseason. Descriptive results highlight that athletes' perceptions of social identity were higher at post-intervention in comparison with pre-intervention. Post-intervention implementation evaluation results revealed that the teams used the game plan to support the team trademark, and athlete leaders and coaches encouraged team members to act according to the team game plan (scores > 5 on a 7-point scale). Interviews with athlete leaders described the different ways in which T4Us enhanced social identity within the team. Overall, the initial feasibility evidence and the proof-of-concept evaluation support the further development of T4Us, including a randomized-controlled T4Us protocol.
- New
- Research Article
- 10.1016/j.jsp.2025.101505
- Dec 1, 2025
- Journal of School Psychology
- Keith C Herman + 2 more
Conceptual and methodological advances for understanding contextual, identity, and cultural effects in intervention research: The contextually informed research model
- New
- Research Article
- 10.1016/j.ridd.2025.105141
- Dec 1, 2025
- Research in developmental disabilities
- Hesna Gül + 4 more
Psychometric validation of the Barkley SCT (sluggish cognitive tempo) scale in Turkish adolescents: Assessing SCT in a clinically referred, culturally distinct population.
- New
- Research Article
- 10.1016/j.jvir.2025.09.002
- Dec 1, 2025
- Journal of vascular and interventional radiology : JVIR
- Sheridan L Reed + 7 more
The Woodchuck Hepatitis Virus Model of Hepatocellular Carcinoma for Interventional Radiology Research.
- New
- Research Article
- 10.1016/j.rmal.2025.100231
- Dec 1, 2025
- Research Methods in Applied Linguistics
- Man Ho Ivy Wong
A Bayesian approach to small samples: Mixed-effects modeling in L2 interventional research
- New
- Research Article
- 10.1016/j.metip.2025.100208
- Dec 1, 2025
- Methods in Psychology
- Rebecca Zarate + 5 more
Arts-mix: A pragmatist approach and framework for researcher-practitioners in mixed –methods and arts -based intervention research
- New
- Research Article
- 10.1016/j.invent.2025.100896
- Dec 1, 2025
- Internet Interventions
- Milon H.M Van Vliet + 6 more
A practical step-by-step approach for patient and public involvement in eHealth intervention research: Lessons learned from three case projects
- New
- Research Article
- 10.1016/j.ridd.2025.105169
- Dec 1, 2025
- Research in developmental disabilities
- Yu Zhang + 1 more
The evolving landscape: A bibliometric and visual analysis of language interventions research for children with ASD.
- New
- Research Article
- 10.1093/eurpub/ckaf180.052
- Dec 1, 2025
- European Journal of Public Health
- Kerrie Stevenson + 7 more
Abstract WKS 43: Promoting equity in migrant maternity care across Europe: How to actively involve migrant women in the design and implementation of interventions?, B307 (FCSH), September 5, 2025, 11:30 - 12:30 Rationales and Purpose Migrant women across the European region face persistent barriers to equitable maternity care, including exclusion from service design, language barriers, racism, and a lack of culturally responsive care. These inequities can contribute to poorer maternal and infant outcomes. This workshop aims to explore practical, effective, and sustainable methods for meaningfully involving migrant women in the co-design and implementation of maternity care interventions across the European region. It seeks to challenge existing research practices, encourage more inclusive, participatory approaches, and promote responsiveness in maternal health care services. Methods/Process of Workshop Using a roundtable format, this 60-minute session will be co-facilitated by a migrant woman with lived experience and an academic researcher. Five discussants will present brief case examples, including intervention research from the UK, Germany, and Denmark, alongside findings from a systematic review and qualitative study. A ‘Creative Thinking’ framework will guide participant engagement through mind mapping, live polling, and facilitated discussion to stimulate new ideas and capture diverse perspectives. Projected Learning Outcomes Participants will:
- New
- Research Article
- 10.4148/2161-4148.1126
- Dec 1, 2025
- International Journal of School Social Work
- Christina L Helfrick + 1 more
Getting Started: A Case for Intervention Research by School Social Workers
- New
- Research Article
- 10.47061/jasc.v5i2.10308
- Nov 30, 2025
- Journal of Awareness-Based Systems Change
- Lorenn Ruster
Academic research often privileges written language in both production and dissemination of knowledge. However, language exists alongside visual and material artifacts in the definition, sensemaking, transportation, and stabilization of organizations (Boxenbaum et al., 2018). In contrast, a focus on language is not as prominent in the realm of fashion, where visuals, aesthetics, and materiality are core (Castaldo Lundén, 2020; Jenß & Hofmann, 2019; Julier, 2006; Pecorari, 2021). This paper demonstrates how an appropriation of a commonly used visual artifact in fashion—the lookbook—can promote the surfacing, sensemaking, and co-creation of new organizational realities. The cybernetic lookbook compiles a series of visual representations of the organization, created through cybernetic diagramming practices—diagrams that reflect feedback loops, scales, thresholds, leverage points, and cybernetic awareness. These visual representations emerged in the context of intervention research with three organizations—two early-stage startups and one responsible technology ecosystem-enabler. Reflections on the process suggest that cybernetic diagramming afforded three types of convening spaces—conversation spaces, co-production spaces, and reflection spaces—prompting new shared understanding about the products being built, new product innovation ideas, and potential new ways to communicate organizational stories as well as that of the research itself. It is hoped that this contribution may open novel avenues for visual methods experimentation for organizational understanding.