International Efforts Research Articles

Comparative Study of Keras CNNs for Tuberculosis Detection from Chest X-rays

As a major global health burden, tuberculosis (TB) requires prompt and accurate diagnostic solutions. The effectiveness of Convolutional Neural Networks (CNNs) for TB prediction from chest X-ray images is investigated in this work using a variety of Keras applications. We compare the accuracy, efficiency, and computational resource usage of the VGG16, ResNet50, and EfficientNetV2B2 architectures. By means of comprehensive testing and analysis on a wide range of datasets, we determine the applicability of every model for tuberculosis identification. The findings show that EfficientNetV2B2 is the most promising architecture, achieving remarkable accuracy (99.5%) with enhanced computational efficiency, while VGG16 and ResNet50 show competitive performance. These results highlight how deep learning-based methods have the potential to transform tuberculosis diagnosis by providing doctors with a trustworthy and usable instrument for early detection and treatment. Our research has implications for improving healthcare outcomes and bolstering international efforts to fight tuberculosis. Keywords—EfficientNet, CNN, VGG16,Keras, Accuracy

Equal allocation, demand priority or negotiated allocation? How to allocate water resources in the Tigris and Euphrates River Basin efficiently

The Tigris and Euphrates River Basin is an important water supply, but it suffers from water scarcity. It is necessary to carry out reasonable allocation of water resources in this region. Since water resources issues in this region are of multinational interest, international cooperative distribution efforts are needed. Common water resources allocation modes include equal allocation, demand priority or negotiation allocation. In order to derive the applicable range of various water resources allocation modes, this article constructs three differential game models and compares and analyzes the equilibrium results obtained by the models. Finally, the study shows that when the cost of developing water resources is small and the revenue obtained from developing water resources is large, the water-scarce region can obtain the maximum benefit by adopting the demand priority mode. Otherwise, the water-scarce region can obtain the maximum benefit by adopting the negotiation allocation mode. This study can inform the allocation, strategic interaction and cooperation of dynamic water resources in the two river basins.

Longest recorded migration of a silky shark (Carcharhinus falciformis) reveals extensive use of international waters of the Tropical Eastern Pacific.

Despite being a heavily fished species, little is known about the movements of silky sharks (Carcharhinus falciformis). In this study, we report the longest (in duration and distance traveled) and most spatially extensive recorded migration for a silky shark. This shark, tagged with a fin-mount satellite transmitter at the Galapagos Islands, traveled >27,666 km over 546 days, making two westerly migrations into international waters as far as 4755 km from the tagging location. These extensive movements in an area with high international fishing effort highlights the importance of understanding silky shark migrations to inform management practices.

Protecting Intellectual Property Rights in the Digital Age

This research paper discusses safeguarding intellectual property rights (IPR) amidst emerging technologies and cyber threats. In the digital age, safeguarding intellectual property rights (IPR) amidst emerging technologies and cyber threats necessitates a proactive and collaborative approach. This research paper explores the multifaceted challenges and opportunities surrounding IPR protection, focusing on the impacts of artificial intelligence, blockchain, 3D printing, and the Internet of Things. By analyzing legal responses, technological solutions, international cooperation efforts, and future trends, it equips stakeholders with insights to navigate this complex terrain effectively. The paper advocates for dynamic regulatory frameworks that balance innovation with risk management and societal interests, emphasizing cross-sector collaboration in policy development. It also highlights the importance of public awareness and education in empowering individuals to navigate emerging technology landscapes safely. Additionally, the paper addresses the historical background, types of IPR, contemporary issues, cyber security challenges, and collaboration between stakeholders. By implementing comprehensive strategies and fostering collaboration, organizations can uphold the integrity of intellectual property rights, incentivize innovation, and maintain a competitive edge in the digital landscape.

Radioactive Waste Management Challenges: Nigerian Case Study

Preceding the publication of the Nuclear Safety and Radiation Protection Act 19 of 1995 (Act) by the Justice Ministry in 1995 (Justice, 1995) and the establishment of the Nigerian Nuclear Regulatory Authority (NNRA) in 2001, radioactive sources had for decades been used for various practices in Nigeria (Ogharandukun, 2017). These early activities involving radioactive sources gave rise to some legacy radioactive waste. NNRA undertook some early actions soon after its inception to ensure the safe management of this legacy radioactive waste. These actions, amongst other outcomes, highlighted the inadequacies of the Nigerian radioactive waste management system. The approval of radiation safety and radioactive waste management regulations enabled the NNRA to enter into national and international cooperative efforts to search for, secure, and create a proper inventory of the radioactive waste in Nigeria and effectively handle and manage it. Implementing the waste management system further highlighted the need for the approval of a national policy on radioactive waste management and the management of disused radioactive sources.

Hungry Faces Beyond the Battlefield—Examining Global Food Security in the Context of the Russo-Ukrainian Conflict in a Low- to Middle-Income Population in West Bengal: A Mixed-Methods Study

The Russo-Ukrainian conflict has garnered global attention for its geopolitical ramifications, but its impact on food security in regions far from the battlefield remains underexplored. This qualitative study delves into the repercussions of the conflict on food security within a low- to middle-income population in Murshidabad, West Bengal, India. Employing semi-structured interviews and Likert scale assessments, we sought to understand the nuanced experiences and perceptions of individuals affected by the conflict-induced disruptions in global food markets. Our findings reveal profound challenges to food security, with 68% of respondents reporting increased difficulty in accessing affordable and nutritious food since the onset of the conflict. Moreover, 52% expressed heightened concerns about future food availability and affordability, indicating a pervasive sense of uncertainty and anxiety. Importantly, qualitative analysis uncovered multifaceted impacts, including disruptions in supply chains, inflationary pressures, and shifts in dietary patterns towards less nutritious options. This study highlights the interconnectedness of geopolitical conflicts and local food security, shedding light on the often-overlooked consequences faced by vulnerable populations thousands of miles away from the conflict zone. Such insights underscore the imperative for coordinated international efforts to mitigate the adverse effects of conflicts on food security and safeguard the well-being of communities worldwide. These findings contribute to a growing body of literature on the complex interplay between global geopolitics and local livelihoods, urging policymakers to adopt holistic approaches to address the multifaceted challenges of food insecurity in conflict-affected regions and beyond.

The planetary protection strategy of Mars Sample Return’s Earth Return Orbiter mission

The Mars Sample Return campaign aims to use three flight missions and one ground element to safely bring rock cores, regolith and atmospheric samples from the surface of Mars to Earth to answer key questions about the geologic and climate history of Mars, including the potential for ancient life. Since its landing in Jezero Crater in 2021, the first mission, NASA’s Mars 2020, has collected a number of samples on the crater floor and on the delta using the Perseverance rover. Subsequent missions would recover the sealed sample tubes, launch them into Mars orbit, and transport them back to Earth. The ground element would be a high-containment facility that would isolate and protect the samples during initial sample characterization, which would include sample safety assessments and time-sensitive scientific investigations. These elements are currently in the planning and design stages of development, and represent an international effort of NASA, the European Space Agency (ESA), and many industry partners. The work presented here provides an overview of the planetary protection strategy of the third flight mission, the ESA-led Earth Return Orbiter, which hosts the NASA-provided Capture, Containment, and Return System. The orbiter would detect and capture the container with up to 30 sealed tubes previously put in Martian orbit, contain them in redundant containers to ensure that no potentially hazardous Mars particles are released, and return them to Earth through an entry vehicle. Both NASA and ESA policies comply with the United Nations’ Outer Space Treaty by planning to protect Earth’s biosphere from any potential adverse effects from material returned from solar system bodies beyond the Earth-Moon system. In the conduct of Mars Sample Return, the two agencies have mutually agreed to apply approaches consistent with their own planetary protection standards to the campaign elements they each provide.

Explanation and Elaboration with Examples for CLEAR (CLEAR-E3): an EuSoMII Radiomics Auditing Group Initiative

Overall quality of radiomics research has been reported as low in literature, which constitutes a major challenge to improve. Consistent, transparent, and accurate reporting is critical, which can be accomplished with systematic use of reporting guidelines. The CheckList for EvaluAtion of Radiomics research (CLEAR) was previously developed to assist authors in reporting their radiomic research and to assist reviewers in their evaluation. To take full advantage of CLEAR, further explanation and elaboration of each item, as well as literature examples, may be useful. The main goal of this work, Explanation and Elaboration with Examples for CLEAR (CLEAR-E3), is to improve CLEAR’s usability and dissemination. In this international collaborative effort, members of the European Society of Medical Imaging Informatics−Radiomics Auditing Group searched radiomics literature to identify representative reporting examples for each CLEAR item. At least two examples, demonstrating optimal reporting, were presented for each item. All examples were selected from open-access articles, allowing users to easily consult the corresponding full-text articles. In addition to these, each CLEAR item’s explanation was further expanded and elaborated. For easier access, the resulting document is available at https://radiomic.github.io/CLEAR-E3/. As a complementary effort to CLEAR, we anticipate that this initiative will assist authors in reporting their radiomics research with greater ease and transparency, as well as editors and reviewers in reviewing manuscripts.Relevance statement Along with the original CLEAR checklist, CLEAR-E3 is expected to provide a more in-depth understanding of the CLEAR items, as well as concrete examples for reporting and evaluating radiomic research.Key points• As a complementary effort to CLEAR, this international collaborative effort aims to assist authors in reporting their radiomics research, as well as editors and reviewers in reviewing radiomics manuscripts.• Based on positive examples from the literature selected by the EuSoMII Radiomics Auditing Group, each CLEAR item explanation was further elaborated in CLEAR-E3.• The resulting explanation and elaboration document with examples can be accessed at https://radiomic.github.io/CLEAR-E3/.Graphical

Modern Illegal Drug Business in Ukraine: Multidisciplinary Study of the System of Prevention and Countermeasures Against the Legalization of Income (Money Laundering) Obtained by Criminal Means

Established that the modern illegal drug trade is an integral part of transnational organized crime, involving the laundering of proceeds obtained through criminal activities. A comprehensive multidisciplinary study was conducted to evaluate the effectiveness of Ukraine's efforts to combat the contemporary drug trade and to analyze the international system for preventing and countering the legalization of illicit income (money laundering). This study confirmed the connection between transnational organized crime and the laundering of money derived from the illegal trafficking of banned psychoactive substances. The research emphasized the critical need to enhance the criminal and legal frameworks, improve medical and pharmaceutical support, and expand social and economic assistance. By examining the global experience in combating organized crime and drug-related offenses, the study provided valuable insights into effective strategies. Particular attention was given to forensic pharmaceutical practices related to the detection of prohibited psychoactive substances and the legalization of income from their illicit trade. To address these challenges, the study recommends increasing the criminal liability for members of organized drug trafficking gangs and suggests specific amendments to articles 115, 305, and 307 of the Ukrainian Criminal Code. Furthermore, a detailed analysis of the European Union’s roadmap and international cooperation efforts in combating the illegal circulation of prohibited psychoactive substances and the laundering of illegal profits was conducted. Normative initiatives aimed at amending Article 209 of the Ukrainian Criminal Code were developed and proposed. The study indicated the importance of implementing the EU Roadmap measures in Ukraine to foster cooperation among various private and public institutions. This collaborative approach aims to coordinate joint actions, conduct research, and organize conferences and training sessions based on the EMCDDA European prevention program and UN initiatives. The study underscores the relevance, timeliness, and practical significance of engaging the international community, including scientists, medical professionals, pharmacists, students, the public, legal experts, law enforcement, and government authorities. Through this multidisciplinary approach, the study seeks to promote a more effective and coordinated response to the challenges posed by the modern drug trade and its associated criminal activities.

Social media influence on COVID-19 vaccine perceptions among University students: a Malawi case study

IntroductionThe global fight against the COVID-19 pandemic relies significantly on vaccination. The collective international effort has been massive, but the pace of vaccination finds hindrance due to supply and vaccine hesitancy factors. Understanding public perceptions, especially through the lens of social media, is important. This study investigates the influence of social media on COVID-19 vaccine perceptions among university students in Malawi.MethodsThe study utilized a quantitative methodology and employed a cross-sectional study design to explore the relationship between social media dynamics and COVID-19 vaccine perceptions among 382 randomly sampled students at MUBAS. Data, collected by use of a Likert-scale questionnaire, was analyzed using IBM SPSS 20 for descriptive statistics and Pearson correlation tests.ResultsThe findings reveal crucial correlations. Specifically, trust in online vaccine information shows a positive correlation (r = 0.296, p < 0.01) with active engagement in social media discussions. Conversely, a negative correlation surfaces concerning individuals’ reactions to vaccine availability in Malawi (r = -0.026, p > 0.05). The demographic overview highlights the prevalence of the 16 to 30 age group, representing 92.9% of respondents.ConclusionsThe identified correlations emphasize the need for careful communication strategies tailored to combat misinformation and enhance vaccine acceptance among the younger demographic in Malawi. The positive correlation between trust in online vaccine information and social media engagement underscores digital platforms’ potential for disseminating accurate information. Conversely, the negative correlation with vaccine availability reactions suggest the presence of complex factors shaping public perceptions.

Internationalization moderating the relationship between investment and innovation in small businesses in Latin America

Objective: This paper's main objective was to examine the extent to which internationalization efforts moderate the relationship between investments in research and development (R&amp;D) and innovation outputs taken by small businesses, that is, small and medium-sized enterprises - SMEs. Methodology: The methodology used consisted of quantitative research with data from 10,621 SMEs, from 17 countries in Latin America. The present study involved factorial and regressive analysis as well. Main results: The results obtained led to the conclusion that internationalization efforts have a positive and statistically significant influence on innovation outputs, allowing SMEs in Latin American countries to increase their competitiveness through constructing or improving products, services, or processes. Theoretical contributions: At the end of the research, it was also concluded that R&amp;D investments positively influence innovation outputs and that companies that invest in R&amp;D and additionally employ internationalization efforts are more likely to present innovation. Relevance and originality: It was the first time that a study jointly and empirically evaluated the moderating effect of internationalization efforts on the relationship between investments in R&amp;D and innovation outputs, totaling a sample of 10,621 SMEs. Managerial and social contributions: This study also contributed to the knowledge of Latin America, therefore, it is expected that a greater understanding of the barriers to the development of SMEs will be achieved, through the advancement of internationalization efforts, investment in R&amp;D and innovation. In this way, the aim is to encourage academics and practitioners to search for solutions to break these barriers.

Multilingualism in Scientific Literature Communicated by Journals from the SciELO Brazil Collection

This article describes the internationalization of the Scientific Electronic Library Online (SciELO), an open-science programme aimed at the development of capacities and infrastructure in research communication. It manages open-access collections of preprints, articles, research data, books, and book chapters, with a focus on national collections of non-profit peer-reviewed journals published by research communities of academic institutions, scientific societies, and associations. Celebrating 25 years of regular operation, SciELO improves research communication through professionalization, internationalization and sustainability of the indexed journals, maximizing their visibility and impact. In Brazil, the internationalization efforts by SciELO are aligned with national research policies, especially the internationalization of graduate programmes. The SciELO Brazil collection of journals evolves by adopting English solely or with Portuguese to improve the contribution of multilingualism to performing research by subject field. This article covers two decades of scientific literature in SciELO Brazil from 2003 to 2022. During this time, articles written in English or simultaneously in Portuguese and English increased significantly, resulting in a corresponding rise in access and citations received. The progress of the internationalization of the journals in the SciELO Brazil collection through multilingualism has been challenging both operationally and programmatically.

A History of International Engagement in the Council for Exceptional Children Since 1980. Part 1: Organizational Components

Abstract Is the Council for Exceptional Children (CEC), arguably the largest professional organization in exceptional education in the world, international or not? What does it mean to be international? An integrative literature review of primary sources of CEC news articles, reports of initiatives and workgroups, and columns in CEC publications that provided records of the Council’s internationally related thinking and activities involving countries outside the United States and Canada was conducted to reconceptualize CEC’s international nature since 1980. In this article, we report the findings from these sources that provide evidence of international aspirations and activities at times for six organizational components of CEC—mission and vision, policy, units, committees, work groups, and membership. There were instances of international thinking and efforts in these components. Both are necessary for meaningful international engagement, as neither is sufficient on its own. Our results suggest, though, that each may have been wanting. Recommendations are provided on how CEC can increase its global engagement through these elements.

Aid and Governance

The relationship between aid and governance has been a topic of considerable discussion and debate within the international development community. Good governance and effective institutions have long been spotlighted by development partners as essential for economic development and aid effectiveness. With the adoption of the Sustainable Development Goals in 2015, they have been recognized globally also as development goals in themselves – framed, as set out in SDG 16, with attention to peace, access to justice, and ‘effective, accountable, and inclusive institutions’. Yet at the same time that aid has been seen to play a pivotal role in international efforts to support and incentivize better governance, long-voiced critiques have spotlighted how it also may have (unintentionally) negative impact on the same. Recent global trends and events further have served to focus attention on the role of aid, and the challenges faced by aid, in relation to governance and institution-building.

Crop yields fail to rise in smallholder farming systems in sub-Saharan Africa

Drawing on a harmonized longitudinal dataset covering more than 55,000 smallholder farms in six African countries, we analyze changes in crop productivity from 2008 to 2019. Because smallholder farmers represent a significant fraction of the world's poorest people, agricultural productivity in this context matters for poverty reduction and for the broader achievement of the UN Sustainable Development Goals. Our analysis measures productivity trends for nationally representative samples of smallholder crop farmers, using detailed data on agricultural inputs and outputs which we integrate with detailed data on local weather and environmental conditions. In spite of government commitments and international efforts to strengthen African agriculture, we find no evidence that smallholder crop productivity improved over this 12-y period. Our preferred statistical specification of total factor productivity (TFP) suggests an overall decline in productivity of -3.5% per year. Various other models we test also find declining productivity in the overall sample, and none of them finds productivity growth. However, the different countries in our sample experienced varying trends, with some instances of growth in some regions. The results suggest that major challenges remain for agricultural development in sub-Saharan Africa. They complement previous analyses that relied primarily on aggregate national statistics to measure agricultural productivity, rather than detailed microdata.

Co-creating with students to promote science of learning in higher education: An international pioneer collaborative effort for asynchronous teaching

Recent insights from Science of Learning (SoL) are informing instruction, training, and curriculum. Here, we present a project on promoting SoL-related content through co-creating online asynchronous learning resources. By building a 7-person cross-institution team, we strategically harnessed (1) student-faculty partnerships as a mechanism to promote training and professional development, (2) co-creation as a model to curricula development, (3) blended asynchronous learning as a modality for content delivery, and (4) internationalization as a strategy to embrace globalization. This co-creation of curricula project included three stages—literature review, design and production, and evaluation. The project evaluation deployed a mixed methods approach with 6 student evaluators across both participating institutions, who explored the effectiveness of the learning resources. In addition, student partners contributed reflective statements on their co-creation experience. This paper reports on the procedural pipeline to co-creation and the project evaluation, as well as on new insights emerging for curriculum development. We conclude that project's co-created learning resources may enhance effectiveness of instructional design and students’ learning experience. Further, we demonstrate that student partners acquire new knowledge and research, design and delivery skills, futureproofing their academic progression.

Fit-for-Purpose Ki-67 Immunohistochemistry Assays for Breast Cancer

New therapies are being developed for breast cancer, and in this process, some “old” biomarkers are reutilized and given a new purpose. It is not always recognized that by changing a biomarker’s intended use, a new biomarker assay is created. The Ki-67 biomarker is typically assessed by immunohistochemistry (IHC) to provide a proliferative index in breast cancer. Canadian laboratories assessed the analytical performance and diagnostic accuracy of their Ki-67 IHC laboratory-developed tests (LDTs) of relevance for the LDTs’ clinical utility.Canadian clinical IHC laboratories enrolled in the Canadian Biomarker Quality Assurance Pilot Run for Ki-67 in breast cancer by invitation. The Dako Ki-67 IHC pharmDx assay was employed as a study reference assay. The Dako central laboratory was the reference laboratory. Participants received unstained slides of breast cancer tissue microarrays with 32 cases and performed their in-house Ki-67 assays. The results were assessed using QuPath, an open-source software application for bioimage analysis. Positive percent agreement (PPA, sensitivity) and negative percent agreement (NPA, specificity) were calculated against the Dako Ki-67 IHC pharmDx assay for 5%, 10%, 20%, and 30% cutoffs.Overall, PPA and NPA varied depending on the selected cutoff; participants were more successful with 5% and 10%, than with 20% and 30% cutoffs. Only 4 of 16 laboratories had robust IHC protocols with acceptable PPA for all cutoffs. The lowest PPA for the 5% cutoff was 85%, for 10% was 63%, for 20% was 14%, and for 30% was 13%. The lowest NPA for the 5% cutoff was 50%, for 10% was 33%, for 20% was 50%, and for 30% was 57%.Despite many years of international efforts to standardize IHC testing for Ki-67 in breast cancer, our results indicate that Canadian clinical LDTs have a wide analytical sensitivity range and poor agreement for 20% and 30% cutoffs. The poor agreement was not due to the readout but rather due to IHC protocol conditions. International Ki-67 in Breast Cancer Working Group (IKWG) recommendations related to Ki-67 IHC standardization cannot take full effect without reliable fit-for-purpose reference materials that are required for the initial assay calibration, assay performance monitoring, and proficiency testing.

An Ethical Framework for Climate Intervention Research: What It Is and Why You Should Care

Climate change poses significant threats to ecosystems, human health, and global stability. Despite international efforts to reduce greenhouse gas emissions, the Earth&amp;rsquo;s climate continues to warm, leading to extreme weather events, rising sea levels, and other detrimental impacts. In response to this crisis, scientists have begun exploring various strategies to mitigate climate change through geoengineering, which involves deliberate interventions in the Earth&amp;rsquo;s climate system. This article provides an overview of climate geoengineering research, focusing on key techniques, challenges, and ethical considerations, including actions being taken by the American Geophysical Union (AGU), a nonprofit professional scientific society, to develop an ethical framework to help guide research in this important area. AGU also is driving global engagement on this topic, including with leaders and members of faith communities.

The Function of RNA Interference (RNAi) in Crop Enhancement- Mechanism and Applications: A Review

RNA interference (RNAi) is a conserved molecular mechanism that plays a critical role in post-transcriptional gene silencing across diverse organisms. This review delves into the role of RNAi in plant functional genomics and its applications in crop improvement, highlighting its mechanistic insights and practical implications. The overview starts with the fundamental finding of the mechanism of RNAi, following its journey from petunias to its ubiquitous presence in a wide range of species. The discovery of several kinds of regulatory non-coding small RNAs, including as phasiRNAs, miRNAs, and siRNAs, has broadened our knowledge of RNAi-mediated gene regulation beyond what is previously thought. These RNA types have an impact on gene expression through complex post-transcriptional and epigenetic mechanisms. RNA interference (RNAi) has become a potent tool for comprehending gene activities in the context of crop improvement. It has shown to be useful in determining the functions of genes for metabolic pathways, stress tolerance, and more. Furthermore, RNAi-based strategies have potential for sustainable agriculture and integrated pest management, supporting international efforts to ensure food security. The many uses of RNA interference (RNAi) are covered in this article, including improving crop nutrition, changing plant architecture, and increasing shelf life. The challenges and future prospects of RNAi technology are also explored. The worldwide geography of RNA interference research is emphasized, with notable contributions from North America, Europe, and China. In conclusion, RNA interference (RNAi) continues to be a flexible and essential tool in contemporary plant research, providing new pathways for understanding gene activities and enhancing crop characteristics. Its combination with other biotechnological techniques, such as gene editing, might influence how agriculture and sustainable food production develop in the future.

Safeguarding against cyber threats: legal measures for ensuring cybersecurity

The evolution of information technology has defined a new concept for society - cyberspace. Cyberspace is described as a channel for creating and disseminating various data types on the Internet. In addition to providing information, cyberspace contains several problems that require efforts, resources, and the introduction of legal measures. The relevance of the study on this issue is stipulated by the development of information technologies and the high risks that occasionally manifest themselves as cyberattacks. Cyberattacks cannot be limited or deterred, but they can be protected against. For this reason, one of the main priorities for the state nowadays is to protect the information sphere from cyberattacks and cyber threats, as well as to introduce adequate mechanisms to reduce these risks at the legal level. When studying the issue of cybersecurity, it is essential to emphasize how this type of security matters no less than national or internal security. As Ukraine moves closer to the EU, it is crucial to strengthen the facilitation of protection against cyberattacks. It is also essential to find effective methods and tools to not only preserve sensitive information but also to help restore lost resources quickly and efficiently. In addition, it is necessary to bring national legislation in line by adopting regulations that can be really useful in countering external threats. Ukraine is currently an active participant in international efforts to counter cybercrime. The country participates in various projects initiated by the EU and NATO, including strengthening security and defense sector protection and joint exercises of security and defense actors as part of collective defense measures. The proper level of cybersecurity in the country determines society's standard of living and development. For this reason, special attention should be paid not only to the means and methods of protection against cyber threats and attacks but also to the relevant legislative elaborations.