Innovative Development Path Research Articles

Современная инфраструктура инновационно-культурной среды


 The need for science to master the new reality inevitably involves a radical change of philosophical, methodological patterns and mechanisms of cognition. This poses a number of problems that are difficult to solve only on the basis of sound scientific methods. Required is also the use of new cognitive mechanisms, including psychological protection of man and his ability to influence the processing of the incoming information on the merits. Traditional scientific mechanisms are limited in their capabilities and therefore require an intuitive getting into the known and innovative thinking. Development of innovative thinking requires the society, which is radiating energy of creative environment, aimed at innovative transformations. Within this single concept formed a very important process, automatically pushing superconscious to the fore. The ratio of the rational and the intuitive turns a new paradigm of scientific knowledge in practice of creative noosphere, the sphere of synergy. The two systems can operate simultaneously in the operation of market institutions, providing a synergistic effect. The results of the analysis associated with the formation of innovation and cultural environment necessary for the formation and development of innovative processes in the countries and at the international level. It is noted that the combination of traditional culture and innovation and cultural environment should be assessed as the competitive advantages of the country. In the interests of achieving the unity of the individual, the people and the state play a positive role in adherence to the principles of national traditions of collectivism and catholicity.
 In the transition to the path of innovative development the main component affecting the internal and external transformation of society, according to the authors, is represented by perfectly formed innovation infrastructure in innovation-cultural environment. The innovative active person should be recognized as a priority. Progressive system, that takes into account the interests of the majority rather than a particular group, increases its positive potential. This is crucial, as without it cannot be implemented models of modernization of the real sector of the Russian economy and its integration into the modern international economy. The article examines the key issues of this economic development.

The path to innovative drug development of cancer vaccine: from discovery of tumor antigens to clinical trials

Tumor immunology has been advancing after the great discovery of tumor-specific antigen MAGE in 1991, and a number of tumor antigens have been reported to date. We have also found novel tumor antigens through various methodologies such as gene expression cloning, bioinformatics, reverse immunology, transcriptome analysis and peptidome analysis. Recently, we made a success of defining cancer stem cell-specific antigens. The fruits of our basic research have been applied to clinical trials of cancer vaccine. The long path and future perspectives of innovative immunotherapeutic drug development are described.

Изменение парадигмы исследований экономической безопасности региона

This paper shows the changes in theoretical and methodological approaches to the diagnosis of the economic security of the regions that have taken place over the last 20–25 years. This period covers a complex way, which Russia overcame since the beginning of perestroika, when the country faced two crises, surviving changing socio-economic structure and choosing the path of innovative development. The authors suggest that an assessment of the «health» of the regions in terms of economic security and the division into separate spheres is an effective methodological tool that allows not only ascertaining the state, but also looking into the future development. This paper, on the one hand, is a kind of report on the results of the Ural scientific school on the issues of economic security, on the other hand, it demonstrates the authors’ opinion (not always coinciding with other researchers') on this issue.

Системный подход к модернизации и инновационному развитию региона: стратегические цели

Russia must follow the path of modernisation and innovative development. The analysis conducted shows the absence of laws, strategies and uniform terminology regarding modernisation and innovations. The author examines the factors affecting the content of these terms, describes the system approach to modernisation and regional innovative development, develops regional methodology and identifies the strategic targets for modernisation and innovative development.

Russia-2050

This article deals with the contradiction between current Russian cultural tradition - orientation at survival of isolated individuals looking for solutions to present-day problems and lacking a clear vision of what the future will bring - and the necessity to switch Russia to the innovative development path based on transformation of the presently inflexible institutional system.

SUBSTANTIATION OF ELEMENTS AND STRUCTURE OF ORGANIZATIONAL AND ECONOMIC MECHANISM OF INTERNET MARKETING FOR DEVELOPING TOURISM ENTERPRISES ON INNOVATIVE PRINCIPLES

Perspective directions in strategizing the Internet marketing policy for innovative development of tourism enterprises are formed. A methodological approach has been developed and proposed, which allows to effectively and on an institutional basis combine opposite strategic vectors of activating Internet marketing of innovation: external vector (when a company focuses on innovation, related to trends in market demand and external need for innovation) and internal vector (when the path of innovative development and activity is determined by internal potential and financial resource capacity). Thus, the peculiarity of the author's approach is in the identification of organizational-managerial, information-technological, integrated, financial-investment, marketing, immanent, infrastructural, cluster and interactive spatial-network directions of innovative development with clear signs of synergy. The applied significance of the research is to determine the strategic concept and design a structure of the organizational and economic mechanism for improving Internet marketing of tourism enterprises on an innovative basis, as well as to substantiate the provisions of the organizational and economic mechanism of tourism development on an innovative basis. The scientific novelty of the research results is that the developed tools of policy of formation and implementation of organizational and economic mechanism of Internet marketing for the tourism enterprise development on innovative principles based on new tools and concepts of system and complexity of their combination, traditional substantiation of a set of proposals for the organization and control of innovation, the introduction of a number of economic incentives and motives for its internal and external actors. Such innovative principles allowed to substantiate the essential-typological and applied characteristics of functional and structural elements of the organizational-economic mechanism: institutional-legal base, administrative-functional apparatus, information-analytical block, scientific-technical support, financial-investment support, market-interface superstructure, intellectual-personnel component and logistics.