Initial Commitment Research Articles

Career Accomplishments of Public Health Service Alumni of the Uniformed Services University of the Health Sciences: Classes of 1980-2017.

The purpose of this study was to report on the career accomplishments of Public Health Service (PHS) alumni from the Uniformed Services University (USU) School of Medicine (SOM) in several professional areas such as specialty choice, board certification rates, leadership roles, academic achievements, deployments, and length of service. This study was conducted using the data obtained from the Long-Term Career Outcomes Study Alumni Survey. The cohort included all alumni who graduated from the SOM classes of 1980-2017. We analyzed the frequency distributions of the survey items of interest of the PHS alumni. Out of the 144 PHS alumni we reached, 39 responded, yielding a 27.1% response rate. 56.0% of PHS alumni entered primary care specialties and 97.0% were board certified in their first residency trained specialty. 30.6% of PHS alumni completed residency training in a military facility. 87.2% of PHS alumni have been in a leadership role since medical school, and 67.6% of PHS alumni currently hold a leadership role. 7.7% of PHS alumni have deployed for ≥30 days to a theater of combat operations. 66.7% and 71.8% of PHS alumni engaged in medical humanitarian and volunteering missions, respectively, and 75% of PHS alumni stayed in active duty longer than their initial commitment. 71.8% of PHS alumni were published in peer-reviewed journals and 17.6% were academically affiliated with USU. Our findings suggest that PHS alumni are likely to enter primary care specialties, engage in medical volunteering and humanitarian missions, frequently remain in uniform longer than their initial active duty commitment, and are affiliated with numerous universities and medical schools throughout their career. PHS alumni appear to be successfully meeting the mission set forth by the U.S. PHS.

Institutional Deficiencies of the Paris Agreement and China's Compliance Capacity: An Evaluation after US Withdrawal

The successful negotiation of the Paris Agreement, and its subsequent signing and adoption in 2016, marked a new landmark in global climate governance. However, the viability of the agreement was questioned particularly after the United States announced its withdrawal in 2017, pointing to certain institutional deficiencies in the overall agreement. The signing of the agreement would not have been possible without the initial joint commitment of both China and the United States, the world's two largest greenhouse gas emitters. Despite China's official claims of steadfast compliance with the agreement, the country's capacity to fulfil its commitment remains unclear. This study aims to first determine the constitutional deficiencies of the agreement that spurred America's withdrawal and the impacts. Second, it evaluates China's compliance capacity in the post-Paris Agreement era without America's involvement. The outcomes of this study provide some useful insights into preventing other countries from following the US example and better understanding China's position and capacity in keeping climate governance on the right track.

Coordination Mechanisms for the Two‐Echelon Newsvendor Model with Rapidly Responsive and Strategic Consumers

Aiming at the two-echelon newsvendor problem in which the market demand of commodities is random both in normal sales period and in liquidation period, this paper studies the pricing and ordering decision of retailers by using rational expectation equilibrium under the condition of considering consumersʼ strategic behavior and rapid response mechanism. Then, the decision-making problem under retailersʼ initial order quantity commitment is discussed, as well as the effect of commitment mechanism on supply chain performance. On this basis, both the two-part pricing contract and revenue-sharing contract are introduced to achieve supply chain coordination aiming at the profit maximization under the initial order quantity commitment mechanism. The results show that the rapid response mechanism can reduce the negative impact of consumers’ strategic behavior, and the initial order quantity commitment can further reduce the impact and improve the retailers’ profit. Both the two-part pricing contract and revenue-sharing contract can coordinate the whole supply chain in which the two-part pricing contract can distribute profit arbitrarily between manufacturers and retailers while the revenue-sharing contract can share risks among members of the supply chain.

ANALISIS PELAKSANAAN KEBIJAKAN KOTA LAYAK ANAK (STUDI KASUS PELAKSANAAN PROGRAM RUANG BERMAIN RAMAH ANAK DI RUANG TERBUKA HIJAU KACANG MAYANG KOTA PEKANBARU)

As a form of Child Friendly City policy, the Child Friendly Playroom (RBRA) program is realized. Pekanbaru's achievement as a city that provides certified child-friendly play spaces is a manifestation of its initial commitment to building and giving children the right to develop and develop children in its playground located at RTH Kacang Mayang, Pekanbaru City. This study aims to see the implementation of child-friendly city policies in the Kacang Mayang Green Open Space, Pekanbaru City. This type of research is qualitative with descriptive analysis. Qualitative research is a research procedure that produces descriptive data in the form of written or spoken words from people and observed behavior from the phenomena that occur. This study examines the facts of the implementation of the Child Friendly Playroom Program in Pekanbaru City. The data collection technique in this research uses literature study by collecting data and documents from various references that will be used as references. The results of this study are that the implementation of child-friendly city policies (a case study of the implementation of the Child Friendly Playroom Program in the Kacang Mayang Green Open Space in Pekanbaru City) has gone well. This is shown by the availability of adequate facilities, infrastructure and facilities to become child-friendly green open spaces. Received a good assessment and determined that Pekanbaru's Kacang Mayang Green Open Space was suitable for children, proving the government's commitment to realizing a child-friendly city through the provision of child-friendly green open spaces. In implementing child-friendly city policies, there are several factors that influence, namely: completeness of the facilities; Accessibility; Safety and comfort; Government commitment.

In Silico: Where Next?

Everyone agrees that we do not yet understand how brains work, neither well enough to satisfactorily explain basic functions such as memory nor to design effective interventions to restore mental health. This is one of the great scientific challenges of our era, with huge implications not only for human health but for insight into all animal life and for the development of future technologies. How should resources be invested to foster the necessary leap toward understanding? Given the pressing societal need and the very high public expectations of neuroscience, stoked by TED talks, New York Times articles, and sci fi, the pressures riding on choices of funding targets are enormous. Against this background, 2013 was a banner year for the brain: both the European Union and the United States agreed to devote unprecedented support specifically to neuroscience. The European Union funded the billion-dollar Human Brain Project (HBP; Amunts et al, 2016), whose centerpiece was a team science effort to develop neuroinformatics infrastructure and to expand the Blue Brain Project (Markram, 2006), a high-fidelity biophysically realistic computational model of brain tissue. In the United States, the BRAIN Initiative launched with an initial commitment of $100 million and the appointment of a panel of respected scientists who met over months to identify major gaps and promising directions in neuroscience (Jorgenson et al., 2015). Government agencies then formulated funding opportunities that supported individual labs or small teams to develop new technologies to record, stimulate, analyze, and interpret neural activity. These efforts stimulated brain initiatives in several other countries, including Japan, Korea, and China (Huang and Luo, 2015; Grillner et al., 2016). Almost 10 years later, it is timely to look back at some of the large-scale neuroscience efforts of the past decade and the routes they …

Identifying opportunities to strengthen school food environments in the Pacific: a case study in Samoa

BackgroundDespite global recommendations to prioritise policies that create healthy food environments within education institutions, the implementation of effective healthy school food policies has proved challenging for many countries. This study examined the experience of Samoa subsequent to the 2012 introduction of a stronger policy to improve the healthiness of school food environments. Our aim was to identify opportunities to strengthen healthy school food policy implementation in Samoa and other comparable contexts.MethodsWe used a qualitative case study approach, underpinned by policy science theory. In 2018, we conducted in-depth semi-structured interviews with 30 informants, coupled with analysis of relevant documents, to generate a detailed understanding of the relevant policy implementation processes in Samoa, and the perspectives and capacities of key implementation actors. Data collection and analysis were guided by the Health Policy Analysis Triangle, supplemented by other policy theories relevant to policy process.ResultsSamoa’s school food policy operationalizes international ‘best practice’ recommendations. We found health policymakers and leaders in Samoa to be strongly committed to improving school food environments. Despite this, there continued to be challenges in ensuring compliance with the school nutrition standards. Key issues that negatively impacted the policy’s effectiveness were the lack of priority given to school food by stakeholders outside of health, the high prevalence of unhealthy food in the areas immediately surrounding schools, vendor knowledge and capacity, and the high degree of agency exercised by actors in and around the school. We noted several opportunities for policies to be effectively implemented and sustained. Respondents identified community-level leaders as potentially pivotal stakeholders, particularly where school governance arrangements draw heavily on community representation.ConclusionsSustained and effective implementation of healthy school food policies requires continued engagement from political and community leaders, beyond initial commitment. There is potential to capitalize on political will for diet-related NCD prevention by more clearly demonstrating the institutional and operational requirements for effective and sustained implementation. Strong incentives for compliance and effective enforcement mechanisms are also likely to be crucial to success.

Molecular origins of reduced activity and binding commitment of processive cellulases and associated carbohydrate-binding proteins to cellulose III

Efficient enzymatic saccharification of cellulosic biomass into fermentable sugars can enable production of bioproducts like ethanol. Native crystalline cellulose, or cellulose I, is inefficiently processed via enzymatic hydrolysis but can be converted into the structurally distinct cellulose III allomorph that is processed via cellulase cocktails derived from Trichoderma reesei up to 20-fold faster. However, characterization of individual cellulases from T. reesei, like the processive exocellulase Cel7A, shows reduced binding and activity at low enzyme loadings toward cellulose III. To clarify this discrepancy, we monitored the single-molecule initial binding commitment and subsequent processive motility of Cel7A enzymes and associated carbohydrate-binding modules (CBMs) on cellulose using optical tweezers force spectroscopy. We confirmed a 48% lower initial binding commitment and 32% slower processive motility of Cel7A on cellulose III, which we hypothesized derives from reduced binding affinity of the Cel7A binding domain CBM1. Classical CBM–cellulose pull-down assays, depending on the adsorption model fitted, predicted between 1.2- and 7-fold reduction in CBM1 binding affinity for cellulose III. Force spectroscopy measurements of CBM1–cellulose interactions, along with molecular dynamics simulations, indicated that previous interpretations of classical binding assay results using multisite adsorption models may have complicated analysis, and instead suggest simpler single-site models should be used. These findings were corroborated by binding analysis of other type-A CBMs (CBM2a, CBM3a, CBM5, CBM10, and CBM64) on both cellulose allomorphs. Finally, we discuss how complementary analytical tools are critical to gain insight into the complex mechanisms of insoluble polysaccharides hydrolysis by cellulolytic enzymes and associated carbohydrate-binding proteins.

Japan-China 2008 Agreement: Common-Pool Resource Governance Problem

This research aims to answer the reason behind the stalled progress of dispute settlement in East China Sea between Japan and China, despite a high initial commitment to cooperate under Japan-China Agreement on Cooperation for the Development of East China Sea Resources framework. This research was done qualitatively by amassing reliable literatures and relevant official documents. In accomplishing the research objective, this article employs common-pool resource (CPR) and security dilemma concepts to analyze the collected data. This research finds that the reason why the 2008 Agreement, which intended to make East China Sea as common-pool resource for Japan and China, did not work is due to the lack of institutional supply and commitment. The insufficient institutional supply was occurred since Japan and China, as appropriators of the CPR, were seeking less binding and more flexible rules. Even though that maximum result could be attained through high commitment, both Japan and China were not assured about each other intentions. Thus, the cooperation is stalled.

Real-time comprehension of garden-path constructions by preschoolers: A Mandarin perspective

AbstractThe present study investigated whether 4- and 5-year-old Mandarin-speaking children are able to process garden-path constructions in real time when the working memory burden associated with revision and reanalysis is kept to minimum. In total, 25 4-year-olds, 25 5-year-olds, and 30 adults were tested using the visual-world paradigm of eye tracking. The obtained eye gaze patterns reflect that the 4- and 5-year-olds, like the adults, committed to an initial misinterpretation and later successfully revised their initial interpretation. The findings show that preschool children are able to revise and reanalyze their initial commitment and then arrive at the correct interpretation using the later-encountered linguistic information when processing the garden-path constructions in the current study. The findings also suggest that although the 4-year-olds successfully processed the garden-path constructions in real time, they were not as effective as the 5-year-olds and the adults in revising and reanalyzing their initial mistaken interpretation when later encountering the critical linguistic cue. Taken together, our findings call for a fine-grained model of child sentence processing.

Toward a Bias-Free and Inclusive Medical Curriculum: Development and Implementation of Student-Initiated Guidelines and Monitoring Mechanisms at One Institution.

As research and attention on implicit bias and inclusiveness in medical school is expanding, institutions need mechanisms for recognizing, reporting, and addressing instances of implicit bias and lack of inclusiveness in medical school curricular structures. These instances can come as a result of a lack of both awareness and communication around these sensitive issues. To identify and address cases of implicit bias in the medical school curriculum, a student-led initiative at Columbia University Vagelos College of Physicians and Surgeons (VP&S) developed guidelines and a bias-reporting process for educators and students. The guidelines, co-created by students and faculty, help educators identify and address implicit bias in the curriculum. Furthermore, to allow for continued development of the curriculum and the guidelines themselves, the group adapted an existing learning environment reporting and review process to identify and address instances of implicit bias. In the first year since their implementation, these tools have already had an impact on the learning climate at VP&S. They have led to enhanced identification of implicit bias in the curriculum and changes in instructional materials. The courage and inspiration of the students and the initial investment and commitment from the administration and faculty were crucial to this rapid effect. The authors present an approach and resources from which other institutions can learn, with the goal of reducing implicit bias and improving inclusiveness throughout medical education. In the long run, the authors hope that these interventions will contribute to better preparing future providers to care for all patients equitably.

Stage-Gate Escalation

In this article, we review resource allocation at former handset maker Sony Ericsson. Three observations reveal how innovation projects can escalate through a stage-gate process that is meant to minimize initial commitment. First, uncertainty makes business cases hard to disconfirm in the early stages of project development. Second, as information that can be used to disconfirm business cases becomes more readily attainable in later stages of development, an increasing focus on project completion discourages the updating of business cases. Third, if business cases are revised negatively, the heightened organizational attention appears to make discontinuations less likely. We contextualize these three findings, replicate them with data from a second company, and discuss their potential implications for organizing innovation under uncertainty.

Nurses' experiences of their decision-making process when participating in clinical trials during the 2014-2016 West African Ebola crisis.

Due to the absence of a licenced vaccine or drug for treatment of Ebola patients during the 2014-2016 West Africa outbreak, frontline nurses were at increased risk of exposure. Hence, they were prioritized to participate in clinical trials to receive experimental therapeutics. To our knowledge no study has explored the nurses' experiences of their decision-making process when volunteering in clinical trials using unproven agents, which is the purpose of this qualitative study. This study, part of a larger Ebola study, thematically analyzed the interview data of nine nurses recruited from Sierra Leone, Guinea and Liberia; of which four joined a convalescent plasma trial and five a vaccine trial. In their decision-making process to partake in a clinical trial, nurses identified two distinct decision points: the initial commitment followed by the point of no return when they presented themselves to participate. Each of these decisions were influenced by risk versus benefits calculations, and contextual factors. Results showed the need for more health education and communication around the unproven agents in order for nurses to make informed decisions.

Midwifery leadership, advocacy and action to improve maternal health in PNG

Abstract Background The SDG target for maternal mortality is less than 70 per 100,000 live births; in Papua New Guinea, it is estimated to be 145. PNG will require significant resources and strong leadership to meet the 2030 target. The PNG Midwifery Leadership Buddy Program (Buddy Program), funded and coordinated by Rotary, offers an innovative model to improve maternal health, which may be transferable to other low-middle-income countries. Objectives The Buddy Program aims to build midwifery leadership resulting in improved outcomes in PNG. As partners, midwives from PNG and Australia undertake leadership training in Port Moresby and enter a reciprocal peer support relationship. Over 12 months, they support each other in their professional roles and progress a quality improvement project. Results Three cohorts of midwives (18 from each country), have participated in the leadership training and the first group has completed 12 months of peer support. Participants have reported increased confidence for leadership, action and advocacy. There has been some communication challenges and variation in expectations, predominately due to cultural differences. The Buddy Program has resulted in a number of tangible projects including the introduction of family planning education at a local school and University, introduction of respectful care in pregnancy charter and increased surveillance and treatment of pregnant women with anaemia. Interestingly, a number of participants have continued to support each other beyond the initial 12-month commitment. Conclusions Supportive partnerships that grow midwifery leadership hold significant potential to increase the quality of maternity care and reduce preventable maternal deaths in low-middle-income countries. Key messages Midwifery leadership plays a vital role in addressing the SDG targets for maternal health. The Buddy Program offers an innovative model to progress the agenda for universal access to quality maternity care.

Organizational Characteristics and Readiness for Tobacco-Free Workplace Program Implementation Moderates Changes in Clinician's Delivery of Smoking Interventions within Behavioral Health Treatment Clinics.

BackgroundSmoking is elevated amongst individuals with behavioral health disorders, but not commonly addressed. Taking Texas Tobacco Free is an evidence-based, tobacco-free workplace program that addresses this, in-part, by providing clinician training to treat tobacco use in local mental health authorities (LMHAs). This study examined organizational moderators of change in intervention delivery from pre- to post-program implementation. MethodsLMHA leaders completed the Organizational Readiness for Implementing Change (ORIC) and provided organization demographics pre-implementation. Clinicians (N = 1237) were anonymously surveyed about their consistent use of the 5As (Asking about smoking; Advising clientele to quit; Assessing willingness to quit; Assisting them to quit; Arranging follow-up) pre- and post-program implementation. Adjusted generalized linear mixed models were used for analyses (responses nested within LMHAs), with interaction terms used to assess moderation effects. ResultsClinician delivery of 5As increased pre- to post-implementation (p < .001). LMHAs with fewer employees (ref = ≤300) demonstrated greater increases in Asking, Assessing, and Assisting over time. LMHAs with fewer patients (ref = ≤10 000) evinced greater changes in Asking over time. Less initial ORIC Change Efficacy, Change Commitment, and Task Knowledge were each associated with greater pre- to post-implementation changes in Asking. Less initial Task Knowledge was associated with greater increases in Advising, Assessing, and Assisting. Finally, less initial Resource Availability was associated with greater increases in Assisting (all moderation term ps < .025).ConclusionThe smallest and least ready LMHAs showed the largest gains in tobacco cessation intervention delivery; thus, low initial readiness was not a barrier for program implementation, particularly when efficacy-building training and resources are provided.ImplicationsThis study examined organizational moderators of increases in tobacco cessation treatment delivery over time following the implementation of a comprehensive tobacco-free workplace program within 20 of 39 LMHAs across Texas (hundreds of clinics; servicing >50% of the state) from 2013 to 2018. Overall, LMHAs with fewer employees and patients, and that demonstrated the least initial readiness for change, evinced greater gains in intervention delivery. Findings add to dissemination and implementation science by supporting that low initial readiness was not a barrier for this aspect of tobacco-free workplace program implementation when resources and clinician training sessions were provided.

Preferences Regarding a Web-Based, Neighborhood-Level Intervention Program to Promote Household Energy Conservation

ABSTRACT The aim of this study is to investigate people’s willingness to participate in and their preferences regarding a web-based, neighborhood-level energy conservation program. We created a hypothetical program that incorporates several intervention strategies and presented it to 715 respondents in the form of a stated choice experiment. A strong majority of participants indicated that they would be willing to join such a program. Their preferences as to how the program should be constructed reflected interest in personalized feedback, privacy protection, monetary incentives for reducing energy use, and a relatively short-term initial commitment. However, there was variation in people’s taste for such attributes. We conclude with reflections on how to design and implement a web-based intervention program and on future research possibilities.

The Limits of the Commune: A Review of The Mystery of the Kibbutz

Ran Abramitzky's book, The Mystery of the Kibbutz: Egalitarian Principles in a Capitalist World, tries to answer the questions of why the communal kibbutz worked so well in Israel's formative years and what limits its current success in modern Israel. Initial ideological commitment and the special circumstances of Israel's founding led to unusual success when combined with well-thought-out rules on behavior and entry. Over time, the commitment to socialistic income sharing has not worked so well, given modern technology and global commerce. The author links up these ideas to the broader issue of organizational structure but misses out on some opportunities to test the ideas further. (JEL D31, D63, D82, J24, P13, Q13)

Adipogenic commitment induced by green tea polyphenols remodel adipocytes to a thermogenic phenotype

The potential contribution of green tea (GT) to the development of thermogenic/beige cells have been scarcely investigated. Here we investigated if the beneficial effects of GT in the induction of thermogenic/beige adipocytes results from an initial cell commitment during adipogenesis. Male C57Bl/6 mice (3 months) were divided into 3 groups: Control (chow diet), Obese (cafeteria diet), and Obese + GT. Mice received GT gavage (500 mg/kg of BW) over 12 weeks (5 days/week), after 4 weeks of diet, totalizing 16 weeks of experimentation. GT treatment increased energy expenditure (EE) in mice fed with cafeteria-diet leading to reduced BW gain, decreased adiposity, reduced inflammation, and improving insulin sensitivity. Those phenotypes were associated with enhanced expression of oxidative, thermogenic and beige genes. GT induced a futile cycle through de novo lipogenesis activating the thermogenic pathway. Induction of beige phenotype occurs autonomously in adipocytes and involves the PPARγ/FGF21/AMPK/UCP1 pathway. Our study identified that metabolic changes caused by GT may involve the temporal expression of PPARγ promoting the induction of thermogenic cells by reprogramming initial steps of adipocyte commitment.

Covid-19 as a ‘breaching experiment’: exposing the fractured society

ABSTRACT In this brief paper, I argue that the coronavirus pandemic is functioning like an ethnomethodological ‘breaching experiment’. In short, it is putting a gigantic spanner in the works of neoliberal governance, in the process exposing the widening cracks and fissures of what I have called the ‘fractured society’. I begin by recalling Garfinkel’s notion of the breaching experiment and by listing the principal attributes of the fractured society. I then explore the response to the coronavirus in the UK, from the government’s initial commitment to ‘herd immunity’ to its present policy of ‘muddling through’. The bulk of the remainder of this contribution addresses precisely how this global health crisis shines a harsh and unforgiving searchlight on the strategies and policies pursued by governments in the UK since 2010, and most especially after the passing of the Health and Social Care Act of 2012. In the closing paragraphs, I examine possible scenarios for a post-fractured society, making particular use of Fraser’s concepts on ‘reactionary’ versus ‘progressive populism’, and conclude with a comment on sociology and engagement.

Abstract P1-14-01: Feasibility study of moderate dose omega 3 fatty acid supplementation in premenopausal women at high risk for breast cancer considering future pregnancy

Abstract Background: 11% of women developing breast cancer are pre-menopausal women of childbearing potential under the age of 45. Pregnancy and breast feeding provide long term protection for breast cancer when they occur at an early age. The reasons for protection are poorly understood but likely involve both changes in the immune microenvironment and ductal and lobular epithelial differentiation. This pilot study is addressing a potential prevention strategy in a population otherwise excluded from breast cancer prevention trials and not eligible for standard of care chemoprevention. Methods: Eligible individuals included pre-menopausal women ages 21-40 that were considering future pregnancy and are at high risk for breast cancer based on family history, prior precancerous biopsy, or 5-year Gail model risk estimate of ≥ 1.7% or 10-year Tyrer-Cuzick risk of 2x population risk as listed in the model. Participants were enrolled and baseline tissue collection included random periareolar fine-needle aspiration (RPFNA) of breast, as well as collection of blood, urine and stool. Women were asked to take two capsules of Omega-3-Acid Ethyl Esters daily (a total of 750 mg DHA and 930 mg EPA) for six months. Post-intervention visit included repeat tissue collection. If women were pregnant at time of post-intervention visit, RPFNA was not done. Baseline and post-intervention DHA Food Frequency Questionnaire (FFQ) and the BCPT Questionnaire were administered. The intervention length was shortened for some participants due to the study ending. Objectives: 1) To determine feasibility of a breast cancer prevention intervention study in this cohort of pre-menopausal women at high risk for breast cancer and considering future pregnancy, 2) measure compliance with the omega-3 fatty acid supplement in this population, 3) identify novel biomarkers modulated by moderate dose omega-3 fatty acids in this population. Results: Ten women were successfully enrolled at an average rate of 1.5/month from a single center high risk breast clinic. Of the ten women enrolled, median age was 33 years (range 22-37, ±5.04 stdev), 70% married, 80% Non-Hispanic White, 10% of Ashkenazi Jewish descent and 40% reported having a genetic mutation. Feasibility was achieved with 80% (8 out of 10) of participants returning for post-intervention visit. Reasons given for discontinuation of study were (n=1) side effect from supplement (bloating) and (n=1) scheduling conflicts. Of the eight women who completed the off study visit, two chose not to undergo the off study RPFNA due to discomfort with initial procedure or time commitment. Self-reported pill count showed an average of three missed pills/month. Grade 1 related adverse events reported included odor, nausea and flatulence. Post-intervention, more participants reported diarrhea, vaginal discharge and bleeding, weight gain, general aches and dizziness on BCPT items compared to baseline. Change in benign breast tissue biomarkers will be reported including breast tissue cytomorphology, Ki67, fatty acid analysis and selected gene expression. Conclusion: It is feasible to recruit premenopausal women considering future pregnancy to a breast cancer prevention trial with a minimally invasive sampling procedure. Results from this trial will inform a larger randomized prevention trial. Citation Format: Lauren E Nye, Jennifer R Klemp, Kandy R Powers, Anne P O'Dea, Kendra A Cruz, Amy L Kreutzjans, Trina Metheny, Teresa A Phillips, Susan E Carlson, Bruce F Kimler, Carol J Fabian. Feasibility study of moderate dose omega 3 fatty acid supplementation in premenopausal women at high risk for breast cancer considering future pregnancy [abstract]. In: Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P1-14-01.

Self-Monitoring as a Personality Variable in Tinto’s Theory of Integration

One weakness of Tinto’s (1993) model is its inability to identify early dropouts (Webb, 1988), which may be due to the theory’s inattention to personality traits. Self-monitoring (Snyder, 1974) may be an important trait related to dropout. This study hypothesized low self-monitors, compared to high self-monitors would be more likely to (1) have higher initial commitment levels, (2) achieve higher academic integration, (3) accomplish greater social integration, and (4) persist in college. Path analysis confirmed all hypotheses. Self-Monitoring was demonstrated to be an important personal characteristic in Tinto's Theory. Application of theses findings are discussed.