Quarantine Of Individuals Research Articles

Dynamics of information diffusion and disease transmission in time-varying multiplex networks with asymmetric activity levels

While the interaction between information and disease in static networks has been extensively investigated, many studies have ignored the characteristics of network evolution. In this study, we construct a new two-layer coupling model to explore the interactions between information and disease. The upper layer describes the diffusion of disease-related information, and the lower layer represents the disease transmission. We then use power-law distributions to examine the influence of asymmetric activity levels on dynamic propagation, revealing a mapping relationship characterizing the interconnected propagation of information and diseases among partial nodes within the network. Subsequently, we derive the disease outbreak threshold by using the microscopic Markov-chain approach (MMCA). Finally, we perform extensive Monte Carlo (MC) numerical simulations to verify the accuracy of our theoretical results. Our findings indicate that the activity levels of individuals in the disease transmission layer have a more significant influence on disease transmission compared with the individual activity levels in the information diffusion layer. Moreover, reducing the damping factor can delay disease outbreaks and suppress disease transmission, while improving individual quarantine measures can contribute positively to disease control. This study provides valuable insights into policymakers for developing outbreak prevention and control strategies.

Behavioral and psychosocial factors and their effects on insomnia among people undergoing entry quarantine in hotels during COVID-19 pandemic: a cross-sectional study in Guangzhou, China

BackgroundThe COVID-19 pandemic continues to impact global health and China requires a 14-day quarantine for individuals on flights with positive COVID-19 cases. This quarantine can impact mental well-being, including sleep. This study aims to examine the impact of psychosocial and behavioral factors on insomnia among individuals undergoing quarantine in hotels.MethodsThis study was a cross-sectional survey carried out in Guangzhou, China. The data was gathered through online questionnaires distributed to international passengers who arrived in Guangzhou on flights and were required to undergo a 14-day quarantine in hotels arranged by the local government. The questionnaires were sent to the participants through the government health hotline "12,320."ResultsOf the 1003 passengers who were quarantined, 6.7% reported significant anxiety and 25.0% had varying degrees of insomnia. Anxiety was positively associated with insomnia (β = 0.92, P < 0.001), while collectivism (β = -0.07, P = 0.036), indoor exercise (β = -0.50, P < 0.001), and the perceived people orientation of the public health service (β = -0.20, P = 0.001) were negatively associated with insomnia. The study also identified moderating effects, such that a higher sense of collectivism, a greater frequency of indoor exercise, and a higher perception of the people-oriented of the public health service were associated with a lower impact of anxiety on insomnia. These moderating effects were also observed in participants with varying degrees of insomnia.ConclusionsThis study reveals that a proportion of people undergoing entry quarantine experience insomnia and confirms how psychosocial and behavioral factors can alleviate insomnia in this population.

Lessons From the Wrong Isolation Policy Violating Human Rights for Leprosy in Japan.

Leprosy, caused by Mycobacterium leprae , is one of the so-called "neglected tropical diseases" and is found today mainly in Africa, Asia and South America. Although oral antibiotics capable of curing leprosy are now available, the disease is still misunderstood and feared by the public because of the unsightly deformities that it may cause. In Japan, leprosy has been present since the 8th century and was regarded as a hereditary disease; people avoided marrying into a family with a member affected by leprosy. At the beginning of the 20th century, the Japanese government instituted a policy of lifetime quarantine of individuals with leprosy to eradicate the disease, thereby purposely disseminating negative and inaccurate perceptions of the disease as deadly and highly contagious and fostering a long-lasting prejudice among the general public towards those affected. Even after effective treatments became available, the government continued quarantining patients until 1996. The government has since then apologized to the patients for violating their constitutionally guaranteed human rights. Children with leprosy and children born to parents with leprosy were also victims of the policy and prejudice created. We describe herein the history of leprosy-related policies in Japan to emphasize the importance of balancing public health policy with human rights.

Da li je čin obaveznog i produženog bolničkog karantina faktor rizika za narušeno mentalno zdravlje kod osoba sa potvrđenom infekcijom COVID-19?

Background. Coronavirus disease 2019 (COVID-19) affects mental health. Our study aimed to investigate whether the act of mandatory and prolonged in-hospital quarantine is a contributing risk factor for impaired mental health among individuals with confirmed COVID-19 infection. Materials and methods. A mixed survey-based cross-sectional study included 300 COVID-19 patients who filled Depression, Anxiety, and Stress Scales 21 (DASS-21), a 36-item health survey of the Medical Outcomes Study Short Form (SF-36), Insomnia Severity Scale (ISS), Impact of Event Scale (IES) with two subscales -Intrusion (IES-I) and Avoidance (IES-AS), and a questionnaire designed for research purposes. Results. Lower scores on IES-AS, higher scores on IES-I, and in-hospital quarantine are good predictors of high results on the Stress subscale. In-hospital quarantine, lower IES-AS scores, higher IES-I scores, and male gender are significant predictors of higher scores on the Depression subscale. Also, higher scores on IES-I as well as in-hospital quarantine are significant predictors of higher scores on the Anxiety subscale. The presence of insomnia was more pronounced in in-hospital quarantined individuals, while the levels of stress, anxiety, and depression were nearly twice as pronounced. Conclusion. Mandatory in-hospital quarantine of individuals with confirmed COVID-19 infection is a contributing risk factor for impaired mental health.

Stress, anxiety, and depression in times of COVID-19: Gender, individual quarantine, pandemic duration and employment.

This study explores the inter-relationship between emotional distress in adults and gender, quarantine experiences, pandemic duration, and employment. An online cross-sectional online survey comprised 943 Israelis. The link to the survey was distributed via different personal and academic social networking sites (e.g., Facebook, WhatsApp, and Twitter). The survey was administered using the online survey portal Google Forms. Participants addressed questions about their socio-demographic characteristics (e.g., gender, age, family status, employment, and quarantine experiences) and ranked their levels of stress, anxiety, and depression using the Hebrew version of the Depression, Anxiety and Stress Scale-DASS-21. The majority of the respondents (72%) were women, 39% experienced quarantine, and 55% were unemployed. About 42% experienced a short-term pandemic (one lockdown), and the rest experienced a continuous pandemic (two lockdowns). The MANCOVA results, controlling for family status, indicated that women and unemployed participants reported higher stress, anxiety, and depression levels than men and employed participants. Participants who experienced individual quarantine reported higher anxiety and depression. Furthermore, there was a significant interaction between gender, employment, and pandemic duration. The experience of individual quarantine intensified the stress, anxiety, and depression for both employed and unemployed women. Conversely, the quarantine intensified stress, anxiety, and depression only for unemployed men, whereas the quarantine did not affect stress, anxiety, and depression among employed men. Employment is a critical factor regarding men's emotional state during such stressful situations as the COVID-19 pandemic. Furthermore, individual quarantine and long-term pandemics are associated with opposite outcomes regarding individual mental health. The individual quarantine is associated with increased anxiety and depression, while a long-term, continuous pandemic is associated with decreased stress.

Retrospective detection of asymptomatic monkeypox virus infections among male sexual health clinic attendees in Belgium

The magnitude of the 2022 multi-country monkeypox virus (MPXV) outbreak has surpassed any preceding outbreak. It is unclear whether asymptomatic or otherwise undiagnosed infections are fuelling this epidemic. In this study, we aimed to assess whether undiagnosed infections occurred among men attending a Belgian sexual health clinic in May 2022. We retrospectively screened 224 samples collected for gonorrhea and chlamydia testing using an MPXV PCR assay and identified MPXV-DNA-positive samples from four men. At the time of sampling, one man had a painful rash, and three men had reported no symptoms. Upon clinical examination 21–37 days later, these three men were free of clinical signs, and they reported not having experienced any symptoms. Serology confirmed MPXV exposure in all three men, and MPXV was cultured from two cases. These findings show that certain cases of monkeypox remain undiagnosed and suggest that testing and quarantining of individuals reporting symptoms may not suffice to contain the outbreak.

Differences in post-traumatic growth: Individual quarantine, COVID-19 duration and gender.

ObjectiveThis study focuses on positive effects of the COVID-19 pandemic and aims to identify associations between gender, individual quarantine and duration of the COVID-19 (short- medium- and long-term pandemic), and posttraumatic growth (PTG).MethodThe data was collected via an online survey in Israel, and included 1,301 participants, 543 participants experienced short-term pandemics, 428 participants experienced medium-term pandemics and 330 participants experienced long-term pandemics. Most of the participants were female (73.6%), ranging from 18 to 89 years-old. The participants answered questions about their demographic background, individual quarantine experiences and ranked their PTG level.ResultsThe results indicate a significant main effect of gender and pandemic duration (short-, medium- and long-term pandemic). Women reported higher PTG levels than men, and participants experiencing short-term pandemic reported significantly lower PTG levels than participants experiencing medium- or long-term pandemic. There was also a significant interaction between gender and pandemic duration regarding PTG and a significant interaction in PTG by gender, pandemic duration and individual quarantine.ConclusionThe discussion addresses the findings in the context of traditional gender roles and gender differences in finding meaning and worth in home confinement situations.

Mental health services at the Tokyo 2020 Olympic and Paralympic Games during the COVID-19 pandemic

Mental health services at the Tokyo 2020 Olympic and Paralympic Games during the COVID-19 pandemic

Strategies to aid self-isolation and quarantine for individuals with severe and persistent mental illness during the COVID-19 pandemic: A systematic review.

BackgroundIndividuals with severe and persistent mental illness (SPMI) have a higher risk of contracting COVID‐19 than individuals without SPMI. In combination with physical distancing, hygiene protocols, and vaccines, quarantine and self‐isolation are primary means of viral containment. However, individuals with SPMI may experience more difficulties with mandated quarantine or self‐isolation because of their illness(es), stigma, and marginalization. To date, there is a lack of consensus on strategies that could aid such individuals in completing isolation.AimThis review aimed to synthesize evidence for interventions to support self‐isolation and mandated quarantine for COVID‐19 among individuals with SPMIs.MethodsWe followed the PRISMA guidelines, searching 19 electronic databases (9 published literature registries and 10 gray literature sources). We looked for relevant randomized controlled trials, quasi‐experimental studies, and program evaluations of the effectiveness of relevant psychosocial, pharmacological, harm reduction, and addiction management strategies to support isolation settings or quarantine requirements for individuals with any SPMI (e.g., any mental disorder, substance use disorder, or their combination).FindingsOf 10,298 total records that were located, 5582 were duplicate citations. Upon screening the remaining 4716 unique records by title and abstract, we excluded a further 3562 records. Only one original article met our inclusion criteria after reviewing the full texts of the remaining 1154 citations. To support individuals experiencing homelessness during the COVID‐19 pandemic, San Francisco developed an isolation hotel that reduced COVID‐19 hospital strain for 1009 participants (25% had a mental health disorder and 26% had a substance use disorder). While 81% completed their hotel stay, 48 patients had behavioral health needs that exceeded the hotel's capabilities. No other studies met our review's eligibility criteria. Most articles located by the search simply proposed solutions or discussed the challenges brought by COVID‐19 for people with SPMIs. While some documents went a step further (e.g., shelter guidance documents to support individuals experiencing homelessness), these rarely addressed individuals with SPMIs directly.ConclusionsThis systematic review evaluated evidence from published and gray literature on interventions to support self‐isolation and mandated COVID‐19 quarantine for individuals with SPMIs. Only one study met our inclusion criteria. This study found a beneficial effect of a dedicated isolation hotel for individuals experiencing homelessness and COVID‐19—where approximately 25%–50% of the study sample had a mental or substance use disorder. While there has been an abundance of COVID‐19 protocols in general, information for SPMIs is lacking. As the pandemic continues and we better prepare for future pandemics, developing protocols for supporting SPMIs in this context is imperative.

How is COVID-19 affecting the renewable energy sector and the electric power grid?

It is not new to say that clean energy is better than energy from fossil fuels. What's new is that the world has a unique opportunity to accelerate clean development by putting renewable energy at the center of Covid-19 economic recovery plans. The process began with the individual quarantine of people; the closure of businesses, the decrease in the workforce and cash flow of companies, serious problems in production affected many sectors, including the energy sector, and currently, ongoing construction in power generation facilities has come to a standstill. In this study, it was investigated how the epidemic affected the renewable energy sector. Overall, energy demand fell but did not collapse completely. The most significant impact is felt in production centers and businesses where industrial demand is decreasing, but there is an increase in residential customer demand. Along with the decrease in natural gas prices, the decrease in demand caused the prices in the electricity wholesale markets to decrease. Although the fossil resources demand significantly decreased during the epidemic period, it remains uncertain for the post-epidemic period, there are signs that there may be changes in the global market structure, but the impact on renewable energy investments may be limited. On the renewable energy side, where energy investments have decreased significantly due to the epidemic, many investor companies are suffering from disruptions in the supply chain. However, the recovery of activities in China, the largest producer, will significantly reduce the negative impact in the short term.

The Need for a Paradigm Shift to Person-Centered Medicine during Pandemic Times

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has completely changed how the world looks at medicine. Unfortunately, the larger focus has been on the physical health only – epidemiology, clinical features, prevention of transmission, and management and there is very little focus on mental health and stigmatization. The 2019 coronavirus disease (COVID-19) has caused universal psychosocial impact by causing emotional disturbances, economic burden, and financial losses on a massive scale. Effects such as posttraumatic stress disorder, depression, anxiety, obsessive–compulsive symptoms, and insomnia in the post infection period have been reported among COVID-19 survivors. With disease progression, clinical symptoms become severe and infected patients may develop psychological problems. With exponential growth in the number of daily COVID-19 cases since March, 2021, India reported more than 400,000 new cases daily on May 1, 2021. India's COVID-19 surge could have become a regional disaster impacting all of south Asia. However, India has successfully avoided that disaster by strengthening the surveillance systems, imposing travel restrictions, lockdowns, and mandatory travel quarantine for individuals returning from infected areas. These were necessary to control the spread of SARS-CoV-2. The situation in India required urgent, bold measures and close cooperation between India and the global community. Currently, free vaccinations for the whole population are being given. With 1.4 billion people, this is going to be a massive effort. The pandemic and the aftermath need a paradigm shift from our traditional medical care models to one that is person centered. A person-centered model of care will be best solution here and all across the world. This is especially so, when we are fighting a disastrous pandemic.

Social Intervention by the Numbers: Evidence Behind the Specific Public Health Guidelines in the COVID-19 Pandemic.

Social Intervention by the Numbers: Evidence Behind the Specific Public Health Guidelines in the COVID-19 Pandemic.

Experiences of persons in COVID-19 institutional quarantine in Uganda: a qualitative study

BackgroundQuarantine has been adopted as a key public health measure to support the control of the Coronavirus disease (COVID-19) pandemic in many countries Uganda adopted institutional quarantine for individuals suspected of exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to be placed in institutions like hotels and/or hostels of institutions for at least 14 days. This study explored experiences of individuals who underwent institutional quarantine in Uganda to inform measures to increase its effectiveness and reduce its associated negative impact.MethodsWe conducted a qualitative description study using in-depth interviews with 20 purposively selected individuals who had spent time in institutional quarantine facilities. These were mainly phone-based interviews that were audio recorded and transcribed verbatim. Electronic data coding was conducted using Atlas.ti 7 software. Thematic content analysis was used to synthesize the findings with similar codes grouped to form sub-themes and ultimately study themes. The findings are presented thematically with typical participant quotes.ResultsStudy participants spent between 14 to 25 days in institutional quarantine. Four themes emerged describing the experiences of study participants during institutional quarantine, which determined whether participants’ experiences were positive or negative. These themes were: quarantine environment including facility related factors and compliance with COVID-19 measures; quarantine management factors of entity paying the costs, communication and days spent in quarantine; individual factors comprising attitude towards quarantine, fears during and post-quarantine and coping mechanisms; and linkage to other services such as health care and post-quarantine follow-up.ConclusionThe planning, management and implementation of the quarantine process is a key determinant of the experiences of individuals who undergo the measure. To improve the experience of quarantined individuals and reduce its associated negative impact, the pre-quarantine process should be managed to comply with standards, quarantined persons should be provided as much information as possible, their quarantine duration should kept short and costs of the process ought to be minimised. Furthermore, quarantine facilities should be assessed for suitability and monitored to comply with guidelines while avenues for access to healthcare for the quarantined need to be arranged and any potential stigma associated with quarantine thoroughly addressed.

An epidemiological model with voluntary quarantine strategies governed by evolutionary game dynamics.

During pandemic events, strategies such as social distancing can be fundamental to reduce simultaneous infections and mitigate the disease spreading, which is very relevant to the risk of a healthcare system collapse. Although these strategies can be recommended, or even imposed, their actual implementation may depend on the population perception of the risks associated with a potential infection. The current COVID-19 crisis, for instance, is showing that some individuals are much more prone than others to remain isolated. To better understand these dynamics, we propose an epidemiological SIR model that uses evolutionary game theory for combining in a single process social strategies, individual risk perception, and viral spreading. In particular, we consider a disease spreading through a population, whose agents can choose between self-isolation and a lifestyle careless of any epidemic risk. The strategy adoption is individual and depends on the perceived disease risk compared to the quarantine cost. The game payoff governs the strategy adoption, while the epidemic process governs the agent’s health state. At the same time, the infection rate depends on the agent’s strategy while the perceived disease risk depends on the fraction of infected agents. Our results show recurrent infection waves, which are usually seen in previous historic epidemic scenarios with voluntary quarantine. In particular, such waves re-occur as the population reduces disease awareness. Notably, the risk perception is found to be fundamental for controlling the magnitude of the infection peak, while the final infection size is mainly dictated by the infection rates. Low awareness leads to a single and strong infection peak, while a greater disease risk leads to shorter, although more frequent, peaks. The proposed model spontaneously captures relevant aspects of a pandemic event, highlighting the fundamental role of social strategies.

Modeling transmission dynamics of severe acute respiratory syndrome coronavirus 2 in São Paulo, Brazil.

INTRODUCTION Severe acute respiratory syndrome coronavirus 2 has been transmitted to more than 200 countries, with 92.5 million cases and 1,981,678 deaths. METHODS This study applied a mathematical model to estimate the increase in the number of cases in São Paulo state, Brazil during four epidemic periods and the subsequent 300 days. We used different types of dynamic transmission models to measure the effects of social distancing interventions, based on local contact patterns. Specifically, we used a model that incorporated multiple transmission pathways and an environmental class that represented the pathogen concentration in the environmental reservoir and also considered the time that an individual may sustain a latent infection before becoming actively infectious. Thus, this model allowed us to show how the individual quarantine and active monitoring of contacts can influence the model parameters and change the rate of exposure of susceptible individuals to those who are infected. RESULTS The estimated basic reproductive number, R o , was 3.59 (95% confidence interval [CI]: 3.48 - 3.72). The mathematical model data prediction coincided with the real data mainly when the social distancing measures were respected. However, a lack of social distancing measures caused a significant increase in the number of infected individuals. Thus, if social distancing measures are not respected, we estimated a difference of at least 100,000 cases over the next 300 days. CONCLUSIONS: Although the predictive capacity of this model was limited by the accuracy of the available data, our results showed that social distancing is currently the best non-pharmacological measure.

Experiences of quarantine for individuals during the COVID-19 outbreak in Kashmir: A qualitative study

Context: The coronavirus disease 2019 (COVID-19) outbreak originally occurred from Wuhan, China, in December 2019 and gradually spread to other countries in different parts of the world. The COVID-19 outbreak has led many countries ask people who have potentially come into contact with the infection to isolate themselves at home or in administrative quarantine facilities. Thus, quarantine at different levels, from individual to community, was seen as an effective measure of preventing the spread of this disease. Aims: The aim of the present study is to explore the experiences of quarantine for individuals returning from Bangladesh during the COVID-19 outbreak in Kashmir. Settings and Design: This study follows qualitative narrative design. Subjects and Methods: This study used an in-depth, semi-structured interview guide. Purposive sampling technique was used to select the participants who varied in terms of gender and age. Results: Despite individual differences, the experiences narrated by participants followed stages beginning before, during, and after ending the quarantine. The government authorities adopted a policy of mandatory quarantine to all the incoming passengers with the aim of preventing the spread of this pandemic. However, participants reported facing several issues such as shock and fear, feeling of isolation and loneliness, frustration and boredom, and loss of routine activities during this period. Conclusions: Quarantine as a method of preventing transmission of severe disease outbreak should be carefully used after effectively weighing its potential benefits and risks. The results of the study can be used to devise a proper policy framework and practice for effectively managing future quarantine and isolation-related health emergencies.

Assessing the impact of varying levels of case detection and contact tracing on COVID-19 transmission in Canada during lifting of restrictive closures using a dynamic compartmental model.

The coronavirus disease 2019 (COVID-19) pandemic began with a detected cluster of pneumonia cases in Wuhan, China in December 2019. Endemic transmission was recognized in Canada in early February 2020, making it urgent for public health stakeholders to have access to robust and reliable tools to support decision-making for epidemic management. The objectives of this paper are to present one of these tools-an aged-stratified dynamic compartmental model developed by the Public Health Agency of Canada in collaboration with Statistics Canada-and to model the impact of non-pharmaceutical interventions on the attack rate of COVID-19 infection in Canada. This model simulates the impact of different levels of non-pharmaceutical interventions, including case detection/isolation, contact tracing/quarantine and changes in the level of physical distancing in Canada, as restrictive closures began to be lifted in May 2020. This model allows us to highlight the importance of a relatively high level of detection and isolation of cases, as well as tracing and quarantine of individuals in contact with those cases, in order to avoid a resurgence of the epidemic in Canada as restrictive closures are lifted. Some level of physical distancing by the public will also likely need to be maintained. This study underlines the importance of a cautious approach to lifting restrictive closures in this second phase of the epidemic. This approach includes efforts by public health to identify cases and trace contacts, and to encourage Canadians to get tested if they are at risk of having been infected and to maintain physical distancing in public areas.

Natural history of SARS-CoV-2 infection in healthcare workers in Northern Italy

At present, the time-frame used for the quarantine of individuals with coronavirus disease 2019 (COVID-19) is the entire duration of symptoms plus 14 days after symptom recovery; however, no data have been reported specifically for healthcare workers (HCWs). In the study population of 142 HCWs with COVID-19, the mean time for viral clearance was 31.8 days. Asymptomatic subjects cleared the virus more quickly than symptomatic subjects (22 vs 34.2 days; P<0.0001). The presence of fever at the time of diagnosis was associated with a longer time to viral clearance (relative risk 11.45, 95% confidence interval 8.66–14.25; P<0.0001). These findings may have a significant impact on healthcare strategies for the future management of the COVID-19 pandemic.

Geoffrey Rose's Strategy of Prevention Applied to COVID-19.

Geoffrey Rose's Strategy of Prevention Applied to COVID-19.

What are the effects of quarantine for individuals traveling from a country with a declared COVID-19 outbreak?

What are the effects of quarantine for individuals traveling from a country with a declared COVID-19 outbreak?