Impact Of Biotechnology Research Articles

Bioremediation using genetically modified microorganisms for the degradation of environmental pollutants

Introduction: The study addressed the environmental problems caused by soil and water contamination due to the excessive use of agrochemicals and industrial wastes. It was pointed out that intensive agricultural production and population growth have increased the accumulation of pollutants, generating negative impacts on biodiversity and human health. In the face of this environmental crisis, remediation methods were explored, highlighting bioremediation as a sustainable and efficient strategy based on microorganisms for the elimination of pollutants.Development: Different bioremediation strategies were analyzed, differentiating between in situ and ex situ techniques. Processes such as biospraying, biostimulation and bioaugmentation, which allow the degradation of contaminants through microbial activity, were described. In addition, the impact of biotechnology on bioremediation was discussed, highlighting the use of omics tools and the application of genetically modified microorganisms to improve the efficiency of these processes. It was emphasized that genetic engineering and genome editing have made it possible to optimize the metabolic capacities of bacteria and fungi to transform toxic substances into less hazardous compounds.Conclusion: It was concluded that bioremediation represents a viable and ecological alternative for dealing with environmental contamination. However, its large-scale application still faces challenges, such as the regulation of genetically modified microorganisms and the need for more detailed studies on its long-term impact. The integration of new biotechnological technologies could optimize environmental remediation and ensure its sustainability in the future.

БІОЕКОНОМІКА ЯК ОСНОВА ЦІЛІСНОГО ПРОЕКТУВАННЯ ПОВОЄННОЇ РЕКОНСТРУКЦІЇ УКРАЇНИ

The article is devoted to the analysis of the processes of formation and support of the development of the bioeconomy in Ukraine in the conditions of war and post-war times, with a focus on its potential as a tool for economic restoration. The study proposes nationwide measures for the integration of the bioeconomy into post-war reconstruction programs, taking into account inter-sectoral interaction and biotechnological innovations. The issue of bioeconomy development is gaining particular relevance in the context of the post-war reconstruction of Ukraine, where it is necessary to combine economic growth, energy security, and environmental sustainability. In modern conditions, the bioeconomy can become a catalyst for the modernization of the economy, reducing dependence on fossil fuels and integrating the country into global economic processes. The aim is to study the current state of the bioeconomy in Ukraine, assess its resource potential, and develop a conceptual model for managing the innovative development of the bioeconomic sector for post-war reconstruction. The study aims to create a system of indicators for monitoring the effectiveness of bioeconomy management at the national and regional levels. The work uses the analysis of statistical data from BioUkraine, UABIO, and other sources, as well as systems approaches for assessing biomass resources and the biotechnology sector. Comparative analysis, modeling, and expert assessments were used to develop a conceptual management model and performance indicators. It was found that the bioeconomy in Ukraine has not yet been identified as a separate sector due to the lack of statistical classification. Still, its elements can be integrated into all sectors of the economy, in particular bioenergy and agrobiotechnology. A management model and a system of indicators were developed to assess the development of the bioeconomy, contributing to post-war renovation. Further research may focus on refining statistical methods for accounting for bioeconomic activity, developing regional strategies for biomass use, and assessing the impact of biotechnology on socio-economic indicators. The analysis of the integration of the bioeconomy with EU programs, such as the "Ukraine Facility", for attracting investment and technology is promising

Impact and prospects of reproductive biotechnologies on swine production in South America

In the evaluation of reproductive biotechnologies in pigs in South America, 72 key articles were selected through a comprehensive literature review and a sampling formula was used to ensure representativeness. Data collected from databases such as Scopus and Web of Science, assessed with a Likert scale and a reliability of 70.1% according to Cronbach's Alpha, reveal that artificial insemination (AI) is the most widely adopted technique, with more than 90% of commercial farms using it. In contrast, embryo transfer (ET) and in vitro fertilization (IVF) show limited adoption, with only 10% of farms applying them due to high costs and low efficiency. Multiple correspondence analysis (MCA) indicates that 55% of publications focus on AI and ET, while only 25% address IVF. The perception of information quality shows that 70% consider articles on AI to be clear, compared to only 40% for IVF. In conclusion, while AI remains prevalent and effective, adoption of ET and IVF faces significant barriers, suggesting an urgent need to improve the accessibility and efficiency of these advanced technologies and strengthen research in less-covered areas.

The Impact of Biotechnology in Shaping the Modern Agriculture

Advances in biotechnology have created new opportunities for food diversity in terms of both quantity and quality, as well as for collecting food in proportion to the world's expanding population and ensuring food security. With the advancement of molecular biology, DNA sequencing, and recombinant DNA in the middle of the 20th century, modern-day advancement of molecular breeding gave rise to genetic engineering and recombinent DNA techniques that are today frequently connected to biotechnology. This expansion has been facilitated by a variety of fields, including genetics, molecular biology, and biotechnology. The use of genetic engineering in agriculture has grown due to its ability to precisely create and insert a gene from any living organism. Molecular markers are also utilized to identify disease and pest resistance in order to increase agricultural output using traditional techniques. Genetic engineering plays a crucial role in agriculture, representing the scientific and technical advancement of traditional methods for crop enhancement. Recombinant DNA technology, RNA interference, and CRISPR genomic editing are some of the instruments and methods used in genetic engineering. The emergence of biotechnological innovations aimed at improving the nutritional composition of individual foods has led to the growing problem of a malnourished world population, where a growing number of people rely on large regions of the world for food used as the only source of protein, carbohydrates, fats and several essential minerals and vitamins, in addition to being a source of energy.

Advances in Agricultural Biotechnology: Enhancing Productivity and Sustainability in India : A Review

Agricultural biotechnology has revolutionized farming practices in India, significantly enhancing productivity, sustainability, and socio-economic well-being. Here analyzes key advancements such as genetically modified (GM) crops, gene editing technologies, and biofertilizers, highlighting their impact on crop yields, pest and disease resistance, climate resilience, and environmental sustainability. The adoption of GM crops, particularly Bt cotton, has resulted in substantial yield improvements, reduced pesticide use, and increased farmer incomes, as evidenced by various case studies across different regions. Gene editing technologies like CRISPR offer precise genetic modifications, promising improvements in crop traits and resilience. Biofertilizers and biopesticides contribute to soil health and reduced chemical input use, promoting sustainable agricultural practices. The socio-economic benefits of biotechnology are evident in increased profitability for farmers, job creation in biotech sectors, and rural development through improved infrastructure and community-based initiatives. Challenges such as public perception, regulatory hurdles, and the need for robust training and capacity building remain. Addressing these challenges through transparent communication, updated regulatory frameworks, and continued investment in research and development is essential for realizing the full potential of agricultural biotechnology. The transformative impact of biotechnology on Indian agriculture, advocating for its integration into sustainable farming practices to ensure food security, environmental conservation, and economic growth. Biotechnological advancements, in India can enhance agricultural productivity, mitigate climate change impacts, and foster rural prosperity, ultimately contributing to the overall development of the agricultural sector.

Somatic Biotechnologies in the System of Social Values of Modern Russian Society

The paper is devoted to analyzing the impact of somatic biotechnologies on the system of social values of modern society. In the paper «somatic» refers to such technologies that relate to the genetic modification of the human body or its functional systems carried out in various ways. The authors attempt to analyze the main directions of transformation of social institutions of modern Russian society, taking into account advantages and disadvantages of the new technological revolution. Attention is drawn to the risks that biotechnologies pose to society and the state as a whole. The authors substantiate the necessity of participation of the state and various social groups in the development of an optimal strategy reflecting the interests of all stakeholders, based on transparency and trust. The paper indicates that it is necessary to determine the levels of permissible human exposure to various concomitant factors when using biotechnologies. This will require a normative rethinking of the entire concept of human and civil rights and freedoms enshrined in the Constitution of the Russian Federation that includes the right to life, its values, the principles of the inalienable fundamental human rights and freedoms, their belonging to everyone from birth, the right to privacy, the right to personal and family secrets, dignity and good name.It is important at the regulatory level to consolidate the legal regime of genetic data about a person in the system of social values, prohibit discrimination based on genetic uniqueness, and develop requirements for medical organizations using somatic biotechnologies. The resolution of future problems involves a theoretical rethinking and normative regulation of new forms of work that will appear in the future, as well as new types of property. The ideas of motherhood and childhood, as well as families, will require new content, which will affect the most important values of society and demand active involvement of the state.

The Future of Food.

The global food systems face significant challenges driven by population growth, climate change, geopolitical conflicts, crises, and evolving consumer preferences. Intending to address these challenges, optimizing food production, adopting sustainable practices, and developing technological advancements are essential while ensuring the safety and public acceptance of innovations. This review explores the complex aspects of the future of food, encompassing sustainable food production, food security, climate-resilient and digitalized food supply chain, alternative protein sources, food processing, and food technology, the impact of biotechnology, cultural diversity and culinary trends, consumer health and personalized nutrition, and food production within the circular bioeconomy. The article offers a holistic perspective on the evolving food industry characterized by innovation, adaptability, and a shared commitment to global food system resilience. Achieving sustainable, nutritious, and environmentally friendly food production in the future involves comprehensive changes in various aspects of the food supply chain, including innovative farming practices, evolving food processing technologies, and Industry 4.0 applications, as well as approaches that redefine how we consume food.

Adaptive resource-saving technologies in agriculture: The role of biotechnologies and their impact on environmental safety

The article examines the role of biotechnologies in agriculture and their impact on environmental safety. In the face of a growing population and changing climate conditions, it is important to develop adaptive technologies that promote resource conservation and reduce negative environmental impacts. Biotechnologies represent a powerful tool for creating such innovative solutions in agriculture. The article discusses various aspects of biotechnology application in agriculture, including increasing crop productivity, protecting plants from diseases and pests, and improving soil quality. Special attention is paid to environmental safety issues and comparative analysis of the impact of biotechnologies on the environment compared to traditional agricultural methods.

Promising Applications of Biotechnology: Boosting Health, Agriculture and Environmental Sustainability

The scientific paper explores the promising applications of biotechnology in three key areas: health, agriculture, and environmental sustainability. It highlights the crucial role of biotechnology in improving human health, ranging from advanced therapies to innovative drug discovery, offering new hope in the treatment of complex diseases. In addition, it examines the transformative impact of biotechnology on agriculture, presenting advances in genetically modified crops to increase productivity, resistance to pests and adverse climatic conditions, promoting global food security.
 The article also delves into the role of biotechnology in environmental sustainability, highlighting how biotechnology technologies are contributing significantly to the reduction of the ecological footprint through the development of biofuels, bioplastics, and bioremediation methods. Detailed analysis of these developments shows the transformative potential of biotechnology in improving the quality of human life, food security, and environmental preservation.

Millet's Role as a Climate Resilient Staple for Future Food Security: A Review

This review comprehensively examines the role of millets as a sustainable and resilient food source in the context of global climate change and escalating food security challenges. Millets, a group of small-seeded grasses traditionally grown in semi-arid regions of Africa and Asia, are re-emerging as crops of significance due to their remarkable adaptability to harsh environmental conditions and their rich nutritional profile. The review begins by outlining the various types of millets, including pearl, finger, and foxtail millet, and their geographic distribution, emphasizing their adaptability to diverse climatic conditions. It then delves into the nutritional aspects of millets, highlighting their high content of dietary fiber, vitamins, minerals, and essential amino acids, making them a potent solution to combat malnutrition and micronutrient deficiencies prevalent in many developing regions. A critical focus is placed on the climate resilience of millets. Their exceptional drought tolerance, ability to thrive in poor soil conditions, lower water, and nutrient requirements compared to staple crops like wheat and rice, and resistance to pests and diseases underscore millets' potential as sustainable crops in increasingly unpredictable climatic scenarios. This resilience not only promises to bolster food security but also contributes to sustainable agricultural practices. It explores the challenges and limitations in millet cultivation, processing, consumer acceptance, and market integration. It highlights the current gaps in millet-focused agricultural policies, the need for improved processing technologies, and strategies to enhance consumer appeal and marketability. Innovations in millet breeding for enhanced traits, advances in processing technologies, and the impact of biotechnology and climate-smart agricultural practices are examined. These technological and scientific advancements present opportunities for overcoming existing challenges and enhancing the role of millets in global food systems. Also presents case studies from various countries, particularly India, illustrating successful initiatives in millet cultivation, integration into national food policies, and community-led efforts. These examples offer valuable insights into practical approaches for promoting millets.

Philosophical & bioethical boundaries in current biotechnologies: human enhancement and welfare biology

The aim of this paper is to conduct a descriptive and normative exploration of the most intriguing current biotechnologies. Firstly, biotechnological means capable of enhancing humans will be described, including the possibility of transferring the mind to a non-biological device. Secondly, the emerging discipline of welfare biology will be explored, subjecting it to a theoretical stress test. Well-founded concerns regarding the potential impact of biotechnologies exist, with a particular emphasis on the speculative nature of mind uploading. In contrast to large-scale welfare biology, small-scale welfare biology seems entirely plausible to reduce wild animal suffering.

Metabolic engineering of Synechococcus elongatus 7942 for enhanced sucrose biosynthesis

Metabolic engineering of Synechococcus elongatus 7942 for enhanced sucrose biosynthesis

The Impact of Biotechnology on Mango Enhancement: Exploring Genetic Engineering and Molecular Markers

The impact of biotechnology on mango enhancement, particularly through genetic engineering and molecular markers, has been significant. Biotechnology has revolutionized the field of agriculture, offering innovative tools and techniques for improving crop traits. In the case of mangoes, genetic engineering involves the manipulation of the organism's DNA to introduce or modify specific genes, targeting traits such as disease resistance, fruit quality, and yield. This approach has led to the development of mango varieties with enhanced resistance to pests and diseases, improved flavour and aroma, and increased productivity. Similarly, marker-assisted selection (MAS) utilizes molecular markers to identify and select plants with desired traits, bypassing the need for time-consuming and costly phenotypic evaluations. MAS has accelerated breeding programs, enabling the development of superior mango cultivars with desired traits. By exploring the impact of genetic engineering and molecular markers in mango improvement, we gain insights into their potential to address key challenges in mango cultivation and meet consumer demands.

Marine Invertebrates: A Promissory Still Unexplored Source of Inhibitors of Biomedically Relevant Metallo Aminopeptidases Belonging to the M1 and M17 Families

Proteolytic enzymes, also known as peptidases, are critical in all living organisms. Peptidases control the cleavage, activation, turnover, and synthesis of proteins and regulate many biochemical and physiological processes. They are also involved in several pathophysiological processes. Among peptidases, aminopeptidases catalyze the cleavage of the N-terminal amino acids of proteins or peptide substrates. They are distributed in many phyla and play critical roles in physiology and pathophysiology. Many of them are metallopeptidases belonging to the M1 and M17 families, among others. Some, such as M1 aminopeptidases N and A, thyrotropin-releasing hormone-degrading ectoenzyme, and M17 leucyl aminopeptidase, are targets for the development of therapeutic agents for human diseases, including cancer, hypertension, central nervous system disorders, inflammation, immune system disorders, skin pathologies, and infectious diseases, such as malaria. The relevance of aminopeptidases has driven the search and identification of potent and selective inhibitors as major tools to control proteolysis with an impact in biochemistry, biotechnology, and biomedicine. The present contribution focuses on marine invertebrate biodiversity as an important and promising source of inhibitors of metalloaminopeptidases from M1 and M17 families, with foreseen biomedical applications in human diseases. The results reviewed in the present contribution support and encourage further studies with inhibitors isolated from marine invertebrates in different biomedical models associated with the activity of these families of exopeptidases.

Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability.

Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability.

How biotechnology could revolutionize the construction industry and green building project

The construction industry has been a vital contributor to the economy for many years. However, it is also known for being one of the biggest polluters, emitting a significant amount of carbon dioxide and consuming a vast amount of resources. Biotechnology is emerging as a promising solution to address the environmental impact of the construction industry. This abstract explores how biotechnology could revolutionize the construction industry and green building projects. It highlights the potential of biotechnology to reduce the environmental impact of construction through the use of sustainable materials and techniques. The study reviews the various biotechnology-based approaches that could improve the construction process, such as the use of genetically modified bacteria to produce bio-based materials and the use of biocatalysts to enhance the durability and strength of building materials. The study also examines the potential impact of biotechnology on the green building industry, with a focus on the development of energy-efficient and sustainable buildings. The study concludes that biotechnology has the potential to transform the construction industry by enabling the production of sustainable materials, enhancing the durability and strength of building materials, and improving the energy efficiency of buildings, ultimately contributing to a more sustainable and environmentally friendly built environment.

Complex Coacervate Materials as Artificial Cells.

Cells have evolved to be self-sustaining compartmentalized systems that consist of many thousands of biomolecules and metabolites interacting in complex cycles and reaction networks. Numerous subtle intricacies of these self-assembled structures are still largely unknown. The importance of liquid-liquid phase separation (both membraneless and membrane bound) is, however, recognized as playing an important role in achieving biological function that is controlled in time and space. Reconstituting biochemical reactions in vitro has been a success of the last decades, for example, establishment of the minimal set of enzymes and nutrients able to replicate cellular activities like the in vitro transcription translation of genes to proteins. Further than this though, artificial cell research has the aim of combining synthetic materials and nonliving macromolecules into ordered assemblies with the ability to carry out more complex and ambitious cell-like functions. These activities can provide insights into fundamental cell processes in simplified and idealized systems but could also have an applied impact in synthetic biology and biotechnology in the future. To date, strategies for the bottom-up fabrication of micrometer scale life-like artificial cells have included stabilized water-in-oil droplets, giant unilamellar vesicles (GUV's), hydrogels, and complex coacervates. Water-in-oil droplets are a valuable and easy to produce model system for studying cell-like processes; however, the lack of a crowded interior can limit these artificial cells in mimicking life more closely. Similarly membrane stabilized vesicles, such as GUV's, have the additional membrane feature of cells but still lack a macromolecularly crowded cytoplasm. Hydrogel-based artificial cells have a macromolecularly dense interior (although cross-linked) that better mimics cells, in addition to mechanical properties more similar to the viscoelasticity seen in cells but could be seen as being not dynamic in nature and limiting to the diffusion of biomolecules. On the other hand, liquid-liquid phase separated complex coacervates are an ideal platform for artificial cells as they can most accurately mimic the crowded, viscous, highly charged nature of the eukaryotic cytoplasm. Other important key features that researchers in the field target include stabilizing semipermeable membranes, compartmentalization, information transfer/communication, motility, and metabolism/growth. In this Account, we will briefly cover aspects of coacervation theory and then outline key cases of synthetic coacervate materials used as artificial cells (ranging from polypeptides, modified polysaccharides, polyacrylates, and polymethacrylates, and allyl polymers), finishing with envisioned opportunities and potential applications for coacervate artificial cells moving forward.

Influence of Cell Wall on Biomolecules Biosynthesis in Chlamydomonas reinhardtii Strains Exposed to Magnetic Fields

The application of magnetic fields (MF) has attracted the attention of researchers due to their efficiency to change cell metabolism. Chlamydomonas reinhardtii is a biotechnologically useful microalga with versatile metabolism that may be a valuable organism to study the effects of the MF in biology. Therefore, two C. reinhardtii strains, one with cell wall (2137) and other which lacks the cell wall (Wt-S1-cc4694), were evaluated that a new sensitivity factor in the analysis could be included. Comparative studies were undertaken with the two C. reinhardtii strains under the MF intensities of 0.005 mT (terrestrial MF - control), 11 and 20mT. Results indicated that the physical cell wall barrier protected cells against the MF applied during the assays. Only with the highest MF applied (20mT) a slight increase in lipid concentration in the cell wall strain was detected. The lowest growth of the strain that lacks cell wall (Wt-S1) indicated that these cells are under a negative effect. To cope with the two MF stresses conditions, Wt-S1 cells produced more pigments (chlorophylls and carotenoids) and lipids and enhanced the antioxidant defense system. The raise of these compounds under MF could potentially have a positive biotechnological impact on algal biomass.

Economic potential of biotechnologies: Challenges and windows of opportunity

Biotechnology is emerging as a transformative force with the potential to reshape industries and economies. This article delves into the economic potential of biotechnologies and explores the challenges and opportunities they present. The analysis is rooted in current global trends, innovations, and advancements in biotechnological research and applications. It also addresses the economic impact of biotechnology in various sectors, including healthcare, agriculture, energy, and the environment. The study highlights key challenges faced by biotech industries, such as regulatory hurdles, ethical concerns, and intellectual property issues, and proposes strategies to overcome these obstacles. Moreover, it identifies windows of opportunity for economic growth and sustainability through biotechnological innovations. The article concludes by emphasizing the need for strategic investment, interdisciplinary collaboration, and forward-thinking policies to unlock the full economic potential of biotechnologies and promote global prosperity.

The influence of biotechnologies, information and communication technologies on the formation of a healthy lifestyle among studentsу

This paper reflects the results of determining the impact of biotechnologies, information and communication technologies on the results in amateur and professional sports. The paper discusses the main issues of the impact of the achievements of biotechnology and information technology on the practice of sports, as well as their prevalence. Students involved both in groups of general physical training and in sports sections participated in the experiment. Among the participants of the study were both amateur athletes and athletes with sports categories and titles. The study was divided into areas: the prevalence and impact of sports trackers among athletes; biotechnological approach to monitoring and tracking the biological indicators of an athlete; systems for the formation of training programs based on the processing of biological indicators by neural networks. The main ways of using information and communication technologies and biotechnologies in sports were identified by studying current trends in amateur and professional approaches to playing sports: digital systems for fixing sports results, a biotechnological approach to monitoring and tracking an athlete’s biological indicators, systems for creating training programs based on processing biological indicators by neural networks. The influence of the combination of the above directions and factors on amateur and professional approaches to physical culture and sports is considered.