This research investigated the effects of drying methods (hot air or freeze drying) on the nutritional components and antioxidant activities of Eclipta prostrata (L.) L. leaf. The crude ash and crude protein contents of the freeze dried sample were higher than those of the hot air dried sample; however, the content of crude fat in the hot air dried sample was higher than that in the freeze dried sample. The contents of essential and non-essential amino acids were higher in the freeze dried sample than in the hot air dried sample. Total contents of organic acids in the freeze dried sample were higher than those in the hot air dried sample. Total saturated and unsaturated fatty acids were higher in the freeze dried sample than in the hot air dried sample. Total mineral contents in the freeze dried sample were higher than those in the hot air dried sample. The major minerals were K, Ca and Mg in the two different drying methods. The contents of vitamin C and E in the freeze dried sample were higher than those in the hot air dried sample. The total polyphenol and total flavonoid contents in the freeze dried sample were higher than those in the hot air dried sample. The IC50 value of Eclipta prostrata (L.) L. leaf in the hot air or freeze drying methods in the ABTS+ assay was 0.77 mg/mL and 0.69 mg/mL, respectively. These results showed that the two different drying methods affected the nutrient contents and antioxidant activities of the Eclipta prostrata (L.) L. Therefore, we suggest that freeze drying is an effective method for manufacturing high-quality Eclipta prostrata (L.) L leaf.
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