History Of Infectious Diseases Research Articles

Faktor-Faktor yang Berhubungan dengan Kejadian ISPA pada Balita

ISPA is an infectious disease of the upper and lower respiratory tract which is caused by the entry of microorganisms (bacteria and viruses) into the respiratory tract organs which lasts for 14 days. This study aims to determine the relationship between ventilation, type of house floor, type of fuel. for cooking, completeness of immunization and history of infectious disease against the incidence of ARI in children under five. This type of research is quantitative, using the analytical survey method with a cross-sectional approach. The research location is in the working area of the Alang-Alang Lebar Community Health Center in Palembang City with a total of 78 respondents. The primary data source was obtained by means of a questionnaire and secondary data was obtained from the profile and records of the Alang-Alang Lebar Community Health Center Palembang. Data analysis consisted of univariate and bivariate analysis using the chi square test. The results of the chi square test showed that the variables associated with the incidence of ARI in children under five were ventilation (p = 0.000 ≤ 0.05), and a history of infectious diseases (p = 0.039 ≤ 0.05). Based on the results of the study and discussion, it was concluded that there was a simultaneous relationship between ventilation and a history of infectious diseases simultaneously with the incidence of ARI in children under five in the Alang-alang Lebar Community Health Center Palembang City in 2020.

James L. A. Webb, The Guts of the Matter. A Global History of Human Waste and Infectious Intestinal Disease. (Studies in Environment and History.) Cambridge, Cambridge University Press 2020

Article James L. A. Webb, The Guts of the Matter. A Global History of Human Waste and Infectious Intestinal Disease. (Studies in Environment and History.) Cambridge, Cambridge University Press 2020 was published on February 1, 2021 in the journal Historische Zeitschrift (volume 312, issue 1).

Hygiene, Morality and the Pre-Criminal: Genealogies of Suspicion from Twentieth Century British-Occupied Egypt

The concept of the ‘pre-criminal space’ has seen increasing uncritical use in countering terrorism policy since 9/11. It is understood by critical scholars primarily as a new legal temporality that brings forward the ‘threshold of criminal responsibility’, thus allowing for pre-emptive, suspicion-based criminalisation. This has allowed for the validation of measures such as arbitrary arrest and detention, bogus trial and restrictions on liberty, and is evidenced as being applied in an Islamophobic and racialised manner to entire communities. Furthermore, in our contemporary moment of Covid-19 where the emergency tools used to regulate hygiene and infection intersect with those used in countering terrorism work, critics are increasingly concerned about the expansion and normalisation of the pre-criminal space and its use in pathologising and medicalised ways. Using archival research, this article adapts the contemporary concept of the ‘pre-criminal’ to a historical and medico-legal context. In doing so it traces how the history of infectious diseases – in particular VD – has shaped the space through slippages between hegemonic understandings of morality, hygiene, vagrancy and extremism. I show how the ‘vagrant’ nature of disease marked racialised, gendered and classed subjects as potentially infectious and immoral. Looking particularly at the regulation of sex workers in British-occupied Egypt, I conceptualise the power struggles between actors including the British administration, British abolitionist feminists and the Egyptian government as a securitisation network which infiltrated the lives of Egyptians and marked them as suspicious. I further show how the encroachment upon everyday lives was made even more possible through the implementation of martial law. In this way, I suggest that contemporary British forms of pre-criminality and risk can be understood as a latent form of coloniality present in law-making practices.

The Guts of the Matter: A Global History of Human Waste and Infectious Intestinal Disease by James L. A. Webb Jr

The Guts of the Matter: A Global History of Human Waste and Infectious Intestinal Disease by James L. A. Webb Jr

전염병 위기와 방역시스템 인식 분석 및 대응 방안

Human history can also be said to be the history of fighting against viruses. Worldwide, about 290,000 or 640,000 people die each year from influenza-related respiratory diseases. Diseases and calamities caused by viruses have so far been very close to humanity, so understanding the causes and mechanisms of viruses helps us strengthen preparedness and respond scientifically. In this context, the purpose of this study is to analyze the impact of infectious diseases in history on human society and the role they play on the quarantine system, and to find the right response and quarantine system for the sustainable survival of mankind in the face of an ever-increasing infectious disease crisis. and presents an alternative. On the other hand, it is to analyze the perception of the infectious disease crisis and the quarantine system, and to provide opinions on how to respond to the infectious disease crisis and develop the quarantine system. Therefore, this study emphasized the importance of developing the quarantine system and improving awareness of crisis by analyzing various behavioral and psychological states after the outbreak of COVID-19, from human efforts to eradicate the virus to the development of the quarantine system. They also discussed how to deal with an infectious disease crisis. For this purpose, a graph analysis method was used. The graph analysis method was used to compare and analyze the quantitative change and regularity of social phenomena in various fields by representing the situation of social phenomena in the form of statistical graphs.

Hubungan antara Frekuensi dan Durasi Diare dengan Kejadian Stunting pada Balita Usia 24-36 Bulan di Desa Kedungrejo Kecamatan Pakis

Stunting is a condition where there a disruption of growth in body length or height that not by age. A history of infectious diseases are one of the direct factors that can cause this condition. Diarrhea is an infectious disease which if occurs continuously can cause a significant decrease in fluid levels in the body, causing interference in the absorption of nutrients. This study aimed to analyze the relationship between the frequency and duration of diarrhea with the incidence of stunting in children aged 24-36 months. The study used a case control design with the subjects of the case group was stunting toddlers with their mother while the control group was non-stunting toddlers with their mother in Kedungrejo village, District of Pakis with a total of 24 for each group. Data was collected by anthropometric measurements in toddlers and mothers were interviewed using a diarrhea history questionnaire that had been tested for validity and reliability. The bivariate analysis used Chi-Square test. The results showed that from of 48 subjects, the percentage of toddlers aged 24-36 months who had a history of frequent diarrhea frequency was 14,5% (7 children) and the percentage of toddlers who had a mean duration of long diarrhea was 33,3% (16 children). Statistical test results showed that frequency of diarrhea was not significantly related (p = 1,000) but increased the risk of stunting by 1,4 times, while the duration of diarrhea was significantly related (p = 0,030) and increased the risk of stunting by 5,0 times. It can be suggested that counseling is needed to provide information to the public about the first aid of diarrhea in toddlers as to minimize delays in treatment and reduce the risk of stunting.

Designing the Next Generation of Vaccines: Relevance for Future Pandemics.

ABSTRACTThe development of vaccines is one of the greatest medical interventions in the history of global infectious diseases and has contributed to the annual saving of at least 2 to 3 million lives worldwide. However, many diseases are not preventable through currently available vaccines, and the potential of modulating the immune response during vaccination has not been fully exploited. The first golden age of vaccines was based on the germ theory and the use of live, attenuated, inactivated pathogens or toxins. New strategies and formulations (e.g., adjuvants) with an immunomodulatory capacity to enhance the protective qualities and duration of vaccines have been incompletely exploited. These strategies can prevent disease and improve protection against infectious diseases, modulate the course of some noncommunicable diseases, and increase the immune responses of patients at a high risk of infection, such as the elderly or immunocompromised patients. In this minireview, we focus on how metabolic and epigenetic modulators can amplify and enhance the function of immunity in a given vaccine. We propose the term “amplifier” for such additives, and we pose that future vaccines will have three components: antigen, adjuvant, and amplifier.

Someday a Big Plague Will Come: Laurie Garrett’sThe Coming Plague: Newly Emerging Diseases in a World out of Balance

Someday a Big Plague Will Come: Laurie Garrett’sThe Coming Plague: Newly Emerging Diseases in a World out of Balance

Viral Vampires

Viral Vampires

Determinants of Anemia among Early Adolescent Girls in Kendari City

Background: Adolescent girls' anemia is a public health challenge. Anemia has an impact on cognitive abilities to reduce intelligence and results in adolescent achievement is down.Objective: The purpose of this study was to analyze the determinants of anemia in early adolescent girls in Kendari City.Methods: This study used a cross-sectional design with a sample of 97 students. Data on parental characteristics, breakfast habits, nutritional status, menstrual status, and history of infectious diseases were collected by interview using a questionnaire. Data on nutrient intake (iron, protein, vitamin C) obtained through the 2x24 hour recall method then compared to the Indonesian standard (AKG). Hemoglobin level was measured using the EasyTouch heamoglobin meter device. Data analysis was done by chi-square analysis and multiple logistic regression analysis.Results: The results showed 28.9% of adolescent girls had anemia. The results of chi-square analysis obtained that there was a relationship between the incidence of anemia on mother's education (p=0.010,), parental income (p=0.017), iron intake (p=0,000), protein intake (p=0,000), vitamin C intake (p=0.023), breakfast habits (p=0.006), menstrual status (p=0.007) and history of infection diseases (p=0,000). While the results of multiple logistic regression analysis obtained that there was a relationship between iron intake (p=0.005,OR=3.009), protein intake (p=0.007,OR=2.012), vitamin C intake (p=0.038,OR=1.167), menstrual status (p=0.002,OR=3.181) with anemia.Conclusion: The dominant determinant of anemia in early adolescent girls in Kendari City is menstrual status. It is recommended to intervene in risk factors (mother's education, parental income, iron intake, protein, vitamin C, breakfast habits, menstrual status and history of infectious disease) to reduce the prevalence of anemia among adolescent girls.

감염병의 법과 역사

감염이란 다른 사람에게 옮기는 것이다. 다른 사람이 없는 곳에 감염의 문제가 생기지 않는다. 따라서 다른 사람이 많으면 많을수록, 감염이 생기기 쉬워진다. 그렇기 때문에 도시라고 하는 사람의 유통이 격렬하고, 집중하는 장소에서, 감염의 문제가 논의되어 왔다. 본론은 이들 시각이 섞이면서, 17세기 말부터 19세기의 끝에 이르기까지 파리 안에서 어떠한 관념을 생성하고, 그것이 어떻게 법적으로 말해졌는지에 대해 역사적으로 논하는 시도였다.<BR> 우리가 지금까지 본 것은 도시에 생긴 감염문제가 사람들에게 사로잡힌 행동의 역사이다. 주변화, 격리, 위생 등이다. 죽음을 피하는 것에 삶을 증진시키는 것이 점차 덧붙여져 간 역사이다. 그것은 인간의 신체를 주변화하고 격리하는 것에 도시라는 공간을 관리하고 그 조건에 작용하는 것이 부가된 역사이다. 신체에 작용하는 것이 점차 인구나 사회에 작용하는 것으로 바뀌어 사회의 건강을 지키고 증진시키는 관점으로 바뀌어 간 역사였다.<BR> 병이라고 하는 관점에서 본다면, 개인의 것이었던 병은 점차 사회의 것으로 바뀐다. 그러한 관점에서 개인과 사회의 관계는 역전된다. 사회가 병에 걸리지 않도록 각 개인이 위생에 대한 의무를 져야 한다. 그것은 루소적인 세계이지만, 그 사회계약은 자발적인 것은 아니다. 연대주의는 태어날 때부터 귀속하는 사회에 대해서도 가지 않으면 안 되는 의무관계로서 위생법을 성립시켰던 것이다. 부르주아에 따르면 사회 연대의 위치는 경제 자유방임주의와 집단주의라는 상대되는 이론의 중간에 존재한다. 그 사이에서 맡은 역할은 자유를 배제하기는커녕 자유가 진정한 의미로 존중되고 효과적으로 발전시키는 것이다. 따라서 연대라는 관념은 자선이나 박애에 가깝고 도덕과 권리와의 관계에서 정의, 평등, 소유의 관념에 영향을 주게 된다.<BR> “사회에 사는 인간들은, 서로의 사이에 서로의 의무를 낳는다. 그 의무는 인간을 독립하고 고립된 존재라고 하며, 그 범위로만 한정하는 입장보다, 보다 넓고 복잡하다.” 사회평화를 위해서 필요한 형평의 규칙은 임의나 강제를 불문하고 조력의 끊임없는 교환을 촉진하는 것이며, 그 조력은 사회적인 의무이다. 각자는 모두에게, 사회적 부채를 가지고 있다. 그 의무나 부채는 정의라는 원리에 기초를 두고 있다.

Bacterial colonization of explanted non-endocarditis cardiac valves: evidence and characterization of the valvular microbiome.

Bacterial colonization has been already demonstrated in heart valve tissues of patients without cardiovascular infections. However, the evidence of a valvular microbiome is still scarce. The next-generation sequencing method was carried out on 34 specimens of aortic (n = 20) and mitral valves (n = 14) explanted from 34 patients having neither evidence nor history of infectious diseases, particularly infective endocarditis. While no bacteria were demonstrated using standard culture methods, bacterial deoxyribonucleic acid (DNA) sequences were found using next-generation sequencing in 15/34 (44%) cases. Escherichia coli was present in 6 specimens and was the most frequently identified bacterium. There was a trend towards a higher rate of bacterial DNA positivity in specimens of calcific valves than in those of non-calcific valves (10/17 vs 5/17, P = 0.17). Based on a quantitative test, E. coli accounted for 0.7% ± 1% in calcific valvular tissue and 0.3% ± 0.3% in non-calcific valvular tissue (P = 0.2), and for 11% ± 27% in the valvular tissue of diabetic patients and 0.3% ± 1% in the valvular tissue of non-diabetic patients (P = 0.08). Detection of bacterial DNA in non-endocarditis valvular tissues could be a relatively common finding. There could be an association between the valvular microbiome and certain models of valve degeneration and common metabolic disorders.

THE MATERNAL, SANITATION, CHILD’S INFECTIOUS DISEASE HISTORY AND DIARRHEA AMONG UNDER 5 AGE CHILDREN IN SAMPANG

Diarrhea is the second leading cause of children death in the world after pneumonia. The case managements have been increased and developed but the mortality rate due to diarrhea is still high. Sub-Saharan Africa and Southeast Asia were known as the highest case regions of diarrhea, including Indonesia as part of the developing countries. The purpose of this study was to analyze the relationship between maternal factors, sanitation, and a history of childhood infectious diseases with the incidence of diarrhea in Sampang. The research used a cross-sectional design study with a total sampling technique. The source data was from Riskesdas 2018 by Indonesian Health Ministry and analyzed by univariate, bivariate, and multivariate. The result of multivariable logistic regression analysis showed that maternal factors: handwashing behavior (OR 4.687; 95% CI 0.473-46.469); education level (OR 1.815; 95% CI 0.108-1177), waste management (OR 4.333; 95% CI 0.509-36.011) and a history of infectious disease in children (OR 5.421; 95% CI 1.444 -20.354).

Covid-19 Transmission Dynamics During the Unlock Phase and Significance of Testing

The pandemic disease Covid-19 caused by SARS-COV-2 has established itself as the most devastating disease in the history of infectious disease, affecting 216 countries/territories across the globe. Policies like social distancing and lockdown were adopted to tackle the spreading of the disease. The disease is still not under control, but many countries have withdrawn the lockdown and going through phase-wise unlock-ing process. The removal of movement restriction causes free circulation of the disease mostly through the undetected class. The present study is an attempt to understand and estimate the possible epidemic burden during the unlock phase in the presence of the undetected class. Through a modified SEIR model, we focus our study on India and the USA, where the epidemic curve is still growing and the unlock process has started. We estimated the parameter values for both the countries using available data and used them to calculate the basic reproduction number. We also performed a global sensitivity analysis to search for the most sensitive parameters which can significantly change the dynamics of the disease. We observed that the use of repurposing drugs may further decrease the infected cases and help the disease controlling process. Our results emphasize on the implementation of 3T principles, trace, test, and treat, to contain the epidemic. The significance of large-scale testing in restricting the spread of infection during the unlock phase is evident for both India and the USA though they have different socio-economic conditions.

Postnatal Factors Associated With The Risk Of Stunting In Toddlers

The design of this study uses observational analytical research with case control design. A sample of 450 toddlers was selected using fixed disease sampling which included a case group of 150 toddlers with stunting and a control group of 300 normal toddlers who were not in stunting, wasting and overweight conditions. The data collection tool uses questionnaires and data processing using double logistic regression analysis. Stunting is influenced by the length of the birth body (OR=3.14; CI 95%=2.42 to 3.86; p=&lt;0.0001), breastfeeding (OR=2.31; CI 95%=1.69 to 2.93; p=&lt;0.0001) and history of infectious diseases (OR=2.26; CI 95%=1.61 to 2.91; p=&lt;0.0001). Birth weight has no effect on stunting events (OR=1; CI 95%=0.32 to 1.68; p=0.004). The incidence of stunting increases with less birth length, unsy exclusive breastfeeding and the absence of a history of infectious diseases in toddlers

Immunological Aspects of Chytridiomycosis

Amphibians are currently the most threatened vertebrate class, with the disease chytridiomycosis being a major contributor to their global declines. Chytridiomycosis is a frequently fatal skin disease caused by the fungal pathogens Batrachochytrium dendrobatidis (Bd) and Batrachochytrium salamandrivorans (Bsal). The severity and extent of the impact of the infection caused by these pathogens across modern Amphibia are unprecedented in the history of vertebrate infectious diseases. The immune system of amphibians is thought to be largely similar to that of other jawed vertebrates, such as mammals. However, amphibian hosts are both ectothermic and water-dependent, which are characteristics favouring fungal proliferation. Although amphibians possess robust constitutive host defences, Bd/Bsal replicate within host cells once these defences have been breached. Intracellular fungal localisation may contribute to evasion of the induced innate immune response. Increasing evidence suggests that once the innate defences are surpassed, fungal virulence factors suppress the targeted adaptive immune responses whilst promoting an ineffectual inflammatory cascade, resulting in immunopathology and systemic metabolic disruption. Thus, although infections are contained within the integument, crucial homeostatic processes become compromised, leading to mortality. In this paper, we present an integrated synthesis of amphibian post-metamorphic immunological responses and the corresponding outcomes of infection with Bd, focusing on recent developments within the field and highlighting future directions.

Determinants Factors Affecting Stunting In Children 2-5 Years In The Working Area Of Tajinan Public Health Center

Background: Malang Regency is included in the 100 priority districts for stunting with a stunting rate of 20% spread over 6 priority villages.Objective: The research was to analyze risk factors related to child, mother, and environmental factors for stunting under five years old.Method : The study used a case-control design population was all children aged 2 to 5 years at the Tajinan Public Health Center for six months in 2018. The case sample was 75 stunting toddlers and the control was 75 toddlers well-nourished. Data was collected by interview and measurement (anthropometry). Data was analyzed by chi square test and multiple logistic regression.Result : 80% of stunted children had infectious diseases, a history of length of birth 48 centimeters and low birth weight was 72% and 10%, a history of breastfeeding and complementary foods (59%). The risk factors for stunting were a history of low birth weight, a history of infectious diseases, maternal education, environment sanitation, and family income.Conclusion : The most influential factors are history of infectious diseases and environment sanitation. It is necessary to increase family empowerment related to the prevention of infectious diseases through improving dietary and health care patterns and improving environment sanitation.

Risk Factors of Type 1 Diabetes Mellitus in Children Attending Aswan University Hospital

Background: Type 1 diabetes (T1DM) is a chronic disease caused by immune-mediated destruction of insulin producing beta cells in the pancreas. The destruction of beta cells results in insulin insufficiency, and patients develop life-threatening hyperglycemia that clinically manifests with weight loss, polyuria, and polydipsia. Objective: This study aimed to search for disease prediction and disease prevention. Patients and methods: The present cross-sectional study was conducted at Aswan University Hospital. One hundred children with T1DM were included during the period from April to November 2018. The mean age of the included patients was 7.2 ± 4.3 years and the age at onset of the disease was 4.56 ± 2.9 years. 56% of the patients were males. Results: In our cohort, we found that, in terms of obstetric history, 76% of the mothers delivered by CS and 12% of them had history of preeclampsia. 13% had a history of gestational diabetes. On the other hand, 13% and 29% of the mothers had a history of infectious diseases and use of antibiotics, respectively. There were no statistically significant associations between age group and preeclampsia (p =0.33), gestational diabetes and use of insulin (p =0.67), infectious diseases (p =0.91), use of antibiotic (p =0.26), use of antihypertensives (p =0.22), and mode of delivery (p =0.067). Conclusion: In conclusion, Egyptian children with T1DM had wide range of genetics, environmental, maternal, and neonatal risk factors that may have contributed to the development of T1DM.

Highly Infectious Diseases in Critical Care: A Comprehensive Clinical Guide

In the seventh century, the prophet of Islam, Muhammad, said “If you hear of plague (outbreak) in a land, do not enter it; and if the plague (outbreak) occurs in a land while you are in it, do not leave it,” and in 2015, Bill Gates said “If anything kills over 10 million people in the next few decades, it’s most likely to be a highly infectious virus. We’re not ready for the next epidemic.” Throughout history, the world has been hit by numerous epidemics that caused lots of losses and sufferings. Today, in the time of the coronavirus disease 2019 (COVID-19) pandemic, it became crucial for all health care practitioners to expand their knowledge of infectious diseases. Jorge Hidalgo, a Critical Care specialist from Belize, and Laila Woc-Colburn, a Tropical Medicine specialist from the United States, have edited a new book, Highly Infectious Diseases in Critical Care: A Comprehensive Clinical Guide, intended primarily, but not exclusively, for critical care providers. Each of the editors has a significant research expertise in the field of infectious diseases. A group of international experts in infectious diseases, internal medicine, critical care, emergency medicine, anesthesiology, and microbiology have contributed to writing its various chapters. The book discusses the epidemiological and microbiological aspects of the commonly encountered infectious diseases, discusses the diagnostic and therapeutic strategies focusing on critical care management, and describes the steps for an intensive care unit (ICU) to prepare for infectious diseases and epidemics. It is unique in being written from critical care perspective and is available in printed (hardcover) and electronic (PDF) versions. The book comprises 16 properly ordered chapters. The first 3 chapters provide general information about the history, epidemiology, and microbiology of infectious diseases and emphasize the role of various community facilities and health care systems involved in the management of outbreaks. The fourth chapter discusses the laboratory methods of diagnosing viral, bacterial, fungal, and parasitic infections. The following chapters comprehensively discuss the epidemiology, microbiology, diagnosis, and management of the most prevalent and hazardous infectious diseases, including respiratory viral infections (influenza, measles, coronavirus, and smallpox), zoonotic infections (anthrax, plague, and tularemia), viral hemorrhagic fevers (Ebola virus, Marburg virus, Crimean-Congo fever, Lassa fever, and yellow fever), multidrug-resistant bacteria (Enterococcus, Staphylococcus aureus, and Enterobacteriaceae), rabies, tetanus, malaria, and tuberculosis. In addition, 2 chapters discuss the pathogenesis and management of various central nervous system infections and the monitoring and management of intracranial pressure in patients with bacterial meningitis. The book concludes with 2 essential chapters describing how to plan and prepare an ICU for a highly infectious disease and how to declare and prepare for a pandemic. In general, the book provides a balanced combination between the basic epidemiological and microbiological knowledge and the clinical diagnostic and therapeutic applications. In addition, it provides valuable historical and cultural information and incorporates a number of important concepts, such as antibiotic resistance, biowarfare, and management in resource-limited settings. The sections of each chapter are neatly ordered and properly discussed, the presented figures and illustrations are informative, and the references are appropriate and adequate. The authors use an interesting, systematic style and a scientific, yet easy language. We have a number of comments. When discussing the history of previous epidemics, little information is provided about the important Spanish flu and cholera epidemics. An illustration summarizing the roles of different health care units in the triage of highly infectious diseases and in the setting of a suspected bioterrorism attack may be added to Chapter 3. In Chapter 4, the names of the authors are unnecessarily written after some subheadings. In Chapter 5, various viral infections (influenza, measles, coronavirus, and smallpox) are collectively discussed under each subheading (Biology, Epidemiology, Clinical Findings, Diagnosis, and Management). The different infections might have better been discussed separately in a systematic manner. Chapter 14 might have been entitled “Multidrug-Resistant Tuberculosis” rather than “Tuberculosis Multidrug Resistance.” Finally, in our opinion, Chapters 10 and 15 contain parts that are difficult to understand and need linguistic revision. In conclusion, Highly Infectious Diseases in Critical Care: A Comprehensive Clinical Guide is an excellent, concise resource that provides valuable information about the epidemiology, pathogenesis, and management of various infectious diseases and helps critical care practitioners to manage the current pandemic and to be “ready for the next epidemic.” Mohamed Mohamed Tawfik, MDAmal Ahmed Nour, MScDepartment of Anesthesia and Surgical Critical CareMansoura University HospitalsMansoura, Egypt[email protected]

Kejadian Wasting pada Balita Usia 6-59 Bulan

Wasting is an acute malnutrition which could indirectly increase infant mortality and morbidity. Currently, wasting was serious public health problem in Indonesia with 11,1% of prevalence. This study aimed to determine the incidence of wasting in childrens aged 6-59 months in the working area of Puskesmas Kelurahan Penjaringan I, North Jakarta from March to April, 2019. The researcher measured antropometry of children to see nutritional status based on indicator of BB/TB. A case control method, as well as purposive and accidental sampling technique, was carried out in this study. As many as 60 respondents were divided into 2 groups (30 cases group and 30 control group). The data were analyzed by using chi square test and multiple logistic regression. Infectious disease history (p=0.031) and protein intake (p=0.024) were associated with wasting incidence in children. Infectious diseases history was dominant factor determining of wasting in children aged 6-59 months in Puskesmas Kelurahan Penjaringan I, North Jakarta (OR=11.897; 95% CI=1.246-113.570). Fostering integrated health post by providing counseling about increasing nutrient intake especially protein intake and handling infectious diseases in children so that wasting can be handled properly.