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  • New
  • Research Article
  • 10.1007/s11332-026-01664-2
Long COVID and physical function in the scientific literature: a bibliometric analysis in Scopus and Web of Science
  • Feb 6, 2026
  • Sport Sciences for Health
  • Ángel Denche-Zamorano + 5 more

Abstract Background It is estimated that following acute SARS-CoV-2 infection, about 10% of people experience persistent symptoms lasting more than 3 to 4 weeks, a condition known as long COVID syndrome. Amongst its various sequelae is impairment of physical function or functional ability. Given the growing social impact of this condition, the dissemination of knowledge in this area is essential. Bibliometric analysis provides valuable information on research trends and hotspots, helping to guide future studies and inform evidence-based interventions. Aims The aim of this study was to conduct a bibliometric analysis of research on long COVID syndrome and Physical Function. Method A total of 213 single documents indexed in the Scopus (205) and WOS core collection (181) database were analysed using the traditional laws of bibliometrics. Results It was found that annual publications have experienced exponential growth from 2020 to 2024, based on the data available at the time of the bibliographic search. Amongst the prolific authors, four production clusters were found, with Eleuterio A. Sánchez-Romero emerging as the most productive author. Spain and Brazil were the countries with the highest number of publications. The journals of the MDPI publishing house contributed the most papers to the object of study, especially the Journal of Clinical Medicine and the International Journal of Environmental Research and Public Health. Rehabilitation, fatigue, quality of life, and exercise were four of the main keywords used by the authors. Conclusions The observed growth in publications suggests increasing research attention to long COVID syndrome and physical function; however, further research is still needed to establish physical function assessment protocols, patient profiles, and effective exercise-based rehabilitation programmes.

  • New
  • Research Article
  • 10.1093/milmed/usaf647
Military Exposures Research: A State-of-the-Art Review.
  • Jan 31, 2026
  • Military medicine
  • Rachel T Wright + 7 more

Military personnel encounter a wide range of environmental and occupational exposures during their service such as burn pit smoke, chemical warfare agents, depleted uranium, jet fuel, radiation, and pesticides. The field of military exposures research seeks to better understand the nature of these exposures and their effects on Veteran and service member health. This state-of-the-art review assesses the breadth and depth of published military exposures research so that stakeholders can identify trends and gaps in this growing field. An evidence mapping approach was used to perform a literature review of military exposures research published from 1962 to 2024. The search strategy was developed around exposed cohorts: groups of military personnel with a shared potential for exposure to toxic agents. Publications were included if they directly addressed exposures or related health outcomes in military cohorts. Publications were then further categorized by the type of research, and the results were analyzed to build a map of the current military exposures research landscape. Thirty-six exposed cohorts were identified in the literature which were then grouped based on the nature of the exposure event: Wars and Operations (4 cohorts), Occupational Exposures (5), Combat and Combat Training (2), Across Military (2), Ship Exposures (2), Defense Testing (2), Base/Garrison Exposures (9), Toxic Substance Clean-Up and Disposal (5), and Isolated Exposure Events (5). The search identified 2,321 publications that fit the review inclusion criteria. The exposed cohort with the highest number of publications was Gulf War (940, 40.5% of all publications) followed by Vietnam War (277, 11.9%), Post-9/11 Operations in Iraq and Afghanistan (191, 8.2%), Aircraft Mechanics and Ground Support (176, 7.6%), and Munition Emissions and Embedded Fragments (164, 7.1%). Each remaining cohort individually represented < 4% of the literature. Six cohorts appeared only in non-peer-reviewed reports. The type of research best represented was Epidemiology (34.0%) followed by Animal and In Vitro Models (18.8%), Sequelae and Management (17.1%), Reviews and Meta-Analyses (11.7%), Exposure Assessment (9.5%), Toxic Agent Sampling and Analysis (4.3%), and publications from the National Academy of Sciences, Engineering, and Medicine (4.6%). The volume of military exposures research has increased steadily since the early public reports of Gulf War Illness in 1994, with 50% of articles being published after 2008. Military exposures research published since 1962 has focused on cohorts from large, high-profile deployments, particularly the Gulf War. Underrepresented cohorts with potential exposures on bases or from military occupations present opportunities for future research. The lack of meaningful exposure assessment data that has been published also points to further research opportunities to specifically improve collection and accessibility of exposure data. This work should be done with a focus on cohorts where research can directly impact Veterans access to benefits and exposure-informed care.

  • New
  • Research Article
  • 10.1002/pits.70141
Mental Health Literacy in Schools: A Bibliometric Analysis
  • Jan 16, 2026
  • Psychology in the Schools
  • Kızbes Meral Kılıç

ABSTRACT The aim of this study is to examine research on mental health literacy in schools from a macroscopic perspective, evaluate the quantity and quality of the studies and identify the gaps in the relevant literature. In this study, studies published in the Web of Science database on mental health literacy in schools until March 1, 2025 were subjected to bibliometric analysis using the Biblioshiny interface in the Bibliometrix R Package and VOSviewer. A total of 604 articles on mental health literacy in schools were analysed from 274 sources published between 2003 and 2025. The most prolific journals were BMC Public Health, International Journal of Environmental Research and Public Health and Early Intervention in Psychiatry. According to Bradford′s Law analysis, out of 274 productive journals, 20 were in the first, 67 in the second and 187 in the third region. According to Lotka′s Law, 86% of the authors published one article, 10% published two articles and 0.2% published three articles. The most commonly used keywords in studies on mental health literacy in schools were disorders, attitudes, beliefs, depression, knowledge, help‐seeking, stigma, illness, literacy, and prevelence. In recent years, terms such as scale, programs, perceived stigma, questionnaire, and quality have attracted particular attention. It was observed that the countries with the highest number of publications were the USA, Australia and Canada, and the countries with the highest number of collaborations were the USA‐United Kingdom, Canada‐ United Kingdom and USA‐Australia. This study aims to provide a global perspective on mental health literacy in schools.

  • New
  • Research Article
  • 10.1007/s44217-025-01085-2
A systematic review of MOOC platforms, evaluation frameworks and development of integrated model
  • Jan 16, 2026
  • Discover Education
  • Shahid Maqbool Mir + 1 more

Abstract Purpose The study aims to systematically evaluate studies focused on the evaluation of Massive Open Online Course (MOOC) platforms and existing frameworks to evolve an integrated model for the comprehensive evaluation of MOOC platforms. Design/methodology/approach The study follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and the Web of Science (WoS) database was used to retrieve the data. A thematic analysis method was used to critically examine the existing frameworks identified in different studies to identify different criteria concerning various aspects of MOOC platforms. The identified criteria were further analysed to include different components concerning different aspects of MOOC platforms to propose a theoretically grounded integrated evaluation framework for MOOC platforms. Findings The findings highlight a diverse set of evaluation frameworks used in MOOC research, including Kirkpatrick’s Model, Quality Matters (QM) Evaluation Framework, and Web Content Accessibility Guidelines (WCAG). After critical analysis and discussion among peers, the study identified six major evaluation dimensions: course design and structure, learner engagement, instructional quality, assessment and learning outcomes, technical and administrative factors, and demographic and completion metrics. Furthermore, the results reveal that most MOOC research is concentrated in China, the UK and the US. Additionally, most studies employed quantitative and mixed-method approaches, with surveys being the most commonly used data-collection tool. Furthermore, xMOOC is a commonly studied platform, and the highest number of publications were published in 2024. Originality/value The study offers a unique integrated framework by synthesizing existing MOOC evaluation frameworks, providing a practical tool for the consistent and comprehensive assessment of MOOC platforms.

  • Research Article
  • 10.1007/s00405-025-09964-y
Latest research hot spots of tympanostomy tube: A bibliometric analysis and visualized review.
  • Jan 6, 2026
  • European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • Bassam Alrajhi + 8 more

Tympanostomy tubes (TTs) are commonly used to treat chronic otitis media and recurrent ear infections, improving hearing and reducing effusions. This bibliometric analysis aimed to explore research trends and emerging topics in TT studies. A bibliometric analysis was conducted using the Web of Science Core Collection (WoSCC), focusing on English-language studies published between 2000 and 2024. After screening, 644 articles were included in the study. VOSviewer was used to analyze the data and generate visualizations of publication trends, top countries, institutions, journals, and citations. Our analysis revealed 644 relevant publications. The United States led in terms of both publications (287) and citations (4,385). The University of Pittsburgh had the highest number of publications, whereas Johns Hopkins University had the highest number of citations per publication. Furthermore, Finland demonstrated an exceptional impact, with the highest citation-per-publication (CPP) value of 29.11, followed by Denmark (27.33) and Canada (21.41). Acta Oto-Laryngologica was the most productive journal. The key author was Richard M. Rosenfeld. U.S. Government agencies provided most of the funding. Keyword analysis identified otitis media, tympanostomy tubes, and Eustachian tube dysfunction as central themes, with emerging research on middle ear ventilation and surgical techniques. This study highlights the influential role of North America (U.S and Canada) and Europe (England, Finland, and Denmark) in TT research, with key institutions and authors shaping the field. Emerging areas of focus include middle ear ventilation and the use of advanced surgical techniques.

  • Research Article
  • 10.1186/s43166-025-00368-8
A bibliometric analysis of research on fibromyalgia and physical function based on the Web of Science core collection
  • Jan 6, 2026
  • Egyptian Rheumatology and Rehabilitation
  • Ángel Denche-Zamorano + 6 more

Abstract Introduction Fibromyalgia (FM) is a chronic pain condition that affects multiple domains, including sleep quality, body composition and physical function (PF). Methods A bibliometric analysis was performed using traditional bibliometric laws. A search was conducted in the Web of Science (WoS) Core Collection database on FM syndrome and PF. A total of 447 publications (388 articles and 59 reviews) were identified. Results Annual publications output showed an exponential growth trend from 1994 to 2013 (R 2 = 0.88), followed by a phase of stabilization or slower growth from 2014 to 2023 (R 2 = 0.48). The United States was the most productive country worldwide. D. Clauw and D. Buskila were highlighted as the prolific and prominent co-authors. The Journal of Rheumatology and Clinical and Experimental Rheumatology were the journals with the highest number of publications. Keywords and Keywords Plus ® revealed thematic clusters related to FM symptoms, mental health, the impact of FM and cognitive behavior. Discussion Research on FM and PF appears to have entered a stabilisation phase after a period of exponential growth until 2013. Researchers in the United States and Spain lead global production. Clustering the Keywords revealed a progressive evolution from general health and assessment terms towards multidimensional approaches addressing the physical, cognitive, and behavioral aspects of FM. These clusters highlight the evolving scientific focus on symptoms, therapies, and the impact of the disease.

  • Research Article
  • 10.61139/ijdor.1743472
A Bibliometric Analysis of Lesion Sterilization and Tissue Repair in Primary Teeth
  • Dec 31, 2025
  • HRU International Journal of Dentistry and Oral Research
  • Fatma Dilara Baysan + 1 more

Objective: The aim of this study is to evaluate the bibliometric characteristics of studies in the literature concerning the 'lesion sterilization and tissue repair' (LSTR) technique, which involves the use of antibiotic paste for root canal disinfection in primary teeth. Materials and Methods: Within the scope of the study, a search was conducted using keywords related to the subject in the WoS-CC database. Bibliometric parameters such as the number of citations, the institution/institutions to which the authors are affiliated, the country where the study was conducted, the journal in which it was published, the index and impact factor of the journal, the publisher, the study design, the year of publication, and keywords were analyzed. Results: Using keywords related to the subject, 49 articles were reached in the WoS-CC database and 31 articles that met the eligibility criteria were selected and bibliometric analysis was performed. It was seen that clinical research studies were conducted the most (n=15) as a study design. When the distribution of published articles was examined according to years, it was seen that the interest in the subject increased as of 2012. The most studies were conducted in India and Brazil and the country with the most citations was Japan. The journals “Contemporary Clinical Dentistry”, “Cureus Journal of Medical Science” and “Journal of Clinical Pediatric Dentistry” contain the most publications related to the subject. Conclusion: In recent years, it has been observed that many publications have been added, especially in the form of clinical research articles, regarding the “lesion sterilization and tissue repair” technique. The highest number of publications on the subject have been made in India and Brazil. In order to create standard treatment guidelines in clinical practice, comprehensive studies on the subject should be encouraged.

  • Research Article
  • 10.55065/intraders.1809144
Assessing Scientific Output and Collaborative Networks in Halal Supply Chain Management Research: An R-Biblioshiny Analysis
  • Dec 31, 2025
  • InTraders International Trade Academic Journal
  • Bekir Çınar

Today, the demand for halal products from the Muslim population, which is approaching 2 billion, underscores the importance of halal supply chain management in the global business environment. In this context, identifying the requirements, principles, and gaps in the implementation of halal supply chain management—and examining not only the active actors in the chain but also the theoretical foundations from an academic perspective—is crucial for improving process efficiency. This study aims to conduct a bibliometric analysis of research published in internationally indexed journals on halal supply chain management. The bibliometric analysis of 630 publications retrieved from the Web of Science database between 1997 and 2025 covers various indicators, including the distribution of papers by year, keyword analysis, author profiles, co-authorship collaborations, citation analysis, thematic map, publication counts by country, and country-based clustering analysis. The findings reveal that the Journal of Islamic Marketing has the highest number of publications in the field; the most cited researcher is Marco Tieman; and the top three researchers with the most publications are Mohamed Syazman Ab Talib, Abid Haleem, and Mohd Imran Khan. Additionally, Malaysia—the first country to implement halal logos and certification practices—has been identified as the most productive country in this field. Furthermore, Malaysia and Indonesia are recognized as the countries with the highest levels of international collaboration. However, the analysis of the distribution of scientific productivity indicates that literature in this field has not yet reached a sufficient level of maturity, highlighting the need for further research.

  • Research Article
  • 10.46871/eams.1779813
Global Research Trends in Breast Cancer Gene Expression: A Bibliometric Study of 2020–2024 Publications
  • Dec 31, 2025
  • Experimental and Applied Medical Science
  • Nihal Üren

Purpose: This study aimed to identify and analyze articles published between 2020 and 2024 that addressed “breast cancer” and “gene expression” by examining publication trends, citation patterns, prominent journals, contributing countries, and evolving research topics within the field. Methods: A bibliometric analysis was conducted on articles related to “breast cancer” and “gene expression” that were published between 2020 and 2024 and indexed in the Web of Science (WoS) Core Collection database. The analysis included metrics such as the most cited articles, citation frequency, publication trends over time, countries with the highest publications and citations, leading authors, co-occurrence of author keywords, and the most frequently cited sources. Results: A total of 5,095 articles were identified. The highest number of publications was recorded in 2020, followed by a gradual decline toward 2024. A substantial portion of the publications originated from China and the United States of America. Most articles were published in high-impact journals and received a high number of citations. The research predominantly focused on gene expression in the context of treatment strategies and pathogenic mechanisms in breast cancer. Conclusion: This bibliometric analysis demonstrated an active and evolving research landscape in the field of breast cancer and gene expression from 2020 to 2024. The findings underscore the emphasis on elucidating pathophysiological mechanisms and investigating therapeutic approaches. These results offer valuable insights for guiding future research directions.

  • Research Article
  • 10.52642/susbed.1776843
Bibliometric Analysis of Studies in the Field of Green Accounting Based on the Web of Science (WOS) Database (1992–2024)
  • Dec 30, 2025
  • Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi
  • Tevfik Eren + 2 more

This study was conducted to perform a bibliometric analysis of research in the field of green accounting. In this context, publications indexed in the Web of Science (WoS) database were examined. As of March 30, 2024, a search was conducted in the WoS database using the keyword “green accounting”, with all WoS Core Collection criteria selected. The search results revealed no studies related to green accounting prior to 1992, while 250 studies were identified between 1992 and 2024. The highest number of publications was recorded in 2013. Among the analyzed studies, economics was found to be the most prominent research field, encompassing 118 publications. In terms of country-based contributions, the United States led the field with 61 studies. The World Bank was identified as the institution contributing the most to green accounting research. Additionally, Nicholas Z. Muller and Robert Mendelsohn were determined to be the most highly cited authors in the field. Furthermore, the study conducted co-authorship, institutional collaboration, and country collaboration network analyses, along with keyword mapping, bibliographic coupling of texts, and co-citation analysis of authors. Based on these analyses, visual mappings were created, and the discussion and conclusions were presented.

  • Research Article
  • 10.46876/ja.1811934
The Effects of Weeds on Biodiversity: A Bibliometric Analysis
  • Dec 29, 2025
  • Journal of Agriculture
  • Elvan Koç

Biodiversity is a fundamental component of ecosystem structural integrity, functionality, and sustainability. However, increasing agricultural intensification, habitat loss, and the spread of invasive weed species threaten biodiversity on a global scale. This study aims to reveal general trends, conceptual structures, and international collaboration networks in the field by examining the scientific literature on the impacts of weeds on biodiversity using a bibliometric method. A total of 479 publications published in the Web of Science (WoS) database between 2011 and 2025 were analyzed. VOSviewer and Bibliometrix (R software) were used for data processing and visualization. The findings show that the annual growth rate of studies in this research area is -4.28%, with an average of 25.46 citations per publication. France, Germany, and the United States stand out among the countries with the highest number of publications. Author network analyses revealed that Colbach, N., Fried, G., Petit, S., and Bohan, D.A. are leading researchers in the field. Keyword and thematic analyses indicate that studies are concentrated around the concepts of "biodiversity," "weed management," "agroecology," and "ecosystem services." The journals with the most publications are Agriculture Ecosystems/Environment, Agronomy for Sustainable Development, and Weed Research. Overall, the results demonstrate that the research field is evolving toward a focus on ecosystem services, sustainable agriculture, and agroecological transformation, providing a guiding scientific framework for future research.

  • Research Article
  • 10.3390/app16010318
Cyber–Physical Systems in Healthcare Based on Medical and Social Research Reflected in AI-Based Digital Twins of Patients
  • Dec 28, 2025
  • Applied Sciences
  • Emilia Mikołajewska + 4 more

Cyber–physical systems (CPS) in healthcare represent a deep integration of computational intelligence, physical medical devices, and human-centric data, enabling continuous, adaptive, and personalized care. These systems combine real-time measurements, artificial intelligence (AI)-based analytics, and networked medical devices to monitor, predict, and optimize patient health outcomes. A key development in the field of CPS is the emergence of patient digital twins (DTs), virtual models of individual patients that simulate biological, behavioral, and social parameters. Using AI, DTs analyze complex medical and social data (genetics, lifestyle, environment, etc.) to support precise diagnosis and treatment planning. The implications of the bibliometric findings suggest that the field emerges from the conceptual phase, justifying the article’s emphasis on both the proposed architectures and their clinical validation. However, most research was conducted in computer science, engineering, and mathematics, rather than medicine and healthcare, suggesting an early stage of technological maturity. Leading countries were India, the United States, and China, but these countries did not have a high number of publications, nor did they record leading researchers or affiliations, suggesting significant research fragmentation. The most frequently observed Sustainable Development Goals indicate an industrial context. Reflecting insights from medical and social research, AI-based DT systems provide a holistic view of the patient, taking into account not only physiological states but also psychological and social well-being. These systems promote personalized therapy by dynamically adapting treatment based on real-time feedback from wearable sensors and electronic medical records. More broadly, CPS and DT systems increase healthcare system efficiency by reducing hospitalizations and supporting remote preventive care. Their implementation poses significant ethical and privacy challenges, particularly regarding data ownership, algorithm transparency, and patient autonomy.

  • Research Article
  • 10.15381/gtm.v28i56.32136
Patrones y tendencias de la producción científica sobre calidad del gasto público en las municipalidades: Una revisión bibliométrica
  • Dec 26, 2025
  • Gestión en el Tercer Milenio
  • Dina Verónica Chire Cruz

The quality of public spending has gained increasing importance due to its contribution to local development and the efficiency of public service delivery. The objective of this study was to analyze the patterns and trends in scientific production on the quality of public spending in municipalities through a bibliometric analysis of the available literature. The methodology employed was qualitative, exploratory, and descriptive, and exclusively using the Scopus database. Seventy-one scientific publications related to the topic were analyzed, identifying an average annual growth of 5% in research output, with a significant increase starting in 2001. Among the most prominent authors are Rocha, Afonso, Hortas-Rico, and Pascual, while the journals with the highest number of publications were Applied Economics (Taylor &amp; Francis Online), Local Government Studies (Taylor &amp; Francis Online), and Economía Aplicada (University of Zaragoza). The United States, the United Kingdom, and Australia lead scientific production from the social and economic sciences perspectives. Analysis of the thematic map reveals that the most relevant topics are strategic approach, public policies, efficiency, and national development, along with emerging approaches such as the top-down model and multilevel planning. It is concluded that the study of the quality of public spending has reached conceptual maturity, highlighting challenges related to methodological integration and global collaboration. Therefore, it is recommended to include new databases that strengthen the evidence found and to incorporate contemporary approaches in public management.

  • Research Article
  • 10.1097/md.0000000000046735
The research trends of macrophages in acute kidney injury: A bibliometric analysis
  • Dec 26, 2025
  • Medicine
  • Xiangyu Zhang + 9 more

Objective:In recent years, the study of macrophages has gained prominence as a promising avenue for understanding the pathogenesis and therapeutic prospects of acute kidney injury (AKI). In this work, we utilize a bibliometric analysis to map the existing research landscape concerning macrophages in the context of AKI. We aim to provide valuable insights and scholarly references that can facilitate the advancement of comprehensive research and innovation in this field. Our goal is to provide valuable knowledge and academic sources that support the progress of thorough research and breakthroughs in connected fields.Methods:We incorporated studies focused on macrophages in AKI that were retrieved from the Web of Science Core Collection. All publications were exported in plaintext full-record format and subsequently analyzed using CiteSpace 6.4.R1 for bibliometric evaluation.Results:A total of 1483 records meeting the inclusion criteria were analyzed. The number of publications in the 1st 12 years was relatively low, but there was a notable increase in publications in 2019 and 2021. The research, encompassing contributions from 56 countries and 437 institutions, is led by China and US Department of Veterans Affairs. The authors with the highest number of publications are Hans-Joachim Anders and Mark D. Okusa, and Bonventre JV was the most frequently cited author. The journal with the highest number of co-citations is Kidney International. Prominent keywords in the literature include macrophages, inflammation, and extracellular vesicles. Keywords extracted from the analysis mainly focus on AKI, expression, acute renal failure, activation, inflammation, and macrophages.Conclusion:This research provides a comprehensive bibliometric evaluation, thereby enhancing our understanding of the current state of macrophage studies in AKI. As a result, it assists both experienced researchers and newcomers by facilitating quick access to crucial information and promoting the extraction of innovative concepts within this specialized field.

  • Research Article
  • 10.1097/md.0000000000046830
Trends and hotspots in global halitosis research: A bibliometric analysis from 2010 to 2025
  • Dec 26, 2025
  • Medicine
  • Zhulin Wu + 4 more

Objective:This study aims to utilize bibliometric methods to examine the global English-language literature on halitosis, with the goal of identifying research hotspots and suggesting potential future research directions in this field.Methods:A comprehensive search of PubMed was conducted for literature related to halitosis, spanning from January 2010 to July 2025. Bibliometric analysis was performed using the Medpulse database and the R software package bibliometrix, including statistical analysis of literature data, as well as topic and co-occurrence analyses.Results:The analysis included a total of 1634 articles, representing contributions from corresponding authors across 19 countries, with China and the USA leading in publication output. There has been a consistent annual increase in publications related to halitosis. Japanese institutions and authors are particularly active, with their frequent publications contributing to their influence and prominence in this field. Fukuoka Dental College emerged as the institution with the highest number of publications. The majority of these articles are published in journals dedicated to oral health. Key topics of study include halitosis, oral health, oral malodor, periodontitis, probiotics, oral hygiene, volatile sulfur compounds, periodontal disease, and quality of life, etc. Thematic evolution analysis indicates that oral diseases and research involving children remain promising areas for future investigation.Conclusion:Bibliometric analysis indicates that the diagnosis and treatment of halitosis, along with research focused on pediatric populations and multidisciplinary approaches, have emerged as recent research hotspots and directions in the field.

  • Research Article
  • 10.21037/jgo-2025-557
Bibliometric analysis on the correlation between colorectal cancer and tumor microenvironment [2009–2024]
  • Dec 26, 2025
  • Journal of Gastrointestinal Oncology
  • Longjun Huang + 4 more

BackgroundColorectal cancer (CRC) is a common malignancy worldwide, and its incidence and mortality are increasing annually. In recent years, researchers have gradually realized that the tumor microenvironment (TME) plays a crucial role in the development and progression of CRC. The in-depth study of CRC and its microenvironment provides not only a new perspective for understanding the occurrence and development of tumors, but also potential new strategies for clinical treatment. This study aims to explore the research hotspots and development trends between CRC and TME through bibliometric analysis.MethodsThe Web of Science Core Collection (WoSCC) was used to retrieve literature related to CRC and the TME published from 2009 to 2024. CiteSpace software and VOSviewer software were used to evaluate and visualize the authors, journals, institutions, countries, keywords and citations.ResultsA total of 8,410 relevant articles were analyzed, and the number of published articles tended to increase. The countries and institutions that had with the highest number of publications in this field were China and Sun Yat-sen University. Ogino, S was the most prolific author and the most cited literature was Sung, Hyuna’s article “Global cancer statistics 2020” published in the CA-A Cancer Journal for Clinicians. The journals with the most published articles and citations were Cancers and Clinical Cancer Research, respectively. Keyword analysis revealed that the current popular research topics included the “immunotherapy”, “tumor microenvironment”, “prognosis” and “inflammation”.ConclusionsThe study of CRC and the TME is still a hot topic. Future research will focus more on the interaction between various immune cells and molecules, study the expression of cancer-related genes and proteins, and explore new therapeutic targets and prognostic markers. These findings provide strong support for the precise and individualized treatment of cancer.

  • Research Article
  • 10.21555/rpc.v7i2.3393
Mapping international research in Cinema, Audiovisual, and Animation: A metric study in Scopus
  • Dec 24, 2025
  • Revista Panamericana de Comunicación
  • Thaís Dias Medeiros + 1 more

This article maps out the international scientific output in Cinema, Audiovisual, and Animation in the Scopus database. It uses bibliometrics as its methodological approach. Our research identified a diversity of publication languages, with English being the most commonly used language. The article was the dominant documentary typology, followed by the review, which may indicate a publication trend in the area. Among the publication vehicles, journals from the United Kingdom and Spain stand out. The countries with the highest number of publications in Cinema, Audiovisual, and Animation differ from the general ranking, and Brazil and Spain stand out when it comes to publications on the topic. It is concluded that production in the area, which began in 1980, has been growing slowly but steadily, especially since the 2000s, predominantly in the areas of Arts and Humanities, and Human Sciences. This research presents a broad and international view of the topic and suggests new studies in other databases as well as in specific countries.

  • Research Article
  • 10.47460/minerva.v6isp.257
Process Management for Service Quality in the Health Sector: A Bibliographic Review
  • Dec 24, 2025
  • Minerva
  • Miguel Antonio Delgado Valera

A descriptive and exploratory bibliometric study was conducted on articles published in SCOPUS between 2021 and 2025. The analysis examined annual scientific production, journals with the highest number of publications, the most productive countries, authors, and institutions, as well as the frequency of keywords. The results highlighted the importance of studying process management in service quality within the health sector, as it represents a key tool for improving health systems for the benefit of society.

  • Research Article
  • 10.21037/tau-2025-656
A bibliometric analysis of ultrasound-based evaluation in renal transplantation
  • Dec 24, 2025
  • Translational Andrology and Urology
  • Yang Pu + 3 more

BackgroundUltrasound is a widely used and effective imaging modality for evaluation in renal transplantation. This study aimed to provide a comprehensive bibliometric analysis of the research landscape and emerging trends in the use of ultrasound for renal transplant assessment.MethodsRelevant articles published between January 2010 and June 2025 were retrieved from the Web of Science (WoS; Science Citation Index Expanded) and PubMed [randomized controlled trial (RCT)] databases using the keywords “ultrasound” and “renal transplant”. Publications were screened by article type, language, abstract, and keywords. Bibliometric and visualization analyses were performed using VOSviewer and the bibliometrix R package.ResultsA total of 268 original research articles were included. The analysis demonstrated a notable rise in research activity since 2020, accompanied by extensive international collaboration, with the United States identified as the leading contributor. Transplantation Proceedings was the most prolific journal, while Clinical Hemorheology and Microcirculation had the highest citation count. Fananapazir G and Haberal M have the highest number of publications, while Brabrand K and Midtvedt K have the highest number of citations. Zhengzhou University was among the most active Chinese institutions in recent years. Machine learning (ML), shear wave elastography (SWE), and contrast-enhanced ultrasound (CEUS) have emerged as active research topics in the field.ConclusionsUltrasound remains a key research focus in the imaging evaluation of renal transplants, with substantial potential for future advancement. The increasing integration of ML with ultrasound-based techniques represents a promising direction, with the potential to enhance diagnostic accuracy and clinical decision-making in renal transplant assessment.

  • Research Article
  • 10.1097/md.0000000000046595
Research progress of exosome-hydrogel between 2013 and 2023 from the perspective of bibliometrics
  • Dec 19, 2025
  • Medicine
  • Jian Li + 3 more

Introduction:Exosomes, particularly those derived from mesenchymal stem cells, play an important role in treating and diagnosing various diseases. Hydrogels have been demonstrated to be suitable materials for encapsulating exosomes to preserve their biological activity and enable controlled release. Recently, the incorporation of exosomes into hydrogels has emerged as an important research field. This study aims to reveal trends and hotspots of exosome-hydrogel research results over the last 10 years.Materials and methods:Publications about exosome-hydrogel between 2013 and 2023 were searched from the Web of Science Core Collection. VOSviewer (version 1.6.18), CiteSpace (version 6.2.R2), the R package “bibliometric” (version 3.2.1), and Scimago Graphica were employed for further bibliometric analysis and data visualization.Results:From January 2013 to December 2023, 1354 documents (1093 articles and 261 reviews) were written by 7651 authors from 1612 institutions across 72 countries and published in 392 journals. China had the highest number of publications (630), and Shanghai Jiaotong University published the most articles (53). Soft Matter is the most prolific journal (36 documents, average citation: 19.8%), whereas ACS Nano (25 documents, average citation: 70.3%) is the most authoritative journal in this field. Z Gu (13 documents) and A Hao (10 documents) were the most productive authors. The most popular keywords were “hydrogel,” “vesicles,” “exosomes,” “drug delivery,” “nanoparticles,” “release,” and “mesenchymal stem cells.” Furthermore, our findings indicated that exosome-hydrogel compounds were most frequently used in diabetic wound healing and bone regeneration.Conclusions:This study revealed a growing interest in exosome-hydrogel for managing related diseases, especially, diabetic wound healing and bone regeneration. This study offers new insights into research fields of exosome-hydrogel, and may benefit further research.

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