High Content Of Unsaturated Fatty Acids Research Articles

Metabolism of individual fatty acids by sheep depot adipose tissue in vivo and in vitro

1. 1. Sheep adipose tissue and plasma have high stearate and low unsaturated fatty acid content compared to rat, dog and man. 2. 2. In control animals in vivo uptake as well as release of various fatty acids by adipose tissue could be demonstrated. In vitro net release occurred. Fasting resulted in a decrease in tissue stearate and increased release of fatty acids. Adrenaline and noradrenaline had minimal lipolytic effect in vivo and in vitro. 3. 3. Variations in the turnover rate of individual fatty acids were observed.

Unsaturated fatty acids in acne.

Long-continued, low-fat acne diets often cause weight and energy loss, and resistance to infection may be lowered. Therefore, I decided to give supplemental unsaturated fatty acids to see what the effect would be on the weight loss and on the acne itself. Safflower-oil emulsion * was first chosen as an adjunct to the regular diet for acne because of its high unsaturated fatty acid content. However, most patients found it difficult to take adequate quantities without disturbing their digestion. Corn oil † was then substituted. It was used in the preparation of food in place of all other animal or vegetable fats, and it proved to be a far more acceptable source of unsaturated fatty acids. The average saturation of common fats is as follows: Hydrogenation solidifies fat but reduces the per cent of unsaturated fatty acids and creates unnatural isomers of linoleic acid. Linoleic acid is the principal unsaturated fatty acid found in our dietary fats. Isomers are not utilized as unsaturated fatty acids by the body, and so all hydrogenated fats were carefully eliminated from the diet. Few studies of the effects of unsaturated fatty acids on acne were noted in a brief search