High Relative Sensitivity Research Articles

Multiple lattice sites occupied AlTaO4:Cr3+ phosphor for luminescence ratiometric thermometry and NIR light source

Cr3+-doped near infrared (NIR) phosphors have promising applications in NIR light sources and optical temperature detection. The development of materials with high relative sensitivity and efficient broadband NIR luminescence is the key. In this paper, we report a new multifunctional NIR phosphor AlTaO4:Cr3+, which contains both narrow-band emission associated with 2Eg→4A2 g transition and broadband emission induced by the 4T2 g→4A2 g transition owing to Cr3+ occupies both AlO6 and TaO6 lattice sites. The R-line (2Eg→4A2 g) emission and its anti-Stokes phonon sideband emission follow the Boltzmann distribution, and the thermometer constructed accordingly reaches a maximum Sr of 1% K−1 at 110 K. Under 425 nm excitation, the broad emission band (FWHM = 200 nm) reaches maximum at 880 nm with an internal quantum efficiency of 62.8%. The NIR LEDs prepared with AlTaO4:Cr3+ confirm the application value in NIR light sources.

Ratiometric luminescent thermometry for the third bioimaging window by Er3+ doped garnet with large Stark splitting

Based on the 4I13/2 → 4I15/2 emission (1450–1700 nm) of Er3+ in garnet, which is matching well with third bioimaging window (NIR-III), we propose a ratiometric near-infrared (NIR) thermometer (YAGG:Ce-Er) in NIR-III by utilizing thermal coupling between Stark levels of 4I13/2, where energy levels were split into seven sublevels (I–VII). The energy gaps between Stark sublevel VII and I (ΔEVII-I) and V and I (ΔEV-I) of the 4I13/2 level, calculated from the temperature dependence of intensity ratios of the two selected thermal couples, corresponded well with the theoretical values. This agreement supports the analysis that the system can be utilized as a Boltzmann thermometry. Moreover, the relative sensitivity (Sr) within the temperature range commonly encountered in organisms (25–60 °C) reached a value of 0.63 ± 0.03% K−1 for the VII/I ratio and 0.57 ± 0.07% K−1 for the V/I ratio. These high relative sensitivity values indicate the strong potential for practical application in various biological fields.

Performance evaluation of photonic crystal fibre sensor for controlled drugs detection: a simulation approach

This study proposes a simple and efficient Photonic Crystal Fibre sensor design for the detection of controlled drugs such as cocaine, amphetamine, and ketamine. The design uses a pentagonal core hole and circular cladding air holes in 2 layers, made of fused silica substrate. The sensing performance of the proposed PCF design is evaluated using COMSOL Multiphysics and Finite Element Method, operating in the visible and infrared range from 0.4 to 3.2 μm. Results show that the proposed PCF design achieves high relative sensitivities of 99.55%, 99.75%, and 99.99% for cocaine, amphetamine, and ketamine, respectively, at the optimum wavelength of 0.4 μm. Additionally, the design is robust, showcasing minimal variations in relative sensitivities with changes in pitch distance, air hole diameter, and core hole length. These findings make the proposed PCF design a promising candidate for practical controlled drug sensing.

High-sensitive nonthermally coupled upconversion for ultralow temperature sensing

Upconversion based nanothermometry has received much attention due to its merits of stability, narrow band emission and rich emission peaks. However, the previous works are mainly focused on the emissions from thermally coupled energy levels which is theoretically limited by Boltzmann distribution theory with resultant low temperature sensitivity in particular at ultralow temperatures. Here we report a LiYF4:Yb/Ho@LiYF4 core-shell nanostructure to improve the sensitivity at low temperatures by taking advantage of non-thermally coupled energy levels of Ho3+. In detail, the green upconversion emission of Ho3+ shows an increase with reducing temperature while its red upconversion emission presents a decline during the same process. This is primarily due to the suppression of the non-radiative multi-phonon relaxation occurred at the green emitting levels (5F4,5S2) and the intermediate level (5I6) at low temperatures. Such a feature contributes to a high relative sensitivity of 7.17%/K at 11 K, much higher than reported values. Our results provide a promising candidate for the development of nanothermometer with high-sensitive low-temperature sensing performance.

Ratiometric optical temperature sensor with wide range and high sensitivity based on the emission of Dy3+ ion-doped Ca5(PO4)2SiO4 phosphor

There is an urgent demand for the development of non-contact optical temperature sensors that possess a wide temperature measurement range and high sensitivity, particularly for extreme environments. In this study, Dy3+-doped Ca5(PO4)2SiO4 phosphors were prepared and comprehensively analyzed. XRD, SEM, EDS, Raman spectrum, as well as excitation and emission spectrum were employed to investigate the structural, photoluminescent, and temperature-dependent properties of the phosphors. Under 349 nm excitation, the luminescence intensity ratio (LIR) of Dy3+ ions at 453 nm (4I15/2) and 480 nm (4F9/2) exhibited a strong correlation with temperature within the range of 296-1073 K. By fitting the FIR of I453 and I480 at different temperatures using Boltzmann equations, we observed a larger energy gap, indicating high relative sensitivity of the synthesized phosphor. Additionally, Ca4.95(PO4)2SiO4: 0.05Dy3+ phosphor shows excellent temperature repetitiveness. These findings highlight the potential applications of Ca5(PO4)2SiO4: Dy3+ phosphors as highly sensitive ratiometric optical temperature sensor over a wide temperature range.

Synthesis and optimization of Nd3+doped hydroxyapatite as NIR-to-NIR nanothermometers

Neodymium (Nd)-doped nanomaterials show excellent biothermal sensing (TS) properties due to the thermally coupled near-infrared (NIR) emission. However, Nd-doping in biomaterials like hydroxyapatite (HA) may offer added biocompatibility, a major concern for TS materials. Here we report the optimisation of Nd-doped hydroxyapatite (HAP) nanophosphors as potential nanothermometers operating within the biological windows. Different doping concentrations were analysed where 5% Nd3+ doped HAP (HAP:5%Nd) showed the highest luminescence output, which improved 4-fold after the annealing. Thus, the effect of annealing was also analyzed on optical properties and thermal sensing. The ratiometric luminescence thermal sensing of HAP:5%Nd revealed the linear behaviour in the temperature range of 25– 60 °C with a high relative thermal sensitivity value of 0.37% K−1 at 298 K. Furthermore, the synthesized nanocrystals showed excellent biocompatibility in vitro. Overall, HAP:5%Nd showed properties for implementation in biomedical applications.

N-UV triggered green emitting Er3+ doped Zirconia: A bifunctional material for solid-state lighting and optical thermometry

In the current piece of work, we have synthesized the Er3+-activated ZrO2 and illustrated the bifunctional utility of this material for solid-state lighting and non-contact optical thermometry. The synthesized samples were characterized by XRD, XPS, and PL techniques for their structural, surface, and luminescence studies. Under the excitation of 377 nm, characteristic green emission corresponding to intra 4f-4f transitions of Er3+ is obtained. The concentration quenching effect was observed beyond 1.2 mol % concentration of doping. Using Dexter's theory, it was revealed that dipole-quadrupole interactions are predominantly responsible for concentration quenching. The Photometric study was performed using the PL data. For the most intense phosphor, a highly pure green color (color purity ∼ 97.6%) and CCT ∼ 5375 K is observed. Furthermore, the temperature-sensing capability of the most intense sample has also been explored by triggering the synthesized phosphor by n-UV light. The temperature sensing performance is checked by measuring variations in the fluorescence intensity ratio (FIR) of the thermally coupled levels of Er3+ with temperature. The synthesized phosphor gives high relative sensitivity (1.19% K−1 at 303 K)) and absolute sensitivity (11.39 × 10−4 at 603 K)) values. These results suggest that n-UV-triggered Er3+ doped ZrO2 can be a promising bifunctional material for applications in solid-state lighting and non-contact optical thermometry.

Exploration of Coumarin Derivative: Experimental and Computational Modeling for Dipole Moment Estimation and Thermal Sensing Application.

The Optical properties of the FBTC (1-((4-((5-chlorobenzo[d]oxazol-2-ylthio)methyl)-1H-1,2,3-triazol-1-yl)methyl)-3H-benzo[f]chromen-3-one) molecule were studied experimentally and theoretically. The spectra of absorption and fluorescence were recorded in various solvents to explore their Solvatochromic behavior and dipole moment at room temperature. To determine the ground and excited state of dipole moment experimentally and theoretically, we employed different Solvatochromic techniques, including microscopic solvent polarity functions developed by Lippert, Bakhshiev, Kawaski-Chamma-Viallet, and Reichardt's, as well as density functional theory (DFT) and time-dependent density functional theory (TD-DFT) methods. The stability of the excited state dipole moment in FBTC is higher. Using prime functional, FBTC was optimized in its ground state, and its HOMO (Highest Occupied Molecular Orbital) and LUMO (Lowest Unoccupied Molecular Orbital), energies were estimated. These values were then compared with those obtained through cyclic voltammetry. Based on the HOMO and LUMO values given, we calculated the global reactivity parameter and energy gap, which was found to be low at 3.77eV. This study also includes an estimation of electron absorption energies and oscillator strength. Natural population analysis (NPA), Milliken atomic charge, and molecular electrostatic potential (MESP) map are correlated. In addition, FBTC exhibited exceptional physiological temperature sensing behaviour from 20°C -65°C with high relative sensitivity and firm stability. Hence these results confirm that FBTC is a potential candidate for photonic devices and it's also applicable in optical temperature sensing.

Tunable luminescence and noncontact temperature sensing of oxyfluoride glass ceramics containing Na(Y1.5Na0.5)F6:Bi3+/Eu3+ nanocrystals

The oxyfluoride glass ceramics (GCs) containing novel Na(Y1.5Na0.5)F6 (NYNF) nanocrystals: Bi3+/Eu3+ were successfully fabricated. The results of the transmission electron microscope (TEM) showed that NYNF nanocrystals (40–70 nm) are distributed in the glass matrix. Moreover, the luminescence properties of Bi3+/Eu3+ ions-doped NYNF GCs were tested and analyzed. The NYNF GCs exhibit strong emission at blue (412 nm, Bi3+) and red (613 nm, Eu3+) wavelengths when excited with near-ultraviolet (n-UV) light at 288 nm. The emission color can be adjusted from blue (0.1506, 0.0655) to violet (0.3535, 0.1929) by increasing the Eu3+ ion content. Notably, the sample exhibited significant temperature-sensing characteristics as calculated by fluorescence intensity ratio (FIR), with high relative sensitivity (1.731 % K−1) at 548 K. These findings demonstrate the potential application of NYNF: Bi3+/Eu3+ GCs in achieving tunable multicolor luminescence and noncontact temperature measurement.

Designing a Graphene Metasurface Organic Material Sensor for Detection of Organic Compounds in Wastewater.

In many fields, such as environmental monitoring, food safety, and medical diagnostics, the identification of organic compounds is essential. It is crucial to create exceptionally sensitive and selective sensors for the detection of organic compounds in order to safeguard the environment and human health. Due to its outstanding electrical, mechanical, and chemical characteristics, the two-dimensional carbon substance graphene has recently attracted much attention for use in sensing applications. The purpose of this research is to create an organic material sensor made from graphene for the detection of organic substances like phenol, ethanol, methanol, chloroform, etc. Due to its high surface-to-volume ratio and potent interactions with organic molecules, graphene improves the sensor's performance while the metasurface structure enables the design of highly sensitive and selective sensing elements. The suggested sensor is highly sensitive and accurate at detecting a broad spectrum of organic molecules, making it appropriate for a number of applications. The creation of this sensor has the potential to have a substantial impact on the field of organic sensing and increase the safety of food, medicine, and the environment. The graphene metasurface organic material sensor (GMOMS) was categorized into three types denoted as GMOMS1, GMOMS2, and GMOMS3 based on the specific application of the graphene chemical potential (GCP). In GMOMS1, GCP was applied on both the CSRR and CS surfaces. In GMOMS2, GCP was applied to the CS surface and the surrounding outer region of the CSRR. In GMOMS3, GCP was applied to the CSRR and the surrounding outer region of the CSRR surface. The results show that all three designs exhibit high relative sensitivity, with the maximum values ranging from 227 GHz/RIU achieved by GMOMS1 to 4318 GHz/RIU achieved by GMOMS3. The FOM values achieved for all the designs range from 2.038 RIU-1 achieved by GMOMS2 to 31.52 RIU-1 achieved by GMOMS3, which is considered ideal in this paper.

Multi-b-values-fitting readout-segmentation of long variable echo-trains diffusion-weighted imaging (RESOLVE DWI) in evaluation of disease activity and curative effect of axial spondyloarthritis (axSpA).

Disease activity is relevant to the treatment and prognosis of axSpA, and methods to quantitatively assess disease activity and efficacy of axSpA are still being explored. The purpose of this study was to find an optimal quantitative indicator for evaluating disease activity and curative effect of axSpA, using multi-b-values-fitting RESOLVE DWI. The prospective study included 106 patients divided into axSpA group (n=89) and no-axSpA group (n=17) by Assessment of Spondyloarthritis international Society (ASAS) criteria. The axSpA group were divided into active group and inactive group according to ASDAS-CRP. The active group treated with systematic tumour necrosis factor inhibitors (TNFi) was selected as treatment group (n=20). All patients underwent MRI examination of sacroiliac joints (SIJs), including RESOLVE DWI. The ADC values of subchondral bone marrow in SIJs were measured (ADC50,500 was b=50,500s/mm2 fitting, ADC50,700 was b=50,700s/mm2 fitting, and ADC50,500,700 was b=50,500,700s/mm2 fitting). By comparing the ADC values between different groups, a relatively optimal b-values-fitting sequence was obtained, further evaluating curative effect of the treatment group. The ADC values of axSpA group, inactive group and active group SIJs were all higher than those of no-axSpA group. The ADC values of active group SIJs were all higher than those of inactive group. ADC50,500,700 had the largest AUC, relative higher sensitivity and specificity while taking account of the image quality than ADC50,700 and ADC50,500 between different groups. In the treatment group, there was no significant difference in ADC values between pre-treatment and 3 weeks, 3 weeks and 6 weeks, 6 weeks and 12 weeks (all P>0.0083, Bonferroni-corrected threshold), while the decreased ADC values in the interval of 6 weeks or more were statistically significant (all P<0.0083, Bonferroni-corrected threshold). Multi-b-values-fitting (b=50,500,700s/mm2) RESOLVE DWI has a certain advantage in evaluating disease activity of axSpA. It was worth noting that short-term review (3 weeks or less) of RESOLVE DWI was unsatisfactory and review at 6 weeks or later would help to evaluate curative effect of axSpA.

A Novel Dye-Modified Metal-Organic Framework as a Bifunctional Fluorescent Probe for Visual Sensing for Styrene and Temperature.

A novel fluorescent probe (C460@Tb-MOFs) was designed and synthesized by encapsulating the fluorescent dye 7-diethylamino-4-methyl coumarin (C460) into a terbium-based metal-organic framework using a simple ultrasonic impregnation method. It is impressive that this dye-modified metal-organic framework can specifically detect styrene and temperature upon luminescence quenching. The sensing platform of this material exhibits great selectivity, fast response, and good cyclability toward styrene detection. It is worth mentioning that the sensing process undergoes a distinct color change from blue to colorless, providing conditions for the accurate visual detection of styrene liquid and gas. The significant fluorescence quenching mechanism of styrene toward C460@Tb-MOFs is explored in detail. Moreover, the dye-modified metal-organic framework can also achieve temperature sensing from 298 to 498 K with high relative sensitivity at 498 K. The preparation of functionalized MOF composites with fluorescent dyes provides an effective strategy for the construction of sensors for multifunctional applications.

Optical thermometry based on fluorescence intensity ratio of doped ions and matrix in CaWO4: Eu3+ phosphors

In this work, Eu3+ doped CaWO4 phosphors with various concentrations were obtained by hydrothermal method. XRD and the FE-SEM were used to indicate the structure and morphology of the samples. The temperature-dependent excitation and emission spectra of Eu3+ doped CaWO4 phosphors were measured. Analyzing the test results found that the luminescence of WO42− decreased significantly with the increase of temperature, showing a normal thermal quenching trend, but the luminescence of Eu3+ showed a novel trend of first rising and then decreasing. This novel phenomenon is the result of enhancement of energy transfer effect from the matrix to Eu3+ with temperature increase. The thermal quenching trend of Eu3+ and WO42− luminescence is markedly different. So, the high relative sensitivity is obtained by using FIR of Eu3+ and WO42− to represent temperature. The maximum of relative sensitivity was 3.25% K−1 at 303 K. Meanwhile, the luminescence color of phosphor changed significantly from blue to orange-red with increasing temperature. To sum up, Eu3+ doped CaWO4 phosphor was a potential optical temperature sensing material.

Visual ratiometric optical thermometer with high sensitivity and excellent signal discriminability based on LiScSiO4:Ce3+, Tb3+ thermochromic phosphor.

Developing optical thermometer phosphors with high sensitivity, high signal discriminability and strong fluorescence intensity is ongoing. A dual-emitting thermochromic phosphor, LiScSiO4:Ce3+, Tb3+, was successfully synthesized via solid-state reaction method. The crystal structure, electronic structure, luminescent performance and thermal luminescence behaviors as well as the luminescence mechanism of LiScSiO4:Ce3+, Tb3+ were systematically investigated. Due to the energy transfer and different thermoluminescence behaviors between Ce3+ and Tb3+, high relative sensitivity (2.2% K-1@473K), excellent signal discriminability (5747cm-1), outstanding temperature resolution (0.067K) and good repeatability, as well as efficient emission at high temperatures were achieved based on the fluorescence intensity ratio of Ce3+ and Tb3+, indicating its potential in ratiometric optical thermometer. Moreover, the excellent visualizing thermochromic enable LiScSiO4:Ce3+, Tb3+ to be used as safety sign in variable temperature environment to monitor temperature distribution.

Unsafe food additive sensing through octagonal-core photonic crystal fibre sensor

To detect food additives, a simple photonic crystal fibre design based on an octagonal hole and hollow circular cladding holes in two layers has been introduced. The numerical study of the design is conducted by simulation in the COMSOL Multiphysics software with the infiltrated test analytes: saccharin, sorbitol, and butyl acetate, operating in the wavelength variation from 1.6 to 4.0 μm. The performance of the proposed sensor is determined by analysing the principal optical parameters: effective refractive index, power fraction, relative sensitivity, confinement loss, chromatic dispersion, propagation constant, V-parameter, spot size, and beam divergence. At the optimal wavelength of 2.0 μm, the sensor design depicts high relative sensitivities of 98.06% for saccharin, 97.05% for sorbitol, 95.81% for butyl acetate, and 3.82 × 10−23 dBm−1 for saccharin, 3.44 × 10−22 dBm−1 for sorbitol, and 1.81 × 10−21 dBm−1 for butyl acetate for confinement loss, which is extremely low. Hence, the proposed food additive sensor is suitable for actual sensing applications based on these obtained results.

Photonic crystal fibre for blood components sensing

A photonic crystal fibre (PCF)-based sensor has been proposed and thoroughly investigated for the identification of blood components, including red blood cells, haemoglobin, white blood cells, plasma, and water. To evaluate the sensor's sensing and propagation properties, a numerical analysis was performed using the COMSOL Multiphysics software. The proposed sensor design features an octagonal core and two layers of cladding with octagonal and circular air holes. At the optimal wavelength of 7.0 μm, the extensive simulation results confirms that the proposed sensor achieves high relative sensitivity of 99.89%, 99.13%, 97.95%, 97.77%, and 96.68% for red blood cells, haemoglobin, white blood cells, plasma, and water, respectively. Furthermore, the design demonstrates favourable confinement loss, propagation constant, V-parameter, spot size, and beam divergence. Therefore, the proposed PCF-based sensor holds great promise not only for medical sensing applications but also for optical communications. Its advanced design and highly sensitive capabilities make it a valuable tool for a wide range of potential applications in the biomedical and telecommunications fields.

Multifunctional core-shell nanoparticles for temperature sensing and anti-counterfeiting

In this paper, the multi-functional multi-layer core-shell structure NaYF4: Ce3+/Eu3+@NaYF4 @NaYF4: Ho3+/Yb3+ nanoparticles (NPs) were prepared. These multi-layer NPs can be applied in temperature sensing with high relative sensitivity. Moreover, these NPs can be used in multimode optical anti-counterfeiting. Based on structure design and doped earth ions optimized, the maximum relative sensitivity is further promoted from 0.9 %·K−1 at 234 K (Eu/Ho) to 5.1 %·K−1 at 113 K (Ce/Eu@Y@Ho/Yb) by the blocking effect of the inter layer and by cross-relaxation of introducing Ce3+ and Yb3+ ions. Meanwhile, by introducing Ce3+ and Yb3+ ions, the NPs provide multimode emissions under multiple excitations, which are beneficial for the application of optical anti-counterfeiting. The NPs present increased sensitivity of temperature sensing and improved security of optical anti-counterfeiting, which has promising applications in biological cell calibration, micro-integrated circuits, etc.

Wave-Shaped Microstructure Cancer Detection Sensor in Terahertz Band: Design and Analysis

For the quick identification of diverse types of cancer/malignant cells in the human body, a new hollow-core optical waveguide based on Photonic Crystal Fiber (PCF) is proposed and numerically studied. The refractive index (RI) differs between normal and cancerous cells, and it is through this distinction that the other crucial optical parameters are assessed. The proposed cancer cell biosensor’s guiding characteristics are examined in the COMSOL Multiphysics v5.5 environment. The Finite Element Method (FEM) framework is used to quantify the display of the suggested fiber biosensor. Extremely fine mesh elements are additionally added to guarantee the highest simulation accuracy. The simulation results on the suggested sensor model achieve a very high relative sensitivity of 99.9277%, 99.9243%, 99.9302%, 99.9314%, 99.9257% and 99.9169%, a low effective material loss of 8.55×10−5 cm−1, 8.96×10−5 cm−1, 8.24×10−5 cm−1, 8.09×10−5 cm−1, 8.79×10−5 cm−1, and 9.88×10−5 cm−1 for adrenal gland cancer, blood cancer, breast cancer type-1, breast cancer type-2, cervical cancer, and skin cancer, respectively, at a 3.0 THz frequency regime. A very low confinement loss of 6.1×10−10 dB/cm is also indicated by the simulation findings for all of the cancer cases that were mentioned. The straightforward PCF structure of the proposed biosensor offers a high likelihood of implementation when used in conjunction with these conventional performance indexes. So, it appears that this biosensor will create new opportunities for the identification and diagnosis of various cancer cells.

PO-05-085 ENHANCED PAUSE ALGORITHM FOR INSERTABLE CARDIAC MONITOR REDUCES CLINICAL REVIEW BURDEN

A critical feature of an Insertable Cardiac Monitor (ICM) is to identify clinically significant pauses/bradycardic events in patients (pts) with unexplained syncope. Reducing the number of false positive pause episodes will reduce the clinic review workload. To evaluate an enhanced pause detection algorithm and reduce the clinical burden of evaluating pause episodes while maintaining high relative sensitivity and increasing specificity. The development set consisted of 1033 real world stored LUX-Dx (Boston Scientific) ICM pause events (347 pts) which were selected to include more episodes with low signal to noise ratio (SNR). Another independent test set of 728 real world stored Pause events (93 pts) was randomly selected from a large pool of sequestered patient episode data and adjudicated by two experts until agreement as to specificity. The LUX-Dx pause algorithm uses a proprietary two-step detect/confirm process: step 1 detects when an R-R interval is longer than a programmed threshold, and step 2 confirms (or rejects) a suspected pause after analyzing for broadband myopotential noise and signal-to-noise ratios (SNR) (undersensing). Using the development set (1033 episodes), we have enhanced this algorithm to reject false positive pauses caused by noise and low amplitude signals. The false positive (FP) reduction was 62.5% in the Development set and 48.6% in the Test set. Further, the pt-level reduction in FP episodes ranged from 31.3 - 74.1%. No previously detected true positives were eliminated by the enhanced algorithm in either the development or test sets. This enhanced pause detection algorithm maintained high relative sensitivity, and exhibited a substantial reduction in false pauses, which would decrease the review burden in ICM device clinics while preserving sensitivity to detect clinically important events.Tabled 1DatasetNumber of PatientsNumber of episodesRelative Sensitivity (%)Reduction in FP episodes (%)Reduction in patients with FP events (%)Development347103310062.574.1Test9372810048.631.3 Open table in a new tab

Luminescence, optical and temperature sensitive characteristics of Tm3+ /Yb3+ doped fluoride phosphosilicate glass ceramics

Yb3+/Tm3+ doped fluoride phosphosilicate glass ceramics with Sr6Ca4(PO4)6F2 nanocrystals were prepared by the controlled crystallization method. The research results of up-conversion (UC) spectra showed that the optimal dopant concentration of Yb3+ and Tm3+ was 3.0 and 0.1 mol%, respectively. In the visible range, the transmissivity of the precursor glass (PG) was close to 90%, while that of glass ceramics was approximately 82%. And the luminescence intensity of glass ceramics was stronger than that of PG. The Rietveld XRD refinement results confirmed that Yb3+ and Tm3+ ions partially entered the Sr6Ca4(PO4)6F2 crystal to form the solid solution. The highest relative sensitivity (Sr-max) of glass ceramics based on thermally coupled energy levels (TCELs) was 2.77% K-1 (@298 K). In view of non-TCELs, the highest absolute sensitivity (Sa-max) of glass ceramics was 12.21% K-1 (@698 K). These findings demonstrate that the as-prepared glass ceramic can be expected to be suitable for optical temperature sensing applications.