Children and adolescents in special education have complex medical, neurodevelopmental, and psychological needs that require coordinated, multidisciplinary care. Osteopathic family physicians (OFPs), with their holistic, whole-person approach, are uniquely positioned to lead this care by integrating medical, behavioral, and social supports. This review summarizes current prevalence data for common chronic conditions (asthma, diabetes, epilepsy), acute illnesses (allergic reactions, infections), and neurodevelopmental disorders such as attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). It also addresses the high rates of psychological concerns, including anxiety, depression, and behavioral disorders, often comorbid with neurodevelopmental conditions. Evidence-based strategies for diagnosis and management are presented alongside a review of family-centered resources—IDEA, Medicaid/CHIP, vocational rehabilitation, special needs trusts—and school-based supports such as individualized education programs (IEPs) and positive behavioral interventions and supports (PBIS). Emphasis is placed on long-term care planning, including legal and financial considerations (guardianship, special needs trusts), transition to adult services, community integration, and sustained care coordination. Early identification, continuous advocacy, and seamless collaboration among healthcare providers, educators, therapists, and family support networks are critical to optimizing health outcomes and quality of life for this vulnerable population.
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