Introduction Panchakarma therapy is designed to eliminate the vitiated doshas through the nearest route and maintain a state of equilibrium. Nasya karma is an important therapeutic module in the Panchakarma. Scalp psoriasis relates to a condition called Darunaka in Ayurveda having pradhanata of kapha and vata dosha featuring itching hair fall numbness and dryness and scaling of the skin over the scalp region. Nasya has been selected as the main line of treatment for Darunaka seborrheic dermatitis as the sthana of the disease is Urdhwa Jatru above the neck. Shiro Abhyanga complete massage of the head neck and shoulder regions is also performed as dryness and itching are the common features of scalp psoriasis.Objectives To compare the effects of two different courses ndash Navana Nasya and Shiro Abhyanga ndash in scalp psoriasis treatment.Study Design A comparative clinical study was performed on 40 males and females in the 16-70 years age group who were randomly assigned to 2 groups - Group A and Group B. Group A underwent Nasya karma for seven continuous days and Group B received the same treatment in seven sittings with a gap of two days. Shiro Abhyanga was performed for 21 days on both the groups. Bhringarajadi taila was administered for both the therapies. The patients were assessed before the initiation and at the end of treatment. The observations and results were analyzed based on the area involved itching scaling erythema thickness and Psoriasis Area and Severity Index PASI score.Results Both forms of treatment showed highly significant changes in scalp psoriasis. However Group B showed statistically significant improvement in the scaling and thickness when compared to Group A. Additionally Group B was more convenient and effective clinically.nbsp