Group Of Mexican Women Research Articles

HIGH BLOOD PRESSURE IN WOMEN ACCORDING TO CARDIOVASCULAR RISK FACTORS AND ANTIHYPERTENSIVE TREATMENT: THE IMPORTANCE OF DETECTION

Objective: To evaluate the relationship between the presence of high blood pressure in a group of Mexican women, according to cardiovascular risk factors and antihypertensive treatment. Design and method: We analyzed the data of 341 women, > 18 years, with multiple risk factors, who attended cardiovascular imaging department. Cardiovascular risk factors and antihypertensive treatment were analyzed. Hypertension was classified according to the European Society of Cardiology (ESC) Guidelines (SBP >140 mmHg and DBP > 90 mmHg). Statistical analysis: SPSS v23; descriptive and comparative analysis with chi-square, confidence level 95%. Results: Mean age 58±15.6; Cardiovascular risk factors: hypertension 201 (58.9%), diabetes126 (37%), 136 (40%) dyslipidemia, tobacco use 97 (27.8%), chronic kidney disease 63 (18.5%); 248 (72.7%) were menopausal. A total of 198 (58.1%) patients with hypertension were on pharmacological treatment: 88 (44.5%) with monotherapy, 85 (42.9%) on dual therapy, and 25 (12.6%) with multiple therapies; (46.4%) were non-controlled. There were 143 (41.9%) patients, that were detected and classified as hypertensive according to European Society of Hypertension guidelines: Grade 1 88 (61.5%), Grade 2, 22 (15.38%), Grade 3, 6 (4.1%). A relationship between hypertensive women, kidney disease (47.6%, p = 0.001), and menopause was found (37.9%, p: 0.039). Conclusions: Hypertension is an important cardiovascular risk factor in women. Most are associated with others risk factors; more than fifty percent were on multiple therapy and uncontrolled. It is necessary to optimize antihypertensive treatment to improve hypertension control, especially in postmenopausal women and with kidney disease. Screening also must be improved to prevent future complications.

Prevention of breast cancer in the general population: Is it a cultural issue?

e22511 Background: Since 2006 breast cancer has been the main cause of cancer mortality in Mexican women representing 14% of cancer related deaths. In Mexico the incidence and mortality of breast cancer have increased in recent decades and will continue to rise. Despite the vast information media on the prevention of this cancer the diagnosis of between 50 - 70% of cases is carried out in advanced stages probably due to a limited understanding of knowledge and practices of early prevention for breast cancer. Methods: The study universe was 375 Mexican women between 30 - 58 years of age of any socioeconomic level in the open population of Orizaba Veracruz who signed the informed consent form. The socioeconomic level was determined with the index of the Asociación Mexicana de Inteligencia de Mercado y Opinión Pública. The level of knowledge was determined by means of a 10 question survey type test on knowledge and practices of early prevention of breast cancer, based on Norma Oficial Mexicana 041. Period: March-May 2019. Results: Of the 375 women, 145-38.7% corresponded to high, 109-29.1% to medium high, 62-16.5% to medium, 26-6.9% to medium low, 17-4.5% to upper low and 16-4.3% to low socioeconomic levels, respectively. Mean age: 43.17 +7.82. Levels of knowledge were high in 28-7.5%, medium in 211-56.3%, low in 134-35.7% and null in 2-0.5% women respectively. 360-96% received information about prevention of breast cancer . 248-66% knew 1 to 3 risk factors, 101-27% >4 risk factors and 26-7% no risk factors. 338-90% know where to go in case of finding an abnormality in their breasts. 272-72% know the age at which they should perform the first self examination, 76-20% know the age at which they should go with trained health personnel for the exploration of their breasts. 233-62% know the age at which the first mammogram should be performed, 91-24% know the age at which the last mammogram should be performed and 8-22% know the frequency of time that a mammogram should be performed. 247-65% have had the 2 corresponding mammograms in the last 4 years. We recognize that this study may have as a limitation that the sample of patients comprises a specific group of Mexican women, however, due to its heterogeneity, its demographic characteristics could be applicable to Mexico and Latin America. Conclusions: Knowledge of the prevention of breast cancer is medium observing a direct relationship between the socioeconomic level and the level of knowledge. Effective communication between health professionals and women must take into account the socioeconomic level of patients in order to achieve a greater understanding of it and potentially reduce the incidence and mortality rate of breast cancer. It is important not to stop emphasizing the importance of continuing medical education and patient education programs for the early detection of breast cancer by patients and first contact physicians as well as primary and secondary prevention strategies which are vitally important in developing countries.

Risk Factors Associated with Breast Cancer

Background: It is reported that genetic and hereditary-familial risk factors for breast cancer contribute 5% and the majority are related to the reproductive life of women. Objective: it has the purpose of determining if the factors considered as risk factors are associated with breast cancer in a group of Mexican women. Material and Methods: A retrospective, observational and descriptive study was carried out in 162 women with breast cancer for 3 years (2002-2004) at the Hospital Juárez de México to determine if the usual risk factors are related to breast cancer. The descriptive analysis included localization and dispersion measures, as well as a graphical analysis using bar diagrams. Results: In the sample of 162 women with breast cancer, the age range at the time of breast cancer diagnosis was from 27 to 78 years (mean of 47.60, standard deviation of 13.09); early menarche only appeared in 12.3% (n=20). The mean age of the first pregnancy was 22 years and of menopause at 51 years of age; 72.2% lactated (n=117) and 45.1% did so for more than 6 months (n=73); the menstrual pattern disorder appeared in 22.8% of cases (n=37); Menopausal hormone therapy was previously used in 19.8% (n=32). The hereditary-family history of breast cancer appeared in 14.2% of the cases (n=23). It seems to be correlated with the fact that in patients with nulliparity, alcoholism and the absence of breastfeeding, breast cancer occurs at an early age (< 45 years) and the risk factor that is related to breast cancer is overweight and obesity with 54.26% and 17.11% respectively (average of 28.00, standard deviation of 3.032). Conclusion: no correlation was found between risk factors considered common for breast cancer; only overweight and obesity were related to its development, further research is required to confirm whether this correlation occurs in other countries.

Vitamin D Deficiency in Mexican Pregnant Women: Is Supplementation with ≤400 IU/day Enough?

Controversy remains surrounding vitamin D routine supplementation in healthy pregnancy, and the doses are unclear. The aim of this study was to describe maternal vitamin D status throughout pregnancy in a group of Mexican women and evaluate the effect of frequently prescribed doses of vitamin D3 on longitudinal 25-OH-D concentrations, adjusting for obesity, season, and other factors. We conducted a cohort study (Instituto Nacional de Perinatología-INPer) (2017–2020)) of healthy pregnant women without complications. Pregestational overweight/obesity (body mass index ≥ 25), vitamin D3 supplementation (prescribed by physician; 0–250, 250–400, and >400 IU/day), and serum 25-OH-D concentrations (ELISA) were evaluated in each trimester of pregnancy. Vitamin D deficiency or insufficiency was computed (<20 and <30 ng/mL, respectively). We studied 141 adult women; 58.5% had pregestational obesity or overweight. In the first trimester, 45.8% of the women were supplemented with vitamin D3; 51.4% had vitamin D insufficiency and 37.3%, deficiency. In the third trimester, 75.4% of the women were supplemented, and 20% of them still had deficiency. The final general mixed linear model showed that 25-OH-D significantly increased throughout pregnancy (p < 0.001); the highest increase was observed in the third trimester in women with doses >400 IU/day of vitamin D3 (+4 ng/mL, 95% CI: 1.72–8.11 ng/mL). In winter/autumn, 25-OH-D concentrations were also lower (p ≤ 0.05). In this group of pregnant Mexican women, the prevalence of vitamin D deficiency and insufficiency was high. A higher increase in 25-OH-D concentrations during pregnancy was observed when the women were supplemented with >400 IU/day. Common supplementation doses of 250–400 IU/day were insufficient for achieving an adequate maternal vitamin D status.

Ethics of care, emotional work, and collective action of solidarity: the Patronas in Mexico

In this paper, we examine the mobilization of the Patronas, a group of Mexican women who have fed thousands of Central American migrants over the past two decades. We argue that the Patronas’ work of feeding and caring for migrants goes beyond essentializing these women’s work as just housewives, mothers, and caregivers. Furthermore, we assert that through these care activities, the Patronas exert a feminist ethic of care that is understood as a set of practices based on trust, reciprocity, and solidarity. The Patronas’ praxis of caring for the migrants resonates with people and attracts hundreds of volunteers to join these women’s emotional and nurturing work leading these women and volunteers to participate in a political practice of solidarity. In this paper, we articulate three key findings: (1) the interplay between the Patronas’ emotional work and the ethics of care, (2) the emergence of a collective act of solidarity around the Patronas’ caring work that leads hundreds of volunteers to visit these women and join them, and (3) the kitchen as a place where the collective act of solidarity begins and where the Patronas experience their personal transformation. Drawing on ethnographic fieldwork, this study contributes to further our understanding of the interplay between Latin American women’s participation in social movements, emotional work in these movements, and the ethics of care.

Análisis con perspectiva de género sobre percepción y prácticas en enfermedad coronaria en mujeres en el norte de México

To analyze the perception of coronary risk and health care practices in a group of Mexican women, from a gendered perspective. Mixed methods: survey of 140 women; nine in-depth interviews to women with coronary disease; eight semi-structured interviews to physicians. proportions contrast for quantitative data; and procedures of grounded theory for qualitative information. More than 50% of women don't know their coronary risk and how to reduce it. Despite having information about heart disease, vulnerable women with chest pain sought medical attendance less than non-vulnerable women (p=0.0l); and are blamed by physicians. Women consider they lack sufficient information about how to reduce the risk of coronary disease, and blame themselves when ill. There are vulnerability conditions in women that modulate a low perception of their being at risk, and the scarcity of health care practices.

Assessment of vascular function in Mexican women exposed to polycyclic aromatic hydrocarbons from wood smoke

The use of solid fuels for cooking and heating is likely to be the largest source of indoor air pollution on a global scale; these fuels emit substantial amounts of toxic pollutants such as polycyclic aromatic hydrocarbons (PAHs) when used in simple cooking stoves (such as open “three-stone” fires). Moreover, indoor air pollution from biomass fuels is considered an important risk factor for human health. The aim of this study was to evaluate the relationship between exposure to PAHs from wood smoke and vascular dysfunction; in a group of Mexican women that use biomass combustion as their main energy source inside their homes. We used 1-hydroxypyrene (1-OHP) as an exposure biomarker to PAHs and it was assessed using high performance liquid chromatography. The endothelium-dependent vasodilation was assessed through a vascular reactivity compression test performed with a pneumatic cuff under visualization of the brachial artery using high resolution ultrasonography (HRU). Assessment of the carotid intima-media thickness (CIMT) was used as an atherosclerosis biomarker (also assessed using HRU); and clinical parameters such as anthropometry, blood pressure, glucose, triglycerides, total cholesterol, HDL cholesterol, LDL cholesterol, among others were also evaluated. The mean concentration of urinary 1-OHP found in exposed women was 0.46±0.32μmol/mol Cr (range: 0.086–1.23μmol/mol Cr). Moreover, vascular dysfunction (diminished endothelium dependent vasodilation) was found in 45% of the women participating in the study. Association between vascular function and 1-OHP levels was found to be significant through a logistic regression analysis (p=0.034; r2=0.1329). Furthermore, no association between CIMT and clinical parameters, urinary 1-OHP levels or vascular dysfunction was found. Therefore, with the information obtained in this study, we advocate for the need to implement programs to reduce the risk of exposure to PAHs in communities that use biomass fuels as a main energy source.

Association of consumption of carbonated beverages and decalcification in woman on reproductive and non-reproductive age of Mexico City

There is not enough information about carbonated beverages (CB) consumption in Mexican women and its association with bone mineral density (BMD). The objective was to identify the association of CB consumption with BMD in two groups of Mexican women. Transversal study with 328 women in reproductive age (WRA) and not reproductive (WNRA) with diet and anthropometric evaluation and BMD. Mean age of 18.7 years in WRA and 47 in WNRA. Energy adequacy percentage was lower in WNRA (98 ± 28% vs 144 ± 55) (p = 0.001), calcium intake was < 700 mg/day in women with osteopenia of both groups and median consumption of CB was higher in WRA, with 200 mL/day (0-462) vs 0 (0-250) in WNRA (p = 0.001), WRA with osteopenia drank 500 mL/day (253-750) of CB vs 100 (0-200) in who had not (p = 0.001). Anthropometric parameters were higher in WNRA (p =?0.002) and femoral neck BMD was lower (1.031 ± 0.14 vs 1.107 ± 0.10) (p = 0.001) and higher in L2-L4 (1.114 ± 0.13 vs 1.003 ± 0.09) (p = 0.001) in WRA. Variables associated with risk of osteopenia: drink CB (OR 11.186, p = 0.001), consuming < 700 mg of calcium (OR 5.774, p = 0.001) and dinner no milk (OR 1.942, p = 0.042). To drink CB increases risk of osteopenia in both groups, WRA drink more CB than WNRA and they will have high probability of fractures younger.

Los distintos tipos de subversión femenina presentados en Recuerdos del porvenir

The novel Recuerdos del Porvenir (1963) by Mexican author Elena Garro depicts in an innovative way the military occupation of Ixtepec, that happened after the Mexican Revolution and the subsequent Cristero War of 1920s. Through a collective narrator, the writer gives voice to subaltern groups of population who are forgotten or misrepresented in Revolutionary novels written by Garro’s masculine counterparts. Most importantly, her narrative is replete with examples of feminine subversion toward the status quo and the locus of enunciation. At the same time, Garro breaks with the canon by changing the focus to the female protagonists and by introducing in her novel the Magical Realism to illustrate the female interiority and sensitivity, as well as her personal vision and interpretation of the world. In her maximum expression of rebellion, Garro shows a variety of groups of Mexican women who tried very hard to reach an authentic identity, but the patriarchal society thwarted their plans. As a result, the woman stumbles and fails to contribute to the cause, sometimes becoming a mere traitor and then also a simple witness of the injustice. Many times, she represents main transmitting and defending agent of the same chauvinistic culture that has subjugated her.

Exposure to Phthalates During Pregnancy in Mexican Women

ISEE-830 Objective: To assess exposure to phthalates during pregnancy in a group of Mexican women. Materials and Methods: Prospective cohort of 77 women in the State of Mexico. Urinary levels of 3 phthalate primary metabolites during the first, second, and third trimesters of pregnancy were measured by GCMS. Results: The geometric mean and 95% CI for the studied metabolites were monobutyl phthalate (MBP) 20.38 (15.35–27.09), monoethylhexyl phthalate (MEHP) 13.43 (8.93–20.20), and monoethyl phthalate (MEP) 52.47 (39.88–69.04) μg/g of creatinine. No significant trends of the studied metabolites were detected during pregnancy periods. Less-educated women presented higher concentrations of MBP. Women residents in the industrialized zone present higher levels of MEHP and MEP. The consumption of bottled beverages was associated with MBP and MEHP. Women who used nonregistered brand products to storage food or to heat it in the microware oven presented higher levels and MBP and MEP. Conclusions: Exposure to phthalates is constant during pregnancy and could be a risk to the newborn. To integrate public health interventions, a better exploration of the potential exposure sources and effects at a regional level is required.

Assessing phytochemical intake in a group of Mexican women

Identify the content of selected phytochemicals (PHYs) in Mexican foods and evaluate the reliability of a food frequency questionnaire (FFQ) in assessing PHYs intake among Mexican women. Values for PHYs content were obtained from four different data sets. PHYs intake was assessed in 50 women of reproductive age enrolled in a longitudinal cohort study. Values were obtained from a FFQ administered twice, one year apart in order to evaluate its reliability. Selected PHYs included flavonol (FOL), flavones (FES), flavanol (FAL), secoisolariciresinol (SE), matairesinol (MA), lariciresinol (LA), pinoresinol (PI), cynamic acid (CA) and coumestrol (CU). Daily PHYs intake ranged from 1.3 microg +/- 0.9 for MA to 116.3 +/- 43.8 mg for CA. The adjusted correlation coefficients ranged from 0.17 for FAL to 0.47 for LA. Pinto beans, oranges, hot sauce, broccoli, apples and onions were the main sources of the selected PHYs daily intake. The results of this study contribute to our understanding of the consumption of PHYs in the Mexican diet, and would help evaluate their potential health impact.

Clinical follow up of Mexican women with early onset of breast cancer and mutations in the BRCA1 and BRCA2 genes

This study describes the presence of mutations in BRCA1 and BRCA2 genes in a group of Mexican women and the clinical evolution of early onset breast cancer (EOBC). A prospective hospital-based study was performed in a sample of 22 women with EOBC (7 in clinical stage IIA, 8 in IIB, and 7 in IIIA). The patients attended a tertiary care hospital in northeastern Mexico in 1997 and were followed up over a 5-year period. Molecular analysis included: 1) a mutation screening by heteroduplex analysis (HA) of BRCA1 and BRCA2 genes and 2) a sequence analysis. Of 22 patients, 14 (63.6%) showed a variant band detected by heteroduplex analysis of the BRCA1 and BRCA2 genes: 8 polymorphisms, 4 mutations of uncertain significance, and 2 novel truncated protein mutations, one in BRCAI (exon 11, 3587delT) and the other in the BRCA2 gene (exon 11, 2664InsA). These findings support future studies to determine the significance and impact of the genetic factor in this Mexican women population.

Plasma total homocysteine in Mexican rural and urban women fed typical model diets

Objective The purpose of the present work was to determine the fasting plasma total homocysteine (tHcy) levels and the time-course response of tHcy concentrations after the consumption of urban and rural Mexican model diets in two groups of Mexican women from urban and rural areas. Methods Thirty-three adult women (age range = 18–49 y) were studied. Fifteen women were from a rural community in the state of Mexico. The other 18 were from cities and consumed diets that regularly included an important amount of animal foods. The study was designed as a two-period crossover study in which subjects consumed the model urban or rural diet in a 2-wk interval. Seven milliliters of venous blood was drawn before ingestion of experimental diets (basal) to measure total cholesterol, high-density lipoprotein cholesterol, triacylglycerol, tHcy, folate, vitamin B12, and methionine. Blood samples were then obtained 30, 60, 90, 180, and 240 min after the beginning of meal consumption. Results The rural and urban groups showed similar concentrations of tHcy 4 h after meal consumption and after fasting. However, the urban and rural groups had higher methionine plasma concentrations after the urban diet than after the rural diet. In contrast, there was no significant difference in methionine plasma levels between the rural and urban groups with each diet. Those women with low tHcy concentrations maintained those values over the study period, and those with high tHcy concentrations maintained those values. There was no significant difference in tHcy concentrations due to consumption of the two diets ( P = 0.31) or the interaction between population and diet ( P = 0.84). However, there was a significant difference in the concentration of tHcy between the rural (8.73 ± 0.17 μM/L) and the urban (9.27 ± 0.13 μM/L) populations ( P = 0.01). In both groups, average tHcy concentration was in the normal range. In both populations, the nutrition status for folate and vitamin B12 was adequate, although plasma folate concentration was significantly lower in the rural population than in the urban population ( P < 0.01). Plasma vitamin B12 concentrations were similar in both groups. No subject had low plasma vitamin B12. Conclusions Plasma tHcy concentrations in rural and urban Mexican women were within the range considered adequate; however, urban women showed significant higher concentrations than did rural women independently of the consumed diet and the plasma methionine concentration. These results indicated that there is no short-term variation in plasma tHcy due to the consumption of rural or urban diets.

Menstrual cycle length disorders in 18- to 40-y-old obese women

Objective The objective of this study was to measure the relation between menstrual cycle length disorders and degree of obesity. Methods We enrolled 120 obese patients ages 18 to 40 y from an outpatient obesity clinic in a cross-sectional study. Patients with polycystic ovarian syndrome were excluded. Obesity was classified in five grades by relative weight. Waist-to-hip ratio was measured and comorbidities were assessed in each patient. Patients were asked to record menstrual cycle characteristics for 3 mo. Logistic regression analysis was performed, with age and type 2 diabetes as confounding variables. The patients’ mean age was 29.9 ± 6.4 y, the mean relative weight was 159.2 ± 26.6%, and the mean waist-to-hip ratio was 0.84 ± 0.1. Results Twenty-two (18.3%) patients had oligomenorrhea and 14 (11.7%) had amenorrhea. The risks for amenorrhea and oligomenorrhea were increased twofold by each unit increase of obesity grade. The odds ratio by waist-to-hip ratio tertile was not statistically significant. Type 2 diabetes and glucose intolerance were statistically significantly associated with amenorrhea and oligomenorrhea. Conclusions Higher obesity grades were associated with higher probabilities of menstrual cycle disturbances such as amenorrhea and oligomenorrhea in this group of Mexican women.

Factores asociados al papilomavirus humano en mujeres Mexicanas

El objetivo de este estudio es determinar las variables epidemiológicas asociadas a la infección por papilomavirus humano en un grupo de mujeres mexicanas. En un estudio prospectivo, transversal y comparativo, se estudiaron 470 mujeres que acudieron para valoración citológica y colposcópica; previo al examen ginecológico se les realizó una entrevista en la cual se consignó la ficha de identidad, historia reproductiva, anticonceptiva, sexual, tabaquismo pasivo y activo. El diagnóstico de papilomavirus se realizó por citología y colposcopia. Las mujeres infectadas fueron más jóvenes y tuvieron menos embarazos y partos que las mujeres sanas. En el análisis multivariado la edad de las pacientes y la edad del primer embarazo resultaron ser factores protectores contra la infección. A diferencia de otras investigaciones, este estudio no encontró ninguna asociación entre la infección con papilomavirus y la conducta sexual.