Google Web Research Articles

TA2Viewer: A web-based browser for Terminologia Anatomica and online anatomical knowledge.

TA2Viewer is an open-access, web-based application and database for browsing anatomical terms and associated medical information on a computer or mobile device (https://ta2viewer.openanatomy.org/). It incorporates the official digital version of the second edition of Terminologia Anatomica (TA2) as published by the Federative International Programme for Anatomical Terminology (FIPAT), and adopted by the International Federation of Associations of Anatomists (IFAA) and other associations. It provides a dynamic and interactive view of the Latin and English nomenclatures. The organizational hierarchy of the terminology can be navigated by using a scrollable, expandable, and collapsible structured listing. Interactive search includes the official TA2 terms, synonyms, and related terms. TA2Viewer also uses TA2 term information to provide convenient access to other online resources, including Google web and image searches, PubMed, and Radiopaedia. Using cross-references from Wikidata, which were provided by the Wikipedia community, TA2Viewer offers links to Wikipedia, UBERON, UMLS, FMA, MeSH, NeuroNames, the public domain 20th edition of Gray's Anatomy, and other data sources. In addition, it can optionally use unofficial synonyms from Wikidata to provide multilingual term searches in hundreds of languages. By leveraging TA2, TA2Viewer provides free access to a curated anatomical nomenclature and serves as an index of online anatomical knowledge.

User Interface Optimization Using Human Centered Design Method to Improve Website Usability (Case Study: Entrance Cilacap)

A good user interface design on a website will make users feel at home using the website. On the contrary, a bad user interface will make users quickly leave the site or bounce rate. User involvement in the system development process will have a positive and significant impact on satisfaction with a system. The objective of this study is to obtain a new user interface that can overcome the usability problems in the web design of the Cilacap Entrance. To meet user needs, this study uses the human centered design (HCD) method for web redesign. User identification and interviews were conducted to obtain user context data. While user personas are used to determine user needs. In addition, A/B testing was used by applying the results of heatmap analysis and data from Google Analytics and Google Web Console to compare the results before and after the interface redesign. The results showed an increase in the number of users, longer visits, more content exploration, and high activity on the site. This means that the redesigned interface was successful in improving user experience, increasing user activity, and maintaining user interest in the Cilacap Entrance website.

The Microbial Role in Allergy: A Comprehensive Review

Background: The rise in allergic diseases in Western industrial nations has been paralleled by an increased understanding of the intricate relationship between microbial exposure and immune system responses. The hygiene hypothesis suggests a link between reduced exposure to infectious agents and an increase in allergies, emphasizing the need for a deeper investigation into the roles of various microbes in allergic reactions. Objective: This review aims to elucidate the complex mechanisms underlying allergic reactions, specifically focusing on the roles of parasites, bacteria, fungi, and viruses. It seeks to explore the potential of microbial exposure as both a protective and pathogenic factor in the development of allergies, with an eye towards informing future therapeutic strategies. Methods: An extensive literature review was conducted using databases such as Google Scholar, Scopus, PubMed, and Web of Sciences, focusing on studies published up to March 2024. The review synthesized findings on the impact of microbial exposure on allergic diseases, examining the roles of specific microbes, their interaction with the immune system, and the implications for allergic responses. Results: The review highlights the dual nature of microbial exposure in allergies, with some microbes offering protection against allergic diseases through the modulation of immune responses, while others exacerbate allergic conditions. Notably, probiotics and certain parasitic infections demonstrate potential in modulating the immune system to prevent or reduce allergic responses. Conversely, specific bacterial, fungal, and viral exposures are linked to the exacerbation of allergic diseases. Conclusion: Understanding the complex relationship between microbial exposure and allergic diseases is crucial for developing novel therapeutic and preventive strategies. This review underscores the potential of targeted microbial management in modulating immune responses to allergens, suggesting a promising avenue for reducing the global burden of allergic diseases.

The Application of Foot Reflexology for Anxiety and Pain Management in Women's Childbirth: A Literature Review

Context: Uncontrolled childbirth anxiety (CA) and labor pain (LP) may cause negative consequences for the mother during subsequent deliveries. This study aimed to evaluate the effect of foot reflexology (F-REFL) on reducing LP and CA during childbirth in the form of a review study. Evidence Acquisition: In this literature review, the findings were collected by evaluating the results of previous similar studies in the last three decades. The most important and common medical subject headings (MeSH) terms related to the topic under discussion were identified to conduct this study. Then, the most relevant studies were searched, and 226 studies were identified at this stage by searching them in the most reliable and essential international databases, including Google Scholar, Scopus, PubMed, and Web of Science. Considering the inclusion and exclusion criteria, 26 studies were identified to extract the results. Results: Most of the previous research studies were clinical trials, and their findings showed that F-REFL significantly reduces LP and CA. Conclusions: Foot reflexology has been shown to reduce LP and CA, making it an easy, cheap, and noninvasive method to reduce cesareans. Implementing this method is simple and does not require specialized personnel, and midwives can efficiently perform for mothers during childbirth. Additionally, reducing LP and CA experienced during birth through F-REFL improves women's positive birth experiences and protects postpartum mental health.

An Appraisal of the Progress in Utilizing Radiosondes and Satellites for Monitoring Upper Air Temperature Profiles

Upper air temperature measurements are critical for understanding weather patterns, boundary-layer processes, climate change, and the validation of space-based observations. However, there have been growing concerns over data discrepancies, the lack of homogeneity, biases, and discontinuities associated with historical climate data records obtained using these technologies. Consequently, this article reviews the progress of utilizing radiosondes and space-based instruments for obtaining upper air temperature records. A systematic review process was performed and focused on papers published between 2000 and 2023. A total of 74,899 publications were retrieved from the Google Scholar, Scopus, and Web of Science databases using a title/abstract/keyword search query. After rigorous screening processes using relevant keywords and the elimination of duplicates, only 599 papers were considered. The papers were subjected to thematic and bibliometric analysis to comprehensively outline the progress, gaps, challenges, and opportunities related to the utilization of radiosonde and space-based instruments for monitoring upper air temperature. The results show that in situ radiosonde measurements and satellite sensors have improved significantly over the past few decades. Recent advances in the bias, uncertainty, and homogeneity correction algorithms (e.g., machine learning approaches) for enhancing upper air temperature observations present great potential in improving numerical weather forecasting, atmospheric boundary studies, satellite data validation, and climate change research.

GPT-4 as a Source of Patient Information for Anterior Cervical Discectomy and Fusion: A Comparative Analysis Against Google Web Search.

Comparative study. This study aims to compare Google and GPT-4 in terms of (1) question types, (2) response readability, (3) source quality, and (4) numerical response accuracy for the top 10 most frequently asked questions (FAQs) about anterior cervical discectomy and fusion (ACDF). "Anterior cervical discectomy and fusion" was searched on Google and GPT-4 on December 18, 2023. Top 10 FAQs were classified according to the Rothwell system. Source quality was evaluated using JAMA benchmark criteria and readability was assessed using Flesch Reading Ease and Flesch-Kincaid grade level. Differences in JAMA scores, Flesch-Kincaid grade level, Flesch Reading Ease, and word count between platforms were analyzed using Student's t-tests. Statistical significance was set at the .05 level. Frequently asked questions from Google were varied, while GPT-4 focused on technical details and indications/management. GPT-4 showed a higher Flesch-Kincaid grade level (12.96 vs 9.28, P = .003), lower Flesch Reading Ease score (37.07 vs 54.85, P = .005), and higher JAMA scores for source quality (3.333 vs 1.800, P = .016). Numerically, 6 out of 10 responses varied between platforms, with GPT-4 providing broader recovery timelines for ACDF. This study demonstrates GPT-4's ability to elevate patient education by providing high-quality, diverse information tailored to those with advanced literacy levels. As AI technology evolves, refining these tools for accuracy and user-friendliness remains crucial, catering to patients' varying literacy levels and information needs in spine surgery.

Apoptosis Response in Acute Lymphoblastic Leukemia Cells after Methotrexate Treatment-A Systematic Review

Background: Acute lymphoblastic leukemia (ALL) is a malignancy characterized by the overproduction of immature white blood cells in the bone marrow. Methotrexate (MTX) is a cornerstone chemotherapy agent utilized in ALL treatment due to its ability to induce apoptosis in cancerous cells. MTX’s action involves inhibiting dihydrofolate reductase (DHFR), leading to impaired DNA and RNA synthesis, yet resistance to MTX and its exact apoptotic mechanisms remain areas of ongoing research. Objective: This systematic review aims to elucidate the mechanisms by which MTX induces apoptosis in ALL cells and to assess the clinical implications of these findings for improving therapeutic strategies. Methods: Adhering to PRISMA guidelines, databases including Google Scholar, Embase, PubMed, and Web of Science were searched for studies published between 2000 and 2023. Studies were included if they involved MTX treatment of ALL cell lines and assessed apoptosis. Critical Appraisal Skills Programme (CASP) tools were used for quality assessment. Data extraction and thematic analysis were employed to synthesize findings. Results: Twenty-six studies met the inclusion criteria. Key mechanisms of MTX-induced apoptosis included disruption of mitochondrial membrane potential, activation of the JNK signaling pathway, modulation of BCL-2 family proteins, and interference with folate metabolism. Resistance mechanisms and the therapeutic potential of MTX polyglutamates were also identified. Conclusion: MTX induces apoptosis in ALL cells through multiple pathways, primarily by disrupting folate metabolism and mitochondrial function. The findings reinforce the necessity for personalized approaches in MTX-based therapy, considering the emerging resistance patterns, and highlight the potential of MTX polyglutamates in enhancing treatment efficacy.

Under utilization of long-lasting insecticidal nets (LLINs) is challenging malaria elimination program in Ethiopia: a systematic review and meta-analysis

BackgroundMalaria is one of the most common causes of morbidity and mortality in developing countries including Ethiopia. Mass distribution of insecticide-treated nets and indoor residual spray for high malaria risk groups are the major prevention measures in different countries. Achievement of the malaria elimination plan is highly determined by the level of effective utilization of intervention measures. However, there is scarce information showing the national level of insecticide-treated nets utilization.ObjectiveTo estimate the pooled prevalence of insecticide-treated nets utilization in Ethiopia, 2023.MethodA Systematic Review and Meta-analysis employed to assess the utilization of long-lasting insecticidal nets in Ethiopia. Published articles were searched from Google Scholar, PubMed, Web Sciences, CINAHIL, EMBASE, and Scopus. The collected articles were screened for data extraction and further analysis using preferred reporting items for systematic review and meta-analysis (PRISMA) flow chart. The quality of each study was assessed using the Jonna Briggs Institute (JBI) checklist. The data were extracted using Microsoft Excel and exported to STATA version 17.0 for analysis. The overall pooled prevalence of long-lasting insecticidal nets utilization was determined using a random effects model.ResultOut of 1657 articles reviewed, only 21 of them were eligible for final analysis. All of the included studies were used to estimate the pooled prevalence of long-lasting insecticidal net utilization. The point prevalence of LLIN utilization ranged from 14.23 to 91.9%. The Meta-analysis estimated that the overall pooled prevalence of insecticidal nets utilization among all study participants in Ethiopia was 56.26% (95%CI: 44.04–68.48%). Subgroup analysis revealed that insecticidal nets utilization was relatively highest in the Amhara region [63.0, 95%CI (37.0–89.0%)] and during 2020–2023 [61, 95% CI (53.0–69.0%)].ConclusionLong-lasting insecticidal nets utilization in Ethiopia is lower than the national target plan. Hence, it needs extra follow-up and intervention to enhance its utilization.

Impact of Auditors' Attributes on the Identification of Creative Accounting Practices in Pakistan

Accounting creativity is the process of changing financial information beyond the limits of accounting norms to provide an improved overview of a company's financial status and performance. The current study investigates creative accounting practices in Pakistan, focusing on auditors' competency, integrity, independence, and ethics in detecting creative accounting practices, thereby enhancing financial transparency in the business context. The data for the study were collected via a questionnaire using a Google Web form shared with 120 auditors from audit organizations working in Pakistan. The results of multiple regression analysis revealed that auditor competency, honesty, independence, and ethics have a significant influence on detecting creative accounting practices followed by accountants to manipulate the financial position and performance of their organizations. The results of this study hold significant practical implications for auditors, regulators (such as the SECP), and policymakers. Future research may be focused on assessing the efficacy of audit committees in overseeing companies' stakeholder reporting and their management of ethical and sustainability concerns. This study contributes to the literature by exploring the realm of accounting creativity in Pakistan, specifically delving into auditors' capabilities and integrity in identifying creative accounting practices. It sheds light on the significance of auditors' competency, honesty, and ethical considerations in uncovering manipulative financial reporting strategies employed by accountants.

Efforts Undertaken by Several ASEAN Countries to Address Childhood and Adolescent Obesity in School-Based Programs: A Systematic Review

Background: Childhood and adolescent obesity is on the rise in Southeast Asia. Necessitating stronger actions from ASEAN governments to address this issue, because the significant financial and social welfare implications. Schools provide an effective platform for targeted interventions among children and adolescent groups. Objectives: This study provides an overview of school-based nutrition interventions implemented in ASEAN countries to address childhood and adolescent obesity. Methods: A literature review was conducted by searching multiple databases (Google Scholar, PubMed, ProQuest, ScienceDirect, and Web of Science) between April 1 and May 1, 2023. The search included computer-based searches and manual search in relevant journals. The articles considered were limited to publications from the past 10 years. Discussion: School-based nutrition interventions in ASEAN countries require further development, with attention to key factors such as intervention duration, sample size, and family involvement. Conclusions: Urgent large-scale research is needed to evaluate the effectiveness of existing school-based nutrition programs. Integrated and effective programs require support and collaboration from families, the private sector, and the government.

Research advances in Peyronie's disease: a comprehensive review on genomics, pathways, phenotypic manifestation, and therapeutic targets.

Penile induration disease, commonly known as Peyronie's disease (PD), is a connective tissue disorder that affects the penis, leading to the development of fibrous plaques, penile curvature, and erectile dysfunction. PD is a common male reproductive system disease with a complex etiology involving multiple genes, signaling pathways, and different phenotypes. The etiology and pathogenesis of PD remain poorly understood, hindering the development of effective treatment strategies. By understanding the underlying mechanisms of PD, we can pave the way for targeted therapies and improved patient outcomes. We reviewed the epidemiology and pathophysiology of PD. We performed database searches on Google Scholar, PubMed, Medline, and Web of Science from inception to September 2023. The literature reviewed included priapism guidelines, review articles, current trial studies, and various literature related to PD. This article provides a comprehensive overview of the current research progress on the disease, focusing on its genetic factors, signaling pathways, cellular mechanisms, phenotypic manifestations, and therapeutic targets. It can help identify individuals at higher risk, aid in early detection and intervention, and provide insights into fibrosis and tissue remodeling. It can also reveal potential therapeutic targets, guide accurate diagnoses and treatment strategies, and address the impact of the disease on patients' quality of life. By integrating insights from genomics, molecular pathways, clinical phenotypes, and therapeutic potentials, our research aims to achieve a deeper and more comprehensive understanding of PD, propelling the field toward innovative strategies that enhance the lives of those affected by PD. The complex manifestations and pathogenesis of PD necessitate the use of multiple treatment methods for personalized care.

Inclusion Body Myositis in Children: Does it Exist?

Context: Sporadic inclusion body myositis (sIBM) is a rare type of juvenile idiopathic inflammatory myopathies (JIIMs). It mainly affects skeletal muscles but can also affect the skin and other organs in the body. Sporadic inclusion body myositis prevalence in children under 18 years old is very rare. Objectives: This review provides an overview of the evidence of sIBM in children, discusses the possible clinical and pathological features, and explores the proposed pathogenesis. Methods: A literature review of over 44 articles in PubMed and other medical libraries, such as Google Scholar and Web of Science, was carried out using terms such as JIIM, IBM, Inflammatory Myopathies in Children, and Inherited IBM. Two documented reports for sIBM were found, and the rest included the disease pathogenesis, prevalence of inherited IBM, and other myopathies in children. Results: This review discussed the prevalence and incidence of JIIM, in particular sIBM in children. While IBM is typically sporadic, there have been rare cases where it is familial and inherited. Genetic susceptibility factors are believed to play a role in sIBM. Most patients with sIBM are over 50 years old and experience significant weakness in the quadriceps; however, patients with inherited IBM (h-IBM) typically present earlier in adulthood with a distinct pattern of weakness. Sporadic inclusion body myositis can be misdiagnosed as other forms of myopathies, such as juvenile dermatomyositis (JDM) or limb-girdle muscular dystrophy (LGMD), during the early stages of the disease. The exact causes of sIBM are still unknown; however, environmental factors, genetic predispositions, and immune dysregulation might contribute to the pathogenesis of the disease. Conclusions: Sporadic inclusion body myositis is a rare form of JIIMs. Its early diagnosis in children can be challenging due to the presence of other coexisting diseases. Discussions have revolved around potential environmental factors, such as viral infections, specific myositis-specific antibodies (MSAs), such as anti-Ro52, and possibly certain human leukocyte antigen (HLA) haplotypes. Given the rarity of reported cases of sIBM in children, it is important to encourage further studies to better understand the underdiagnosed instances of this condition.

Role of AI in Blended Learning: A Systematic Literature Review

As blended learning moved toward a new phase during the COVID-19 pandemic, advancements in artificial intelligence (AI) technology provided opportunities to develop more diverse and dynamic blended learning. This systematic review focused on publications related to the use of AI applications in blended learning. The original studies from January 2007 to October 2023 were extracted from the Google Scholar, ERIC, and Web of Science databases. Finally, 30 empirical studies under the inclusion criteria were reviewed based on two conceptual frameworks: four key challenges of blended learning and three roles of AI. We found that AI applications have been used mainly for the online asynchronous individual learning component in blended learning; little work has been conducted on AI applications that help connect online activities with classroom-based offline activities. Many studies have identified the role of AI as a direct mediator to help control flexibility and autonomy of students in blended learning. However, abundant studies have also identified AI as a supplementary assistant using advanced learning analytics technologies that promote effective interactions with students and facilitate the learning process. Finally, the fewest number of studies have explored the role of AI as a new subject such as use as pedagogical agents or robots. Considering the advancements of generative AI technologies, we expect more research on AI in blended learning. The findings of this study suggested that future studies should guide teachers and their smart AI partner to implement blended learning more effectively.

Implement Speech Recognition and Synthesis System Using Python

Python script implements a speech recognition and synthesis system using the Speech Recognition and pyttsx3 libraries. The system allows users to speak into their microphone, recognizes the speech using Google's Web Speech API, and then speaks out the recognized text. The main program loop continuously listens for speech input, recognizes it, and then synthesizes the recognized text into speech. The loop terminates when the recognized speech is "exit". This implementation demonstrates the integration of speech recognition and synthesis capabilities in Python, showcasing their potential applications in various domains such as human-computer interaction, accessibility, and automation.

What are our patients asking Google about acromioclavicular joint injuries?—frequently asked online questions and the quality of online resources

Management of acromioclavicular (AC) joint injuries has been an ongoing source of debate, with over 150 variations of surgery described in the literature. Without a consensus on surgical technique, patients are seeking answers to common questions through internet resources. This study investigates the most common online patient questions pertaining to AC joint injuries and the quality of the websites providing information. 1) Question topics will pertain to surgical indications, pain management, and success of surgery and 2) the quality and transparency of online information are largely heterogenous. Three AC joint search queries were entered into the Google Web Search. Questions under the "People also ask" tab were expanded in order and 100 results for each query were included (300 total). Questions were categorized based on Rothwell's classification. Websites were categorized by source. Website quality was evaluated by the Journal of the American Medical Association (JAMA) Benchmark Criteria. Most questions fell into the Rothwell Fact category (48.0%). The most common question topics were surgical indications (28.0%), timeline of recovery (13.0%), and diagnosis/evaluation (12.0%). The least common question topics were anatomy/function (3.3%), evaluation of surgery (3.3%), injury comparison (1.0%), and cost (1.0%). The most common websites were medical practice (44.0%), academic (22.3%), and single surgeon personal (12.3%). The average JAMA score for all websites was 1.0 ± 1.3. Government websites had the highest JAMA score (4.0 ± 0.0) and constituted 45.8% of all websites with a score of 4/4. PubMed articles constituted 63.6% (7/11) of government website. Comparatively, medical practice websites had the lowest JAMA score (0.3 ± 0.7, range [0-3]). Online patient AC joint injury questions pertain to surgical indications, timeline of recovery, and diagnosis/evaluation. Government websites and PubMed articles provide the highest-quality sources of reliable, up-to-date information but constitute the smallest proportion of resources. In contrast, medical practice represents the most visited websites, however, recorded the lowest quality score. Physicians should utilize this information to answer frequently asked questions, guide patient expectations, and help provide and identify reliable online resources.

ChatGPT as a Source of Patient Information for Lumbar Spinal Fusion and Laminectomy: A Comparative Analysis Against Google Web Search.

Retrospective Observational Study. The objective of this study was to assess the utility of ChatGPT, an artificial intelligence chatbot, in providing patient information for lumbar spinal fusion and lumbar laminectomy in comparison with the Google search engine. ChatGPT, an artificial intelligence chatbot with seemingly unlimited functionality, may present an alternative to a Google web search for patients seeking information about medical questions. With widespread misinformation and suboptimal quality of online health information, it is imperative to assess ChatGPT as a resource for this purpose. The first 10 frequently asked questions (FAQs) related to the search terms "lumbar spinal fusion" and "lumbar laminectomy" were extracted from Google and ChatGPT. Responses to shared questions were compared regarding length and readability, using the Flesch Reading Ease score and Flesch-Kincaid Grade Level. Numerical FAQs from Google were replicated in ChatGPT. Two of 10 (20%) questions for both lumbar spinal fusion and lumbar laminectomy were asked similarly between ChatGPT and Google. Compared with Google, ChatGPT's responses were lengthier (340.0 vs. 159.3 words) and of lower readability (Flesch Reading Ease score: 34.0 vs. 58.2; Flesch-Kincaid grade level: 11.6 vs. 8.8). Subjectively, we evaluated these responses to be accurate and adequately nonspecific. Each response concluded with a recommendation to discuss further with a health care provider. Over half of the numerical questions from Google produced a varying or nonnumerical response in ChatGPT. FAQs and responses regarding lumbar spinal fusion and lumbar laminectomy were highly variable between Google and ChatGPT. While ChatGPT may be able to produce relatively accurate responses in select questions, its role remains as a supplement or starting point to a consultation with a physician, not as a replacement, and should be taken with caution until its functionality can be validated.

Security and Privacy of Wearable Wireless Sensors in Healthcare: A Systematic Review

Wearable Wireless Sensor Network (WWSN) devices are widely used in healthcare to monitor health data. However, when WWSN users transmit their data to healthcare professionals or third parties over wireless connections, they face privacy and security vulnerabilities. This paper aims to identify the unsolved privacy and security challenges in wearable sensor devices in healthcare, especially the aspects overlooked by previous research. The main research question is: What are the unsolved privacy and security challenges in wearable sensor devices in healthcare, and what are their implications for users and healthcare professionals? This systematic review employs specific keywords to search for relevant publications on bibliographic databases, including Google Scholar, Scopus, IEEE Xplore, and Web of Science. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) charts helped in screening and summarising the selected papers. The results highlight the critical areas that can make WWSNs vulnerable to security attacks. The findings examine the security and privacy issues of wearable sensor devices in cloud computing, fog computing, the Internet of Things (IoT) and the like. Many studies examine IoT due to its privacy and security challenges, especially regarding handling extensive data, using public channels, deploying advanced technologies, managing sharing policies alongside the growing number of wireless devices, and protecting data from hackers. These challenges seriously threaten the confidentiality, integrity, and availability of health data transmitted by WWSN users to healthcare professionals or third parties in cloud-based environments and IoT and are exacerbated by limited resources. The significant findings thereby focus on unresolved areas in IoT. This paper aims to safeguard against cyber-attacks on healthcare and increase users' adoption rate of WWSN devices.

Effects of Exercise on Cartilage Thickness and Chondrocytes Count: A Meta-Analysis of Pre-Clinical Randomized Controlled Trials Conducted on Rats

Background: The evidence regarding the effects of exercises on cartilage is enormous, but the literature on improving cartilage thickness and the number of chondrocytes is limited. To determine the cumulative effects of exercises on cartilage thickness and chondrocyte number by combining results from different randomized controlled trials. Methods: Using MeSH terms like "cartilage thicknesses", "exercises", "chondrocytes", and "physical training", among others, multiple searches are conducted on exercise-based management approaches on cartilage thicknesses using search engines like Google Scholar, PEDro, MEDLINE, Cochrane Library, EMBASE, and Web of Science. Results: The risk of bias assessment was performed based on the SYRCLE guidelines. The author-based judgment was performed on selection, performance, detection, attrition, reporting, and other biases. The quantitative analysis revealed that femoral cartilage thickness had increased in the exercise group (SMD=1.039, CI%= -0.64 to 2.72, p=0.225) while chondrocyte count had shown a mild increase in response to excises (SMD= -0.147, CI%= -2.161 to 1.866, p=0.883). Conclusion: It has been concluded that although exercises have a potential impact on cartilage morphology, they must be performed within adaptive threshold limits. Keywords: Exercises, Cartilage, Chondrocytes, Animal Physical Conditioning.

Remedial Education Teachers’ Competencies for Differentiated Pedagogy: Systematic Literature Review

Remedial education is implemented to help primary school students who experience difficulties mastering the 3M skills of reading, writing, and counting. This systematic literature review was conducted to review the competency of remedial education teachers for differentiated pedagogy. The study focused on competency of remedial education teachers regarding levels of knowledge, skills, and readiness to implement differentiated pedagogy. Literature was searched through Google Scholar, SCOPUS, and Web of Science and 149 articles that had been published between 2019 to 2023 were identified; of these, 12 were selected for the analysis, which used the Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) approach. The results reveal that not all studies found that remedial education teachers’ competency for differentiated pedagogy was at high levels for all three elements – knowledge, skills and readiness. The results of this study can serve as a guide and reference for teachers, the Ministry of Education, and future researchers, to improve remedial education teachers’ competency for differentiated pedagogy. Future studies should do a more in-depth exploration, by conducting a survey to review the competency of remedial education teachers for differentiated pedagogy, and the challenges they face in implementing it.

Patterns and trends in research on external public debt management

This study undertakes a comprehensive bibliometric analysis of publications pertaining to the external public debt management system. The paper aims to study the evolution of scholarly discourse surrounding the external public debt management domain, highlighting contributions, methodologies, and collaborative networks within the field. The methodology encompasses a multivariate approach, incorporating extensive searches across the three major scientometric databases: Google Scholar (PoP), Scopus (in-built Scopus tools, SciVal), and Web of Science (in-built WoS instruments). The bibliometric analysis extends to contextual, evolutionary, and spatial dimensions, allowing for a comprehensive understanding of the identified clusters. The ensuing clusters serve as a roadmap, categorizing publications based on their contextual relevance, evolutionary trajectory, and spatial focus, which enhances the identification of key works in the field, facilitating a nuanced understanding of the current state of external public debt management research. The synthesis of findings from the content-contextual block emphasizes a primary orientation toward understanding the dynamic interplay between external public debt management and economic development. Furthermore, the contextual-temporal block identifies four distinct stages in the evolution of research focus, highlighting the shifting emphasis over time. A discernible pattern of heightened research activity in external public debt management across various countries in recent decades is revealed through spatiotemporal analysis. The interdisciplinary nature of this field is underscored by the dominance of economics, econometrics, finance, business, management, and accounting in dedicated research.