Application Of Glue Research Articles

Evaluation of the Impact of Bricks of Various Characteristics on Internally Insulated Masonry Walls in Cold Climate

Energy consumption in historic building stock is high compared to current energy efficiency standards. The heritage value of the façade and the limited space on the external surface in densely populated urban streets limit the application of external insulation. Internal insulation can be applied instead. However, it is considered to be a riskier technology due to moisture-related damage. In addition to mold growth and wood rot, frost damage should be considered in cold climates. This study aims to assess the impact of a vapor-open capillary-active calcium silicate internal insulation system with and without adhesive glue on the hygrothermal behavior of masonry from various historic bricks in cold climates by performing numerical simulations in the software Delphin. Test results of hygrothermal properties of 40 historic brick samples were used in numerical experiments to assess the impact of a brick type, the quality of the application of calcium silicate (with or without adhesive), and the impact of cold climate on the hygrothermal behavior. Results show that temperature behavior is similar to all wall types whereas a large difference is observed in moisture behavior. The application of adhesive glue tends to reduce moisture spikes caused by rain events when compared to the same samples without adhesive. Findings only partly correspond to other studies on factors affecting moisture behavior.

Technology of Automated Application of Glue on Film Scale

Technology of Automated Application of Glue on Film Scale

Revolutionizing Fistula Treatment: A Case Series on the Application of Kshara Sutra Therapy

A chronic, abnormal contact between the epithelialized anal canal surface and the perianal skin is known as an anal fistula (fistula-in-ano), which can cause serious morbidity and lower quality of life. Traditional surgical procedures as well as more contemporary ones, like the application of fibrin glue, a plug, or closure of the intersphincteric fistula tract, are available as treatment options (LIFT). These conventional techniques, however, may have varying degrees of efficacy, and some may be connected to the risk of incontinence. The Kshara Sutra, an antiquated Ayurvedic parasurgical procedure, was used to treat a case series of 10 patients with a range of anal fistulas, ranging in complexity from simple to complex presentations. Patients in the cases range in age from 22 to 55, both male and female. Despite variations in their particular circumstances, all patients had completely healed fistulas following Kshara Sutra treatment. Additionally, this treatment showed promise in simplifying complicated fistulas. These results add to the expanding body of research that supports the use of Kshara Sutra therapy for the repair of anal fistulas, offering a promising, secure, and maybe more effective option than traditional surgical procedures.

Endoscopic closure of recurrent tracheoesophageal fistula using argon plasma coagulation: A case report

Recurrent tracheoesophageal fistula (RTEF) after surgical repair of esophageal atresia remains a serious complication. Open surgical repair for RTEF is associated with high levels of postoperative morbidity, mortality and repeat recurrence. Although endoscopic management has been expected to be an alternative to re-surgery, the optimal endoscopic management of RTEF remains to be determined. This report describes a successful experience of argon plasma coagulation (APC) for the closure of an intractable RTEF. A newborn male diagnosed as having esophageal atresia with tracheoesophageal fistula (TEF) underwent a primary surgical repair. At 17 months of age, an oral contrast study showed the recurrence of the TEF, and subsequently he underwent a second open surgery. However, a postoperative esophagogram revealed a second recurrence of the TEF. Then, endoscopic treatment options were considered and APC was employed to coagulate the fistula epithelium. At 31 months of age, APC followed by fibrin glue application was performed. By this procedure the RTEF could be occluded safely and successfully without any complications. APC is a simple, safe and effective procedure, and is therefore worth trying as a first attempt for the treatment of RTEF.

Case Report: Central Corneal Perforation Management Secondary to Neurotropic Keratopathy in the Absence of Tectonic Corneal Graft, Barcelona CP

Purpose To present the emergency management of a patient with corneal perforation secondary to post-herpetic neurotrophic keratopathy (NK) with fibrin glue and amniotic membrane transplantation (AMT) in the absence of a tectonic corneal graft. Report of Case A 26-year-old male patient with a history of herpetic keratitis was admitted to our clinic with a finding of approximately 1 mm corneal central perforation in his right eye. The best corrected visual acuities of right and left eyes were 2.3 and 0 logMAR, respectively. Anterior segment examination revealed corneal edema, vascularization, shallow anterior chamber and central corneal perforation in the melting area. No pathology of the retina or vitreous was detected in B-scan ultrasonography. Anterior and posterior segment examination of left eye was normal. Conventional approaches including bandage contact lens failed to buffer the leak. Since human corneal donor tissue was not available, fibrin glue application from inside to outside along the perforation area combined with AMT was applied. Even after 2 weeks when the amnion was degraded, it was observed that the perforation area was stable without any additional intervention. Conclusion NK is one of the challenging reasons of corneal perforation. Although tectonic keratoplasty is the main treatment modality owing to transparency and high tissue resistance in the central corneal perforation repair, alternative treatment methods are necessary due to difficulty of access to donor cornea. Tissue adhesives and AMT are conservative methods to buffer leak with easier access. Present case clarifies the importance of alternative management modalities of corneal perforation in the absence of tectonic graft. Considering that only 1 donor cornea is available to 70 needed around the world, corneal perforation repair with fibrin glue combined with AMT seems wise.

Frey syndrome after conservative parotidectomy: Importance of closing the remnant parotid parenchyma

Frey syndrome (FS) is a typical late complication following parotidectomy. Parotid surgery without proper coverage or reconstruction of exposed parotid parenchyma may contribute to the development of FS. Therefore, this study compared the closure versus the non-closure of exposed parotid parenchyma in the occurrence of FS. This study included 195 patients with parotid lesions who underwent partial or superficial parotidectomy plus closure or non-closure of exposed parotid parenchyma, both with the application of fibrin glue. Two surgical methods of closure and non-closure were allocated to patients without randomization and blinding processes. The primary outcome was FS, and the second outcome was other complication rates. The closure and non-closure of exposed parotid parenchyma were performed in 102 and 93 patients, respectively. Early postoperative complications occurred with temporary events: transient facial weakness, 32 (16.4%); hematoma, 13 (6.7%); and wound infection, 2 (1.0%), without statistical difference between the two groups (P>0.1). However, sialocele occurred in the non-closure group (n=19) more than in the closure group (n=7) (P=0.005). In the first postoperative year, decreased sensation and local pain were found in 16 patients (8.2%) and 9 patients (4.6%), respectively, with no statistical difference between the two groups (P>0.1). FS was found more in the non-closure group (n=19, 20.4%) than in the closure group (n=4, 3.9%) (P<0.001). The closure of exposed parotid parenchyma and covering fascia is preferred over the non-closure to prevent FS.

Влияние древесиноведческих и технологических факторов на прочность зубчатого соединения в клееных конструкциях

The paper presents the results of finger joint quality assessment at the static bending in the production of wooden laminated structures. We selected the softwood samples randomly. This study concerns with detecting of bending stress with load application in thirds of the plate span. This loading scheme allows us to make pure bending deformation for the area under study. 53.3% of the selected samples had the values of maximum bending stress satisfying the regulatory requirements. The average value of the destructive bending stress in the finger joint was 19.8 MPa, the coefficient of variation - 8.9%. According to the study results, surface defects and the glue application uniformity on surface of the joint significantly affected the strength of finger joints. This explains the insufficient adhesive strength in the place of finger joint and, as a consequence, low strength at static bending. Therefore, it is necessary to replace glue-bearing applicators, and control the technological process of wooden laminated structures manufacturing regularly.

Clinical Features, Risk Factors, and Management of Candida Keratitis

ABSTRACT Background/Aims To determine the clinical features, predisposing factors, and management of infectious keratitis caused by Candida spp. Methods Retrospective chart review. Results The medical records of 52 patients (54 eyes) with Candida keratitis were available for statistical analysis. Thinning of the corneal stroma was identified in 34 eyes (63.0%), and corneal perforation occurred in 16 eyes (29.6%). Corneal thinning and perforation were more common in Candida albicans compared with non-albicans (P-val < .001, P = .09, respectively). The most common predisposing factors for Candida keratitis were topical steroid use (21 patients, 40.4%), previous corneal transplantation (17 patients, 32.7%), and preexisting ocular surface disease (15 patients, 28.8%). Fourteen eyes (25.9%) required cyanoacrylate glue application and 10 eyes (18.5%) underwent therapeutic penetrating keratoplasty (TPK). Conclusion Local immunosuppression and ocular surface disease play an important role in Candida keratitis. C. albicans appears to be more invasive compared with non-albicans spp.

Effect of Glue Spread on Bonding Strength, Delamination, and Wood Failure of Jabon Wood-Based Cross-Laminated Timber Using Cold-Setting Melamine-Based Adhesive.

Cross-laminated timber (CLT) has become a popular engineered wood product due to its innovative properties and rapid development, which involves the use of various wood species and adhesives. This study aimed to assess the effect of glue application on the bonding strength, delamination, and wood failure of CLT made from jabon wood and bonded with a cold-setting melamine-based adhesive at three different rates: 250, 280, and 300 g/m2. The adhesive was composed of melamine-formaldehyde (MF) by adding 5% citric acid, 3% polymeric 4,4-methylene diphenyl diisocyanate (pMDI), and 10% wheat flour. Adding these ingredients increased the adhesive viscosity and decreased the gelation time. The CLT samples, made using cold pressing in the melamine-based adhesive at a pressure of 1.0 MPa for 2 h, were evaluated as per the standard EN 16531:2021. The results revealed that a higher glue spread resulted in a greater bonding strength, lower delamination, and a higher wood failure. The glue spread was shown to have a more significant influence on wood failure compared with delamination and the bonding strength. The application of 300 g/m2 glue spread (MF-1) on the jabon CLT led to a product that met the standard requirements. The use of modified MF in cold-setting adhesive produced a potential product that could be a feasible option for future CLT production in terms of its lower heat energy consumption.

Does perivascular fibrin glue application have a preventive effect for the endothelial damage on saphenous vein graft? An experimental model.

The effect of tissue adhesives on coronary grafts in cardiac surgery is a controversial issue. The aim of this study is to investigate the effect of fibrin glue (FG) applied around the saphenous vein grafts (SVG) in preventing cellular damage resulting from intraluminal pressure increase. Twenty volunteer patients were included in this ex vivo study. The SVGs remained after coronary artery bypass grafting were connected to the arterial line of the cardiopulmonary bypass circuit. The grafts were divided into two segments and one segment received perivascular FG applied whereas the other part was used plain. SVGs were kept in circulation at 120 mmHg pressure 250 mL/min flow rate for 60 min. The tissues were sent for histopathological examination to determine the endothelial damage. Endothelial damage was more pronounced in the control group when compared with the FG group. In the FG group, no damage was seen in 13 samples and no Type 3 endothelial damage was observe whereas Type 1 injury was detected in seven specimens, Type 2 injury was observed in seven specimens, and Type 3 injury was detected in two specimens in the control group. Perivascular application of FG on the SVG showed a protective effect against endothelial damage resulting from increased intraluminal pressure.

The use of commercial fibrin glue in dermal replacement material reduces angiogenic and lymphangiogenic gene and protein expression in vitro.

Commercial fibrin glue is increasingly finding its way into clinical practice in surgeries to seal anastomosis, and initiate hemostasis or tissue repair. Human biological glue is also being discussed as a possible cell carrier. To date, there are only a few studies addressing the effects of fibrin glue on the cell-molecular level. This study examines the effects of fibrin glue on angiogenesis and lymphangiogenesis, as well as adipose-derived stem cells (ASCs) with a focus on gene and protein expression in scaffolds regularly used for tissue engineering approaches. Collagen-based dermal regeneration matrices (DRM) were seeded with human umbilical vein endothelial cells (HUVEC), human dermal lymphatic endothelial cells (LECs), or adipose-derived stem cells (ASC) and fixed with or without fibrin glue according to the experimental group. Cultures were maintained for 1 and 7days. Finally, angiogenic and lymphangiogenic gene and protein expression were measured with special regard to subtypes of vascular endothelial growth factor (VEGF) and corresponding receptors using Multiplex-qPCR and ELISA assays. In addition, the hypoxia-induced factor 1-alpha (HIF1a) mediated intracellular signaling pathways were included in assessments to analyze a hypoxic encapsulating effect of fibrin polymers. All cell types reacted to fibrin glue application with an alteration of gene and protein expression. In particular, vascular endothelial growth factor A (VEGFA), vascular endothelial growth factor B (VEGFB), vascular endothelial growth factor C (VEGFC), vascular endothelial growth receptor 1 (VEGFR1/FLT1), vascular endothelial growth receptor 2 (VEGFR2/KDR), vascular endothelial growth receptor 3 (VEGFR3/FLT4) and Prospero Homeobox 1 (PROX1) were depressed significantly depending on fibrin glue. Especially short-term fibrin effect led to a continuous downregulation of respective gene and protein expression in HUVECs, LECs, and ASCs. Our findings demonstrate the impact of fibrin glue application in dermal regeneration with special regard to angiogenesis and lymphangiogenesis. In particular, a short fibrin treatment of 24hours led to a decrease in gene and protein levels of LECS, HUVECs, and ASCs. In contrast, the long-term application showed less effect on gene and protein expressions. Therefore, this work demonstrated the negative effects of fibrin-treated cells in tissue engineering approaches and could affect wound healing during dermal regeneration.

A rare case of corneal perforation with glass perchlet fish

Penetrating ocular injuries following direct impact of fish are rare. A 26-year-old man presented to the emergency department with history of pain and blurring of vision following injury to the left eye due to the impact of glass perchlet fish. Ocular examination revealed best corrected visual acuity of log of minimum angle of resolution (logMAR) 0.18, eyelid edema, blepharospasm, and circumcorneal congestion. A full-thickness corneal laceration measuring 3 mm, confirmed by positive Seidel's test, and a partial-thickness corneal laceration measuring 1.5 mm were noted. Patient was managed by application of cyanoacrylate glue and bandage contact lens. We report the first case of corneal perforation by glass perchlet fish.

Effects of platelet-rich plasma glue placement at the prostatectomy site on erectile function restoration and cavernous nerve preservation in a nerve-sparing prostatectomy rat model

BackgroundDespite the widespread use of nerve-sparing prostatectomy techniques, the incidence of post-operative erectile dysfunction (ED) remains high. Early intracavernous (IC) injection of platelet-rich plasma (PRP) after nerve crushing improves erectile function (EF) in rats by promoting cavernous nerve (CN) regeneration and preventing structural changes in the corpus cavernosum. However, the neuroprotective effects of the in situ application of PRP glue in rats after CN-sparing prostatectomy (CNSP) remain unclear. AimThis study aimed to investigate the effects of PRP glue treatment on EF and CN preservation in rats after CNSP. MethodsAfter prostatectomy, male Sprague–Dawley rats were treated with PRP glue, IC PRP injection, or their combination. The intracavernous pressure (ICP), mean arterial pressure (MAP), and CN preservation status in the rats were evaluated after 4 weeks. Results were corroborated using histology, immunofluorescence, and transmission electron microscopy. ResultsThe PRP glue-treated rats showed 100% CN preservation and significantly higher ICP responses (the ratio of maximum ICP to MAP (0.79 ± 0.09)) than the CNSP rats (the ratio of maximum ICP to MAP (0.33 ± 0.04)). PRP glue also significantly increased neurofilament-1 expression, indicating its positive effect on the CNs. Furthermore, this treatment significantly increased the expression of α-smooth muscle actin. Electron micrographs revealed that PRP glue preserved the myelinated axons and prevented atrophy of the corporal smooth muscle by maintaining the adherens junctions. ConclusionsThese results indicate that PRP glue is a potential solution for EF preservation by neuroprotection in patients with prostate cancer who are likely to undergo nerve-sparing radical prostatectomy.

Endoscopic application of fibrin glue may be a feasible method of treatment for postintubation tracheal lacerations in cats.

To determine the feasibility of endoscopic application of fibrin glue for the treatment of experimentally induced postintubation tracheal laceration (PITL) in feline cadavers. The secondary objective was to determine the optimal technique for application of the fibrin glue. 20 feline cadavers (n = 10 fresh and 10 frozen). An experimentally induced tracheal rupture was created via overinflation of an endotracheal tube cuff. After endoscopic identification of the tracheal tear, fibrin glue was instilled into the tracheal defect in either a bridging or filling fashion. Following the procedure, the airway of each cat was examined and leak tested. Length of tear, volume of glue applied, procedural time, and glue efficacy were recorded. Experimentally induced tracheal lacerations were full thickness with a mean length of 3.27 ± 0.96 cm. A complete seal was attained in 6 of the 9 fresh cadavers when filling the defect with fibrin glue. In the remaining 3 fresh cadavers, air leakage was restricted to the dorsal mediastinum. Bridging the defect with fibrin glue did not attain a seal in fresh or frozen cadavers. The median volume of glue used to fill defects in fresh cadavers was 0.5 mL (range, 0.4 to 2 mL). Procedural time for the application of fibrin glue was 10.5 ± 4.1 minutes for bridging the defect and 7.8 ± 1.5 minutes for filling the defect. Endoscopic application of fibrin glue may be a feasible method of treatment for PITL in cats.

Evaluation of Incisional Wound Healing in Dogs after Closure with Staples or Tissue Glue and Comparison to Intradermal Suture Pattern.

The study aimed to monitor the healing process in the canine skin following surgical incision and closure using staples or tissue glue and to compare them with the intradermal suture pattern. Surgically created skin incisions in 10 dogs were apposed with staples, tissue glue (n-butyl cyanoacrylate) and continuous intradermal pattern. The cosmetic appearance of the wounds was blindly evaluated on days 7, 14 and 28 and once a month until the end of the experiment, i.e., one year after the incision. Ultrasonographic and clinical evaluation was performed on days 0-10, 12, 14, 16, 18, 21, 24 and 28, once a week until the end of the 3rd month and once a month until the end of the experiment. Histopathological evaluation was performed on days 7, 14, 28, 180 and 365. The median time required for the performance of each technique differed significantly between techniques; stapling lasted 21 s, glue 2 min 16 s and intradermal 15 min 37 s. Cosmetic appearance with glue was statistically worse than staples and intradermal. The clinical appearance of intradermal was significantly better than glue and staples. No significant differences were found at histological evaluation; however, glue had the worst score throughout the experiment. The overall evaluation of the techniques showed that glue had the worst score compared to intradermal and staples, with the difference being statistically significant in the first postoperative week. Intradermal suture pattern is much better than glue application for skin closure in dogs, whilst is not significantly better than staples. Staples should be preferred when time is an important factor.

Sling technique in microvascular decompression surgery for trigeminal neuralgia: early experience and functional outcomes

BackgroundTrigeminal neuralgia (TGN) is a facial pain disorder often caused by arterial compression of the trigeminal nerve. Microvascular decompression (MVD) remains the most definitive treatment for this disorder, with a reported cure rate between 60 and 80%. MVD techniques often involve a retrosigmoid craniotomy with placement of an inert foreign material, such as Gore-Tex or Teflon, between the nerve and the compressing vessel.Recurrence of TGN after MVD has been associated with vessel migration and adhesion formation. In this study, we tested the use of Gore-Tex sling, fixed in place with fibrin glue to displace the compressing vessel away from the nerve.ResultsThis is a retrospective study including 20 patients who had an MVD for treatment of idiopathic TGN where a sling of Gore-Tex was used with the application of fibrin glue to prevent dislocation of the vessel. It showed that sling MVD technique is an effective method for treatment of classic trigeminal neuralgia. Eighteen patients improved within 2 weeks postoperatively. One patient had recurrence of symptoms and was reoperated 1 year later.ConclusionGore-Tex slinging technique is a safe simple technique for preventing re-dislocation of the offending vessel and thus recurrence of symptoms. However, larger series is needed to judge on the long-term efficacy and safety of this technique.

Tissue Adhesives for the Management of Corneal Perforations and Challenging Corneal Conditions.

Corneal perforations are ophthalmological emergencies which can have serious and detrimental consequences, if not managed timely and appropriately. These are a significant cause of ocular morbidity and can result in decreased vision, blindness, and even loss of the eye. Corneal perforations can be managed using a range of treatment approaches, including temporary solutions such as the application of corneal glue and bandage contact lens, as well as definitive treatment such as corneal transplantation. Tissue glues/adhesives were developed as substitutes for sutures in ophthalmic surgery. Unlike sutures, these glues are associated with shorter overall surgical times and reduced inflammation, thus improving postoperative comfort without compromising wound strength. The available tissue adhesives can be broadly classified into two types: synthetic (eg, cyanoacrylate derivatives) and biological (eg, fibrin glue). Cyanoacrylate glue is chiefly used as a corneal patch to manage acute corneal perforations and improve visual outcomes. Fibrin glue can be used instead of cyanoacrylate glue in many conditions with the benefits of reduced conjunctival and corneal inflammation and reaction. Apart from this, each type of adhesive is distinct in terms of its benefits as well as limitations and is accordingly used for different indications. The present review focuses on the two main types of tissue adhesives, their applications in the management of corneal perforations, the associated complications, safety and efficacy data related to their use available in the literature and the need for newer adhesives in this field.

Management of simultaneous bilateral immune-mediated peripheral ulcerative keratitis.

Peripheral ulcerative keratitis (PUK) is a sight threatening disease, often immune mediated and can rapidly progress to corneal perforation. Here we report the successful management of simultaneous bilateral peripheral ulcerative keratitis presenting with corneal perforation with surgical intervention and systemic immunosuppression. A 41-year-old female presented with similarly located super-nasal peripheral ulcerative keratitis (PUK) in both eyes and focal area of adjoining scleritis in the left eye. Serological investigations for systemic immune-mediated conditions showed positive rheumatoid factor test. She underwent cyanoacrylate glue application in both eyes, and was started on topical and oral corticosteroids and oral immunomodulators, and the right eye stabilized. The left eye required a second surgical intervention with a corneal patch graft following which the condition stabilized. This case highlights the importance of investigating for an underlying systemic etiology in PUK and the role of systemic immunosuppression prior to and after surgical intervention in order to arrest the disease and prevent recurrences.

Fibrin Glue Sealant: An Effective Modality to Mitigate Postoperative Seroma After Modified Radical Mastectomy.

Introduction Modified radical mastectomy is a common modality used in treating breast cancer and often presents a series of post-operative challenges. Seroma formation is the most common complication with no single method shown to be reliably effective against it. Fibrin glue is one such modality. There is a paucity of studies describing the utility of fibrin glue to prevent seroma formation. Aim To evaluate the effect of intraoperative application of fibrin glue sealant on drain output and seroma formation in patients undergoing modified radical mastectomy by comparing outcomes between the two groups. Method This is a prospective observational study. Fibrin glue application was done intra-operatively prior to closure in one group. Standard closure procedures with drain placement were undertaken in another group and their outcomes were analyzed for both groups. Results Drain output on postoperative day 1 (POD 1) as well as total drain output were recorded for both groups and the difference in mean was found to be significant (p<<0.05 and 0.049, respectively. Distribution of patients according to the volume of seroma formation was done; this difference of means was also found to be significant (p=0.004). Further, the difference of mean for the number of days the drain was in-situ was found to be significant. Conclusion Fibrin sealant used during modified radical mastectomy closures decreased the rates and volumes of seroma formation. This led to quicker drain removals and less patient discomfort.

Coupling analysis between cost and carbon emission of bamboo building materials: A perspective of supply chain

Bamboo building materials with carbon storage potential are considered to be the key to low carbon emissions and sustainable development in the construction industry. However, the willingness to pay and the carbon storage effect of bamboo materials still face major obstacles, and the supply chain needs to be optimised as it affects the economic and green benefits of bamboo building materials. This study aims to investigate the carbon emission and cost distribution of bamboo building materials, analyse the key influencing factors and propose an equilibrium optimisation strategy. Results indicate that ‘Carbonisation’, ‘Glue application’ and ‘anti-mould, anti-corrosion and drying’ in the production phase are the major contributors to carbon emissions, which are mainly generated by biomass fuel carbonisation kiln, adhesives and anti-mould preservatives. ‘Transportation from front-end factory to back-end factory” and ‘Transportation from back-end factory to construction site” in the supply phase are the largest obstacles to cost, and transportation distance is the key factor. The results were accepted by the manufacturer and facilitated the screening of the best equilibrium control strategy: clean energy replacement, use of new adhesives and anti-mould products and adjustment of transport distances. After the implementation of the optimisation strategy, carbon emissions were reduced by 40.10% and costs were reduced by 35.31%, indicating that the effect of the optimisation strategy is obvious. This study explores the carbon reduction potential of bamboo building materials, provides actionable guidance for producers of building materials and architects, and promotes the willingness of society to accept payment.