Abstract Background: Maintenance endocrine therapy (mET) is increasingly used as part of the post-chemotherapy treatment for HER2-positive, hormone receptor-positive metastatic breast cancer (HER2+, HR+ mBC). However, the impact of mET on delaying brain metastases (BM) and other clinical outcomes is unclear. As the time from taxane completion to mET initiation can vary considerably, standard cohort methods with fixed index dates can lead to immortal time and selection bias. This study estimates the effect of different mET treatment strategies (TS) on BM-free survival (BMFS), overall survival (OS), and real-world progression-free survival (rwPFS) in patients (pts) with HER2+, HR+ mBC without BM. Methods: The study used the Flatiron Health database (January 2011-September 2024). mET included aromatase inhibitors, selective estrogen receptor degraders or modulators, and ovarian function suppression. Our target trial compared four TS in pts with HER2+, HR+ mBC who had completed ≥5 cycles of 1L HER2-targeted therapy + taxane (baseline was last taxane administration): Arm 1: mET initiation within 3 months (mo) of baseline; Arm 2: no mET initiation within 3 mo of baseline (initiation was possible afterwards); Arm 3: no mET initiation within 60 mo of baseline; and Arm 4: mET initiation between 4-6 mo of baseline. In all TS, CDK4/6 inhibitor use was not permitted and pts who initiated 2L treatment/had a BMFS/OS/rwPFS event were excluded from the TS. In the target trial emulation (TTE), pts were assigned to all TS with which their baseline data were compatible, creating four clones (TS were not distinguishable at baseline), and were censored upon deviation from the assigned TS. BMFS, OS, rwPFS were measured up to 60 mo from last taxane administration (LTA); risk differences and risk ratios were estimated via pooled logistic regression adjusted for baseline confounders (de novo vs. recurrent disease, disease-free interval, treatment at an academic center, Roche Prognostic Score, last HR test being negative despite prior positive tests). Estimates were bounded with percentile-based 95% confidence intervals (CI) estimated via bootstrapping. Sensitivity analyses included changes in grace period, time discretization, functional form of time, censoring of early death events, and simulation of uniform initiation of TS. Results: The TTE (N = 784) evaluated 391 pts who received ET within 3 mo and 393 pts who did not receive ET within 3 mo. At the time of taxane completion, baseline characteristics were generally balanced between pt groups, except ET pts were more likely to be treated in an academic center (25.8% vs. 17.3%) and less likely to have a negative latest HR test (3.6% vs. 12.7%). The difference in the risk of death (95% CI) comparing Arm 1 vs. Arm 3 was -3.2% (-5.6, -0.8) at 12 mo and -6.5% (-10.9, -1.7) at 24 mo (negative estimates favor Arm 1). The corresponding risk differences for rwPFS were -6.8% (-16.0, 0.9) and -10.1% (-20.3, -1.9), and for BMFS, -2.0% (-8.9, 4.7) and -4.7% (-13.0, 2.8). Treatment effect estimates were less precise beyond 36 mo due to loss to follow-up. Similar estimates were found against other TS, although the limited number of pts with data compatible with Arm 4 yielded imprecise estimates. Conclusions: Early mET within 3 mo of LTA was associated with improved clinical outcomes in pts with HER2+, HR+ mBC (although the limited number of BMFS events and modest estimates prevent making any firm conclusions). The TTE framework for comparative effectiveness studies with flexible treatment initiation helps align real-world data with randomized clinical trials, supporting better design of real-world data studies including comparisons of TS that can inform clinical practice. Citation Format: T. Sanglier, I. Gravestock, J. Leone, M. Secrest, C. Tchakoute, E. Restuccia, F. Montemurro, M. Shivhare, A. Knott, P. Lambert, D. Martinez, P. Luhn, X. Garcia de Albeniz Martinez, S. Tolaney, N. Lin, S. Sammons. Estimating the effect of initiating early maintenance endocrine therapy on brain metastases-free survival and other clinical outcomes in patients with HER2+/HR+ mBC without brain metastases: A target trial emulation [abstract]. In: Proceedings of the San Antonio Breast Cancer Symposium 2025; 2025 Dec 9-12; San Antonio, TX. Philadelphia (PA): AACR; Clin Cancer Res 2026;32(4 Suppl):Abstract nr PS5-01-10.

Abstract Background Clinical trials have demonstrated that subcutaneous infliximab (IFX-SC) is not inferior to intravenous infliximab (IFX-IV). However, due to its superior pharmacokinetic properties, IFX-SC is now considered a “biobetter”. This study aims to assess whether these improved pharmacokinetic features translate into differences in persistence and efficacy in real-world practice. Methods A prospective observational study was conducted including patients with active inflammatory bowel disease initiating IFX-IV or IFX-SC based on medical criteria, cost considerations, or patient preference. The objectives were to compare persistence rates, concomitant medication use, clinical response, and biomarker outcomes between the two groups. Results To date, 205 patients have been recruited from 19 different centers. Of these, 83 (52 IFX-IV, 31 IFX-SC) completed the follow-up visit at months 4–7. Use of immunosuppressants was significantly higher in the IFX-IV group (IFX-SC 9.6% vs. IFX-IV 38.4%, p = 0.005). Corticosteroid use was also higher in the IFX-IV group but did not reach statistical significance (IFX-SC 3.2% vs. IFX-IV 9.6%, p = 0.4). One patient per group switched administration route, while dose intensification was more frequent in the IFX-IV group (IFX-SC 3.2% vs. IFX-IV 40.4%, p = 0.001). A total of 9 patients discontinued treatment (IFX-SC 13% vs. IFX-IV 9.6%, p = 0.72), most due to pharmacodynamic failure (55.5%). The mean drug level was 16.7 µg/mL for IFX-SC and 11.3 µg/mL for IFX-IV. No significant differences in clinical or biomarker-based efficacy were observed between groups (Table 1). IFX-SC was the preferred route among patients, whereas economic reasons were the main determinant for selecting IFX-IV (Figure 1). Conclusion In this multicenter real-world cohort, subcutaneous infliximab demonstrated pharmacokinetic advantages and similar rates of treatment persistence and efficacy compared to the intravenous formulation, with a lower need for concomitant immunosuppression and dose intensification. Patients showed a statistically significant preference for the IFX-SC route of administration. Conflict of interest: Dr. González Partida, Irene: I have received funding for training and/or promotional talks from Amgen, Abbvie, Biogen, Falk, Kern Pharma, Johnson&Johnson, Lilly, Pfizer, Takeda and Tillots. De Lucas, Rocio: No conflict of interest Calvo, María: I have received funding for training and/or promotional talks from Amgen, Abbvie, Biogen, Falk, Kern Pharma, Johnson&Johnson, Lilly, Pfizer, Takeda and Tillots. Miranda-Bautista, Jose: No conflicts Olmos Jerez, Jose: I declare that I have no conflict of interest in this study. Rueda Garcia, Jose Luis: José Luis Rueda García has received financial support for traveling and educational activities from Kern Pharma, Abbvie, Johnson&Johnson, Pfizer, Eli Lilly, Takeda, Ferring, Tillotts Pharma, Faes Farma, Norgine and Casen and he has received fees as a speaker from Abbvie, Johnson&Johnson, Pfizer, Eli Lilly and Takeda. Garcia De La Filia Molina, Irene: I have no conflicts of interest Martin, Daniel: I have served as speaker for and received consulting fees from Abbvie, Takeda, Jansen, Ferring, Tillots, Dr. Falk Pharma, Faes Pharma an Persan Hernandez Camba, Alejandro: No conflict of interest Sola Sánchez, Javier: Has served as speaker for Takeda, Abbvie, Amgen and Sanofi García-Castellanos, Raquel: none Olmedo Moreno, Cristina: I declare to have received support for educational meetings from Abbvie, Takeda, Sandoz, Janssen and Alfasigma. Matallana Royo, Virginia: I have received fees as a speaker and consultant from Abbvie, Allergan, Casen Recordati, Italfármaco S.A., Janssen Cilag S.A., Merck Sharp & Dohme Española S.A., Pfizer, Schwabe Farma Ibérica S.A.U., and Takeda Calvo Moya, Marta Isabel: No conflict of interest Botella Mateu, Belén: No conflicts

Abstract Digital technologies including wearable censors and smartphones facilitate the real-time assessment of psychological and physiologic states, behavioral patterns, and cognitive functioning, as well as person-level environmental exposures in the course of daily life. Further, these methods allow for continuing follow-up of older adults when in-person assessments are not possible, such as during infectious disease outbreaks, or when older adults are not able to travel to a study clinic. This session will illustrate the application of digital technology to the study of cognitive aging within the Einstein Aging Study (EAS) cohort of community residing adults. The EAS utilizes an integrative approach that combines ecologically valid ambulatory measures of both exposures and cognition with traditional clinic-based assessments in a diverse community-based sample of adults aged 60 and above. The session will illustrate the feasibility and utility of this approach for: 1) maintaining ongoing follow-up in older adults and obtaining real-time longitudinal data during environmental events (Dr. Roque), 2) using GPS data to derive person-specific indices of neighborhood environment exposures as individuals navigate everyday life (Dr. Hyun), 3) understanding how glucose regulation impacts cognition in older adults with diabetes (Dr. Hoogendoorn), 4) examining real time associations between subjective cognitive concerns and cognitive performance (Dr. Garcia De La Garza), and 5) prospectively tracking psychological health during the COVID-19 pandemic (Dr. Wang).

ABSTRACT Garcia de Orta (1501–1568) is largely remembered in academic circles as a minor figure in the history of medicine. The son of converts from Judaism to Catholicism, he fled escalating persecution in Portugal and settled in Goa, where he practised medicine and wrote Colóquios dos simples e drogas da Índia, a dialogue that is generally viewed as nothing more than an unorthodox manual of tropical materia medica. However, here, I cast light on an important philosophical contribution that de Orta makes through this dialogue. I argue that he points to several epistemological failings made by most European natural philosophers in Europe. For de Orta, I argue, the tendency towards four forms of Eurocentrism is a significant cause of these errors. However, de Orta is prone to two of the very sorts of Eurocentrism to which he objects. He is therefore guilty of some of the same failings. Consequently, he makes for a complex opponent of Eurocentrism in the history of philosophy: whilst he provides a nuanced philosophical critique of Eurocentrism, he shows signs of struggling to entirely escape Eurocentrism himself.

ABSTRACT This article investigates how certain kinds of reading and meditation reduce attention to the here-and-now in order to leave room for imaginative experiences in carefully crafted religious and cultural designer environments. The article thereby engages with recent accounts on cultural acquisition and religious beliefs. From the perspective of active inference and 4E cognition, we argue that designer environments allow practitioners to go beyond modulating their predictions according to the minds of others, and instead enable them to go “elsewhere,” that is, to imaginatively experience different sets of probabilities that can change how they predict the world in the here-and-now. Three different works are studied: Amadis of Gaul (1508), a best-selling series of chivalric novels by Garcia de Montalvo, The Spiritual Exercises (1548), a meditation manual by Ignatius of Loyola, as well as Don Quixote (1605 and 1615) by Miguel de Cervantes. These works have in common that they rebuild expectations in relation to the self by positioning it in new environments, and thereby extending the range of experience. Through such thinking “elsewhere” in designer environments, we argue, readers and meditators can modulate their attentional systems so as to perceive and act in the world in new ways.

To characterize a Portuguese population of patients with juvenile idiopathic arthritis (JIA) and to evaluate possible associations between clinical factors and ocular involvement. Patients diagnosed with JIA in the previous 20y in Hospital Garcia de Orta were included. Data were assessed from Reuma.pt database. Associations between demographic (age and sex), clinical (articular involvement, extra-articular manifestations, biological therapy), laboratory data [anti-nuclear antibodies, anti-cyclic citrullinated peptide (CCP) antibodies, rheumatoid factor, human leukocyte antigen B27 (HLA-B27), C-reactive protein, erythrocyte sedimentation rate] and ocular involvement were assessed. Statistical analysis was performed using Chi-square for categorical variables and Mann-Whitney test for continuous variables. Totally 91 patients were included, 11 (12%) with previous episodes of uveitis. There was a statistically significant preponderance of early age at JIA diagnosis (mean 4.73 vs 9.58y, P=0.008), antinuclear antibodies positivity (P=0.01), and oligoarticular subtype (P=0.04) in the Juvenile idiopathic arthritis-associated uveitis (JIA-U) group. Ocular complications occurred in 36.4% of patients (n=4): cataracts (n=2), band keratopathy (n=1) and posterior synechiae (n=1). The occurrence of complications was corelated with a shorter period between JIA diagnosis and the first JIA-U episode (mean 0.67 vs 4.88y, P=0.012) but not with age at JIA diagnosis or articular involvement. There was erythrocyte sedimentation rate elevation in the 12mo preceding uveitis (mean 40.5 mm/h, range 13-83). The occurrence of JIA-U shortly after JIA diagnosis is shown to be a potential risk factor for ocular complications.

Traces of Ayurveda in Garcia de Orta's Treatise (Portuguese India of 16th Century): An Essay

Tuberculosis (TB) treatment is highly effective, but response to therapy can vary by geography, race, and ethnicity. We assessed for differences in TB treatment response in a representative and heterogeneous Brazilian population. We estimated genetic ancestry proportion according to major ancestry groups (African, European, and Amerindian ancestry) in the Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil cohort. RePORT-Brazil is an observational prospective cohort study of individuals with newly-diagnosed, culture-confirmed, pulmonary TB. TB treatment outcomes that were attributed to TB treatment included Grade 2 or higher adverse drug reaction (ADR), Grade 3 or higher ADR, hepatic ADR, and failure/recurrence. Ancestry proportion was the main predictor in logistic regression for each outcome, with adjustments for candidate confounders. There were 941 pulmonary TB patients included in this study. We observed a decreased risk of Grade 2+ ADR when African ancestry proportion increased by 10% (Odds Ratio [OR] 0.41, 95% Confidence Interval [CI] 0.20 -0.85) and an increased risk for Grade 2+ ADR with increasing European ancestry (OR 2.84, 95% CI 1.47 - 5.48). We then performed the same analysis adding HIV status as an interaction term. The decreased risk for Grade 2+ ADR seen for African ancestry proportion did not hold for persons living with HIV; we observed increased risk for Grade 2+ ADR with increasing African ancestry proportion. There were no associations with Amerindian ancestry or for other treatment outcomes. In this Brazilian TB cohort, toxicity risk was associated with African and European ancestry, divergent, and affected by HIV. #RePORT-Brazil Consortium members include: Aline Benjamin and Flavia M. Sant'Anna Instituto Nacional de Infectologia Evandro Chagas, Fiocruz, Rio de Janeiro, Brazil Jamile Garcia de Oliveira and João Marine Clínica de Saúde Rinaldo Delmare, Rio de Janeiro, Brazil Adriana Rezende and Anna Cristina Carvalho Secretaria de Saúde de Duque de Caxias, Rio de Janeiro, Brazil Michael Rocha and Betânia Nogueira Instituto Brasileiro para Investigação da Tuberculose, Fundação José Silveira, Salvador, Brazil Alexandra Brito and Renata Spener Fundação Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil Megan Turner Vanderbilt University Medical Center, Nashville, USA.

Ante la creciente bibliografía publicada en los últimos años acerca de la historia de la sífilis desde los más distintos puntos de vista (médico, antropológico, social, lexicográfico y literario), el presente artículo pretende reivindicar el interés de las referencias del Cancioneiro Geral a la epidemia de esta enfermedad que asola Europa a finales del siglo xv. En la compilación lusa se encuentran, de hecho, los primeros registros de algunas de sus denominaciones eufemísticas en portugués y castellano con base en el campo semántico de los tocados. Así, en una composición colectiva que podemos fechar en 1498, varios autores se burlan aparentemente de una gangorra (o gran gorra) castellana, aludiendo, de modo más o menos velado, al origen de tal mal venéreo, que localizan en el Rosellón, a sus vías de transmisión y a sus síntomas. Por primera vez, establecemos aquí un diálogo intertextual entre estos y otros versos recogidos por Garcia de Resende con tratados científico-divulgativos de la misma época, como el dedicado a las «pestíferas bubas» del médico López de Villalobos, escrito también en 1498.

Application of confocal laser microscopy for identification of modern and fossil pollen grains, an example in palm Mauritiinae

It is a common place in the literature devoted to princess Olga to state that folklore motifs are widely used in her depiction in the Old Russian chronicles. They are found in the narrations about Olga’s revenges the murder of her husband, prince Igor’ on the Drevljans and about the wooing of the Byzantine emperor in the entry telling about her voyage to Constantinople and her baptism there. Since the 19th century these narratives were dealt with separately as independent tales. Olga’s revenges attracted more attention as their folklore background was more obvious which was pointed out already by N. I. Kostomarov in the 1860s who showed their resemblance to the fairy tales. M. I. Sukhomlinav, as later A. Stender-Petersen, E. A. Rydzevskaja, I. Garcia de la Puentes searched for and found many parallels in European as well as in Indo-European narrative traditions. Archaeologists (B. A. Rybakov, et al.) noted connections between the forms of the Olga’s revenges with the burial rites current in the 10th century Rus’. More thorough were the literary studies of the revenge narratives. They reliably established the connection of the revenge tales with the motifs of fairy tales. These studies, however, do not exhaust possible direction of further studies of both the revenge tales and the ensemble of chronicle narratives about Olga with folklore background.

O artigo tenciona analisar a cantiga galegoportuguesa “Dona Ouroana, pois já besta havedes” (B 1499, V 1109), de João Garcia de Guilhade, importante trovador português que frequentou a corte de D. Afonso X. Aproveitando elementos presentes na fortuna crítica, a interpretação proposta argumenta em favor da inscrição definitiva da cantiga no corpus medieval galego-português que trata de mulheres que, nos tempos atuais, poderiam ser qualificadas como “lésbicas”.

Archaeometry of tiles (azulejos) produced in the region of Lisbon – 16th to 18th centuries. A comparison of Lisbon and Seville pastes for the cuerda seca and arista tiles

A Hero Forgotten:Gus Garcia and the Litigation of Hernandez v. Texas (1954) Gabriel Valle (bio) In 1951, in the east end of Jackson County, Texas, if Mexican-American attorney Gus Garcia had attempted to stop by the local restaurant for lunch before his next trial, he would have been greeted with a sign reading "No Mexicans Served."1 When Garcia walked into the Jackson County courtroom to defend his client Pete Hernandez, on trial for the murder of Joe Espinoza, he would have been greeted by a sea of white faces on the jury.2 Finally, should Garcia have needed to use the restroom at the courthouse, there would have been two available; one room unmarked, and the other with two signs above reading "Colored men" and "Hombres Aqui."3 Gustavo 'Gus' Garcia lived amongst and advocated against these pervasive reminders that, to white Texans, Mexican Americans were distinct and decidedly second-class citizens. As a young and promising Mexican-American civil rights attorney, Garcia took it upon himself to challenge these injustices. The talented attorney's trailblazing impact on Mexican-American civil rights deserves wider recognition.4 His dedication to Mexican-American civil rights transformed a local open-and-shut murder case with an unsympathetic plaintiff and factual deficiencies into a brief but national reckoning on Mexican-American civil rights. A Cantina, A Gun, and An Opportunity Although Gus Garcia rocketed to national fame during the Hernandez case, he was already a respected San Antonio attorney when Pete Hernandez initially approached him seeking representation.5 By all accounts, Garcia was a prodigy. A native Texan, Garcia was born in Laredo to one of the state's oldest families, which first settled there in 1765.6 Garcia graduated valedictorian of his high school class, going on to study at the [End Page 31] University of Texas at Austin and became the first Mexican-American debate team captain.7 Garcia graduated in 1936, and received his LL.B. at the University of Texas at Austin two years later.8 After graduation, Garcia initially served as an assistant San Antonio city attorney, followed by a stint as an assistant criminal district attorney. When the U.S. entered World War II, Garcia served in the Pacific Theater, earning the rank of First Lieutenant and serving as a Judge Advocate General in Yokohama, Japan.9 After the war, Garcia returned to Texas and began to make a name for himself. He possessed an "awesome eloquence," in both Spanish and English, allowing him to enrapture courtrooms and crowds alike as he simultaneously nurtured a career in the law and speaking on behalf of local Mexican-American candidates for public office.10 Anywhere Garcia went in Texas, the local attorneys and Mexican-American population would praise this "brilliant" young attorney, who possessed "one of the finest legal minds anywhere."11 It was Garcia's work on Delgado v. Bastrop ISD in 1949 that established him as a preeminent Mexican-American civil rights attorney. Delgado was a challenge to Mexican-American school segregation in Texas. The case went before Judge Ben H. Rice on the U.S. District Court for the Western District of Texas. Judge Rice's ruling ordered a permanent injunction from the "segregating of pupils of Mexican or other Latin American dissent in separate schools," as well as in "facilities and services."12 The injunction did allow, however, for separate classes within the same school for first grade students, "solely for instructional purposes," especially if the Click for larger view View full resolution Delgado v. Bastrop ISD (1949) was a successful challenge to Mexican-American school segregation in Texas, although it allowed for some separate classroom instruction. Gustavo "Gus" Garcia (right) made his name litigating that case, along with Hector P. Garcia and Hector de Pena (left and middle). [End Page 32] student's English was not sufficient.13 A full five years before Brown, Garcia had won a watershed school desegregation victory, chipping away at Texas Mexican-American school segregation. Hearing of Garcia's reputation as an attorney and champion for his people, the twenty-six-year-old Hernandez sought him out for representation. The facts were not promising. On February 23...

ABSTRACT This research aims to investigate the pronunciation of the stressed mid vowels in Portuguese of the 13th, 15th, 16th and 17th centuries, through the observation of the rhymes of the poetry from that period. The corpora comprise the Cantigas de Santa Maria by Alfonso X, the Cancioneiro Geral by Garcia de Resende, Os Lusíadas by Camões and the sonnets by Gregório de Matos. Knowing that the ancient writing, like the present, had only two graphemes to represent phonemes concerning stressed mid vowels of Portuguese, the possibilities and impossibilities of rhyme between mid vowels represented by identical graphemes were evaluated in this work. The results of this research suggest that there was constant phonetic variation in the speech of the stressed mid vowels of the Portuguese language, between the 15th and 17th centuries (at least), and that, in some cases, this variation resulted in a change, throughout the history of the language.

The postmodern historical novel “The Broken Emerald” is the most multifaceted work by the Portuguese author Fernando Campos, which reveals the differences in the opinion of winners and losers of the Age of Exploration under the rule of King John II, presented to the reader by the viewpoint of Garcia de Resende, a court chronicler. Campos’ work is a part of tetralogy, dedicated to the rise and fall of the Portuguese Empire. The article focuses on the emotions, evoked by the imaginary dialogue between the Renaissance chronicler Garcia de Resende and the spirit of the recently deceased monarch, which reveals the reasons for the decline of the Empire and the loss of the independence. The paper is concentrated on the narrator’s subjective feelings and their gradual unfolding in the narrative, which help to construct a multidimensional and multi-sided rereading of a key period in Portuguese history.

Jonathan William Wade. <i>Being Portuguese in Spanish: Reimagining Early Modern Iberian Literature, 1580–1640</i>

In this paper, we extend Shaposhnikov et al.'s parity violating the Einstein–Cartan–Holst action by adding to Holst term H, a Proca photon–torsion coupling χpt = 10−24 as computed by De Sabbata, Garcia de Andrade, and Sivaram. The strength of Holst term is obtained, in the case of early universe torsion as, T ∼ 1 MeV. The gravity part is the Planck mass product with the Holst term. The photon mass in this case yields m2 γ H ∼ 10−69 GeV4. Therefore, in this case, the photon interacts very weakly with spin-torsion matter in Einstein–Cartan (EC) gravity and the strength of the Maxwell–Proca–Holst interaction is much weaker than in the pure gravity sector. For dark photons, this situation changes drastically since a dark photon mass reaches 1.5 GeV, and from this mass and T = 10−3 GeV, one obtains a Maxwell–Proca–Holst strength of 10−6 GeV4, which is now comparable with the gravity sector. Dynamo mechanism competes with the chirality and dissipation by the handness of the magnetic field with respect to the torsion trace vector to regenerate the magnetic field decay. Bombacigno and Mantovani recently found a sign of the Immirzi parameter in the Holst–Nieh–Yan extension of EC gravity. Here, we also find torsion waves for the Immirzi inverse parameter in the sense that this divergence of torsion trace is porportional to the Immirzi field.

Recently, presence of gravitational and axial anomalies in Riemann–Cartan (RC) spacetime [Garcia de Andrade, Class. Quantum Gravity 38 (2021)] indicates that topological densities expressed in terms of torsion may be very useful in understanding the physics involved. Pontryagin and Euler density may be presented in terms of torsion in teleparallelism. In this paper, computation of these topological torsional densities in Kerr black holes is given. The geometric quantisation of torsion is also discussed in terms of the teleparallel metric. Actually, the recent work of Del Grosso and Poplawski [arXiv: 2107.06112] showed that the torsion quantization appears when torsion is the generator of momentum quantum mechanical commutator. Moreover, Poplawski et al. showed that use of quantum torsion in quantum electrodynamic (QED) may avoid the divergences in Feynmann integrals, process called, a torsion regularization. Here, we compute the momenta components in terms of teleparallel Kerr black hole torsion generator, like a Casimir tensor. The quantum generator, while not yet related by torsion, is seen to be naturally associated to axial torsion skew-symmetric in the teleparallel geometry. An important fact is that from torsion quantization, torsion chirality appears naturally in the Einstein–Cartan spin-torsion analogy, where now spin-angular momentum of the black hole is connected to torsion. Torsional chiral anomalies are shown to diverge at black hole singularity, and then they cannot be canceled at singularity.

In this paper, spin polarized domain walls in Einstein–Cartan (EC) gravity have been recently investigated [L. C. Garcia de Andrade, Einstein–Cartan non-supersymmetric dynamo walls, Ann. Phys. 432 (2021).], where the spin polarizes along the direction orthogonal to planar domain wall. In this case, dynamo effects may appear on the wall. Moreover, dilatonic domain walls (DDWs) have shown to be responsible for inflating DWs in EC gravity, where DWs were non-magnetized [L. Garcia de Andrade, Axial and chiral anomalies in Riemann–Cartan spacetime black holes and electrodynamics, Class. Quantum Grav. 16 (1999) 2097–2103.]. In this paper, our goal is to show that when we consider a magnetized DW in the EC–Maxwell cosmology, the dilaton potential in the form of a DDW potential expressed in terms of torsion and the magnetic energy density may drive dynamo effects. Analytical solution of the dynamo equation shows that depending on the handness of DDW metric, the magnetic fields are amplified by dynamo action. From the coupled system of ECM and dilaton field equations, we find a relation between the magnetic energy density of [Formula: see text] and the DDW torsion of [Formula: see text] which leads to a thin DDW thickness of [Formula: see text]. For a galactic magnetic field, energy density of [Formula: see text] leads to a thickness of [Formula: see text], a much thinner DDW. For galactic dynamo amplification, the ratio r between the magnetic energy density and photon energy density is around [Formula: see text]. From this ratio, a relation between photon mass density and torsion is obtained. Chiral Magnetic effect (CME), torsion and magnetic discontinuities along the wall are investigated. Magnetic field discontinuity across the wall allows us to understand why the magnetic fields at DDW must be located along the wall since the orthogonal magnetic field may vanish.