Gain Correction Method Research Articles

Improving the X-Ray Energy Resolution of a Scientific CMOS Detector by Pixel-level Gain Correction

Scientific Complementary Metal Oxide Semiconductor (sCMOS) sensors are finding increasingly more applications in astronomical observations, thanks to their advantages over charge-coupled devices such as a higher readout frame rate, higher radiation tolerance, and higher working temperature. In this work, we investigate the performance at the individual pixel level of a large-format sCMOS sensor, GSENSE1516BSI, which has 4096 × 4096 pixels, each of 15 μm in size. To achieve this, three areas on the sCMOS sensor, each consisting of 99 × 99 pixels, are chosen for the experiment. The readout noise, conversion gain and energy resolutions of the individual pixels in these areas are measured from a large number (more than 25,000) of X-ray events accumulated for each of the pixels through long time exposures. The energy resolution of these pixels can reach 140 eV at 6.4 keV at room temperature and shows a significant positive correlation with the readout noise. The accurate gain can also be derived individually for each of the pixels from its X-ray spectrum obtained. Variations of the gain values are found at a level of 0.56% statistically among the 30 thousand pixels in the areas studied. With the gain of each pixel determined accurately, a precise gain correction is performed pixel by pixel in these areas, in contrast to the standardized ensemble gain used in the conventional method. In this way, we could almost completely eliminate the degradation of energy resolutions caused by gain variations among pixels. As a result, the energy resolution at room temperature can be significantly improved to 124.6 eV at 4.5 keV and 140.7 eV at 6.4 keV. This pixel-by-pixel gain correction method can be applied to all kinds of CMOS sensors, and is expected to find interesting applications in X-ray spectroscopic observations in the future.

Strong Adaptability Control Based on Dual-Division-Summation Current Control for an LCL-Type Grid-Connected Inverter

The nonignorable grid impedance is one of the characteristics of a weak grid. Meanwhile, the filter inductance also fluctuates with temperature or aging factors. The resonant frequency offset of an <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">LCL</i> filter will be caused by the change in power grid impedance and filter inductance. To this end, a strong adaptability control based on dual-division-summation (D-D-Σ) control is proposed in this article, which considers both the accuracy of grid-connected current tracking and resonance suppression under the variation of grid impedance and filter inductance. A full inductance parameter identification method based on an extended Kalman filter for simultaneously estimating filter inductance and grid impedance is proposed without remote voltage sampling. An enumeration method of the Routh array with less calculation is proposed. The algebraic relationship between control parameters and total inductance parameters is obtained by the Routh criterion. A gain correction method to realize strong adaptive control is proposed to deal with the variation of grid impedance and filter inductance. The experimental results prove the feasibility of D-D-Σ control in a three-phase <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">LCL</i> -type grid-connected inverter under the variation of grid impedance and filter inductance.

Evaluation of detector readout gain mode and bowtie filters for cone-beam CT imaging of the head

The effects of detector readout gain mode and bowtie filters on cone-beam CT (CBCT) image quality and dose were characterized for a new CBCT system developed for point-of-care imaging of the head, with potential application to diagnosis of traumatic brain injury, intracranial hemorrhage (ICH), and stroke.A detector performance model was extended to include the effects of detector readout gain on electronic digitization noise. The noise performance for high-gain (HG), low-gain (LG), and dual-gain (DG) detector readout was evaluated, and the benefit associated with HG mode in regions free from detector saturation was quantified. Such benefit could be realized (without detector saturation) either via DG mode or by incorporation of a bowtie filter. Therefore, three bowtie filters were investigated that varied in thickness and curvature. A polyenergetic gain correction method was developed to equalize the detector response between the flood-field and projection data in the presence of a bowtie. The effect of bowtie filters on dose, scatter-to-primary ratio, contrast, and noise was quantified in phantom studies, and results were compared to a high-speed Monte Carlo (MC) simulation to characterize x-ray scatter and dose distributions in the head.Imaging in DG mode improved the contrast-to-noise ratio (CNR) by ~15% compared to LG mode at a dose (D0, measured at the center of a 16 cm CTDI phantom) of 19 mGy. MC dose calculations agreed with CTDI measurements and showed that bowtie filters reduce peripheral dose by as much as 50% at the same central dose. Bowtie filters were found to increase the CNR per unit square-root dose near the center of the image by ~5–20% depending on bowtie thickness, but reduced CNR in the periphery by ~10–40%. Images acquired at equal CTDIw with and without a bowtie demonstrated a 24% increase in CNR at the center of an anthropomorphic head phantom. Combining a thick bowtie filter with a short arc (180° + fan angle) scan centered on the posterior of the head reduced dose to the eye lens by up to 90%.Acquisition in DG mode (without a bowtie filter) was beneficial to the detection of small, low contrast lesions (e.g. subtle ICH) in CBCT. While bowtie filters were found to reduce dose, mitigate sensor saturation at the periphery in HG mode, and improve CNR at the center of the image, the image quality at the periphery was slightly reduced compared to DG mode, and the use of a bowtie required careful implementation of the polyenergetic flood-field correction to avoid artifacts.

SU‐F‐T‐180: Evaluation of a Scintillating Screen Detector for Proton Beam QA and Acceptance Testing

Purpose:To test the performance of a commercial scintillating screen detector for acceptance testing and Quality Assurance of a proton pencil beam scanning system.Method:The detector (Lexitek DRD 400) has 40cm × 40cm field, uses a thin scintillator imaged onto a 16‐bit scientific CCD with ∼0.5mm resolution. A grid target and LED illuminators are provided for spatial calibration and relative gain correction. The detector mounts to the nozzle with micron precision. Tools are provided for image processing and analysis of single or multiple Gaussian spots.Results:The bias and gain of the detector were studied to measure repeatability and accuracy. Gain measurements were taken with the LED illuminators to measure repeatability and variation of the lens‐CCD pair as a function with f‐stop. Overall system gain was measured with a passive scattering (broad) beam whose shape is calibrated with EDR film placed in front of the scintillator. To create a large uniform field, overlapping small fields were recorded with the detector translated laterally and stitched together to cover the full field. Due to the long exposures required to obtain multiple spills of the synchrotron and very high detector sensitivity, borated polyethylene shielding was added to reduce direct radiation events hitting the CCD. Measurements with a micro ion chamber were compared to the detector's spot profile. Software was developed to process arrays of Gaussian spots and to correct for radiation events.Conclusion:The detector background has a fixed bias, a small component linear in time, and is easily corrected. The gain correction method was validated with 2% accuracy. The detector spot profile matches the micro ion chamber data over 4 orders of magnitude. The multiple spot analyses can be easily used with plan data for measuring pencil beam uniformity and for regular QA comparison.

A robust strong tracking cubature Kalman filter for spacecraft attitude estimation with quaternion constraint

This paper considers a robust strong tracking nonlinear filtering problem in the case there are model uncertainties including the model mismatch, unknown disturbance and status mutation in the spacecraft attitude estimation system with quaternion constraint. Two multiple fading factor matrices are employed to regulate the prediction error covariance matrix, which guarantees its symmetry. The spherical-radial cubature rule is developed to deal with the multi-dimensional integrals. The quaternion constraint is maintained by utilizing the gain correction method. Therefore a robust strong tracking cubature Kalman filter (RSTCKF) is formed for the spacecraft attitude estimation with quaternion constraint. Unlike adopting a single fading factor in the traditional strong tracking filter, the presented filter uses two multiple fading factor matrices to make different channels have respective filter adjustment capability, which improves the tracking performance of this algorithm. Simulation results show the effectiveness of the proposed RSTCKF.

Gain Correction for an X-ray Imaging System With a Movable Flat Panel Detector and Intrinsic Localization Crosshair.

Gain calibration for X-ray imaging systems with a movable flat panel detector and an intrinsic crosshair is a challenge due to the geometry-dependent heel effect and crosshair artifact. This study aims to develop a gain correction method for such systems by implementing the Multi-Acquisition Gain Image Correction technique. Flood field images containing crosshair and heel effect were acquired in 4 different flat panel detector positions at fixed exposure parameters. The crosshair region was automatically detected using common image processing algorithms and removed by a simple interpolation procedure, resulting in a crosshair-removed image. A large kernel-based correction was then used to remove the heel effect. Mask filters corresponding to each crosshair region were applied to the resultant heel effect-removed images to invalidate the pixels of the original crosshair region. Finally, a seamless gain map was composed with corresponding valid pixels from the processed images either by the sequential replacement or by the selective averaging techniques developed in this study. Quantitative evaluation was performed based on normalized noise power spectrum and detective quantum efficiency improvement factor for the flood field images corrected by the Multi-Acquisition Gain Image Correction-based gain maps. For comparison purposes, a single crosshair-removed gain map was also tested. As a result, it was demonstrated that the Multi-Acquisition Gain Image Correction technique achieved better image quality than the crosshair-removed technique, showing lower normalized noise power spectrum values over most of spatial frequencies. The improvement was more obvious at the priori-crosshair region of the gain map. The mean detective quantum efficiency improvement factor was 1.09 ± 0.06, 2.46 ± 0.32, and 3.34 ± 0.36 in the priori-crosshair region and 2.35 ± 0.31, 2.33 ± 0.31, and 3.09 ± 0.34 in the normal region, for crosshair-removed, Multi-Acquisition Gain Image Correction-sequential replacement, and Multi-Acquisition Gain Image Correction-selective averaging techniques, respectively. Therefore, this study indicates that the introduced Multi-Acquisition Gain Image Correction technique is an appropriate method for gain calibration of an imaging system associated with a moving flat panel detector and an intrinsic crosshair.

WE-G-18A-02: Calibration-Free Combined KV/MV Short Scan CBCT

Purpose: To combine orthogonal kilo-voltage (kV) and Mega-voltage (MV) projection data for short scan cone-beam CT to reduce imaging time on current radiation treatment systems, using a calibration-free gain correction method. Methods: Combining two orthogonal projection data sets for kV and MV imaging hardware can reduce the scan angle to as small as 110° (90°+fan) such that the total scan time is ∼18 seconds, or within a breath hold. To obtain an accurate reconstruction, the MV projection data is first linearly corrected using linear regression using the redundant data from the start and end of the sinogram, and then the combined data is reconstructed using the FDK method. To correct for the different changes of attenuation coefficients in kV/MV between soft tissue and bone, the forward projection of the segmented bone and soft tissue from the first reconstruction in the redundant region are added to the linear regression model. The MV data is corrected again using the additional information from the segmented image, and combined with kV for a second FDK reconstruction. We simulated polychromatic 120 kVp (conventional a-Si EPID with CsI) and 2.5 MVp (prototype high-DQE MV detector) projection data with Poisson noise using the XCAT phantom. The gainmore » correction and combined kV/MV short scan reconstructions were tested with head and thorax cases, and simple contrast-to-noise ratio measurements were made in a low-contrast pattern in the head. Results: The FDK reconstruction using the proposed gain correction method can effectively reduce artifacts caused by the differences of attenuation coefficients in the kV/MV data. The CNRs of the short scans for kV, MV, and kV/MV are 5.0, 2.6 and 3.4 respectively. The proposed gain correction method also works with truncated projections. Conclusion: A novel gain correction and reconstruction method was developed to generate short scan CBCT from orthogonal kV/MV projections. This work is supported by NIH Grant 5R01CA138426-05.« less

WE-E-18A-07: MAGIC: Multi-Acquisition Gain Image Correction for Mobile X-Ray Systems with Intrinsic Localization Crosshairs

Purpose: Gain calibration for X-ray imaging systems with movable flat panel detectors (FPD) and intrinsic crosshairs is a challenge due to the geometry dependence of the heel effect and crosshair artifact. This study aims to develop a gain correction method for such systems by implementing the multi-acquisition gain image correction (MAGIC) technique. Methods: Raw flat-field images containing crosshair shadows and heel effect were acquired in 4 different FPD positions with fixed exposure parameters. The crosshair region was automatically detected and substituted with interpolated values from nearby exposed regions, generating a conventional single-image gain-map for each FPD position. Large kernel-based correction was applied to these images to correct the heel effect. A mask filter was used to invalidate the original cross-hair regions previously filled with the interpolated values. A final, seamless gain-map was created from the processed images by either the sequential filling (SF) or selective averaging (SA) techniques developed in this study. Quantitative evaluation was performed based on detective quantum efficiency improvement factor (DQEIF) for gain-corrected images using the conventional and proposed techniques. Results: Qualitatively, the MAGIC technique was found to be more effective in eliminating crosshair artifacts compared to the conventional single-image method. The mean DQEIF over the range of frequencies from 0.5 to 3.5 mm-1 were 1.09±0.06, 2.46±0.32, and 3.34±0.36 in the crosshair-artifact region and 2.35±0.31, 2.33±0.31, and 3.09±0.34 in the normal region, for the conventional, MAGIC-SF, and MAGIC-SA techniques, respectively. Conclusion: The introduced MAGIC technique is appropriate for gain calibration of an imaging system associated with a moving FPD and an intrinsic crosshair. The technique showed advantages over a conventional single image-based technique by successfully reducing residual crosshair artifacts, and higher image quality with respect to DQE.

Technical Note: Modification of the standard gain correction algorithm to compensate for the number of used reference flat frames in detector performance studies

The x-ray performance evaluation of digital x-ray detectors is based on the calculation of the modulation transfer function (MTF), the noise power spectrum (NPS), and the resultant detective quantum efficiency (DQE). The flat images used for the extraction of the NPS should not contain any fixed pattern noise (FPN) to avoid contamination from nonstochastic processes. The "gold standard" method used for the reduction of the FPN (i.e., the different gain between pixels) in linear x-ray detectors is based on normalization with an average reference flat-field. However, the noise in the corrected image depends on the number of flat frames used for the average flat image. The aim of this study is to modify the standard gain correction algorithm to make it independent on the used reference flat frames. Many publications suggest the use of 10-16 reference flat frames, while other studies use higher numbers (e.g., 48 frames) to reduce the propagated noise from the average flat image. This study quantifies experimentally the effect of the number of used reference flat frames on the NPS and DQE values and appropriately modifies the gain correction algorithm to compensate for this effect. It is shown that using the suggested gain correction algorithm a minimum number of reference flat frames (i.e., down to one frame) can be used to eliminate the FPN from the raw flat image. This saves computer memory and time during the x-ray performance evaluation. The authors show that the method presented in the study (a) leads to the maximum DQE value that one would have by using the conventional method and very large number of frames and (b) has been compared to an independent gain correction method based on the subtraction of flat-field images, leading to identical DQE values. They believe this provides robust validation of the proposed method.

Real-time gain correction method using a reference light for an area-parallel-type frame-transfer charge-coupled device with multi-output taps

The authors propose a technique for performing real-time correction of the gain nonuniformity at output taps in an area-parallel-type frame transfer CCD (FT-CCD) by incorporating a reference optical signal. This technique activates a reference light source every vertical blanking (V-blanking) period, during which time the image sensor is shielded from incident light, and uses that output signal level to automatically adjust the gain of each block. For this method, a color-separation prism with reference light sources has been developed. In addition, to obtain a reference signal from the reference light source emitting for about 11% of the V-blanking period, a new method of accumulating the electron signal generated by the reference light source is described for the CCD. The results of a camera experiment using an 8-million-pixel CCD are described, and the compensation accuracy of this method is discussed.