Mass-injection experiments in space plasmas have been conducted for the last twenty years. These injections trace or stain chemical or physical processes, facilitating diagnosis of the natural state of the space plasma; artificially perturb the space plasma away from equilibrium, isolating and controlling selected parameters; simulate natural or artificial states of space plasmas; and utilize the advantages of space as a laboratory to study fundamental plasma physics. We use the Lagopedo ionospheric-depletion experiments to illustrate the special operational aspects of active experiments, including weather, logistics, communications, and real-time diagnostics. The various objectives and techniques of mass-injection experiments are described by example. The CAMEO experiment, a thermite barium release from a satellite over the nightside polar cap, is an excellent example of the use of barium injections to trace upward ion acceleration. The Periquito Dos experiment provided a “snapshot” view of convection electric fields in the dayside polar cusp region. Project Waterhole, an artificial depletion of the topside auroral ionosphere, attempted to modify the equilibrium character of the field-aligned currents and apparently shut off the aurora in a small space-time volume. The Trigger experiment is another example of an active perturbation experiment, wherein the auroral ionospheric transverse conductivities were modified via a cesium injection. The Buaro experiment, a shaped-charged barium injection perpendicular to the local geomagnetic field, resulted in an ion-beam/background-plasma system being displaced from equilibrium, permitting diagnostics of collisionless coupling of the ion beam to the background plasma.
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