Frontal Surface Area Research Articles

Morphology of the prefrontal cortex predicts body composition in early adolescence: cognitive mediators and environmental moderators in the ABCD Study.

Morphological features of the lateral prefrontal cortex (PFC) in late childhood and early adolescence may provide important clues as to the developmental etiology of clinical conditions such as obesity. Body composition measurements and structural brain imaging were performed on 11 226 youth at baseline (age 9 or 10 years) and follow-up (age 11 or 12 years). Baseline morphological features of the lateral PFC were examined as predictors of body composition. Findings revealed reliable associations between middle frontal gyrus volume, thickness and surface area and multiple indices of body composition. These findings were consistent across both time points and remained significant after covariate adjustment. Cortical thicknesses of the inferior frontal gyrus and lateral orbitofrontal cortex were also reliable predictors. Morphology effects on body composition were mediated by performance on a non-verbal reasoning task. Modest but reliable moderation effects were observed with respect to environmental self-regulatory demand after controlling for sex, race/ethnicity, income and methodological variables. Overall findings suggest that PFC morphology is a reliable predictor of body composition in early adolescence, as mediated through select cognitive functions and partially moderated by environmental characteristics.

Personality and local brain structure: Their shared genetic basis and reproducibility

Local cortical architecture is highly heritable and distinct genes are associated with specific cortical regions. Total surface area has been shown to be genetically correlated with complex cognitive capacities, suggesting cortical brain structure is a viable endophenotype linking genes to behavior. However, to what extend local brain structure has a genetic association with cognitive and emotional functioning is incompletely understood. Here, we study the genetic correlation between personality traits and local cortical structure in a large-scale twin sample (Human Connectome Project, n ​= ​1102, 22-37y) and we evaluated whether observed associations reflect generalizable relationships between personality and local brain structure two independent age-matched samples (Brain Genomics Superstructure Project: n ​= ​925, age ​= ​19-35y, enhanced Nathan Kline Institute dataset: n ​= ​209, age: 19-39y). We found a genetic overlap between personality traits and local cortical structure in 10 of 18 observed phenotypic associations in predominantly frontal cortices. However, we only observed evidence in favor of replication for the negative association between surface area in medial prefrontal cortex and Neuroticism in both replication samples. Quantitative functional decoding indicated this region is implicated in emotional and socio-cognitive functional processes. In sum, our observations suggest that associations between local brain structure and personality are, in part, under genetic control. However, associations are weak and only the relation between frontal surface area and Neuroticism was consistently observed across three independent samples of young adults.

Assessing the Role of Cannabis Use on Cortical Surface Structure in Adolescents and Young Adults: Exploring Gender and Aerobic Fitness as Potential Moderators.

Cannabis use in adolescents and young adults is linked with aberrant brain structure, although findings to date are inconsistent. We examined whether aerobic fitness moderated the effects of cannabis on cortical surface structure and whether gender may play a moderating role. Seventy-four adolescents and young adults completed three-weeks of monitored abstinence, aerobic fitness testing, and structural magnetic resonance imaging (sMRI). Whole-sample linear regressions examined the effects of gender, VO2 max, cannabis use, and their interactions on the surface area (SA) and local gyrification index (LGI). Cannabis use was associated with greater cuneus SA. Gender-by-cannabis predicted precuneus and frontal SA, and precentral, supramarginal, and frontal LGI; female cannabis users demonstrated greater LGI, whereas male cannabis users demonstrated decreased LGI compared to non-users. Aerobic fitness was positively associated with various SA and LGI regions. Cannabis-by-aerobic fitness predicted cuneus SA and occipital LGI. These findings demonstrate that aerobic fitness moderates the impact of cannabis on cortical surface structure, and gender differences are evident. These moderating factors may help explain inconsistencies in the literature and warrant further investigation. Present findings and aerobic fitness literature jointly suggest aerobic intervention may be a low-cost avenue for improving cortical surface structure, although the impact may be gender-specific.

Early childhood deprivation is associated with alterations in adult brain structure despite subsequent environmental enrichment

Early childhood deprivation is associated with higher rates of neurodevelopmental and mental disorders in adulthood. The impact of childhood deprivation on the adult brain and the extent to which structural changes underpin these effects are currently unknown. To investigate these questions, we utilized MRI data collected from young adults who were exposed to severe deprivation in early childhood in the Romanian orphanages of the Ceaușescu era and then, subsequently adopted by UK families; 67 Romanian adoptees (with between 3 and 41 mo of deprivation) were compared with 21 nondeprived UK adoptees. Romanian adoptees had substantially smaller total brain volumes (TBVs) than nondeprived adoptees (8.6% reduction), and TBV was strongly negatively associated with deprivation duration. This effect persisted after covarying for potential environmental and genetic confounds. In whole-brain analyses, deprived adoptees showed lower right inferior frontal surface area and volume but greater right inferior temporal lobe thickness, surface area, and volume than the nondeprived adoptees. Right medial prefrontal volume and surface area were positively associated with deprivation duration. No deprivation-related effects were observed in limbic regions. Global reductions in TBV statistically mediated the observed relationship between institutionalization and both lower intelligence quotient (IQ) and higher levels of attention deficit/hyperactivity disorder symptoms. The deprivation-related increase in right inferior temporal volume seemed to be compensatory, as it was associated with lower levels of attention deficit/hyperactivity disorder symptoms. We provide compelling evidence that time-limited severe deprivation in the first years of life is related to alterations in adult brain structure, despite extended enrichment in adoptive homes in the intervening years.

A Solid-State Gas Generator Actuated Deorbiter for CubeSats

A solid-state actuated deorbiter for SmallSats and CubeSats has been developed, the Solid State Inflation Balloon deobriter (SSIB). The device reduces orbital lifetime by increasing the frontal surface area of spacecraft and thereby increasing drag in the upper atmosphere Surface area is increased by inflating a gossamer inflation balloon and this method can reduce orbital lifetime by over an order of magnitude, dependent on the size of the balloon. The balloon in inflated with a custom MEMS device, the Solid-State Gas Generator (SSGG), which creates dry Nitrogen gas on-demand by thermally decomposing Sodium Azide crystals. The SSGG consists of an array of individually addressable micro-heaters which provide the thermal energy to generate gas. The SSIB was developed and prototyped at the University of Arkansas under a development grant from NASA. Prototypes were tested at NASA Ames’ Research Center and successfully passed thermal, vibrational, shock, and vacuum deployment testing.

Structure related to function: prefrontal surface area has an indirect effect on the relationship between amygdala volume and trait neuroticism.

Trait neuroticism refers to individual differences in negative emotional response to threat, frustration, or loss, operationally defined by elevated levels of irritability, anger, sadness, anxiety, worry, hostility, self-consciousness, and vulnerability to mental and physical difficulties. While functional studies have been fairly consistent when identifying regions associated with neuroticism during emotional stimuli, structural imagining studies do not tend to find a relationship between amygdala volume and trait neuroticism. There is a great deal of functional evidence that frontoparietal areas are related to the amygdala, and to emotional reactivity more generally, as a function of their involvement in emotion regulation. Specifically, top-down emotion appraisal and expression appear to involve parts of the dorsolateral and dorsomedial prefrontal cortices, which operate at least in part via the indirect modulation of the amygdala. It was hypothesized that cortical surface area and cortical thickness in regions associated with emotion appraisal/expression and emotional attention (i.e., superior frontal and rostral middle frontal gyri, respectively) would have an indirect effect on the relationship between amygdala volume and self-reported neuroticism (respectively), potentially explaining the inconsistency in the structural literature. In sample of 1106 adults, superior frontal and rostral middle frontal gyri, as parcellated by Freesurfer, were examined as potentially restricting variance in a model of indirect effects, which may elucidate the overall relationship between cortical and subcortical gray matter volume and trait neuroticism. Results indicated that, despite no association between bilateral amygdala volume and trait neuroticism, when right superior frontal surface area was entered into the model of indirect effects, a significant relationship between amygdala volume and trait neuroticism emerged. Two of the three remaining models indicated that cortical surface area had an indirect effect on the relationship between amygdala volume and trait neuroticism. These findings highlight the relationship between structural and functional neuroimaging studies. Specifically, the results indicate that when volume is related to behavior, individual differences in higher-order cortical regions, particularly surface area, may help to better understand the relationship between emotion and subcortical gray matter volume.

Cognitive performance and structural brain correlates in long-term anabolic-androgenic steroid exposed and nonexposed weightlifters.

To test for associations between long-term anabolic-androgenic steroid (AAS) use and cognitive functioning, and establish a candidate neuronal basis by assessing the associations between cognitive performance and brain morphology both in users and nonusers. Eighty four previous or current AAS-users and 69 non-AAS-using male weightlifters aged 19-75 years (mean 32.6, SD 8.8) underwent MRI of the brain and a comprehensive neuropsychological test battery. Performance on fine motor speed, speed of processing, learning and memory, working memory, executive functioning, and problem solving was compared between the groups, and between AAS users with short versus long AAS exposure. Associations between cognitive scores and regional cortical thickness and arealization defined using FreeSurfer were tested using linear models. Relative to nonexposed, AAS-exposed weightlifters performed significantly worse on several cognitive domains, independent of age, education, verbal IQ, and exposure to classical drugs of abuse. Strongest effects were observed for speed of processing (ηp2 = .07), working memory (ηp2 = .08) and problem solving (ηp2 = .09). Longer duration of AAS-use was associated with poorer memory function (ηp2 = .11). Within AAS users, individuals with better memory and working memory performance had with thicker frontoparietal cortex and larger medial frontal surface area, respectively. Prolonged high-dose AAS use is associated with poorer cognitive function across multiple domains, and the observed regional associations between cortical brain morphometry and memory and working memory performance may suggest differential brain-based mechanisms. The public, health care professionals, and policymakers should be aware that use of AAS in large doses potentially could lead to poorer brain health and cognition. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Statistical Analysis on The Geometric, Physical and Mechanical Properties of Dried Robusta Coffee Cherry Resulting From Natural System Processing

The study conducted to evaluate the in-between correlation parameters of size, shape, physical and mechanical properties to provide information of physical and mechanical properties of the dried Robusta coffee cherry in relation with the development of coffee processing equipment. The physical and mechanical properties of the dried cherry were measured. The relationship in-between the physical and mechanical properties was analyzed using the stepwise regression analysis. The results of the study showed that polar diameter, equatorial diameter, thickness, geometrical diameter, arithmetic diameter, and surface area were dependent on volume with the correlation coefficient of 0.738, 0,761, 0.775, 0.994, 0.999 and 0.999 respectively. The sphericity was dependent on bulk density with a correlation coefficient of 0.437. The shape index, cross-sectional area and frontal surface area were dependent on particle density with the correlation coefficient of 0.959, 1.00 and 0.967 respectively. The correlation coefficient of the relationship between static friction and angle of repose on acrylic, stainless steel, and plywood were 0.772, 0.700, 1.000 and 0.930 respectively; otherwise, there was no correlation between the static friction and the filling angle of repose. The hardness of the dried cherry had a weak correlation with the fracturability.

Longitudinal cortical markers of persistence and remission of pediatric PTSD.

Previous studies have identified structural brain abnormalities in pediatric PTSD. However, little is known about what structural brain substrates may confer recovery versus persistence of PTSD in the context of the developing brain. This naturalistic longitudinal study used T1-weighted MRI to evaluate cortical thickness and surface area in youth with a PTSD diagnosis (n = 28) and typically developing healthy youth (TD; n = 27) at baseline and one-year follow-up. Of the PTSD group, 10 youth were remitters at one-year follow up while 18 had persistent PTSD. Whole-brain estimates of cortical thickness and surface area were extracted to identify differences in cortical architecture associated with PTSD remission and persistence as compared to typical development. Youth who achieved PTSD remission entered the study with significantly lower trauma exposure and reduced symptom severity as compared to nonremitters. PTSD persistence was associated with decreased surface area over time in the ventrolateral prefrontal cortex (vlPFC) as compared to both remitters and TD youth. In contrast, PTSD remission was associated with expansion of frontal pole surface area and ventromedial PFC (vmPFC) thickness over time. Across clinical groups, vmPFC thickness was further inversely associated with symptom severity. To our knowledge, these findings represent the first report of cortical substrates underlying persistence versus remission in pediatric PTSD. Together, these findings suggest active structural developmental processes unique to both remission and nonremission in youth with PTSD. In particular, expansion of prefrontal regions implicated in emotion regulation may facilitate recovery from PTSD in youth and would warrant further study.

Larger right inferior frontal gyrus volume and surface area in participants at genetic risk for bipolar disorders.

Larger grey matter volume of the inferior frontal gyrus (IFG) is among the most replicated biomarkers of genetic risk for bipolar disorders (BD). However, the IFG is a heterogeneous prefrontal region, and volumetric findings can be attributable to changes in cortical thickness (CT), surface area (SA) or gyrification. Here, we investigated the morphometry of IFG in participants at genetic risk for BD. We quantified the IFG cortical grey matter volume in 29 affected, 32 unaffected relatives of BD probands, and 42 controls. We then examined SA, CT, and cortical folding in subregions of the IFG. We found volumetric group differences in the right IFG, with the largest volumes in unaffected high-risk and smallest in control participants (F2,192 = 3.07, p = 0.01). The volume alterations were localized to the pars triangularis of the IFG (F2,97 = 4.05, p = 0.02), with no differences in pars opercularis or pars orbitalis. Pars triangularis volume was highly correlated with its SA [Pearson r(101) = 0.88, p < 0.001], which significantly differed between the groups (F2,97 = 4.45, p = 0.01). As with volume, the mean SA of the pars triangularis was greater in unaffected (corrected p = 0.02) and affected relatives (corrected p = 0.05) compared with controls. We did not find group differences in pars triangularis CT or gyrification. These findings strengthen prior knowledge about the volumetric findings in this region and provide a new insight into the localization and topology of IFG alterations. The unique nature of rIFG morphology in BD, with larger volume and SA early in the course of illness, could have practical implications for detection of participants at risk for BD.

Accelerated executive functions decline and gray matter structural changes in middle‐aged type 1 diabetes mellitus patients with proliferative retinopathy

The aim of the present study was to determine trajectories of cognitive and cortical changes over time in middle-aged patients with type 1 diabetes mellitus (T1DM) and proliferative retinopathy. Twenty-five patients and 25 controls underwent neuropsychological assessment and neuroimaging twice in a mean (±SD) of 3.56 ± 0.65 and 3.94 ± 0.91 years, respectively (P = 0.098). Cognitive assessment included the domains of general cognitive ability, memory, information processing speed, executive functions, attention, and motor and psychomotor speed. Symmetrized percentage change in local cortical thickness, surface area, and volume was determined using the FreeSurfer 6 vertex-wise general linear model method. Analyses were performed uncorrected and corrected for baseline systolic blood pressure and depressive symptoms. In patients versus controls, accelerated executive function decline was accompanied by, but not related to, lower left frontal and temporal surface area, left parietal and right frontal thickness, and bilateral frontal and right posterior cingulate volume (family-wise error [FWE]-corrected P < 0.05 for all). In patients, lower executive performance was related to loss of right precuneus surface area (PFWE = 0.005). Higher HbA1c during follow-up was related to executive function decline (r = -0.509, P = 0.016) and loss of left hemisphere surface area (rcorrected analysis = -0.555, P = 0.007). After 3.5 years of follow-up, middle-aged T1DM patients with proliferative retinopathy, mild focal changes in executive functions, and cortical structure were found, which may indicate accelerated aging.

The Development of an Optimal Aerodynamic Design for a Human Powered Vehicle

With growing concerns about air pollution, Human Powered Vehicle (HPV) offers a possible solution. With limited power available from human muscle, HPVs must be as efficient as possible because aerodynamic drag is the dominant retarding force at high speed. Two fairings for the use cases of pure speed and everyday use are conceived, designed, implemented and operated where the key parameters of frontal area, surface area and shape are evaluated and compared with a benchmark model. The fairings are designed using the NACA 65-415, 66-018 and 66-021 airfoils. Computational fluid dynamics (CFD) simulations were done using the realizable k-ɛ model with scalable wall functions. In addition, low-speed comparative wind tunnel testing was conducted using the Taylor’s Wind Tunnel with 1/10 scale models. It was found that the pure speed fairing having the lowest values of frontal and surface area produced the lowest drag, followed by the benchmark model and lastly the everyday use model which has the highest values of the respective parameters. The same trends were found in the wind tunnel. Due to the CFD limitation of not simulating boundary layer transition, the shape parameter could not be evaluated and thus future simulations using the transition SST turbulence model is recommended.

T171. REDUCED FRONTAL CORTICAL THICKNESS AND SURFACE IN A 10 YEARS FOLLOW-UP OF EARLY ONSET PSYCHOSIS

BackgroundStructural volume loss of cortical gray matter over time in schizophrenia has been widely reported (Vita et al. 2012), and may be more pronounced when the disorder has an onset prior to age 18 (Early Onset Psychosis, EOP; Arango et al. 2008). More recently, studies have focused on measures of cortical morphology. The single study in EOP so far has identified greater loss of cortical thickness (CTH) in patients with schizophrenia over time (van Haren et al. 2011), whereas to our knowledge, no so far study has examined measures of surface area (SA) in EOP following a longitudinal design. We set out to examine measures of both CTH and SA in a sample of EOP at 10-year-follow-up.MethodsPatients with EOP were recruited at first episode, matched by sex and age with healthy controls (HC) and re-assessed at 10 years. Subjects were evaluated clinically and structural T1 volumes were acquired using magnetic resonance imaging at baseline and 10-year-follow-up. Images were preprocessed, segmented and analysed with FreeSurfer. Quality control procedure was carried out by two raters. Images were segmented and CTH and SA values were extracted for each parcellation employing Desikan-Killiany Atlas; these were grouped in frontal, occipital, temporal, parietal and cingulate lobes so as to reduce multiple comparisons. When group or group by time effects were detected, parcellations were individually examined. A linear mixed model was built using Stata IC 13.1 to evaluate the effect of group and time on CTH and SA, including hemisphere as fixed effects and correcting by total intracranial volume and setting a critical p-value of .05.ResultsThirty-nine subjects completed the follow-up. After removing 9 due to poor quality T1 images (technical problems, excess of movement), 28 subjects were finally included (13 EOP, 15 HC). There were no significant differences in age (EOP=26.9 ± 0.6 vs HC=27.2 ± 0.3 at follow-up) or sex distribution (%female: EOP=43% vs HC=38%) between groups. The distribution of diagnosis in the case group was: schizoaffective disorder (n=5), bipolar disorder with psychotic features (n=3), schizophrenia (n=2) and others (n=3).There was a trend-level group effect in global CTH (p = .07) which was significant in the frontal lobe (p = .014). EOP exhibited less CTH in the caudal middle frontal (p = .016) and pars opercularis (p = .03) and orbitalis (p = .007) of the inferior frontal gyrus. There was an effect of time in the parietal (p = .013) and occipital (p = .004) lobes consisting of thinner CTH at follow-up in both groups.There were no differences in SA between groups. Both showed an increase in total SA (p < .001) and for parietal (p < .001), temporal (p = .009) and occipital (p = .003) regions at follow-up. There a group by time effect in frontal SA, consisting of an increase over time in HC and a decrease in EOP (p = .044), specifically in medial orbito-frontal cortex (p = .039).DiscussionOur results have identified: 1) thinner cortices in frontal regions in EOP compared to HC, which seems to be constant over time; and 2) a decreased in SA in frontal areas in EOP along time, contrasting with HC, whose frontal surface increased at follow-up. These findings are consistent with another study (Greenstein et al. 2006) which also reported reduced CTH in frontal areas in EOP during development, while we found no abnormalities in temporal regions (Vita et al. 2012). Despite the small sample size, to our knowledge this is the longest follow-up of an EOP sample employing magnetic resonance imaging so far.

What can Cortical Development in Attention-Deficit/Hyperactivity Disorder Teach us About the Early Developmental Mechanisms Involved?

Studies of Attention-Deficit/Hyperactivity Disorder (ADHD) have shown developmental changes in the cortical mantle. Different dimensions of cortical morphology, such as surface area and thickness, relate to different neurodevelopmental mechanisms. As such, studying multiple dimensions may inform us about the developmental origins of ADHD. Furthermore, results from existing longitudinal samples await replication. Therefore, we conducted a longitudinal study of multiple cortical dimensions in a sizable, independent ADHD sample. We analyzed 297 anatomical MRI scans from two matched groups of 94 subjects with ADHD and 94 controls, aged 6-28 years. We estimated the developmental trajectories of cortical volume, surface, thickness and gyrification for 68 regions using mixed-effects regression analysis. Subjects with ADHD had smaller overall cortical volume, predominantly driven by decreases in frontal lobe volume that were associated with reduced surface area and gyrification. Nearly all decreases were stable across development. Only a few decreases survived stringent Bonferroni correction for multiple comparisons, with the smallest detectable Cohen's d |0.43|. There were no between-group differences in cortical thickness, or in subcortical volumes. Our results suggest that ADHD is associated with developmentally persistent reductions in frontal cortical volume, surface area, and gyrification. This may implicate early neurodevelopmental mechanisms regulating cortical expansion and convolution in ADHD.

Estimating the projected frontal surface area of cyclists from images using a variational framework and statistical shape and appearance models

We present a computer vision-based approach to estimating the projected frontal surface area (pFSA) of cyclists from unconstrained images. Wind tunnel studies show a reduction in cyclists’ aerodynamic drag through manipulation of the cyclist’s pose. Whilst the mechanism by which reduction is achieved remains unknown, it is widely accepted in the literature that the drag is proportional to the cyclist’s pFSA. This paper describes a repeatable automatic method for pFSA estimation for the study of its relationship with aerodynamic drag in cyclists. The proposed approach is based on finding object boundaries in images. An initialised curve dynamically evolves in the image to minimise an energy function designed to force the curve to gravitate towards image features. To overcome occlusions and pose variation, we use a statistical cyclist shape and appearance models as priors to encourage the evolving curve to arrive at the desired solution. Contour initialisation is achieved using a discriminative object detection method based on offline supervised learning that yields a cyclist classifier. Once an instance of a cyclist is detected in an image and segmented, the pFSA is calculated from the area of the final curve. Applied to two challenging datasets of cyclist images, for cyclist detection our method achieves precision scores of 1.0 and 0.96 and recall scores of 0.68 and 0.83 on the wind tunnel and cyclists-in-natura datasets, respectively. For cyclist segmentation, it achieves 0.88 and 0.92 scores for the mean dice similarity coefficient metric on the two datasets, respectively. We discuss the performance of our method under occlusion, orientation, and pose conditions. Our method successfully estimates pFSA of cyclists and opens new vistas for exploration of the relationship between pFSA and aerodynamic drag.

Predicting the Sprint Performance of Adolescent Track Cyclists Using the 3-Minute All-out Test.

Waldron, M, Gray, A, Furlan, N, and Murphy, A. Predicting the sprint performance of adolescent track cyclists using the 3-minute all-out test. J Strength Cond Res 30(8): 2299-2306, 2016-This study aimed to predict 500-m time trial (TT) and 2,000-m pursuit speed of adolescent cyclists (age range = 13-15 years) using mechanical parameters derived from a critical power (CP) test and anthropometric variables. Ten well-trained competitive cyclists were assessed for body composition, body mass, stature, and frontal surface area (FSA), as well as completing the CP test. The personal best speed (km·h) of each rider during competition in 500-m TT and 2,000-m pursuit races was predicted based on the CP test data and anthropometric profiles using multiple regression analysis. A combination of the CP·FSA and internal (predicted) to external work ratio performed by the cyclists (Wint:Wext) predicted 500-m TT speed (R = 0.97; standard error of the estimate (SEE) = 0.82, P ≤ 0.001), whereas a combination of mean power·FSA (mean power) and body fat percentage predicted 2,000-m pursuit speed (R = 0.90; SEE = 1.5, p < 0.001). Between 90 and 97% of the variance in the sprint performance of adolescent cyclists can be explained by mechanical and anthropometric parameters, derived from a single visit to the laboratory. The tests and equations provided can be adopted by coaches to predict performance and set appropriate training intensities.

The effects of forward rotation of posture on computer-simulated 4-km track cycling: Implications of Union Cycliste Internationale rule 1.3.013.

The aim of this research was to indicate improvements in 4-km cycling performance that may be gained as a function of reduced frontal surface area ( A) when Union Cycliste Internationale rule 1.3.013 is contravened. In 10 male cyclists age 26 ± 2 (mean ± standard deviation) years, height 180 ± 5 cm and body mass 71 ± 6 kg, entire cycling posture was rotated forward from where the nose of the saddle was 6 cm rearward of the bottom bracket spindle (P6) to 4, 2 and 0 cm (P4, P2 and P0); contravening Union Cycliste Internationale rule 1.3.013. Using computerised planimetry, A was estimated and a forward integration model was compiled to simulate 4-km track cycling end time ( T4km) when a fixed power profile was applied. At P2, there was a significant but non-meaningful reduction compared to P6 ( p &lt; 0.05, d &lt; 0.02). There were small but significant reductions in A and T4km between P6 and P0; −0.007 ± 0.004 m2 and −1.40 ± 0.73 s, respectively ( p &lt; 0.001, d = −0.259). There were no significant differences between P4 and P6 for A and T4km. These results suggest that at the most forward position (P0), a small but significant increase in 4-km performance can be expected compared to the legal position (P6). Moreover, the mean difference in T4km between P6 and P0 is greater than the winning margin at the Union Cycliste Internationale 4-km pursuit world championships four times in the previous 10 years.

Algorithm for Gesture Recognition Using an IR-UWB Radar Sensor

This paper introduces a human gesture recognition algorithm using an impulse radio ultra-wide- band (IR-UWB) radar sensor. Human gesture recognition has been one of the hottest research topics for quite a long time. Many gesture recognition algorithms or systems using other sensors have been proposed such as using cameras, RFID tags and so on. Among which gesture recognition systems using cameras have been extensively studied in past years and widely used in practical. While it might show some deficiencies in some cases. For example, the users might not like to be filmed by cameras considering their privacies. Besides, it might not work well in very dark environments. While RFID tags could be inconvenient to many people and are likely to be lost. Our gesture recognition algorithm uses IR-UWB radar sensor which has pretty high resolution in ranging and adjustable gesture recognition range, meanwhile, does not have problems in privacy issues or darkness. In this paper, the gesture recognition algorithm is based on the moving direction and distance change of the human hand and the change of the frontal surface area of hand towards radar sensor. By combining these changes while doing gestures, the algorithm may recognize basically 6 kinds of hand gestures. The experimental results show that these gestures are of quite good performance. The performance analysis from experiments is also given.

A longitudinal study: changes in cortical thickness and surface area during pubertal maturation.

Sex hormones have been shown to contribute to the organization and function of the brain during puberty and adolescence. Moreover, it has been suggested that distinct hormone changes in girls versus boys may contribute to the emergence of sex differences in internalizing and externalizing behavior during adolescence. In the current longitudinal study, the influence of within-subject changes in puberty (physical and hormonal) on cortical thickness and surface area was examined across a 2-year span, while controlling for age. Greater increases in Tanner Stage predicted less superior frontal thinning and decreases in precuneus surface area in both sexes. Significant Tanner Stage and sex interactions were also seen, with less right superior temporal thinning in girls but not boys, as well as greater decreases in the right bank of the superior temporal sulcus surface area in boys compared to girls. In addition, within-subject changes in testosterone over the 2-year follow-up period were found to relate to decreases in middle superior frontal surface area in boys, but increases in surface area in girls. Lastly, larger increases in estradiol in girls predicted greater middle temporal lobe thinning. These results show that within-subject physical and hormonal markers of puberty relate to region and sex-specific changes in cortical development across adolescence.

Relationships Between Propulsion and Anthropometry in Paralympic Swimmers

To characterize relationships between propulsion, anthropometry, and performance in Paralympic swimming. A cross-sectional study of swimmers (13 male, 15 female) age 20.5 ± 4.4 y was conducted. Subject locomotor categorizations were no physical disability (n = 8, classes S13-S14) and low-severity (n = 11, classes S9-S10) or midseverity disability (n = 9, classes S6-S8). Full anthropometric profiles estimated muscle mass and body fat, a bilateral swim-bench ergometer quantified upper-body power production, and 100-m time trials quantified swimming performance. Correlations between ergometer mean power and swimming performance increased with degree of physical disability (low-severity male r = .65, ± 0.56, and female r = .68, ± 0.64; midseverity, r = .87, ± 0.41, and r = .79, ± 0.75). The female midseverity group showed nearperfect (positive) relationships for taller swimmers' (with a greater muscle mass and longer arm span) swimming faster, while for female no- and low-severity-disability groups, greater muscle mass was associated with slower velocity (r = .78, ± 0.43, and r = .65, ± 0.66). This was supported with lighter females (with less frontal surface area) in the low-severity group being faster (r = .94, ± 0.24). In a gender contrast, low-severity males with less muscle mass (r = -.64, ± 0.56), high skinfolds (r = .78, ± 0.43), a longer arm span (r = .58, ± 0.60) or smaller frontal surface area (r = -.93, ± 0.19) were detrimental to swimming-velocity production. Low-severity male and midseverity female Paralympic swimmers should be encouraged to develop muscle mass and upper-body power to enhance swimming performance. The generalized anthropometric measures appear to be a secondary consideration for coaches.