Free Recall Memory Research Articles

Can warnings decrease the misinformation effect in post‐event debriefing?

Purpose – Operational debriefing and psychological debriefing both involve groups of participants (typically from the emergency services) discussing a critical incident. Research on post‐incident debriefing has previously raised concerns over the likelihood that this discussion may affect not only psychological responses, but also memory integrity. It is possible that discussion in this setting could increase susceptibility to the misinformation effect. This paper seeks to address these issues.Design/methodology/approach – The aim of this study was to investigate whether including a warning to the debriefing instructions about the possibility of memory contamination could reduce the misinformation effect. Participants viewed a stressful film, and were assigned to one of three conditions: debriefing with standard instructions, debriefing with a memory warning, or an individual recall control condition. Free recall memory and distress for the film were assessed.Findings – Results indicate that participants ...

Brain Volumetric Correlates of Memory in Early Parkinson's Disease

Free recall memory deficits are common in Parkinson's disease (PD), even at early stages before mild cognitive impairment or dementia. Their association with brain structural changes has not been established. We studied local gray matter volumes in relation to different memory tasks in early stage PD. Magnetic resonance images (MRI) and neuropsychological data were obtained from 28 non-demented, medicated PD patients, and 28 healthy controls. The gray matter segments of T1-weighted MRI images were analyzed using voxel-based morphometry in relation to visual and verbal memory tasks. Measures of immediate free recall, verbal learning, delayed recall and memory consolidation were obtained. A novel measure of incidental memory was included. Patients and controls showed no significant group differences in local gray matter volumes. Voxel-based morphometry analyses revealed that worse performance on an incidental visual memory task was associated with smaller right parietal gray matter volume (Family-wise error corrected P = 0.002). This association was present in the PD group (corrected P = 0.005), but not in controls (corrected P > 0.99). No associations between gray matter volumes and the other memory tasks were found in either group. The results suggest that right parietal cortical gray matter volume is related to free recall memory deficits in early stage PD in conditions not involving an intention to memorize visual items. This preliminary finding needs to be established in further studies utilizing incidental memory tasks in PD.

Does source memory impairment associated with emotionally arousing stimuli occur at encoding or retrieval?

The present experiment investigated whether negatively arousing stimuli produce source memory impairment and whether the impairment occurs at encoding or retrieval. Participants were presented with negatively arousing, positively arousing, and neutral pictures. Each picture was followed by an instructional slide that indicated whether the picture was an Apple-kind or an Orange-kind. Item memory was assessed by free recall and source memory was assessed by asking participants to classify the recalled pictures into the two kinds of pictures. The results indicated that item memory was greater for the negatively arousing pictures than for the positively arousing and the neutral pictures. However, the negatively arousing pictures produced more misattribution errors than the neutral pictures, replicating source memory impairment. It was concluded that source memory impairment associated with negatively arousing stimuli occurs at encoding.

L’influence de la valence émotionnelle positive des mots sur la mémoire des enfants

The two experiments reported here examine the influence of the emotional positive valence of words on both free recall (Experiment 1) and recognition memory performance (Experiment 2) in 7- and 9-year-old children. In these experiments, we observed a facilitation effect for positive words on children memory at both 7 and 9. This facilitation effect was found in both memory tasks. These findings add new evidence to the experimental study of the influence of emotion on children memory and are discussed in relation to current semantic explanations of the emotional enhancement of memory.

Older Adults' Memory for Verbally Presented Medical Information

Previous research demonstrates that patients typically have difficulty remembering information presented during healthcare consultations. This study examined how older adults learn and remember verbally presented medical information. Healthy older adults were tested for recall in experimental and field settings. Participants viewed a five-minute video of a simulated healthcare consultation and completed free recall, cued recall, and recognition memory tasks. Differences in performance were observed between older and younger adults in the experimental condition on all memory tasks and in the field condition on the cued recall task; older adults tended to remember less information than younger adults. Though older adults had difficulty spontaneously recalling medical information, they were able to take advantage of cues to access verbally learned information. Findings of this study highlight the importance of developing and implementing measures to maximize the abilities of older adults to learn and remember important medical information communicated by healthcare providers.

The Cognitive-Enhancing Effects of Bacopa monnieri: A Systematic Review of Randomized, Controlled Human Clinical Trials

Traditional knowledge suggests that Bacopa monnieri enhances cognitive performance. Such traditional beliefs have now been scientifically tested through a handful of randomized, controlled human clinical trials. The current systematic review aimed to examine the scientific evidence as to whether Bacopa can enhance cognitive performance in humans. A systematic review of randomized controlled trials is presented. Multiple databases were systematically searched by multiple authors. Relevant trials were objectively assessed for methodological quality. The subjects studied were adult humans without dementia or significant cognitive impairment. B. monnieri, including Bacopa extracts, were administered over long-term supplementation periods. Any validated cognitive test, whether a primary or secondary outcome. Six (6) studies met the final inclusion criteria and were included in review. Trials were all conducted over 12 weeks. Across trials, three different Bacopa extracts were used at dosages of 300-450 mg extract per day. All reviewed trials examined the effects of Bacopa on memory, while other cognitive domains were less well studied. There were no cognitive tests in the areas of auditory perceptual abilities or idea production and only a paucity of research in the domains of reasoning, number facility, and language behavior. Across studies, Bacopa improved performance on 9 of 17 tests in the domain of memory free recall. There was little evidence of enhancement in any other cognitive domains. There is some evidence to suggest that Bacopa improves memory free recall with evidence for enhancement in other cognitive abilities currently lacking perhaps due to inconsistent measures employed by studies across these cognitive domains. Research into the nootropic effects of Bacopa is in its infancy, with research still yet to investigate the effects of Bacopa across all human cognitive abilities. Similarly, future research should examine the nootropic effects of Bacopa at varied dosages and across different extracts.

S2‐01‐01: Neuropsychological assessment of dementia on Guam

Parkinson-Dementia Complex (PDC) is a neurodegenerative disorder that occurs almost exclusively in the indigenous Chamorro population on the Marianas island of Guam. Parkinsonism typically occurs concomitantly with the onset of dementia and is essentially identical to that of idiopathic Parkinson's disease (PD). PDC is a tauopathy characterized by neurofibrillary tangles and neuron loss in a number of brainstem nuclei, limbic structures, and association cortices. There is little deposition of amyloid and alpha-synuclein pathology is rare. A pure dementia syndrome without significant motor abnormality is also quite prevalent in Guam's elderly Chamorro population. Little is known about the underlying neuropathology of this late-life Guam dementia (GD), but it has been variably associated with Alzheimer's disease (AD) or PDC pathology in a handful of cases. The dementia syndromes of PDC and GD have not been carefully characterized, but clinical reports suggest that they usually begin with forgetfulness, disorientation, and difficulty with problem solving and calculations. A battery of culturally-adapted neuropsychological tests was administered to Chamorro patients with clinically-diagnosed PDC (n = 37) or GD (n = 55), and to healthy Chamorro elderly control (EC) subjects (n = 45). The tests were chosen to be sensitive to cognitive changes associated with PD or AD, and included measures of memory, attention, language, executive function, visuospatial ability, and psychomotor speed. Patients with PDC and GD were impaired relative to EC subjects on all neuropsychological tests and exhibited similar profiles of deficits that included frank amnesia (i.e., poor learning, abnormally rapid forgetting, impaired free recall and recognition memory), mild aphasia (i.e., anomia, verbal fluency impairment), executive dysfunction, and constructional apraxia. This qualitative pattern of deficits resembles that of the cortico-limbic dementia syndrome of AD. However, some features of fronto-striatal dysfunction were also evident (i.e., set shifting deficits, equally poor semantic and letter fluency), even in those without Parkinsonism. The striking similarities in the cognitive profiles associated with PDC and GD suggest that the two conditions may reflect different points along a spectrum of a single disease in the Chamorro population. The dementia syndrome appears largely cortico-limbic in nature and may reflect the tauopathy common to both disorders.

The Effect of Encoding Condition on Free Recall in Parkinson's Disease: Incidental and Intentional Memory are Equally Affected

Free recall memory deficits are common at early stages of Parkinson's disease (PD). As most studies have used intentional memory tasks, there is little information on how non-intentional, incidental encoding conditions affect memory performance in PD. We studied possible differences between PD patients and controls on free recall using incidental and intentional visual memory tasks. Free recall was examined in relation to attentive/executive functioning and subjective memory complaints. A total of 29 non-demented, medicated PD patients (age 60, disease duration 19 months) and 29 healthy controls (age 61) participated in the study. Incidental free recall was studied using a memory-modification of the Boston naming test (Memo-BNT) and intentional free recall with the 20 Objects test. There was a significant main effect for group due to worse free recall performances in the PD group. No statistically significant interaction between group and encoding condition was observed. The free recall deficit in the PD group was related to cognitive/psychomotor slowing, but not to attentive/executive task demands, or to subjective memory complaints. The results indicate that PD patients are impaired on free recall irrespective of encoding condition.

The Effects of Multivitamins on Cognitive Performance: A Systematic Review and Meta-Analysis

Complementary medicine use is becoming increasingly popular with multivitamins being the most commonly used vitamin supplement. Although adequate vitamin and nutrient concentrations are necessary for optimal health and cognitive functioning, there is no scientific consensus as to whether multivitamin use prevents cognitive decline or improves mental functioning. The aim of the present study was to determine if multivitamins can be used efficaciously to improve cognitive abilities. A systematic review of randomized controlled trials was performed. Meta-analysis was performed on those cognitive tests used across the largest number of studies. Multiple electronic databases were searched until July 2011 by two authors. Randomized, placebo-controlled trials were considered appropriate if they reported on the chronic effects (≥1 month) of oral multivitamin supplementation on any valid cognitive outcomes. Ten trials were included in review (n = 3,200). Meta-analysis indicated that multivitamins were effective in improving immediate free recall memory (SMD = 0.32; 95% CI: 0.09-0.56, p < 0.01) but not delayed free recall memory (SMD = -0.14; 95% CI: -0.43-0.14, p = 0.33) or verbal fluency (SMD = 0.06; 95% CI: -0.05-0.18, p = 0.26). There was no evidence of publication bias or heterogeneity. Other cognitive abilities sensitive to AD pathology, such as executive and visuospatial functions, were found to be under researched. In conclusion, multivitamins were found to enhance immediate free recall memory but no other cognitive domains.

The contribution of executive functions deficits to impaired episodic memory in individuals with alcoholism

Individuals with alcoholism commonly exhibit impaired performance on episodic memory tasks. However, the contribution of their impaired executive functioning to poor episodic memory remains to be clarified. Thirty-six recently detoxified and sober asymptomatic alcoholic men and 36 matched non-alcoholic participants were tested for processing speed, prepotent response inhibition, mental flexibility, coordination of dual-task and a verbal episodic memory task. Compared with non-alcoholic individuals, the alcoholic patients showed impaired executive functions combined with below normal performance on both free and delayed recall. In contrast, processing speed, cued recall and recognition were preserved. Regression analyses revealed that 47% of alcoholics' episodic memory's free recall performance was predicted by mental flexibility and that 49% of their delayed recall performance was predicted by mental flexibility, manipulation of dual-task and prepotent response inhibition. Regarding participants' executive predictors of episodic memory performance, the slopes of β coefficients were significantly different between the two groups, with alcoholics requiring more their executive system than non-alcoholics. Once detoxified, alcoholic patients showed episodic memory deficits mainly characterized by impaired effortful (executive) processes. Compared with controls, patients used effortful learning strategies, which are nonetheless less efficient.

Differing emotional sensitivities in the two factors of personal need for structure

The current project examines dispositional orientations toward positive or negative stimuli based on individual differences in personal need for structure (PNS). Although Neuberg and Newsom (1993) describe PNS as stemming from two sources of simple structure, desire for structure (DFS) and response to lack of structure (RLS), the two subscales are commonly combined. The current study found that high DFS (but not high RLS) was associated with a tendency to create more positive words in a word-fragment-completion task, generate more positive content in a story-completion task, and remember more positive words in a free-recall memory task. High-RLS (but not high-DFS) was associated with the opposite tendency (i.e., oriented toward negatives). Possible revisions to previous conclusions involving PNS are discussed.

Progesterone at encoding predicts subsequent emotional memory

Significant sex differences in the well-documented relationship between stress hormones and memory have emerged in recent studies. The potentiating effects of glucocorticoids on memory vary across the menstrual cycle, suggesting a potential interaction between these stress hormones and endogenously cycling sex hormones. Here, we show that memory for emotional materials changes significantly in accordance with hormonal changes across the menstrual cycle, suggesting that ovarian sex hormones influence the modulation of emotional memories. Sixty healthy, naturally cycling women rated 120 images on arousal and valence. One week later they completed free recall and recognition memory tests. Their menstrual cycle phases were estimated by self-report and confirmed by salivary assay of 17β-estradiol and progesterone. Memory for emotional items only was significantly better in the high hormone (luteal) phase compared with the low hormone (follicular) phase on the free recall test; on both tests memory correlated positively with progesterone collected at the time of encoding. These findings suggest that emotional memory performance changes across the menstrual cycle, and that this change is in part mediated by endogenous progesterone cycling.

L’imagerie bizarre et la mémoire

One experiment examined free recall memory performance for bizarre and common pictures. Bizarre pictures were designed either deleting some components (SB pictures) either adding some components (AB pictures). A classical bizarreness effect was only obtained for AB pictures. Indeed no facilitative effect of bizarreness was obtained when incomplete fragmented pictures were used. Results were discussed in light of theories interested by the explanation of the bizarreness effect in memory.

Memory functioning in children and adolescents with autism.

Memory functioning in children and adolescents ages 5-19 with autism (n = 50) and typically developing controls (n = 36) was assessed using a clinical assessment battery, the Test of Memory and Learning (TOMAL). Participant groups were statistically comparable in age, nonverbal IQ, handedness, and head circumference, and were administered the TOMAL. Test performance on the TOMAL demonstrated broad differences in memory functioning in the autism group, across multiple task formats, including verbal and nonverbal, immediate and delayed, attention and concentration, sequential recall, free recall, associative recall, and multiple-trial learning memory. All index and nearly all subtest differences remained significant even after comparing a subset of the autism group (n = 36) and controls that were matched for verbal IQ (p > .05). However, retention of previously remembered information after a delay was similar in autism and controls. These findings indicate that performance on measures of episodic memory is broadly reduced in autism, and support the conclusion that information encoding and organization, possibly due to inefficient cognitive processing strategies, rather than storage and retrieval, are the primary factors that limit memory performance in autism.

Accounting for immediate emotional memory enhancement

Memory for emotional events is usually very good even when tested shortly after study, before it is altered by the influence of emotional arousal on consolidation. Immediate emotion-enhanced memory may stem from the influence of emotion on cognitive processes at encoding and retrieval. Our goal was to test which cognitive factors are necessary and sufficient to account for EEM, with a specific focus on clarifying the contribution of attention to this effect. In two experiments, participants encoded negative-arousing and neutral pictures. In Experiment 1, under divided-attention conditions, negative pictures were better attended and recalled even when they were matched with neutral pictures on semantic relatedness and distinctiveness, and attention at encoding predicted subsequent emotion-enhanced memory. The memory advantage for emotional stimuli was only abolished when attention to emotional and neutral stimuli was also matched, under full-attention in Experiment 1 and under divided-attention in Experiment 2. Emotional memory enhancement was larger in Experiment 1 when the control of organization and distinctiveness was relaxed. These findings suggest that attention, organization and distinctiveness provide a necessary and sufficient account for immediate emotion-enhanced free recall memory.

Population-based case–control study of cognitive function in early Parkinson's disease (NEDICES)

BackgroundPopulation-based assessments of cognitive function in patients with early Parkinson's disease (PD) are rare. We examined whether patients with early PD have cognitive deficits when compared with matched controls MethodsAll participants were age 65years or older (median=76years) and were enrolled in the Neurological Disorders in Central Spain (NEDICES) study in central Spain. We identified all participants with early PD (<5years duration) (N=46). These were matched to 138 controls. Neuropsychological test scores were compared in PD patients vs. controls. In logistic regression models, we adjusted for the effects of confounding variables. In these models, the dependent variable was the neuropsychological test score (lowest quartile vs. all other quartiles) and the independent variable was PD vs. control. ResultsSixteen of 46 patients (34.8%) with early PD were previously undiagnosed. Subjective memory complaint was present in 27 (58.7%) PD patients vs. 51 (37.0%) controls (p=0.010). In logistic regression models that adjusted for gender, education, and depressive symptoms or antidepressant use, PD patients performed less well on the 37-item version of the Mini-Mental State Examination (p=0.04), animal (p<0.001) and fruit fluency (p=0.04) as well as in a delayed free recall memory test (p=0.04) than controls. ConclusionsIn this population-based sample of older patients with early PD, the rate of subjective and object cognitive impairment was appreciable. Patients with PD of less than five years duration performed relatively poorly on tests of global cognition, verbal fluency and memory. Clinicians should be vigilant to these cognitive difficulties even in the early stages of PD.

Sex differences in latent cognitive abilities ages 5 to 17: Evidence from the Differential Ability Scales—Second Edition

Sex differences in the latent general and broad cognitive abilities underlying the Differential Ability Scales, Second Edition were investigated for children and youth ages 5 through 17. Multi-group mean and covariance structural equation modeling was used to investigate sex differences in latent cognitive abilities as well as changes in these differences across age. Most broad abilities showed mean differences across the sexes, and all such differences varied across ages. Girls showed an advantage on the processing speed (Gs) first-order residual factor. Girls also showed advantages at some ages on free-recall memory, a narrow ability of long term retrieval (Glr). Boys showed a developmentally-related advantage on a visual–spatial ability (Gv) first-order residual factor, depending on age. Younger girls showed an advantage on short-term memory (Gsm). No statistically significant sex differences were shown on the latent comprehension-knowledge (Gc) factor, or on a second-order, latent g factor. Boys showed larger variances for several broad abilities, some substantial, but those differences were not statistically significant.

The nature of episodic memory deficits in MCI with and without vascular burden

This study measured episodic memory deficits in individuals with mild cognitive impairment (MCI) as a function of their vascular burden. Vascular burden was determined clinically by computing the number of vascular risk factors and diseases and neuroradiologically by assessing the presence and severity of white matter lesions (WML). Strategic memory processes were measured with free recall and temporal contextual memory tasks requiring self-initiated retrieval. Nonstrategic memory retrieval processes were appraised with a five-choice recognition procedure. Results showed that MCI participants with high vascular burden displayed impairment of strategic memory processes, whereas MCI participants with no vascular burden showed impairment of both strategic and nonstrategic memory processes. A similar pattern was found whether vascular burden was measured using a clinical index of vascular risk profile or whether it was measured neuroradiologically by assessing the extent and severity of subcortical WML. However, the effect of WML on memory differed as function of level of education, used here as a proxy for cognitive reserve. Among participants with MCI, those who had higher education and no WML were the least memory impaired. The study also examined memory as a function of whether patients later progressed to dementia after a three-year follow-up. When examining progressors’ performance, strategic and nonstrategic processes were both impaired in progressors with no concomitant vascular conditions, whereas progressors with a high vascular burden showed less impairment of nonstrategic than strategic processes. Overall, results indicate that the presence of vascular burden in MCI is associated with selective impairment of strategic memory processes.

Long Term Memory Profile of Disorders Associated with Dysregulation of the RAS-MAPK Signaling Cascade

In the present study we evaluated long term memory in twenty individuals with molecularly confirmed diagnosis of Noonan syndrome and LEOPARD syndrome, two disorders caused by mutations in genes coding transducers participating in the RAS-MAPK signaling cascade. The profile of explicit long term memory abilities was investigated using PROMEA, which includes a battery of tests specifically developed to assess memory and learning in verbal, visual and spatial domains. Ten individuals (50%) had impaired (≤5th percentile) or below average (≤15th percentile) performance on a delayed verbal free recall memory task, four (20%) on a delayed visual recognition memory task, and only one (5%) on a delayed spatial recognition memory task. Our data suggest that dysregulation of the RAS-MAPK cascade may be associated with a pattern of reduced verbal recall memory performance but relative sparing of visual and spatial recognition memory.

Multistrategic Memory Training with the Metamemory Concept in Healthy Older Adults

ObjectiveAccording to the increase of older people, the need for effective methods to maintain or improve cognitive functions in the elderly has increased. These cognitive enhancing methods may contribute to the prevention of elderly cognitive decline by aging and dementing illness as well. This study aimed to examine the effectiveness of multistrategic memory training with the metamemory concept on cognitive functions in the normal health elderly in Korea.MethodsThe program used in this study was developed by psychiatrists and psychologists in accordance with Korean situations. We applied the training program to the community-dwelling elderly with subjective memory complaints. Twenty participants were randomly received the intervention with 20 non-treatment controls. This program consisted of 10 sessions and was administered once a week. We examined the effects of this memory training for verbal memory, visuospatial memory, working memory, and verbal fluency ability by repeated ANOVA.ResultsThere were significant improvements in Word List Short-term Delayed Free and Cued Recall, Word list Long-term Delayed Free and Cued Recall and visuospatial recognition memory. Performance improvements in visuospatial span forwards and the Categorical Fluency Test were also significant. These improvements were still significant after adjusting for depression improvement exact categorical fluency.ConclusionThis study shows that multistrategic memory training with the metamemory concept may improve memory ability and other cognitive functions which are not trained and that these improvements may be achieved by pure cognitive training effects.