The business sector in Lampung Province is the foundation for improving the regional and regional economy. Associated with increasing the added value of superior products, it is necessary to do a mapping of the leading sectors in Lampung Province using input-output analysis. Thus, the purpose of this study is to find out which business sector is a key sector for accelerating development in Lampung Province in 2018, using the 2010 input-output analysis method by updating data on the basis of 2018 producer prices by classifying 34 Field Sectors. Business. The results of this study are presented by making a typology (interaction) between the backward linkage coefficient, and the forward linkage coefficient of the production sector as a whole, so that the sector becomes the main priority in order to accelerate development in Lampung Province based on indirect linkages. namely the Horticultural Crops Sector; and the Highway Transportation sector; and key sectors based on direct linkages, namely: Horticultural Crops; Processing industry; Electricity; and Highway Transportation.