Purpose: This research aimed to evaluate the effect of treatment with Forsus Fatigue Resistant Device (FFRD) and traditional Class III elastics in treating class III malocclusion. Patients and Methods: The present study was applied to twenty female patients divided into two groups equally and randomly with age ranged from 14 to 16 years old, Group I treated with inverted FFRD which was attached to the mandibular first molar extra-oral tube and distal to the bracket of the maxillary canine and conventional class III elastics used in Group II. Results: Significant increase revealed in ANB angle in both groups while, there was significant decrease in S-A distance in FFRD group while, in relation to vertical skeletal measurement SN to mandibular plane angle (SN-MP) there was significant decrease in FFRD group and significant increase in intermaxillary elastic group. There was also significant proclination in maxillary anterior teeth and significant retroclination of the mandibular one. Conclusions: In class III malocclusion the use of inverted FFRD and elastics is successful treatment method to improve the maxilla-mandibular relationship by improving anteroposterior relationship (ANB angle). The FFRD is suggested in uncooperative patients as it did not require patient cooperation as class III elastics.