Food Intake Status Research Articles

The effect of nutrition counseling on nutritional status for breast cancer patients in dr. Sardjito Hospital, Indonesia

Background: Nutrition counseling in breast cancer (BC) patients show long-term adherence to a dietary pattern and effects on nutritional status and quality of life (QOL).Objective : We evaluated the effects of nutrition counseling for nutrients intake dan nutritional status improvement among breast cancer patients.Material and Methods: This research was conducted in a Pre-experimental design; one group pretest-postest design was conducted on 45 BC patients who underwent radiotherapy for five weeks in the Radiotherapy Unit, dr. Sardjito Hospital, Indonesia. Nutrition counseling was demonstrated by trained fieldworkers to 45 participants using a nutrition booklet for BC patients and a food model as an intervention technique. Continuous nutrition counseling was given three times: weeks 1, 3, and 5 of radiotherapy. We examined anthropometry, biochemical, physical, dietary, and Patient-Generated Subjective Global Assessment (PG-SGA) questionnaire to obtain nutritional status.Results: Most of the participants had a body mass index (BMI) ≥25 kg/m2 (62.2%). After the participants were receiving nutrition counseling, there were increases in intake of energy, protein, carbohydrate, vitamin A, vitamin C, and vitamin E amounted 124.54 kcal, 8.12 g (p=0.01), 5.84 g, 234.43 mg, 0.042 mg, and 0.44 mg, respectively. Intake of fruits and vegetables improved on the first, third, and fifth week (1.44, 2.36, and 4.03 portion/day, respectively) (p=0.001). Handgrip strength (HGS) showed slight improvement (p=0.081). However, HGS ameliorated from 15.85 kgs in the early to 16.97 kgs in the end stage of therapy. Bodyweight decreased 0.28 kg; however, there are no changes in PG-SGA score, hemoglobin (Hb), and albumin levels.Conclusion: Nutrition counseling improves patients’ nutrition intake despite there is no significant alteration in nutritional status. In addition, nutrition counseling for breast cancer patients during radiotherapy is essential to maintain and improve nutrient intake and nutritional status. In the long-term period, it might be affected to improve quality of life.

Overview of Macro Nutrient Intake and Nutritional Status of Students at the Putri Hidayatullah Islamic Boarding School, Ternate City

Adolescents are one of the nutritionally vulnerable groups. At this time, adolescents enter the second phase of rapid growth and then physical growth declines as young adults enter. Problems that arise in adolescents are undernutrition and overnutrition. One that is related to nutritional status is nutrient intake which is very influential on a person's nutritional status. Nutrient intake is influenced by eating habits and eating patterns of adolescents themselves. The purpose of this study was to determine the description of macronutrient intake and nutritional status at the Putri Hidayatullah Islamic Boarding School, Ternate City. The type of research used is descriptive research. The sampling technique used total sampling with a total sample of 29 people. The tools used were Microtoise, Bathroom Scale and form food recall 24. The results showed that the intake of macronutrients, as many as 28 people (96.6%) with less energy intake, 29 people (100.0%) with less protein intake, 16 people (55.2%) with more fat intake and 26 people (89.7%) with less carbohydrate intake. There were 25 people (86.2%) with normal nutritional status. It was concluded that from the results of the respondents had less protein intake and most had less energy and carbohydrate intake. On the other hand, most of these teenagers have good fat intake with normal nutritional status.

Household Food Security, Nutritional Intake, and Nutritional Status of Pregnant Women in the Central Tapanuli Regency

BACKGROUND: Malnutrition that occurs during pregnancy can result in inadequate household food security so that it will affect the baby to be born. AIM: This study aims to determine household food security, nutrient intake, and nutritional status of pregnant women in the Central Tapanuli Regency. METHODS: This research is part of the DRPM research with the title of improving the nutrition of pregnant women and the success of breastfeeding immediately after birth through strengthening household food security in the Central Tapanuli Regency. The stages of this research are to identify the level of household food security and nutrient intake as well as the nutritional status of pregnant women. The study was conducted using observation and interviews as well as measuring LILA, examination of Hb levels, and iodine levels in the urine of 131 pregnant women purposively in eight districts of the Central Tapanuli. RESULTS: The household food security of status that is food insecure is 18.3%. The nutritional status of pregnant women with anemia was 58.7% and those with SEZ were 19.1% fiber with the low levels of iodine in the urine as much as 63.9%. Adequate intake of energy nutrients is 42% and sufficient protein is 38.9%. There was a significant relationship between food security status and energy intake (p = 0.000; OR = 53.9) and protein intake (p = 0.004; OR = 4.1). CONCLUSIONS: There is a significant relationship between household food security status with energy and protein intake of pregnant women. Increased consumption of foods containing animal protein is recommended for pregnant women related to household food insecurity.

Stomach secretes estrogen in response to the blood triglyceride levels

Mammals receive body energy information to maintain energy homeostasis. Ghrelin, insulin, leptin and vagal afferents transmit the status of fasting, blood glucose, body fat, and food intake, respectively. Estrogen also inhibits feeding behavior and lipogenesis, but increases body fat mass. However, how blood triglyceride levels are monitored and the physiological roles of estrogen from the perspective of lipid homeostasis remain unsettled. Here, we show that stomach secretes estrogen in response to the blood triglyceride levels. Estrogen-secreting gastric parietal cells predominantly use fatty acids as an energy source. Blood estrogen levels increase as blood triglyceride levels rise in a stomach-dependent manner. Estrogen levels in stomach tissues increase as blood triglyceride levels rise, and isolated gastric gland epithelium produces estrogen in a fatty acid-dependent manner. We therefore propose that stomach monitors and controls blood triglyceride levels using estrogen, which inhibits feeding behavior and lipogenesis, and promotes triglyceride uptake by adipocytes.

The Association between Daily Total Dietary Nutrient Intake and Recent Glycemic Control States of Non-Pregnant Adults 20+ Years Old from NHANES 1999-2018 (Except for 2003-2004).

Background: Although daily total dietary nutrient intakes were potentially important factors in maintaining glycemic balance, their overall effect on glycemic control was still unclear among American adults. Objectives: We aimed to examine the association between daily total dietary nutrient intake and recent glycemic control status (RGCS). Methods: This cohort was composed of 41,302 individuals from the National Health and Nutrition Examination Survey (NHANES). The daily total intake of dietary nutrients and RGCS were independent and dependent variables, respectively. To evaluate their association, we carried out binary logistic regression, model fitting, linear discriminant analysis, and the receiver operator characteristic (ROC) analysis. Results: The result of robust check model showed that only the daily total dietary vitamin B6 intake (adjusted OR = 0.848; 95% CI: 0.738, 0.973; p-value = 0.019) was significantly negatively correlated with RGCS. When daily total dietary vitamin B6 intake and glycosylated hemoglobin (HbA1c) were used as independent variables and dependent variables, respectively, to fit the curves and lines, the established robust check model could distinguish American adults with different RGCS well. Moreover, the robust check model results of ROC analysis indicated that daily total dietary vitamin B6 intake might be a potential predictor for RGCS (AUC = 0.977; 95% CI: 0.974, 0.980; p-value < 0.001). Conclusions: This study showed that only daily total dietary vitamin B6 intake was a beneficial factor in RGCS, but it might need further multicenter or prospective studies to verify whether vitamin B6 had biological implications and public health meaning for glycemic control among American adults (specifically referred to non-pregnant participants over 20 years old).

Home Food Environments of Mothers in South-Eastern Africa and California-An Illustration of Global Extremes

INTRODUCTION: The type and availability of food in the home is known to directly shape food intake and weight status, but cross-cultural differences remain poorly documented. &#x0D; &#x0D; OBJECTIVE: The purpose of this study was to describe and compare the home food environments of low-income, childbearing women living in a low-income country (Malawi) and a high-income country (United States).&amp;nbsp; &#x0D; &#x0D; METHODS: A home food environment survey was available in 714 mothers in Malawi (mean BMI 19.5, mean age 22.1 years) and 371 in California (mean BMI 31.8, mean age 28.1 years). &#x0D; &#x0D; RESULTS: Mothers in California vs. Malawi had on average (SD) 22.8 (4.4) vs. 1.2 (1.4) different food items in the home. The women in California had an abundance of fruits and vegetables that were virtually absent in the homes of Malawian women. The most prevalent food in the homes in Californian women was rice (in 97% homes) and in Malawian women was corn flour (in 47% of homes). &#x0D; &#x0D; CONCLUSIONS: Given the global extremes in food availability, efforts to address over and under food availabilities in the homes of childbearing women need to move beyond country centric approaches. It is time to consider maternal and child health as a global priority.

HUBUNGAN PENGETAHUAN GIZI, AKTIVITAS FISIK DAN ASUPAN ZAT GIZI DENGAN STATUS GIZI PADA REMAJA DI SMK KECAMATAN GRESIK

Background: Indonesia has three burdens of nutritional problems (triple burden), especially in adolescents, namely stunting, wasting and obesity as well as micronutrient deficiencies. East Java Province, the prevalence of obese adolescents aged 13-15 years is 13.3% and aged 16-18 years is 11.3%. Especially in Gresik Regency, the prevalence of thin adolescents aged 16-18 years is 9.41%, fat adolescents are 15.74% and obese adolescents are 7.47%. The problem of undernutrition and overnutrition, especially in adolescents can have a very bad impact on the sufferer. Objective: To analyze the level of nutritional knowledge, physical activity and nutrient intake with adolescents nutritional status of high school in Gresik District. Method: This research is a purposive sampling research with cluster sampling design. Respondents as many as 98. Data on respondent identity, knowledge of nutrition, physical activity and nutrient intake were taken through interviews with a questionnaire guide (Nutrition Knowledge, GPAQ and Recall). Antropometric data obtained through direct measurements. Statistical analysis was carried out bivariately with the Spearman Rank test ang multivariate with the Multiple Discriminant test. Result: The result of BMI/U are 73.5% good nutrition and 17.3% over nutrition. There is no relationship between nutritional knowledge and nutritional status (p value 0.323 &gt; 0.05), there is no relationship between physical activity and nutritional status (p value 0.772 &gt; 0.05), there is no relationship between nutrient intake and nutritional status (p value &gt; 0.05). There is no relationship between knowledge of nutrition, physical activity, nutrient intake and nutritional status because the sig. value in the multiple discriminant test is &gt; 0.05. Conclusions: There is no relationship between nutritional knowledge and nutritional status, there is no relationship between physical activity and nutritional status, there is no relationship between nutrient intake and nutritional status and there is no relationship between knowledge of nutrition, physical activity, nutrient intake and nutritional status.

ENERGY AND NUTRIENT INTAKE IN OSTOMY PATIENTS AND CORRELATIONS WITH ANTHROPOMETRIC VARIABLES: RESULTS FROM A REFERENCE HOSPITAL IN THE STATE OF PERNAMBUCO, BRAZIL.

Studies that assess the food intake and nutritional status of ostomy patients are scarce in the literature. However, such individuals have symptoms in the postoperative period that determine changes in the intake of calories and nutrients as well as anthropometric variables. Estimate the energy and nutrient intake of ostomy patients and determine correlations with anthropometric variables. A cross-sectional study was conducted with ostomy individuals in outpatient follow-up at a reference hospital for postoperative ostomy surgery in the city of Recife, Brazil. Demographic, socioeconomic, clinical, anthropometric, and dietary data were collected through interviews and from patient charts. Statistical analyses were performed with the aid of the Statistical Package for the Social Sciences, version 13.0 for Windows, with the level of significance set at 5% (P≤0.05). The sample was composed of 100 individuals (54% males) with a mean age of 55.1±15.4 years. Colostomy patients predominated (82%) and had a greater frequency of excess weight compared to ileostomy patients (86.36% versus 13.64%). Median intake was below the Estimated Average Requirements, especially for vitamins A, C, and E. Significant inverse correlations were found between carbohydrate intake and both arm circumference and triceps skinfold (P=0.0302 for each) and a positive correlation was found between protein intake and arm muscle circumference (P=0.0158) in male patients. The present study found significant correlations between macronutrient intake and anthropometric variables indicative of reserves of lean and adipose mass. Moreover, intake was below the recommended values according to sex and age group, especially with regards to vitamins.

Dietary Naringenin Preserves Insulin Sensitivity and Grip Strength and Attenuates Inflammation but Accelerates Weight Loss in a Mouse Model of Cancer Cachexia.

Cancer cachexia is characterized by the loss of skeletal muscle resulting in functional impairment, reduced quality of life and mortality. Naringenin, a flavonoid found in citrus fruits, improves insulin sensitivity and reduces inflammation and tumor growth in preclinical models. Therefore, the study hypothesizes that dietary supplementation of naringenin will improve insulin sensitivity, decrease inflammation, slow body weight loss, and delay tumor growth in a mouse model of cancer cachexia. Mice are fed 2 wt% dietary naringenin before and during initiation of cancer cachexia using inoculated adenocarcinoma-26 cells (C-26). Food intake, body weight, body composition, muscle function, insulin tolerance, and inflammatory status are assessed. Although naringenin-fed tumor-bearing mice exhibit reductions in body weight and food intake earlier than control diet-fed tumor-bearing mice, dietary naringenin is protective against loss of muscle strength, and attenuates the onset of insulin resistance and markers of inflammation. Dietary supplementation of naringenin improves multiple aspects of metabolic disturbance and inflammation during cancer cachexia progression in [C-26 tumor-bearing] mice. However, the acceleration of anorexia and weight loss is also observed. These findings emphasize the link between inflammation and insulin resistance as a basis for understanding their roles in the pathogenesis of cancer cachexia.

Decision-Making Processes Related to Perseveration Are Indirectly Associated With Weight Status in Children Through Laboratory-Assessed Energy Intake.

Decision-making contributes to what and how much we consume, and deficits in decision-making have been associated with increased weight status in children. Nevertheless, the relationships between cognitive and affective processes underlying decision-making (i.e., decision-making processes) and laboratory food intake are unclear. We used data from a four-session, within-subjects laboratory study to investigate the relationships between decision-making processes, food intake, and weight status in 70 children 7-to-11-years-old. Decision-making was assessed with the Hungry Donkey Task (HDT), a child-friendly task where children make selections with unknown reward outcomes. Food intake was measured with three paradigms: (1) a standard ad libitum meal, (2) an eating in the absence of hunger (EAH) protocol, and (3) a palatable buffet meal. Individual differences related to decision-making processes during the HDT were quantified with a reinforcement learning model. Path analyses were used to test whether decision-making processes that contribute to children’s (a) expected value of a choice and (b) tendency to perseverate (i.e., repeatedly make the same choice) were indirectly associated with weight status through their effects on intake (kcal). Results revealed that increases in the tendency to perseverate after a gain outcome were positively associated with intake at all three paradigms and indirectly associated with higher weight status through intake at both the standard and buffet meals. Increases in the tendency to perseverate after a loss outcome were positively associated with EAH, but only in children whose tendency to perseverate persistedacross trials. Results suggest that decision-making processes that shape children’s tendencies to repeat a behavior (i.e., perseverate) are related to laboratory energy intake across multiple eating paradigms. Children who are more likely to repeat a choice after a positive outcome have a tendency to eat more at laboratory meals. If this generalizes to contexts outside the laboratory, these children may be susceptible to obesity. By using a reinforcement learning model not previously applied to the study of eating behaviors, this study elucidated potential determinants of excess energy intake in children, which may be useful for the development of childhood obesity interventions.

Evaluation of the complementary feeding practices, dietary intake, and nutritional status of infants on a cow's milk protein elimination diet

ObjectiveTo evaluate the complementary feeding practices, food intake, and nutritional status of infants on a cow's milk protein elimination diet. MethodsA cross-sectional and observational study was conducted to compare infants aged 4–18 months who were on a cow's milk protein elimination diet with a control group of healthy infants without any dietary restrictions. General information on the child's health, demographic data, and food consumption were collected. ResultsThe study included 96 infants in the elimination diet group and 99 in the control group. In the elimination diet group, the median age (in months) of introduction of solid foods (5.0 × 4.0; p < 0.001) and water (5.5 × 4.0; p < 0.05) was later, consumption of soft drinks and industrialized cookies was less frequent (p < 0.05), and a lower index of complementary feeding inadequacies (2.75 × 3.50; p < 0.001) was observed. The elimination diet group presented lower individual values of Z scores for weight/age, weight/height, and body mass index/age, although they were fed with higher amounts of energy (117.4 × 81.3 kcal/kg of weight; p < 0.001) and macro-and micronutrients, except for vitamin A. In the elimination diet group, breast milk and its substitutes contributed to more than 67% of energy intake. Although calcium consumption was a deficit in 31.5% of the infants, none received supplementation. ConclusionInfants on an elimination diet presented more adequate complementary feeding practices and higher nutritional intake, despite lower body weight values.

Associations between ghrelin and leptin and neural food cue reactivity in a fasted and sated state

Food cue exposure can trigger eating. Food cue reactivity (FCR) is a conditioned response to food cues and includes physiological responses and activation of reward-related brain areas. FCR can be affected by hunger and weight status. The appetite-regulating hormones ghrelin and leptin play a pivotal role in homeostatic as well as hedonic eating. We examined the association between ghrelin and leptin levels and neural FCR in the fasted and sated state and the association between meal-induced changes in ghrelin and neural FCR, and in how far these associations are related to BMI and HOMA-IR. Data from 109 participants from three European centers (age 50±18 y, BMI 27±5 kg/m2) who performed a food viewing task during fMRI after an overnight fast and after a standardized meal were analyzed. Blood samples were drawn prior to the viewing task in which high-caloric, low-caloric and non-food images were shown. Fasting ghrelin was positively associated with neural FCR in the inferior and superior occipital gyrus in the fasted state. This was partly attributable to BMI and HOMA-IR. These brain regions are involved in visual attention, suggesting that individuals with higher fasting ghrelin have heightened attention to food cues. Leptin was positively associated with high calorie FCR in the medial prefrontal cortex (PFC) in the fasted state and to neural FCR in the left supramarginal gyrus in the fasted versus sated state, when correcting for BMI and HOMA-IR, respectively. This PFC region is involved in assessing anticipated reward value, suggesting that for individuals with higher leptin levels high-caloric foods are more salient than low-caloric foods, but foods in general are not more salient than non-foods. There were no associations between ghrelin and leptin and neural FCR in the sated state, nor between meal-induced changes in ghrelin and neural FCR. In conclusion, we show modest associations between ghrelin and leptin and neural FCR in a relatively large sample of European adults with a broad age and BMI range. Our findings indicate that people with higher leptin levels for their weight status and people with higher ghrelin levels may be more attracted to high caloric foods when hungry. The results of the present study form a foundation for future studies to test whether food intake and (changes in) weight status can be predicted by the association between (mainly fasting) ghrelin and leptin levels and neural FCR.

Nutrition profile and factors affecting nutrient intake of pre-liver transplant recipients

Background:Among Liver Transplantation (LT) recipients malnutrition is ubiquitous due to various metabolic aberrations and poor nutrient intake. It is imperative to recognize the diverse aspects which can alter patients’ food and nutrient intake. AimThe study aimed to provide the much-needed data on various conducive and deterrent factors for calorie and protein intake of the pre-LT patients. MethodsIn the present exploratory study 54 adult pre-LT patients were purposively selected. Information regarding patient's personal, medical history, nutrient, and dietary intake through 24- Hour Dietary recall and other factors like appetite (SNAQ), number of meals, duration of present illness, excessive fatigue, ascites, sound sleep, functional status, advice to increase intake, supplement recommended were gathered by patients’ interviews and OPD visits. ResultsThe data showed significantly lower-calorie, protein, and calcium intake among pre-LT recipients as per the recommendations (p < 0.001**). Patients were consuming more than 40% of the calories and 20% of proteins from cereals. The Stepwise forward regression analysis showed the relationship between calorie and protein intake (dependent variable) with other independent variables. Calorie intake increased by 73.4 units (p < 0.01**) with a unit increase in appetite score (SNAQ). Protein intake increased by 9.3 units with a unit increase in the number of meals consumed (p = 0.001**). Calorie and protein intake decreased by 252.8 units and 15.6 units respectively with a unit increase in the number of days dietary advice for improving the food intake was not given (p < 0.01). Also, a unit increase in the number of days patients had sound sleep, increased calorie and protein intake by 167.4 units and 10.3 units respectively (p < 0.05). ConclusionsHigher appetite, sound sleep, and higher numbers of meals consumed were conducive factors for calorie and protein intake among patients in the pre-transplant phase while no dietary advice for improving food intake was shown to be a deterrent factor. While planning diet, considerations and appropriate alterations of these factors can positively regulate the nutrient intake and nutritional status of the pre-LT patients.

Low-Intensity, High-Frequency Grazing Positively Affects Defoliating Behavior, Nutrient Intake and Blood Indicators of Nutrition and Stress in Sheep.

The intensity and frequency of grazing affect the defoliating strategy of ruminants, their daily nutrient intake, thus nutrition and physiological status. Italian ryegrass (Lolium multiflorum Lam.) pastures were grazed by sheep either under a low-intensity/high-frequency grazing strategy (Rotatinuous stocking; RN) with nominal pre- and post-grazing sward heights of 18 and 11 cm, respectively, or under a high-intensity/low-frequency strategy (traditional rotational stocking; RT) with nominal pre- and post-grazing sward heights of 25 and 5 cm, respectively. Treatments were arranged under a complete randomized design and evaluated over two periods, in different years. In 2017, the aim was to depict the type of bites that sheep perform during the grazing-down and associate them to the grazing management strategy according to their relative contribution to the diet ingested. In 2018 we estimated the total nutrient intake and evaluated blood indicators of the nutritional status and immune response to stress of sheep. The bite types accounting the most for the diet ingested by RN sheep were those performed on the “top stratum” of plants with around 20, 15, and 25 cm, whereas the type of bites accounting the most for the diet of RT sheep were those performed on “grazed plants” with around 10, 5, and ≤ 3 cm. In 2018, the RN sheep increased by 18% the total organic matter (OM) intake and by 20–25% the intake of soluble nutrients (i.e., crude protein, total soluble sugars, crude fat), digestible OM and of metabolizable energy, and had 17.5, 18, and 6.1% greater blood concentration of glucose, urea nitrogen (BUN) and albumin, respectively, but 17% lower blood neutrophil-to-lymphocyte (N:L) ratio. Sheep grazing vegetative Italian ryegrass pastures under the low-intensity/high-frequency grazing strategy (RN) ingested a diet of better quality from bites allocated on the top stratum of plants, had greater intake of soluble nutrients and blood parameters positively associated with nutritional status and immune response to stress.

Hubungan Asupan Makan dan Aktifitas Fisik Terhadap Status Gizi Anak Usia Sekolah

Abstract Health problems in children, especially in terms of nutrition, are still a problem in Indonesia such as underweight and overweight, which are caused by physical activity, and vice versa, nutritional status affects children's physical activity. Nutritional status and physical activity play an important role in achieving good physical fitness, especially for school age children. Only 1 in 3 children who are active in physical activity every day. The purpose of this study was to determine the relationship between food intake, physical activity and nutritional status in school age children. This research uses a correlational quantitative approach. Respondents who were the subjects in this study were students in grades 3-6 at SDN 2 Saparua, totaling 120 students. The number of samples used in this study was determined using the Taro Yamane or Slovin formula which resulted in 93 students. The research instruments used in this study were a 2x24 hour food recall questionnaire, anthropometric examination, physical activity questionnaire of children (PAQ-C) for physical activity and nutritional status determined using BMI / U. The research data were processed using bivariate analysis with the help of statistical products and solutions (SPSS). Correlation analysis using Pearson. The results of hypothesis testing on food intake and physical activity with a statistical value of R = 0.652; R Square = 0.425. This means that the variables of food intake and physical activity simultaneously play a role in the nutritional status of the individual by 42.5%, while the remaining 57.5% is influenced by other factors that are not disclosed in this study. The better the score of physical activity and food intake, the better the nutritional status of the child.Keywords: food intake, physical activity, nutritional status

Nutritional Status of COVID 19 Patients: Possible Impact on Mental Health Status

ObjectivesTo assess the impact of the nutritional status of COVID-19 patients on their mental health status. It is hypothesized that patients would have impaired mental health status due to compromised nutritional statusMethodsAn epidemiological, cross-sectional study included acute-severely ill COVID-19 patients in Al Madinah Al Munawarah, Saudi Arabia. The following parameters were assessed: demographic characteristics, nutritional status (using the Malnutrition Screening Tool), BMI, loss of appetite, weight loss, decreased food intake and mental health status (using the PHQ-9 to determine the severity of depression). Data collectors wore Personal Protective Equipment and spent a maximum of 15 minutes with each patient. Ethical approval was obtained from the Ministry of Health as well as patients. Statistical analysis was performed using SPSS version 26.ResultsPatients (n = 515; 82% males) were included. They aged 31–50 years old (60%), married (85%), had low education level (85%),employed in non-governmental sectors (67%), and were non-Saudis (76%). Patients complained of loss of appetite (32%), weight loss (16%), and decreased food intake (19%). A significant number were at risk (13.6%) and 1.6% had high risk of malnutrition. Patients (4%) were underweight and 45% were overweight and/or obese. The mean BMI was 25.4 (SD = 5). They (23.4%) suffered from various degrees of depression. Mild depression was most prevalent (17%) followed by moderate depression (4.3%). Moderately severe and severe depression were common among 2.1%. One way ANOVA indicated that the severity of depression associated with the loss of appetite (P < 0.0005), decreased food intake (P < 0.0005), weight loss (P < 0.0005), and BMI (P < 0.0005). Linear Multiple Regression showed that the loss of appetite (B = 0.037, 95%CI = 0.011–0.352, P = 0.037), weight loss (B = 0.114, 95%CI = 0.000–0.228, P = 0.0049), and BMI (B = 0.031, 95%CI = 0.004–0.057, P = 0.023) affected patients' severity of depression.ConclusionsPossible factors associated with depression included loss of appetite, decreased food intake, weight change and BMI. Early detection of malnutrition-related factors and depression reduces hospital stay and cost of medication. It speeds up the rate of recovery, improves health outcomes and the quality of life.Funding SourcesNo funding was received.

Involvement of children in hands-on meal preparation and the associated nutrition outcomes: A scoping review.

Emerging research has explored hands-on meal preparation as a strategy to improve children's nutrition-related outcomes. This scoping review was conducted to describe the extent of studies on children's involvement in hands-on meal preparation and the related psychosocial outcomes, actual nutrition behaviour/food consumption and weight status. Scoping review methodology was used to select relevant studies, as well as extract and collate the data. Four databases (PubMed, Google Scholar, Science Direct and Cochrane Database of Systematic Reviews) were searched from the earliest available time up to December 2020. Observational studies, experimental studies and reviews that were conducted among children aged 5-12years old and published from 2010 to 2020 were retrieved. Studies extracted involved children in hands-on healthy meal preparation activities and explored the associated nutrition outcomes. In total, 28 studies (5 observational studies, 21 experimental studies, 2 reviews) were included in the final review. Studies conducted demonstrated improvement in children's psychosocial outcomes and actual nutrition behaviour/food consumption after participating in hands-on meal preparation activities, despite differences in methodology, programme content and settings (countries/cultural origins). Limited studies assessed children's nutrients intake and weight status. The current review suggests that hands-on meal preparation comprises approach for instilling positive perceptions towards nutrition/healthy foods, potentially improving children's diet. Future studies should include the assessment of nutrient intake and weight status. The long-term sustainability of these nutrition outcomes should be explored.

A SYSTEMATIC REVIEW: ASUPAN ZAT GIZI MAKRO DAN STATUS GIZI PASIEN KANKER YANG MENJALANI KEMOTERAPI A Systematic Review: Macro Nutrient Intake and Nutritional Status of Cancer Patients Undergoing Chemotherapy

Nutrient intake in cancer patients is diff erent from other disease due to side eff ects of chemotherapy, like nausea, vomit, and appetite loss, which in the long run it have an impact on the nutritional status of patients. The study used systematic reviews to determine side eff ects of chemotherapy on macro nutrient intake and nutritional status of cancer patients in 15 literature. Those literatures were taken from articles published from 2005 to 2019 in PubMed, NCBI, and Google Scholar and all of them were using observational research design. The results of 15 literature showed, there was a decrement in macro nutrient intake including energy, carbohydrates, protein, and fat as a result of chemotherapy side eff ects such as nausea, vomit, and appetite loss. Ten of 15 literature showed the patient nutritional status was underweight, and 5 literature showed overweight and obesity due to the use of corticosteroids as supporting treatment. The future research opportunities that can be carried out a deeper analysis of the relationship of nutritional intake and changes in nutritional status of patients with longer duration for the research, measurement methods by using gold standards which are weighing food record, as well as diff erent types of cancer.

Reference Intervals in Combined Veterinary Clinical Examinations of Male Black-Spotted Pond Frogs (Pelophylax nigromaculatus).

Simple SummaryThe reference intervals (RIs) of immunity, serum components, bone mineral density (BMD), and body composition in 151 males of Pelophylax nigromaculatus were established. These analyses are easily replicable and can safely and accurately diagnose the physiological condition of animals. The use of combined examination allows for the establishment of a successful conservation strategy through the identification of conservation problems in many vertebrate groups.In conservation physiology, analyzing the physiological response of an organism to understand its ability to adapt to environmental changes is a key technique in establishing a successful conservation strategy. Veterinary clinical examinations determine the physiological condition of animals accurately and safely, and this examination is synergistic when combined. The accuracy and safety of a clinical examination makes it advantageous for use in amphibians with high species diversity and numerous endangered species. However, it is necessary to establish a reference interval (RI) for precise interpretations and identification of animals with abnormalities through individual unit testing. We have established RIs for the immunity, serum components, bone mineral density (BMD), and body composition of black-spotted pond frogs (Pelophylax nigromaculatus). Black-spotted pond frogs are a common species and are widely distributed in East Asia, with suitable characteristics for environmental monitoring. Serum was extracted from 151 male frogs to establish the RI for bacterial killing ability in order to represent immunity. We also used the serum to establish an RI of ten additional serum components to determine the nutritional status, organ function status, body osmotic pressure, and homeostasis conditions. The BMD and three body composition measures for diagnosing food intake status and nutritional condition were measured using dual energy X-ray absorptiometry. The RI was recorded as the mean ± standard deviation, median, first (25%) to third (75%) quantile range, 95% confidence interval of the mean and median, and the 95% percentile (2.5%–97.5% range) of all components. The use of combined clinical veterinary examinations aids our understanding of the physiological conditions of an individual according to biotic and abiotic factors on a complex spatiotemporal scale in an ecosystem.

A study protocol of a randomized trial evaluating the effect of using defined menu plans within an intensive personal nutritional counseling program on cardiovascular risk factors: The MoKaRi (modulation of cardiovascular risk factors) trial

ImportanceChanges in dietary habits and lifestyle can reduce the risk of cardiovascular disease which is the leading cause of death worldwide. Objectives of the MoKaRi study The MoKaRi (modulation of cardiovascular risk factors) intervention study is designed to evaluate the effectiveness and potential of the developed MoKaRi concept. The MoKaRi concept comprises three components, each designed to improve dietary behavior. The first component entails using daily menu plans to implement a defined “cardioprotective diet”. This diet consists of seasonal menu plans which are characterized by:(i) a personalized energy supply depending on his or her age, gender, level of physical activity.(ii) an adequate intake of carbohydrates, protein, fat, vitamins, minerals, and trace elements according to the guidelines of the German Society of Nutrition (DGE).(iii) a recommended intake of saturated fatty acids (SFA; < 7% of caloric intake (En%)), monounsaturated fatty acids (MUFA; > 10 En%), polyunsaturated fatty acids.(PUFA; approx. 10 En%), and long-chain n-3 PUFA (≥500 mg per day).(iv) measures to encourage consumption of vegetables and fruits, and.(v) eating more than 40 g dietary fiber every day.Half of the participants will be scheduled to consume an additional 3 g of long-chain n- 3 PUFA every day in the form of fish oil.The second component consists of regular one-on-one nutritional counseling, while a variety of further incentives make up the third component of the MoKaRi concept.The MoKaRi study will provide essential insights into the relationship between defined nutrient intake, markers of food intake and health status. Our specific aim is to investigate the influence of dietary and lifestyle choices have on cardiovascular health.The information and practical tools suitable for daily use, such as the personalized menu plans, could help to transfer knowledge on nutritional facts to the general population. In this way, the validated MoKaRi concept may contribute to the prevention and therapy of cardiovascular diseases. MethodsIn line with our power calculation, we will enroll 60 participants and randomly assign them to one of two parallel arms. Each participant will receive personalized menu plans for each day of the study and will be provided with one-on-one nutritional counseling sessions every two weeks for a study period of 20 weeks (140 days). During this period, blood samples will be taken every 14 days (11 time points) and twice during a 20-weeks follow-up period. Incentives such as a supply of foods approved according t the standards of the study, a sports program, individual feedback on study parameters reflecting health status, and group activities round off the MoKaRi concept.Low-density cholesterol is the primary outcome measure of the MoKaRi study, and the secondary endpoints comprise markers of nutrient status (e.g. fatty acid distribution in plasma and erythrocyte lipids), a metabolomic profiling, diabetes risk markers, clotting markers, and further cardiovascular risk factors, such as blood lipids, homocysteine and high-sensitive c-reactive protein.The MoKaRi study was registered before launch at ClinicalTrials.gov (identifier NCT02637778; https://clinicaltrials.gov/ct2/show/NCT02637778).