Federal Grants Research Articles

Strategic States: The Congressional Roots of Federal Grant Applications

Abstract While a large body of research explores the federal-level influences over distributive politics decisions, very little attention has been given to the active role state and local governments play in the geographic distribution of federal funds. Before presidents, legislators, and agency leaders can influence the selection of federal grants, state and local governments must expend time and resources to submit grant proposals. We focus on grant applications as our unit of analysis and advance a theory that congressional representation influences the grant application behavior of state and local governments. We analyze US Department of Transportation grant applications and awards from 2009 to 2022 and find evidence that congressional representation meaningfully influences state-level grant application behavior. States apply more aggressively for federal transportation grants when represented by senators in the Senate majority party, and states apply more efficiently for grants when represented by a senator holding an advantageous committee leadership post.

Identifying Predictors of Successful Conversion from OREF Grants to Extramural Federal Funding Among Orthopaedic Surgeons

Background: Musculoskeletal diseases are a major contributor to global human disability, but research in this area of medicine contends with chronic underfunding in the United States, receiving <2% of the National Institutes of Health (NIH) budget. The Orthopaedic Research and Education Foundation (OREF) serves as a vital nongovernmental organization, providing essential support for orthopaedic research. This study investigated the translation of various OREF grants into successful extramural federal funding discerning the clinician demographics and OREF award characteristics associated with increased chances of securing federal grants. Methods: We included OREF data from 1994 to 2020, and federal funding from the NIH, the U.S. Department of Defense (DoD), the National Science Foundation (NSF), and the Agency of Healthcare Research and Quality (AHRQ) was queried using publicly available databases: the NIH RePORTER, the DoD Defense Technical Information Center, the NSF search engine, and the AHRQ search engine. Clinician demographics and training were collected from the American Academy of Orthopaedic Surgeons roster and institution departmental websites. The successful translation of OREF grants into federal awards was assessed based on clinician gender, training, and specialty, as well as OREF grant mechanisms and characteristics; multivariable logistic regression was used to determine the likelihood of federal translation based on these predictor variables. Results: Three hundred and forty-eight OREF grants were awarded to 319 different clinicians, 23.5% of whom successfully translated their award into a federal grant. Notably, recipients of the OREF Career Development Grant (CDG) demonstrated a 48.4% translation rate to federal funding. The federal return on investment for all of the OREF grants averaged 503%, translating approximately $34 million in OREF awards into >$200 million in federal funding. Logistic regression revealed that recipients who received CDG funding, as well as orthopaedic oncologists, were more than 3 times as likely to secure federal funding than those who received grants with other mechanisms and those in other subspecialties. Conclusions: OREF fills a vital role in supporting budding orthopaedic research careers, ensuring the field’s competitiveness for federal awards on a national scale. The success rates, particularly for CDG recipients, highlight OREF’s effectiveness in identifying promising surgeon-scientists.

Policy and practice innovations in school-based mental health services

The child mental health crisis resulted in US legislative expansions of funding eligibility and access to clinical interventions in schools. In tandem with the movement to decentralize mental healthcare, we argue that schools are well-positioned to adopt place-based health care models. We describe this framework while summarizing the evidence of four priorities outlined in policy documents that promote equitable mental health access. We identify examples of federal and foundation grants aligned with implementation science, robust services, care eligibility, and workforce development. Our theory-informed discussion provides an overview of research and opportunities for school-based interventions promoting child mental health.

Cardiovascular equity and health center funding: Associations of unmet hypertension and diabetes need by race/ethnicity and federal grants at federally qualified health centers, 2014-2019.

Racial and ethnic disparities in chronic disease are a major public health priority. To determine if the amount of federal grant funding to federally-qualified health centers (FQHCs) was associated with baseline overall prevalence of uncontrolled hypertension and uncontrolled diabetes, as well as prevalence by racial and ethnic subgroup. Cross-sectional multivariate regression analysis of Uniform Data System 2014-2019, which includes clinic-level data from each FQHC regarding demographics, chronic disease control by race and ethnicity, and grant funding. Our main exposure were the average values of the prevalence of uncontrolled hypertension and uncontrolled diabetes among the overall population and by racial and ethnic group from 2014-2016. Average federal grant funding per patient from 2017-2019, as measured by annual health center funding from the Bureau of Primary Health Care (BPHC) and overall federal grant funding. We analyzed 1,205 FQHCs from 2014-2019; the average BPHC grant per patient across all FQHCs in 2019 was $168 while the average total federal grant was $184 per patient. Increasing shares of total patients with uncontrolled hypertension or uncontrolled diabetes were not associated with increased total federal grant funding in either unadjusted or adjusted analysis. Increased shares of patients who are American Indian or Alaskan Native (AI-AN) with uncontrolled hypertension and diabetes were associated with increasing total federal grant funding in both unadjusted and adjusted analysis (adjusted beta hypertension $168.3, p <0.001; adjusted beta diabetes 59.44, p = 0.02). However, cardiovascular clinical need among other racial and ethnic groups was not significantly associated with grant funding. FQHCs with higher overall rates of uncontrolled hypertension or diabetes do not receive more federal funds, and there is no significant association between federal funding levels and rates of uncontrolled blood pressure or diabetes within most racial and ethnic groups, with the exception of AI-AN populations. To narrow inequities in cardiovascular disease, HRSA should consider more explicitly targeting federal grants to clinics with higher levels of clinical need.

Exploring Immigration Detention at the Intersection of Federal Grant Funding, Sanctuary, and Political Majorities in 2015

Exploring Immigration Detention at the Intersection of Federal Grant Funding, Sanctuary, and Political Majorities in 2015

Exploring Cultural Capital in the College and Financial Aid Decision Process for the GEAR UP Federal Grant Program

This qualitative study investigates the relationship between cultural capital and financial aid in college decision-making through use of an updated model based on Perna’s (2006) cultural capital model, focusing on decision-making influences within the habitus layer. Researchers conducted focus groups and interviews, yielding (N=15) GEAR UP scholarship recipient participants. Findings from this study evidence the importance of personal and social networks, individual intuition, and trust in college decision-making, with these components often cited more frequently than traditionally cited factors beyond the habitus layer. This study serves as a model for investigating student decision-making, highlighting the importance of uplifting student voice, and as an initial investigation into the ways in which college-going students’ decision-making practices are changing.

Akron gets federal polymer grant

Akron gets federal polymer grant

Revenue Generation Trends through Sharing and Grants An Evidence from Baglung Municipality, Gandaki Province, Nepal

This paper assesses the trends of revenue generation through sharing and grants in Baglung Municipality from fiscal year 2018/19 to 2022/23. The data were gathered from a comprehensive review of financial reports, budgetary documents, revenue sharing agreements, and relevant records of the municipality, and from the opinions of the respondents using five-point Likert scale questionnaires, selecting 42 respondents from 14 wards of Baglung Municipality purposively. The obtained data were analyzed descriptively. The study shows variations in the revenue performance. This municipality has been found primarily dependent on value-added tax (VAT) revenue (54.18 % in an average), which regularly accounts for a sizable share of revenue sharing, even though revenue from real estate registration fees shows a constant increase and contributes to overall revenue sharing. Regarding grants, the allocation among different categories indicates a strong focus on equalization grants (covered 21.72 % in federal grant and 66.75 % in province grant in an average). Similarly, the study has found a turnover or new wave of representatives (69.0 % less than two years of involvement) within the local entity. The study result also indicates the multifaceted needs of the community, with a particularly strong focus on roads and water supply as per the responses of 59.5 % respondents. The current revenue sharing model promotes local development, and the distribution of revenue among different sectors is found effective. Finally, this study suggests strategies pertaining to revenue estimation methodologies, manpower planning initiatives, mitigation of risks associated with an overreliance on VAT, decisions based on needs, integration of community feedback, and diversification of revenue sources to foster long-term financial stability of this municipality.

Multi-level alignment processes in the sustainment of a youth substance use treatment model following a federal implementation initiative: A mixed method study

IntroductionGovernment agencies have identified evidence-based practice (EBP) dissemination as a pathway to high-quality behavioral health care for youth. However, gaps remain about how to best sustain EBPs in treatment organizations in the U.S., especially in resource-constrained settings like publicly-funded youth substance use services. One important, but understudied, determinant of EBP sustainment is alignment: the extent to which multi-level factors that influence sustainment processes and outcomes are congruent, consistent, and/or coordinated. This study examined the role of alignment in U.S. states' efforts to sustain the Adolescent Community Reinforcement Approach (A-CRA), an EBP for youth substance use disorders, during the COVID-19 pandemic. MethodsIn this mixed methods study, the qualitative investigation preceded and informed the quantitative investigation. We interviewed state administrators and providers (i.e., supervisors and clinicians) from 15 states that had completed a federal A-CRA implementation grant; providers also completed surveys. The sample included 50 providers from 35 treatment organizations that reported sustaining A-CRA when the COVID-19 pandemic began, and 20 state administrators. In qualitative thematic analyses, we applied the EPIS (Exploration, Preparation, Implementation, Sustainment) framework to characterize alignment processes that interviewees described as influential on sustainment. We then used survey items to quantitatively explore the associations described in qualitative themes, using bivariate linear regressions. ResultsAt the time of interview, staff from 80 % of the treatment organizations (n = 28), reported sustaining A-CRA. Providers from both sustainer and non-sustainer organizations, as well as state administrators, described major sources of misalignment when state agencies ceased technical assistance post-grant, and because limited staff capacity conflicted with A-CRA's training model, which was perceived as time-intensive. Participants described the pandemic as exacerbating preexisting challenges, including capacity issues. Sustainer organizations reported seeking new funding to help sustain A-CRA. Quantitative associations between self-rated extent of sustainment and other survey items mostly followed the pattern predicted from the qualitative findings. ConclusionsThe COVID-19 pandemic amplified longstanding A-CRA sustainment challenges, but treatment organizations already successfully sustaining A-CRA pre-pandemic largely continued. There are missed opportunities for state-level actors to coordinate with providers on the shared goal of EBP sustainment. A greater focus on alignment processes in research and practice could help states and providers strengthen sustainability planning.

Anti-Asian biases in federal grant reviews: Commentary on Yip et al. (2021).

Prior to the 2021 American Psychologist special issue "Rendered Invisible: Are Asian Americans a Model or a Marginalized Minority?" (Yip et al., 2021), only seven articles on Asian American, Native Hawaiian, and Pacific Islander (AANHPI) populations were published in the journal in 3 decades. The special issue interrogated sources of invisibility and marginalization of AANHPIs not only in the field of psychology but also in the broader national landscape. The current commentary provides a deeper dive into one of the primary drivers of AANHPI invisibility, anti-Asian biases encountered during the federal grant review process, which contributes to low funding rates and insufficient research on AANHPI communities. Despite comprising over 6% of the U.S. population, less than 1% of the National Institutes of Health's funding portfolio supports science on AANHPI populations. This qualitative study revealed thematic barriers encountered during National Institutes of Health grant reviews. A one-time survey was circulated to professional scientific networks to obtain open-ended responses regarding applicants' and reviewers' experiences proposing research with AANHPI samples, resulting in data from N = 16 respondents. Respondents were asked to indicate their role in the review process (e.g., investigator, applicant, reviewer, other) and to provide open-ended responses detailing experiences of bias. Thematic coding revealed six principal themes: (1) invalidation, (2) limited reviewer knowledge, (3) oppression Olympics, (4) White comparison groups, (5) model minority myth, and (6) homogeneity of AANHPI groups. Building off these themes, this commentary concludes with five actionable policy and institutional recommendations aimed at achieving a more inclusive national research enterprise for AANHPI investigators and communities. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Machine learning predicts cerebral vasospasm in patients with subarachnoid haemorrhage

Cerebral vasospasm (CV) is a feared complication which occurs after 20-40% of subarachnoid haemorrhage (SAH). It is standard practice to admit patients with SAH to intensive care for an extended period of resource-intensive monitoring. We used machine learning to predict CV requiring verapamil (CVRV) in the largest and only multi-center study to date. Patients with SAH admitted to UCLA from 2013 to 2022 and a validation cohort from VUMC from 2018 to 2023 were included. For each patient, 172 unique intensive care unit (ICU) variables were extracted through the primary endpoint, namely first verapamil administration or no verapamil. At each institution, a light gradient boosting machine (LightGBM) was trained using five-fold cross validation to predict the primary endpoint at various hospitalization timepoints. A total of 1750 patients were included from UCLA, 125 receiving verapamil. LightGBM achieved an area under the ROC (AUC) of 0.88>1 week in advance and ruled out 8% of non-verapamil patients with zero false negatives. Our models predicted "no CVRV" vs "CVRV within three days" vs "CVRV after three days" with AUCs=0.88, 0.83, and 0.88, respectively. From VUMC, 1654 patients were included, 75 receiving verapamil. VUMC predictions averaged within 0.01 AUC points of UCLA predictions. We present an accurate and early predictor of CVRV using machine learning with multi-center validation. This represents a significant step towards optimized clinical management and resource allocation in patients with SAH. Robert E. Freundlich is supported by National Center for Advancing Translational Sciences federal grant UL1TR002243 and National Heart, Lung, and Blood Institute federal grant K23HL148640; these funders did not play any role in this study. The National Institutes of Health supports Vanderbilt University Medical Center which indirectly supported these research efforts. Neither this study nor any other authors personally received financial support for the research presented in this manuscript. No support from pharmaceutical companies was received.

Using technical assistance to bridge the gap between policy, research, and implementation.

This case study on the Children, Youth, and Families At-Risk (CYFAR) Professional Development and Technical Assistance (PDTA) Center highlights a government-funded entity's efforts to provide technical assistance to federal grantees of the CYFAR Sustainable Community Projects (SCP) grant program. The PDTA Center aligns with and supports components of an evidence-based system for innovation support. Through these components, the system provides targeted tools, training for CYFAR SCP grantees, dedicated technical assistance in the form of coaching, and quality improvement support through the evaluation of available program data.

Impact of R1 classification on universities

ABSTRACT Universities spend a substantial amount of time vying for various awards, classifications, and rankings. One of the most sought after classifications a university can receive is ‘R1’ status from the Carnegie Classification of Institutions of Higher Education. However, little work has been done on this process and the subsequent impact of receiving R1 status on university outcomes. Using a difference in differences approach and a regression discontinuity design, we assess the impact of receiving R1 status on admissions, incoming student quality, school finances, and faculty outcomes. We find that there are no significant differences in these outcomes between R1 and R2 schools. There are several schools that gain R1 status over the period of our study. We find some evidence that applications increase after schools receive R1 status, suggesting an increase in demand. Similarly, we find increases in tuition revenue, federal grants received, and the number of full-time employees after R1 status is announced.

Do presidents favor co-partisan mayors in the allocation of federal grants? – ADDENDUM

Do presidents favor co-partisan mayors in the allocation of federal grants? – ADDENDUM

A Statewide Mobile Simulation Program For Improving Obstetric Skills in Rural Hospitals.

Closure of rural obstetric (OB) units has led to maternal care deserts, causing mothers to travel long distances for maternity care. Emergency departments (EDs) in hospitals where OB units have closed require regular training for personnel to maintain OB skills, as do rural Level-1 OB units with low volumes of maternity cases. We used a federal grant to develop an OB mobile simulation program to bring simulation-based training to rural providers. Our goal was to improve OB skills and standardize care through the framework of the Alliance for Innovation in Maternal Health (AIM) Patient Safety Bundles. We conducted needs assessments and built a mobile simulation unit. We defined 2 groups of learners: those in Level-1 OB units and those in EDs without OB units. For Level-1 OB units, we created a train-the-trainer curriculum, to create a statewide cohort of simulation experts to implement simulations in their facilities between our visits. We gifted each Level-1 unit an OB task trainer, implemented virtual train-the-trainer simulation and task trainer workshops, and conducted post-workshop assessments. We then traveled to each Level-1 unit and helped the cohort implement in situ simulations for their staff using facility-specific resources. We conducted assessments for the cohort and the hospital staff after the simulations. For EDs, we delivered virtual didactics to improve basic OB knowledge, then traveled to ED units, implemented in situ simulations, and conducted post-simulation assessments. We chose a postpartum hemorrhage (PPH) scenario for our first round of simulations. After train-the-trainer simulation workshops, 98% of participants surveyed agreed that workshop goals and objectives were achieved. After the task trainer workshop, 95% surveyed agreed that their knowledge of using the simulator had improved. After implementing in situ simulations in Level-1 OB units, 98.8% of the train-the-trainer cohort found that their ability to implement simulations had improved. The hospital staff participating in the simulations identified a 30% increase in ability to manage PPH. For the ED staff, postdidactic evaluations identified that 95.4% of participants reported moderate improvement in basic OB knowledge and after participation in the simulations >95% reported better skills as an ED team member when caring for pregnant patients. These results demonstrate improved skills of hospital staff in simulated PPH in Level-1 OB units and simulated OB emergencies in EDs that no longer have OB units. Further studies are warranted to assess improvement in maternal outcomes.

Helping addicted women and their newborns stay together and recover

Sometimes it seems there's little hope for pregnant women who are addicted to drugs, or for their families. But in fact, there is a robust literature proving that family‐based care helps keep mother and child together, and federal grants are supporting such programs.

HSP47 complements cholesterol synthesis-independent HMGCoA-reductase pathway-mediated fibroblast bioenergetics

Fibrosis, characterized by excessive extracellular matrix (ECM) components deposition, is a common pathological process underlying numerous chronic diseases. Differentiating fibroblasts into myofibroblasts leads to the deposition of fibrous proteins like collagen in the ECM. Heat shock protein 47 (HSP47) is a molecular chaperone protein that assists in the folding of collagen. Recent studies show that inhibition of cholesterol synthesis-independent HMGCoA-reductase pathway enzyme geranylgeranyl pyrophosphate synthase 1 (GGPS1) decreases fibroblast differentiation and its bioenergetics. However, the role of HSP47 in this pathway is unknown, although recent observations show that HSP47 is decreased when GGPS1 is inhibited. Hence, we tested the hypothesis that HSP47 promotes cellular respiration in myofibroblasts. Seahorse assays were performed on different fibroblasts/myofibroblasts repeatedly and the oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) were measured in the presence and absence of HSP47 inhibitor (HY124817). Complex V of the electron transport chain was measured by immunoblotting ATP-5A. HY124817 tends to decrease the OCR, basal respiration rate, ATP-linked, and spare respiratory capacity. Co-incubation with HY124817 and digeranyl bisphosphonate (DGBP), an inhibitor of GGPS1, significantly (P = 0.043) inhibited further the ATP-linked OCR compared to the TGF group. Immunoblotting showed that Complex V did not change significantly across treatments. These results suggest that HSP47 is involved in fibroblast bioenergetics related to ATP-linked OCR in both differentiated myofibroblasts and normal fibroblasts. Inhibition of HSP47 complements the decrease in myofibroblast cellular respiration caused by the GGPS1 inhibition. This finding is novel in that HSP47 plays a role in fibroblast bioenergetics regulated by the cholesterol synthesis-independent HMGCoA-reductase pathway. Further research is necessary to identify what HSP47 targets and regulatory elements involved in this process. This would provide more insight into the mechanisms that underlie critical fibrosis conditions like myocardial fibrosis and potential therapeutics. This experience was supported by the Medical College of Wisconsin's Advancing Student Potential for Inclusion with Research Experiences (ASPIRE) program. The program is funded by a federal grant from the National Heart, Lung, and Blood Institute. This is the full abstract presented at the American Physiology Summit 2024 meeting and is only available in HTML format. There are no additional versions or additional content available for this abstract. Physiology was not involved in the peer review process.

Nutritional Science at the University of Illinois at Urbana-Champaign

The University of Illinois at Urbana-Champaign (UIUC), the land-grant university for the State of Illinois, was founded in 1865, and education in nutrition was recorded as early as 1874. Herein, the contributions of the UIUC to research and graduate training in the field of nutrition are highlighted. Over the past 150 years, faculty members from many academic units have provided foundational nutrition research, including identifying the last essential amino acid, threonine, and establishing chemically defined amino acid diets for chicks, rats, dogs, and cats that led to establishing amino acid requirements for these species. Research on the adverse health effects of trans fatty acids supported their removal from the food system. UIUC has led in the area of functional foods for health, including plant bioactives, soy, and fiber. More recently, UIUC faculty have evaluated the interactions between dietary components and neurocognitive, microbiome, and health outcomes, including cancer. In 2020, the cross-campus Personalized Nutrition Initiative was launched to coordinate interdisciplinary research. The Division of Nutritional Sciences was established in 1968 as one of the country’s first interdisciplinary graduate training programs. The Division of Nutritional Sciences program has conferred over 580 degrees and has implemented innovations in graduate education, many supported by federal training grants and endowed awards and programs.

The Influence of Demographics and Workforce Innovation Opportunity Act (WIOA) Employment and Training Services on Employment Outcomes for Teenagers Receiving Supplemental Security Income (SSI) and Their Parents

Transition age youth with disabilities and their families can access a variety of Workforce Innovation Opportunity Act (WIOA)-funded employment and training services. This study evaluated the impact of these services on youth and parent employment outcomes. These services were coordinated as part of the Wisconsin Promoting Readiness of Minors in SSI (PROMISE) federal demonstration grant. Youth with disabilities receiving Supplemental Security Income (SSI) benefits were randomly assigned to ‘usual’ services, including those available through school and vocational rehabilitation (VR) transition services, or ‘enhanced’ case management and transition services through the Wisconsin PROMISE demonstration. Parents who consented to participate could receive educational, employment, and financial self-sufficiency services and support through the Family Service Plan (FSP) connected to the youth’s PROMISE VR case. Youth and parents could also choose to receive WIOA Title I and Title III employment and training services, as well as Youth Apprenticeship, available through the Wisconsin Department of Workforce Development’s Division of Employment and Training (DET). A hierarchical logistic regression analysis demonstrated that VR services predicted higher youth employment rates and DET services predicted higher youth and parent employment rates. A linear regression analysis demonstrated that PROMISE services predicted higher youth wages and DET services predicted higher youth and parent employment wages. Findings suggest the coordination of employment-focused services across programs leads to increases in employment outcomes. Limitations and implications are discussed regarding the relationship between VR services, DET employment and training services, and employment outcomes.

The Intersection of Cardiovascular Health and Maternal Health: Portfolio Analysis of Federal Grant Funding 2016-2021.

Background: The United States has high and increasing rates of maternal morbidity and mortality, large proportions of which are related to cardiovascular health (CVH). Methods: We searched for National Institutes of Health (NIH) supported research as well as that of two other Agencies in the U.S. Department of Health and Human Services (DHHS) for fiscal years (FY) 2016-2021. Grants included maternal health conditions or exposures across all pregnancy stages, but excluded grants that focused entirely on birth, neonatal, infant/childhood outcomes. Results were manually curated by reviewing the abstract and specific aims. Grants deemed to be relevant were grouped by category. Results: Between FY 2016-2021, overall Maternal Health grants remained unchanged at an average of 1.4% of total DHHS grant funding. Maternal CVH-specific (MCVH) funding amounted to $278,926,105 for 755 grants, $191,344,649 was for 534 Type-1 grants, representing a twofold increase. Non-NIH DHHS agencies most commonly funded general Maternal Health related to CVH; NIH focused funding classified as hypertensive disorders of pregnancy, maternal morbidity and mortality, obesity, and diabetes. Non-NIH DHSS Agencies most commonly funded clinical applied research. In addition to clinical applied grants, NIH funded substantial proportions of grants classified as basic research, clinical trials, and/or translational. National Heart, Lung, and Blood Institute (NHLBI) MCVH grants studied participants in the pre-partum period (78.5%), followed by the post-partum period (50.5%), with relatively few in pre-pregnancy and peri-partum periods (10.8% and 9.7%, respectively); at the NIH level, the peri-partum period had better representation at 20.3%, whereas the pre-pregnancy period remained low at 9.9%. Conclusions: Federal grant funding for maternal health including MCVH increased at the same rate as its funding for overall research, and represented only 1.4% of overall total funding. The pre-pregnancy period was understudied in overall NIH funding and represents a gap area whereby funding agencies could further foster research advances.