Let X be a smooth, complex Fano 4-fold, and ρ X its Picard number. If X contains a prime divisor D with ρ X − ρ D > 2 , then either X is a product of del Pezzo surfaces, or ρ X = 5 , 6 . In this setting, we completely classify the case where ρ X = 5 ; there are 6 families, among which one is new. We also deduce the classification of Fano 4-folds with ρ X ≥ 5 with an elementary divisorial contraction sending a divisor to a curve.
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