Family CARD Research Articles

Analisis Kebijakan Aplikasi Identitas Kependudukan Digital (IKD) Sebagai Persyaratan Pembuatan E-KTP

Public service is an essential element that reflects the quality of governance in Indonesia, particularly in population administration, which includes the issuance of important documents such as ID cards (KTP), family cards (KK), birth certificates, and death certificates. Along with technological advancements, Indonesia launched the Digital Population Identity (IKD) application to improve efficiency and reduce reliance on physical documents. This study aims to evaluate the positive public’s response of the IKD application in Singosari District, Malang Regency, as well as to identify the challenges and factors influencing the implementation of this policy. The research method used is descriptive qualitative research with approaches such as interviews, observations, and documentation. The findings show that although the IKD application facilitates the administrative process, there are still challenges such as a lack of public’s response, limited mobile device availability, and technical issues with the application. Socialization through social media and the improvement of operator capacity are key supporting factors for the success of the implementation. This study contributes theoretically to the development of E-Governance concepts and practically highlights the importance of digital education for the public. It is suggested that enhanced socialization for groups less familiar with technology, improved supporting infrastructure, and training for service operators are necessary to ensure the success of the IKD application in population administration services in Singosari District.

Implementasi Program Klampid New Generation (KNG) pada Pelayanan Administrasi Kependudukan Kelurahan Panjang Jiwo Kota Surabaya

This research aims to determine the implementation of the Klampid New Generation (KNG) Program in population administration services in Panjang Jiwo Village, Surabaya City. The Klampid New Generation (KNG) program is designed to make it easier for people to access population administration services, such as issuing birth certificates, death certificates, updating biodata on family cards, and other population documents. This research uses a qualitative descriptive method. The data collection technique was carried out using the triangulation method, namely through interviews, literature study and documentation. The research results show that the implementation of the Klampid New Generation (KNG) Program in population administration services in Panjang Jiwo Village has gone well, referring to the policy implementation theory put forward by George C. Edward III.

Majority bias in legal politics

Scholars have extensively studied discriminatory recognition of local religions; however, few have emphasised proposing solutions using legal politics as an approach. This study aims to identify the legal politics underlying the legislation on the recognition of local religions of customary communities and its implications for services in obtaining citizenship documents, such as identity cards, family cards, marriage certificates, and birth certificates. Using a socio-legal method, this research was conducted in six customary communities practising the local religions/beliefs of Sunda Wiwitan in West Java province and Adam in Central Java province as the primary data sources. Meanwhile, secondary data was gathered from three ministries and the Department of Population and Civil Registration in six districts. The results showed that the presence of majority bias-based legal politics in the legislation resulted in discrimination against local believers in acquiring citizenship documents in Indonesia. These discriminations are experienced by four communities that still adhere purely to their local religions.

IMPLEMENTASI APLIKASI WEBSITE SEKOLAH TAMAN KANAK-KANAK DEWI SARTIKA BANDUNG

Community service activities held at Dewi Sartika Bandung Kindergarten School are based on several areas for improvement in publicizing the school's activities to the community. The school only had social media such as Instagram and Facebook during its establishment. Another shortcoming is the documentation of new student registration, which still uses registration forms, hard copies of family cards, and identity cards of prospective students' parents. The effectiveness of document storage could be improved. It is still prone to data loss, so it is necessary to have digital data storage to overcome these shortcomings by creating a website that is integrated with digital prospective student data collection. The method applied to measure success in this community service activity is quantitative method, namely giving a questionnaire which is then calculating to obtain a percentage value of success from this activity. The results of community service activities carried out at the school are in the form of a website that can be accessed by teachers, parents of students, prospective school students, and public society and is expected to help with administrative work at the Dewi Sartika Bandung Kindergarten. The percentage of success of the website that has been created is in the “sufficient/normal” category, which is represented by a percentage value of 46.5 %.

Treg Cells Attenuate Pulmonary Venous Remodeling in PH-LHD via NLRC3 Signaling.

Pulmonary venous remodeling is a key pathological feature of pulmonary hypertension associated with left heart disease (PH-LHD). This study aims to investigate the role of regulatory T (Treg) cells in this process. We used mouse models with transverse aortic constriction and cell depletion of Foxp3-DTR/tdTomato mice to examine Treg cells' function around pulmonary veins in PH-LHD in vivo. To confirm the effect of Nlrc3-/- Treg cells on PH-LHD, we utilized 3 mouse models: Nlrc3 knockout mice, athymic mice, and endothelial cell lineage tracing Cdh5CreERT2+/--mT/mG+/- mice. The interaction proteins and signaling pathways of Treg cells during endothelial-to-mesenchymal transition were elucidated by protein docking prediction, coimmunoprecipitation and cocultivation of Treg cells with venous endothelial cells. Treg cells were abundant around pulmonary veins of transverse aortic constriction-induced PH-LHD and were essential for promoting inflammation resolution and inhibiting pulmonary venous remodeling. Nlrc3 expression was reduced in mice and patients with PH-LHD. NLRC3 (nucleotide-oligomerization domain-like receptor family CARD domain containing 3) deficiency inhibited Treg cell proliferation and impaired their immunosuppressive and endothelial-to-mesenchymal transition-protective effects. Mechanistically, NLRC3 interacted with TRAM (TRIF-related adaptor molecule) and regulated IRF3/NF-κB (nuclear factor-κB) p65 signaling in CD4+ T cells. NLRC3-deficient Treg cells promoted IL (interleukin)-18 expression through IRF3/NF-κB p65 signaling, and thus IL-18 secretion activated endothelial RTK (receptor tyrosine kinase) signaling, favoring endothelial-to-mesenchymal transition progression in pulmonary veins and PH-LHD progress. This process was reversible with IL-18 binding protein in vivo. NLRC3 is crucial for Treg cells to prevent pulmonary venous remodeling in PH-LHD, primarily by modulating IL-18 secretion, which inhibits endothelial-to-mesenchymal transition and thereby improves disease progression and prognosis.

Relationship between NLRC4 and TNF-α Level as a Diagnostic marker to Differentiate Periodontal disease from Healthy status

The nod-like receptor family CARD domain-including protein 4 (NLRC4) inflammasome controls the development and production of inflammtory molecules and the triggering of a reaction to threat signs of pathogen, impairment to tissues, and altered metabolism. These alterations play a part in the development of many diseases, including periodontitis. The aim of the present investigation was to estimate the salivary concentrations of NLRC4 and tumor necrosis factor-alpha (TNF-ɑ) in discriminating periodontal disese patients from individuals have a healthy periodontium and detects NLRC4 and TNF-α possible linking. Materials and Methods, this case-control study, 88 participants were split into two groups: the control group (C) consisted of healthy subjects with a healthy periodontium, while the patient group (P) consisted of subjects with periodontitis. The plaque index (PI), bleeding on probing (BOP), probing pocket depth (PPD), and clinical attachment loss (CAL) were the markers used to assess the periodontal health. All subjects' unstimulated saliva was collected, and ELISA technique was used to clarify the quantity of NLRC4 and TNF-ɑ in the salivary samples. Results the salivary levels of NLRC4 and TNF-ɑ were high significantly of periodontitis disease participants to health individuals and have significantly linked periodontal indicators. Likewise, a noteworthy connectionof NLRC4 and TNF-ɑ was observed. Conclusion in the present study findings that the salivary NLRC4 and TNF- ɑ levels are noticeably greater in patients with periodontitis. Furthermore, there was a possible association between NLRC4 and TNF- ɑ. Therefore, it was found that salivary NLRC4 and TNF- ɑ play a part in the pathophysiology of periodontitis and can be used to diagnose the disease and distinguish it from periodontal health.

The Impact and Challenges of Parak Acil Online in Banjarmasin’s E-Government Transformation

The rapid development of information and communication technology (ICT) in the Industrial 4.0 era has transformed governance globally, including in Indonesia, where e-government initiatives are a national priority. This study examines the implementation and impact of Parak Acil Online, a digital platform introduced by the Population and Civil Registration Office (Disdukcapil) in Banjarmasin, aimed at streamlining public service delivery for population documents such as e-KTP, family cards, and birth certificates. The research employs a qualitative approach, guided by the E-GovQual and Delone & McLean IS Success models, to evaluate the platform’s performance across six dimensions: Ease of Use, Trust, Functionality of Interaction Environment, Reliability, Content and Appearance, and Citizen Support. Findings reveal that Parak Acil Online significantly enhances service accessibility, transparency, and efficiency. However, challenges persist, including digital literacy gaps, infrastructure limitations, and system performance issues, such as delays and occasional crashes during peak usage. Respondents highlighted the need for improved accessibility features, real-time support tools, and enhanced backend optimization. This study contributes by providing a comprehensive evaluation framework and actionable insights for optimizing e-government platforms in developing regions. By addressing these challenges, Parak Acil Online can achieve sustainable digital transformation and serve as a benchmark for equitable public service delivery in Indonesia and beyond.

Inovasi Layanan Kependudukan Melalui Program Jemput Bola di Dinas Kependudukan dan Catatan Sipil Kabupaten Tangerang

Public administration focuses on the implementation of government through effective management, including in public services. The Population and Civil Registration Office of Tangerang Regency launched the Jemput Bola Program as an innovation in population administration. This program aims to overcome obstacles to access to services for the community, especially those who live in remote areas or have physical limitations. Through a proactive approach, Disdukcapil officers visit the community to provide services, such as making Identity Cards (KTP), Family Cards (KK), and birth certificates. This study uses a qualitative approach to analyze the implementation of the Jemput Bola Program and its impact on the quality of population administration services. The theory of diffusion of innovation by Everett M. Rogers is used as an analytical framework, focusing on five characteristics of innovation: relative advantage, appropriateness, complexity, trialability, and ease of observation. The results of the study indicate that the Jemput Bola Program provides significant benefits in terms of accessibility and speed of service. The community feels real benefits from this program, which also contributes to more accurate population data updates.

FlaA N/C attenuates radiation-induced lung injury by promoting NAIP/NLRC4/ASC inflammasome autophagy and inhibiting pyroptosis

BackgroundRadiation-induced lung injury (RILI) is the most common complication experienced by patients with thoracic tumors after radiotherapy. Among patients receiving thoracic tumor radiotherapy, 14.6–37.2% develop RILI. RILI is characterized by an acute inflammatory response; however, the exact mechanism remains unclear and an ideal drug is still lacking. In this study, we investigated the protective effects of flagellin A with linked C- and N-terminal ends (FlaA N/C) against the development of RILI.MethodsMice and bronchial epithelial cells were exposed to radiation (15 Gy) after FlaA N/C treatment. Lung injury, bronchial epithelial cell injury, and RILI were assessed by histological evaluation in vivo and cell viability and cell death detection in vitro. Pyroptosis was assessed by western blotting (WB), immunofluorescence (IF), and immunohistochemistry (IHC). To explore the molecular mechanisms by which FlaA N/C inhibits RILI, conditional Beclin 1 (Beclin1+/−) and NLR family CARD domain-containing protein 4 (Nlrc4)-knockout (Nlrc4−/−) mice were generated. An autophagy inhibitor was used for in vitro cell assays, and pyroptosis indicators were detected. Data were analyzed using one-way analysis of variance.ResultsFlaA N/C attenuated radiation-induced lung tissue damage, pro-inflammatory cytokine release, and pyroptosis in vivo and cell viability, cell death, and pyroptosis in vitro. Mechanistically, FlaA N/C activated the neuronal apoptosis inhibitory protein (NAIP)/NLRC4/apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) inflammasome, which was then degraded during Beclin 1-mediated autophagy. Deletion of the FlaA N/C D0 domain reversed the inhibitory effect of FlaA N/C on radiation-induced pyroptosis in vivo and in vitro. Similarly, Nlrc4-knockout in vivo or inhibition of autophagy in vitro eliminated the protective effects of FlaA N/C against radiation-induced pyroptosis.ConclusionsThese results indicate that FlaA N/C attenuates RILI by promoting NAIP/NLRC4/ASC inflammasome autophagy and inhibiting pyroptosis. This study provides a potential approach for RILI intervention.

PELAYANAN ADMINISTRASI DAN KEPUASAN PUBLIK: Studi Kasus Dinas Kependudukan dan Catatan Sipil Kota Kendari

The Population and Civil Registry Service provides various services such as making Resident Identity Cards, Family Cards, birth certificates, death certificates and other population documents. This research specifically evaluates the extent to which the services provided by the Kendari City Population and Civil Registry Service meet community expectations, using a survey that includes speed of service, accuracy of data, friendliness of officers, ease of access to information, and supporting facilities. The results of the research show that there are still several problems related to speed of service (14,5% or 29 respondents strongly disagree), data accuracy (8,5% or 17 respondents strongly disagree), and friendliness of officers (19% or 38 respondents strongly disagree). agree), easy access to information (10,5% or 21 respondents strongly disagree), and adequate supporting facilities (5,5% or 11 respondents strongly disagree). This research concludes that the Kendari City Population and Civil Registry Service must continue to improve service quality by making it more transparent and accountable.

Clustering Analysis of Administrative Service Types Using K-Means (Study Case: Village bojongsalam)

Advances in information technology present significant opportunities for the improvement of public services, especially in relation to the administrative functions of Bojongsalam Village. Reliance on traditional methods often leads to inefficiencies and inaccuracies in administrative processes. This research uses the K-Means algorithm to categorize administrative service data based on service type, document number, printing date, and accompanying remarks. Utilizing the Knowledge Discovery in Databases (KDD) framework, the analysis includes data selection, pre-processing, transformation, and clustering analysis conducted through RapidMiner software. The dataset consisted of 718 administrative records that had undergone a rigorous cleaning process, including attribute normalization. The analysis resulted in an optimal Davies-Bouldin Index (DBI) value of -0.498 at K = 4, with each cluster representing a different service utilization pattern. The issuance of Family Cards (KK) and Birth Certificates showed higher demand compared to other available services. This classification promotes workload optimization, fair resource allocation, and formulation of effective operational strategies. The application of the K-Means algorithm demonstrated its effectiveness in data clustering and made a significant contribution to technology-based administrative management. The findings lay a basic framework for addressing the needs of the community in a timely manner.

Silibinin alleviates house dust mite induced allergic airway inflammation by inhibiting NLRC4 inflammasome and MMP-9 expression.

Silibinin alleviates house dust mite induced allergic airway inflammation by inhibiting NLRC4 inflammasome and MMP-9 expression.

TAT-N24 enhances retinal ganglion cell survival by suppressing ZBP1-PANoptosome-mediated PANoptosis in an acute glaucoma mouse model.

TAT-N24 enhances retinal ganglion cell survival by suppressing ZBP1-PANoptosome-mediated PANoptosis in an acute glaucoma mouse model.

Emerging role of PANoptosis in kidney diseases: molecular mechanisms and therapeutic opportunities.

Kidney diseases represent a significant global public health challenge, characterized by complex pathogenesis, high incidence, low awareness, insufficient early screening, and substantial treatment disparities. Effective therapeutic options remain lacking. Programmed cell death (PCD), including apoptosis, pyroptosis, and necroptosis, play pivotal roles in the pathogenesis of various kidney diseases. In 2019, PANoptosis, a novel form of inflammatory cell death, was introduced, providing new insights into innate immunity and PCD research. Although research on PANoptosis in kidney diseases is still limited, identifying key molecules within PANoptosomes and understanding their regulatory roles is critical for disease prevention and management. This review summarizes the various forms of PCD implicated in kidney diseases, along with PANoptosomes activated by Z-DNA binding protein 1 (ZBP1), absent in melanoma 2 (AIM2), receptor-interacting protein kinase 1 (RIPK1), NOD-like receptor family CARD domain containing 12 (NLRP12), and NOD-like receptor family member C5 (NLRC5). It also reviews the advancements in PANoptosis research in the field of kidney diseases, particularly in renal tumors and acute kidney injuries (AKI). The goal is to establish a foundation for future research into the role of PANoptosis in kidney diseases.

A Review of Urf on the Distribution of Dapua Coupons During Eid Al-Adha

The background of this study is the difference the committee has been chosen as the divider of dapua coupons, will distribute the coupons in the afternoon on the day before the slaughter day, they distribute coupons from one house to another, but in the distribution of dapua coupons there are differences from one house to another, some are given 2 coupons in one family consisting of 3 people, There are 3 coupons in one family of 5 people and there are given 3 coupons in one family consisting of 7 people. When viewed in terms of habits or 'urf that usually apply in society in general, distributing qurban coupons is distributed equally. In this research method, the author conducted qualitatively, namely research carried out systematically by raising existing data in the field. Where researchers try to find information or sources that can be used as sources of research data at this writing is the head of the qurban, the committee that distributes coupons. To obtain data and material in this writing, the author immediately went to the field to get the desired data in the field by interviewing the source concerned. The results of the study concluded that the system used to distribute dapua coupons was carried out by calculating the number of families or based on KK (family cards), in terms of 'urf or custom is urf shahih, because it is in accordance with Islamic shari'a and brings fame to the community.

Application of the Weighted Sum Model Method in Determining the Location of Family Planning Counseling at the North Sumatera BKKBN

To determine the location of Family Planning Counseling automatically, this research developed a web-based decision support system using the Weighted Sum Model (WSM) method with PHP programming and a MySql database. This system uses several variables as decision support indicators such as the number of couples of childbearing age, number of contraceptive users, location accessibility, costs, number of family cards, number of family planning participants, number of children and education, with 33 alternative regencies/cities in Sumatera Utara region. Based on the analysis carried out, the results of the top 5 alternatives are regencies/cities, namely Deli Serdang (127851), Medan (103020), Langkat (67047), Simalungun (53025), and Asahan (48598). So it can be concluded that this research achieved the results expected by the BKKBN.

A Comparative Analysis of the Growth Performance, Morphological Indicators, and Transcriptome Between Two Coastal Regions of China in the Mud Crab (Scylla paramamosain)

The mud crab (Scylla paramamosain), a commercially important species in China, is widely distributed along the southeastern coast. This study compares the growth performance, morphological traits, and transcriptomic profiles of two geographically distinct populations from Sanmen County, Zhejiang (SMC) and Zhangpu County, Fujian (ZPC). Juvenile crabs collected from both regions were reared in ponds under identical conditions for 7 months. Key results showed that the SMC population exhibited significantly higher daily weight gain, specific growth rate (SGR), and propodus‐to‐cheliped length ratio compared to ZPC (p < 0.01 for both sexes). Transcriptomic analysis revealed 44 consistently upregulated differentially expressed genes (DEGs) in SMC individuals. Among these, Otop (Otopetrin 1), Smyd (SET and MYND domain containing), AM1159 (Cancer pagurus Cuticle protein AM1159), PPAF1 (PPAR gamma coactivator 1 α), and NARG2 (NMDA receptor regulated 2) were functionally linked to molting and growth regulation in crustaceans. Notably, two mTOR pathway‐associated genes (QDPR [Quinoid dihydropteridine reductase] and NLRC 3 [NLR family CARD domain containing 3]) and several energy/nutrient metabolism genes were also upregulated in SMC. Enrichment analysis identified four active KEGG pathways in SMC: “Melanogenesis,” “Riboflavin metabolism,” “Choline metabolism,” and “Ribosome biogenesis.” These findings suggest that the superior growth performance of SMC crabs may stem from enhanced molting efficiency and nutrient allocation mechanisms. While QDPR and NLRC3 are hypothesized to mediate mTOR‐driven metabolic regulation, further functional validation is required to establish their causative roles. This study provides molecular markers (Otop, Smyd, etc.) for selective breeding programs and a transcriptomic framework for understanding regional adaptation in marine crustaceans.

Implikasi Pendidikan Akibat Hukum Kartu Keluarga Tanpa Pencatatan Nikah di Padangsidimpuan.

Abstract[ This study aims to analyze the legal implications of issuing Family Cards (KK) without marriage registration in Padangsidimpuan and its impact on administrative services and public education. This phenomenon arises because a portion of the community continues to practice marriages through customary or religious ceremonies without officially registering them. The research employs a descriptive qualitative method, collecting data through interviews, observations, and documentation involving the Civil Registry Office and the relevant community members. The findings indicate that issuing Family Cards without marriage registration creates several issues, such as limited access for children to legal documents like birth certificates, which affects their ability to access formal education. Additionally, it increases the potential for legal disputes concerning inheritance and family rights. The Civil Registry Office faces challenges in accurately recording the population, which impacts the quality of public services. The study concludes by emphasizing the importance of public education and awareness regarding the benefits and obligations of marriage registration. The local government of Padangsidimpuan is advised to enhance collaboration with religious and community leaders to foster societal awareness. Furthermore, providing accessible, affordable, and user-friendly marriage registration services should be prioritized to improve compliance with official marriage registration requirements. Keywords: Educational Implications; Legal Consequences; Family Card; Marriage Registration.

Evaluasi Kerentanan Insecure Direct Object Reference pada Aplikasi Pendaftaran Sidang Universitas XYZ

This study aims to analyze and evaluate the vulnerability of Insecure Direct Object Reference (IDOR) in the thesis registration web application at XYZ University, as well as to provide improvement recommendations to enhance the security of students' personal data. The IDOR vulnerability allows unauthorized access to students' personal documents, which can jeopardize privacy and information security. Utilizing an action research methodology consisting of four stages: diagnosis, action taking, evaluation, and learning, this research identifies the URL patterns generated when students upload documents such as ID cards, family cards, birth certificates, diplomas, and photos. During the action-taking phase, the researcher conducts attacks using Burp Suite to test the vulnerability by modifying URL parameters based on the identified patterns. The testing results indicate that all documents can be accessed without proper authorization, with a status code of 200 indicating successful access. These findings underscore the necessity for stricter security improvement measures in the thesis registration application to protect students' personal data. The implications of this research highlight the importance of implementing tighter access controls and better input validation in higher education applications to prevent potential data leaks in the future. This study makes a significant contribution to enhancing information security within educational environments.

TINJAUAN PROSES PERUBAHAN NAMA DI PENGADILAN SEBAGAI HAK INDIVIDU YANG DI CATATKAN NEGARA

Name change is an individual right guaranteed by the government, allowing every citizen to manage their personal identity according to their wants and needs. This process must be carried out through formal legal procedures, as stipulated in Law Number 24 of 2013 concerning Population Administration. This study aims to analyze the implementation of name change procedures in Indonesia, focusing on Stipulation number 14/Pdt.P/PN Pbg, which rejected a name change application due to non-compliance with legal procedures. The research method used in the preparation of this study is the normative juridical approach, which specifically focuses on the analysis of norms or the application of principles in applicable law. Based on Law Number 24 of 2013, name changes require a stipulation from the district court according to the applicant's domicile. In addition, Presidential Regulation No. 96/2018 stipulates that the recording of a name change must be accompanied by a copy of the court decision, an extract of the civil registration certificate, a family card, an electronic identity card, and travel documents for foreign nationals. The applicant's application in Stipulation No. 14/Pdt. P/PN Pbg was rejected in relation to the name change application due to non-compliance with applicable legal procedures. The applicant had made several identity changes at the Population and Civil Registration Office without going through the court process, which clearly violated the existing provisions.