Objective: This study was aimed to evaluate the effect of adipose stem cell gel (SVF-gel) in facial and breast plastic surgery. Methods: A retrospective study of 60 young patients who underwent facial and breast fat transplantation from January 2017 to May 2019 in the Plastic Surgery Department of Yuebei People’s Hospital (SVF-gel transplantation group 30 cases, traditional Coleman fat transplantation group 30 cases), and analyze the patient's curative effect. Results: 60 patients were about 35 years old (34.66±8.76 years old in the SVF-gel group, 35.25±9.01 in the traditional Coleman fat transplantation group). The BMI of the SVF-gel group was 24.36±4.02, while that of the traditional Coleman fat transplantation group was 25.01±4.05. The follow-up time of 60 patients was about 8 months. The results showed that the fullness and contour of the face and breast of all patients were improved to varying degrees compared with preoperatively. The satisfaction degree of SVF-gel transplantation group was higher than that of traditional Coleman fat transplantation group. Conclusion: SVF-gel has obvious advantages over traditional fat transplantation in volume filling and rejuvenation of the face and breasts.