Triblock Copolymer F127 Research Articles

Photogeneration of Singlet Oxygen by Tetra(p-Hydroxyphenyl)porphyrins Modified with Oligo- and Polyalkylene Oxides

Mono- and diethylene oxide derivatives of tetra(p-hydroxyphenyl)porphyrin (THPP) with different conformation states are synthesized. These compounds exhibit high photosensitization activity in the generation of singlet oxygen in organic and aqueous (in the solubilized state) phases. It is shown that introducing ethylene oxide moieties into the hydroxyphenyl substituents of THPP increases its solubility in chloroform. In addition, the activity of singlet oxygen 1Δg generation in the reaction of anthracene photooxidation by THPP tetra derivatives in chloroform, where the ethylene oxide fragments are introduced into two phenyl rings and hexadecyl fragments are introduced into another two, is higher than the activity of mono- and di-modified THPP molecules with enthylene oxide molecules at one hydroxyphenyl cycle. The activity of tetra-substituted porphyrin in chloroform, however, is comparable to that of nonsubstituted tetraphenylporphyrin, considered to be one of the most active photosensitizers. The produced ethylene oxide derivatives of THPP are solubilized with pluronic F-127 (triblock copolymer of ethylene- and propylene-oxides)—one of the least toxic and effective polymeric detergents—forming water-soluble forms of the respective porphyrins. It is established that the pluronic solubilization capability (the lowest molar concentration of pluronic required for the complete transfer of porphyrin of a particular molar concentration dissolved in organic phase to the water-soluble form) is higher for asymmetrical mono- and di-derivatives of the THPP than for symmetric tetra-substituted THPP. It is shown that the activity of the solubilized water-soluble form of mono- and tetra-derivatives in tryptophan photoxidation is higher than that of unsubstituted THPP and is comparable to the activity of tetraphenylporphyrin.

Incorporation of aromas in nanostructured monolinolein-based miniemulsions: A structural investigation

Lyotropic liquid crystalline monolinolein-based particles were synthesized to study the incorporation of lactones, terpenic derivatives and polyphenols. Particularly, the influence of their solubility and composition on the lipid particle’s internal structure was investigated by small angle X-ray scattering. The monolinolein-based emulsified mesophases were stabilized by the triblock copolymer F127. Without guest molecule, the dispersion was made of Im3¯m cubosomes. γ-lactones, poorly water soluble, allowed to favour the Pn3¯msymmetry, meaning that the γ-lactones influenced the lipid water interfaces in the particles. We observed a larger lattice parameter in the case of γ-nonalactone compared to γ-decalactone, traducing a closer localization to the lipid chain for γ-decalactone. Concerning the effect of terpenic molecules, eugenol had similar impact than the γ-lactones while menthol and thymol had stronger effect, turning the structure into a hexagonal arrangement. The difference in lattice parameters for menthol and thymol is explained by the non-planar structure of menthol. The hexagonal phase was also found in the case of camphor and myrcene. The incorporation of more complex molecules, polyphenols, was also attested. The aim of this work is to investigate the ability of the particles to be used as a carrier for cosmetic actives and food aromas, and to be able to predict this efficiency in relation with the physicochemical properties of the guest molecules.

Hydrogel Cross-Linked with Dynamic Covalent Bonding and Micellization for Promoting Burn Wound Healing.

A novel hydrogel (HA-az-F127 hydrogel) formed by reacting hydrazide modified hyaluronic acid (HAAD) and benzaldehyde terminated F127 triblock copolymers (BAF127) was developed in this work. The hydrogel with dynamic covalent chemically and micellar physically double-cross-linked networks exhibited rapid gelation and shear thinning properties. Besides, the hydrogel possessed functions, such as adaptable mechanical strength, self-healability, liquid-absorption, or drainage and tissue adhesion, which are important for wound treatment. Studies on cytocompatibility and histopathology by 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl tetrazolium bromide tests, live/death staining, and cell counting kit 8 assay demonstrated excellent biocompatibility of the hydrogels. After it was applied in the deep partial-thickness burn model, the hydrogel contributed effectively in promoting burn wound repair. Therefore, the HA-az-F127 hydrogel combined multiple functions in one system, demonstrating potential application in promoting burn wound healing.

Highly Uniform Carbon Sheets with Orientation-Adjustable Ordered Mesopores

A soft-hard template-assisted method toward the unconventional free-standing ordered mesoporous carbon sheets (OMCSs) with uniform hexagonal morphology is developed by applying MgAl-layered double hydroxide (MgAl-LDH) as the hard template, triblock copolymer F127 as the soft template, and phenolic resols as the carbon sources. It is found that the surface of MgAl-LDH can induce the morphology variation of resol-F127 monomicelles, leading to the formation of vertically or horizontally aligned mesopore arrays in the OMCSs, which can in turn determine their electrochemical energy storage behaviors in supercapacitors with different configurations. In an all-solid-state supercapacitor with two face-to-face electrodes, an OMCS with vertical mesopores manifests the best performance among the samples. By contrast, in a micro-supercapacitor with in-plane film-like electrodes, an OMCS with horizontal mesopores delivers higher energy/power densities than the other OMCSs, which are also comparable to the state-of-the-art supercapacitors based on ordered mesoporous carbons. The achievement of uniform carbon sheets with orientation-adjustable mesopore arrays can help elucidate their electrochemical storage mechanism and allow the optimization of the performances according to the device configuration, thus providing a powerful tool for the manipulation of energy storage devices on the nanoscale.

Development of Pluronic® nanocarriers comprising Pheophorbide, Zn-Pheophorbide, Lapachol and β-lapachone combined drugs: Photophysical and spectroscopic studies

Therapy efficiency is ruled by a single agent, which can be enhanced using an adjuvant, increasing cell inhibition in a synergetic aspect. Taking this into account, the photosensitizers Pheophorbide and Zinc-Pheophorbide, and their physical chemical and photodynamic properties, were evaluated with Lapachol and β-lapachone drugs. They were incorporated into triblock copolymers P123 and F127 as biocompatible nanocarriers. Spectrophotometric studies showed photosensitizer monomerization in the combined formulation, a fundamental aspect for optimal photodynamic results. The apparent pKa studies of Lapachol incorporated in copolymeric micelles indicated small variations when compared to the data in a homogeneous medium (water/ethanol). This demonstrated the composition of 76% and 56% for deprotonated forms of Lapachol at the physiological pH, after administration of the formulated systems in F127 and P123, respectively. This preferential location is in the poly (ethylene oxide) interfacial bulk of the Pluronic®. The characterization of the photophysical properties of the combined systems showed an expressed decrease of fluorescence quantum yield of the PS in the β-lapachone based systems. This was attributed to greater suppression by collisions with water molecules due to variations in the accommodation region of the photosensitizer after simultaneous encapsulation. The combined system showed a decrease of singlet oxygen quantum yield due to high local micellar microviscosity and low molecular oxygen concentration. However, a five-fold increase in singlet oxygen lifetime was noted in systems within the nanostructured microenvironment, which enhances the range of photosensitizer action. The combined system showed marked thermal stability when subjected to refrigeration, which was below the critical micellar temperature for nanocarriers. This was true after subsequent reheating as well. In addition, the formulations were stored for prolonged periods in the lyophilized state that demonstrated the maintenance of the monomeric state of the photosensitizers. This is a desirable effect for photodynamic applications. The majority of the combined systems incorporated into the nanostructured microenvironment showed temporal stability for more than 96 h in an aqueous solution.

Synthesis of ordered macro-mesoporous Mg-Al composite oxides with high thermal stability and mechanical strength

Ordered macro-mesoporous Mg-Al composite oxides (denoted as OMM-MA-x) with tunable macropore size and highly homogenous distribution of Mg have been synthesized via a confined evaporation induced self-assembly method, in which triblock copolymer F127 and polystyrene colloidal crystals are utilized as templates for ordered mesoporous and macroporous structures, respectively. The resultant OMM-MA-x materials exhibit a much more ordered 2D hexagonal mesostructure constituting wall skeleton of ordered macropores and more excellent textural properties than those of ordered macro-mesoporous alumina materials. More importantly, both ordered mesostructure and macroporous structure of OMM-MA-x can be well maintained even after thermal treatment at 900 °C or pressure treatment at 15 MPa.

Aloe vera gel influence on the micellization behavior of copolymer Pluronic F127: A potential photosensitizer carrier for topical application

ABSTRACTThis work describes the influence of aloe vera gel on Pluronic F127 triblock copolymer (F127) micellization behavior. Aloe vera gel was obtained from aloe vera mucilage found in leaf pulp. F127 (20% w/w) gel and the aloe vera/F127 blend gel were obtained by using the cold method. Fourier transform infrared spectroscopy and X‐ray diffraction analyses of lyophilized samples did not show any important copolymer interaction between aloe vera gel and F127. However, in aqueous medium, the dynamic light scattering data showed that there was an important reduction in micelle size with increasing temperature of the aloe vera/F127 blend hydrogel. The differential scanning calorimetry results indicate that the aloe vera/F127 blend has a higher micellization temperature, affected by the lower dehydrating effect of the poly(propylene oxide) blocks during the micelle formation in comparison to F127 gel. The texture analyses (hardness and adhesiveness) showed that the addition of aloe vera gel did not change the Pluronic F127 gel texture properties. The photosensitizer zinc phthalocyanine (ZnPC) was incorporated into the aloe vera/F127 blend, and the results suggest that this formulation is suitable as a ZnPC delivery system for photodynamic therapy. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46191.

Fabrication of phenolic resin based desalting membrane with ordered mesostructure and excellent chlorine resistance

A novel ordered cubic mesostructured phenolic resin (PR)/F127 desalting membrane was fabricated by a spin-coating approach via the self-assembly of PR oligomer and Pluronic F127 triblock copolymer template on a polyacrylonitrile (PAN) ultrafiltration substrate. It has a thin PR/F127 desalting active layer (30nm) and negatively charged membrane surface, and It can reject 83.7% potassium sulphate under 2g/L feed solution and 2.4MPa operating pressure. The rejection to potassium citrate can be elevated to 95.6%, and corresponding permeate flux is 11.0L/m2h, suggesting good separation capability to multivalent-anion salts. Moreover, it was found that this membrane has a good selective passage for non-charged organic species. Additionally, after the membrane was partially carbonized by adding sulphuric acid, the permeate flux can be dramatically improved to 35.9L/m2h with a slight potassium citrate rejection decrease (85.4%). Furthermore, the potassium citrate rejection of the membrane can be still kept at a high level (91.7%) after being treated for 6h in NaClO aqueous solution (pH 4), indicating excellent chlorine resistance performance. This membrane also shows good resistance to acid and alkaline solutions (pH 3–9). The negatively charged membrane surface and F127 templated dense mesostructure play a key role for improving the separation capability of the PR/F127 membrane. This membrane material should have a good application prospect in multi-component separation and reclamation of oxidative waste water.

Synthesis and characterization of nanometal-ordered mesoporous carbon composites as heterogeneous catalysts for electrooxidation of aniline

The Cu, Co and Ni nanometal embedded ordered mesoporous carbons (NM-OMCs) were fabricated by a soft-template method using phenol/formaldehyde as carbon source and triblock copolymer F127 as template agent. The morphology, structure, surface physicochemical properties and pore structure of the NM-OMCs were characterized using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS) and nitrogen adsorption-desorption isotherms. Their potential application to the electrocatalytic degradation of aniline was investigated using electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV) and OH radicals generation test. Furthermore, the electrochemical oxidation process of aniline was also investigated in the presence of the OMC-based catalyst particles suspended in a Na2SO4 solution using a PbO2 anode. Results revealed that the NM-OMCs inherited the ordered mesostructure of pristine OMC and the metal nanoparticles (Cu, Co or Ni) were embedded in the carbon framework. The Cu-OMC exhibited significantly higher catalytic activity than OMC and other NM-OMCs for the electrooxidation of aniline. In electrochemical oxidation process of aniline, nearly all of aniline could be degraded after 120min of electrolysis with Cu-OMC particles as catalyst, while 89%, 92%, and 97% with OMC, Co-OMC and Ni-OMC catalysts, respectively, obviously higher than 76% of electrochemical oxidation without assistance of catalysts. After characterization of intermediates, a possible electrochemical degradation pathway of aniline was proposed.

Fabrication of new ordered mesoporous carbons from petroleum pitch by triblock copolymer direct templating method

A highly ordered mesoporous carbon nanocage (OMC) direct synthesis method is introduced in this article. Petroleum pitch is chosen as a hydrophobic carbon precursor, tetrahydrofuran (THF) is used as solvent, the triblock copolymer F127 as structure directing agent, while the liquid crystal templating (LCT) is used as the templating mechanism, and the OMC was obtained via a one-step nanocasting method. Experimental results showed that the introduction of proper amounts of petroleum pitch and THF ratio does not hamper the synthetic process of the structure of OMC, thus a uniform carbon composite is finally formed. It was found that the as-prepared nanoporous carbon has a three-dimensional 7.5 nm-sized carbon nanocage network. Such a uniform mesoporous carbon material exhibits a high Brunauer–Emmett–Teller (BET) surface area (446.9 m2 g− 1) and a total pore volume (0.6 cm3 g− 1).

Back Cover: Direct Observation of Growth and Self‐assembly of Pt Nanoclusters in Water with the Aid of a Triblock Polymer Using in situ Liquid Cell Transmission Electron Microscopy (TEM) (Chin. J. Chem. 8/2017)

The back cover picture shows schematic of direct in situ liquid cell TEM observation of electron bean induced growth and self‐assembly of nanoclusters in water with the aid of a triblock copolymer. The growth and self‐assembly of the Pt nanoclusters with the aid of triblock copolymer F127 are directly observed, and a surfactant guided nanocluster formation mechanism is proposed. Dramatic differences are found on the cluster forming behavior and final morphologies between thick and thin liquid regions. The difference in precursor availability and charging effects are attributed to the different growth behavior in different thickness regions. More details are discussed in the article by Chen et al. on page 1278–1283. image

Tunable Large Pore Mesoporous Carbons for the Enhanced Adsorption of Humic Acid.

Tunable large pore soft templated mesoporous carbons (SMC) were obtained via the organic self-assembly of resorcinol/formaldehyde with the triblock copolymer F127 and by investigating the effect of carbon precursor to surfactant (p/s) ratio and carbonization temperature on the material characteristics. The p/s ratio and carbonization temperature were varied respectively from 0.83 to 0.25 and from 400 to 1200 °C. The resulting SMCs had various average pore sizes, tunable from 7 up to 50 nm. At lower p/s ratios, the pore size increased, pore size distributions broadened, and pore volumes increased. An increase of hydrophobicity was observed at elevated carbonization temperatures. A 2D hexagonal ordered SMC with a narrow pore size distribution was obtained at a ratio of 0.83. Lower ratios (0.5 and 0.25) transformed into disordered porous carbons containing micropores, mesopores, and even macropores. The SMCs were tested for adsorption of a large organic molecule, humic acid (HA), from water. The material characteristics that significantly affected HA adsorption capacity were pore size and mass % (wt %) carbon. The novel SMCs showed an unprecedented high adsorption of HA in the entire molecular weight distribution range. SMCs with large mesopores resulted in higher maximum adsorption capacities and improved HA adsorption kinetics compared to activated carbon.

Direct Observation of Growth and Self‐assembly of Pt Nanoclusters in Water with the Aid of a Triblock Polymer Using in situ Liquid Cell Transmission Electron Microscopy (TEM)

Triblock copolymers are playing important roles in nanomaterial synthesis, and the nanomaterial forming mechanisms need to be studied in detail. In situ liquid cell transmission electron microscopy (TEM) is a powerful tool for real time observation of the dynamic growth behavior of nanomaterials in liquid with high resolution, and could be used for the above task. Here we report the observation of the growth and self‐assembly of Pt nanoclusters with the aid of an ethylene oxide‐propylene oxide‐ethylene oxide triblock copolymer (PEO‐PPO‐PEO) F127 using in situ liquid cell TEM, with the nanocluster growth and formation procedures being tracked. Nano objects were seen to appear, drift and rotate with time, and then form into certain shaped nanoclusters under the electron beam irradiation. Further interestingly, in the thicker liquid layer region, the nanoclusters appeared to be fluffy, with average size keeping increase with time, while in the thinner region, the clusters were thinner, and got densified with time. The difference in precursor availability due to liquid layer thickness and charging effects is attributed to such a phenomenon.

A differential approach towards understanding the enhanced emission induced superior bio-imaging and cytotoxicity within block copolymeric nanomicelles

Two tri-block copolymers P123 (PEO19PPO69PEO19) and F127 (PEO100PPO65PEO100) have been employed to form polymeric nanomicelles and function as potential nanocarriers for an anticancer pyrazoline derivative (PYZ) in aqueous buffer solution for biological studies. Encapsulation within these nanomicelles considerably enhanced the fluorescence of the PYZ compared to its low fluorescence in aqueous buffer medium. The effect of the micellar structures on the photophysical properties of PYZ have been demonstrated by means of steady state and time resolved fluorescence spectroscopy. Variation in hydrophilicity of the corona region was found to be a prime factor in modulating the location of the PYZ within the micelles which in turn influenced its corresponding enhanced emission and cytotoxicity. These drug encapsulated nanomicelles were found to be successfully internalized into the MCF-7 cells to demonstrate high-quality fluorescent images. The location of PYZ within the polymeric micelles influenced the CAC (Critical Aggregation Concentration)/CMC (Critical Micellar Concentration) ratio which modulated their drug release capacity resulting in a variation in their cytotoxicity.

Photocatalytic hydrogen production using mesoporous TiO2 doped with Pt

A series of mesoporous TiO2 (meso-TiO2) were synthesized using the sol-gel technique. A Pluronic F127 triblock-copolymer, a structure-directing agent, was incorporated as a soft template into the sol-gel. In addition, and during a separate synthesis, the sol-gel was doped with a Pt precursor. Semiconductors were prepared with 1.00wt.%, 2.50wt.%, 5.00wt.% Pt nominal loadings, respectively. They were calcined at 500°C and 550°C following synthesis. Morphological and structural properties were studied by: a) X-ray diffraction, b) UV–vis spectrophotometry, c) N2 adsorption-desorption (BET, BJH), and d) X-ray photoelectron spectroscopy (XPS). Optical band gap values for meso-TiO2 and Pt-meso-TiO2 were calculated by Kubelka-Munk (K-M) function coupled with Tauc plot methodology. It was observed that the prepared semiconductors displayed pore sizes in the 10–40nm range with bimodal distributions. Their photocatalytic activity for hydrogen production via water splitting was established in a Photo-CREC Water-II reactor under near-UV light irradiation. The aqueous solution contained 2% v/v ethanol, employed as a renewable organic scavenger. The prepared semiconductors showed that the mesoporous 2.50wt.% Pt-TiO2 has the highest photoactivity for hydrogen generation. This suggests the important role played by the loading of platinum as a TiO2 dopant, reducing the optical band gap, increasing electron storage and diminishing, as a result, electron-hole recombination. The measured Quantum Yield (QY), obtained using a rigorous approach, was established for the mesoporous 2.50wt.% Pt-TiO2 at a promising level of 22.6%.

Synthesis of 2D Nitrogen-Doped Mesoporous Carbon Catalyst for Oxygen Reduction Reaction

2D nitrogen-doped mesoporous carbon (NMC) is synthesized by using a mesoporous silica film as hard template, which is then investigated as a non-precious metal catalyst for the oxygen reduction reaction (ORR). The effect of the synthesis conditions on the silica template and carbon is extensively investigated. In this work, we employ dual templates—viz. graphene oxide and triblock copolymer F127—to control the textural features of a 2D silica film. The silica is then used as a template to direct the synthesis of a 2D nitrogen-doped mesoporous carbon. The resultant nitrogen-doped mesoporous carbon is characterized by transmission electron microscopy (TEM), nitrogen ad/desorption isotherms, X-ray photoelectron spectroscopy (XPS), cyclic voltammetry (CV), and rotating disk electrode measurements (RDE). The electrochemical test reveals that the obtained 2D-film carbon catalyst yields a highly electrochemically active surface area and superior electrocatalytic activity for the ORR compared to the 3D-particle. The superior activity can be firstly attributed to the difference in the specific surface area of the two catalysts. More importantly, the 2D-film morphology makes more active sites accessible to the reactive species, resulting in a much higher utilization efficiency and consequently better activity. Finally, it is noted that all the carbon catalysts exhibit a higher ORR activity than a commercial Pt catalyst, and are promising for use in fuel cells.

Cage like ordered carboxylic acid functionalized mesoporous silica with enlarged pores for enzyme adsorption

Cubic FDU-12 type mesoporous silicas with enlarged pores and carboxylic acid (–COOH) functionality in the pore channels (denoted as LP-FTC-x) are synthesized using tetraethyl orthosilicate (TEOS) and carboxyethylsilanetriol sodium salt (CES) as silica sources, Pluronic F127 triblock copolymer as template, and trimethylbenzene (TMB) as pore expander, and utilized them as supports for enzyme immobilization. When the –COOH content is increased from 0 to 30%, the pore size of LP-FTC-x decreases from 23.6 to 11.1 nm, and its particle size decreases from around 2 μm to 600–800 nm. The material exhibits a high papain adsorption capacity (895 mg g−1) with a low leaching rate at pH 8.2 due to the well-defined surface chemistry in the pore channel. The adsorption kinetics and isotherms follow the pseudo-second-order model and the Langmuir isotherm model, respectively. The excellent structural properties of LP-FTC-x are also advantageous for enhancement in stability of enzyme toward the temperature, solution pH, and incubation time variations.

TiO2 Nanostructure Synthesized by Sol-Gel for Dye Sensitized Solar Cells as Renewable Energy Source

The use of renewable materials as a constituent of a smart alternative energy such as the use of natural dyes for light harvesting needs to be developed. Synthesis of anatase titanium dioxide (TiO2) and fabrication Dye-Sensitized Solar Cell (DSSC) using dye-based of anthocyanin from purple sweet potato (Ipomoea batatas L.) as a photosensitizer had been done. Synthesis TiO2 through sol-gel process with the addition of triblock copolymer Pluronic F127 template was controlled at pH 3 whereas calcination was carried out at a temperature of 500 °C, 550 °C and 600 °C. The obtained TiO2 were analyzed by XRD, SAA, and SEM. The conclusion is anatase TiO2 obtained until annealing up to 600 °C. Self-assembly Pluronic F127 triblock copolymer capable of restraining the growth of TiO2 crystals. Retention growth of TiO2 mesoporous produces material character that can be used as builders photoanode DSSC with natural sensitizer anthocyanin from purple sweet potatoes. Based on the analysis of X-ray diffraction patterns and surface area analyser, the higher the calcination temperature the greater the size of the anatase crystals is obtained, however, the smaller its surface area. Purple sweet potato anthocyanin’s dyed on to TiO2 was obtained a good enough performance for DSSC’s and gain the optimum performance from DSSC’s system built with mesoporous TiO2 annealed 550 °C using flavylium form anthocyanin.

Salt-Induced Phase Separation to Synthesize Ordered Mesoporous Carbon by pH-Controlled Self-Assembly

Self-assemly of block copolymers (BCPs) and phenolic resin (PR) is an important method to prepare ordered mesoporous polymers (OMPs) and carbon materials (OMCs). In the process, phase separation of the BCP–PR composite is a critical step which is, however, time-consuming in aqueous solution. Here we report, for the first time, a new salt-induced phase separation strategy to achieve this goal. Triblock copolymer F127 and phenol-formaldehyde resin (PF) are used as the template and precursor, respectively, and sodium chloride (NaCl) is applied to induce the coagulation and phase separation of the F127–PF composite which is transformed to be OMC at high temperature. It is found that the maintenance of the ordered mesostructure is highly dependent on the pH of the F127–PF solution under NaCl interference. A hypothetical mechanism is proposed to explain the role of pH in the formation of ordered mesostructure when salt is introduced into the self-assembly system. The effects of pH, salt concentration, and varie...

Self-Assembly Synthesis of Large-Pore Fe/N-Codoped Ordered Mesoporous Carbon for Supercapacitor Electrode Materials

A slightly optimized method of evaporation induced self-assembly (EISA) has been used to synthesize large-pore Fe/N-codoped ordered mesoporous carbon directly by using phenolic resin as the carbon source and commercial triblock copolymer F127 as the soft template, as well as pyrrole and urea as the nitrogen source. The large-pore mesostructure was obtained by introducing FeCl3 for inducing pyrrole polymerization under acidic conditions during the self-assembly process. Meanwhile, the pore size can be adjusted through altering the molar ratio of FeCl3 to pyrrole monomer. The prepared materials have a particularly tortuous pore channel and large-pore size distributions (4 nm to18 nm), high specific surface area (288 to 496 m2·g−1) and pore volume (0.40 to 0.62 cm3·g−1). Electrochemical tests demonstrate that all samples possess excellent performance of electric double-layer capacitors and rate capability. Notably, the sample S0.5 with a pore size of 11 nm can obtain a specific capacitance of 257 F·g−1 at a current density of 1 A·g−1 and the capacitance retention of 92% after 1000 cycles at 10 A·g−1. It can be concluded that these advantages have promise to provide the new thought for large-pore mesoporous carbon materials in the application of supercapacitor electrode materials.