Experimental Group Research Articles

Evaluation of safety and efficacy of intracranial self-expanding drug-eluting stents for symptomatic intracranial atherosclerotic stenosis: a prospective, multicentre, randomised controlled, superiority clinical trial protocol

BackgroundIn-stent restenosis (ISR) is a crucial factor that affects the long-term efficacy of intracranial bare metal stent (BMS) implantation for intracranial atherosclerotic stenosis (ICAS). Patients with intracranial ISR are at...

Ameliorative effects of Edaravone against Valproic Acid-Induced kidney damage.

Valproic acid (VPA) is a well-known and increasingly documented antiepileptic drug that has been widely used in the treatment of epilepsy and/or epilepsy-related disorders. Prolonged clinical use of VPA has been reported to cause side effects such as nephrotoxicity. Edaravone (EDA) is a powerful free radical scavenger. The aim of the study was to investigate the protective effects of EDA against VPA-induced oxidative renal injury. Four experimental groups were formed by randomly assigning thirty-eight male Sprague Dawley rats. The first group, (Control Group, n = 8), consisted of healthy rats. The second group, (Group II, n = 10), comprised control rats given intraperitoneally EDA (30mg/kg/day) for seven days. The third group (Group III, n = 10) was administered intraperitoneally only VPA (500mg/kg/day) for seven days. The last group (Group IV, n = 10) was treated with VPA + EDA for seven days. On the 8th day, kidney tissues were immediately removed from rats. In kidney homogenates, reduced glutathione levels and Na/K+-ATPase, paraoxonase1 and prolidase activities were remarkably decreased while catalase, superoxide dismutase, glutathione peroxidase, glutathione reductase, myeloperoxidase, and xanthine oxidase activities and lipid peroxidation, protein carbonyl, advanced oxidized protein products, and hydroxyproline contents were notably elevated in VPA given group. Consistently, administration of EDA decreased renal degenerative changes seen in the kidney tissue of VPA given rats. Treatment with EDA in the VPA group significantly resulted in the recovery of both biochemical and histopathological alterations. As a result, EDA is potentially beneficial to revert oxidative renal damage induced by VPA.

Enhancing Children's Gross Motor Skills Through the Single Leg Balance Sandbag Game

Development motor rough child considered important, because If development motor rough child develop optimally then in a way No direct will influence behavior child daily. If growth physical and motoric child develop optimally, then activity motion child will become more ripe and more good . This research aims to to find out whether there is any influence game single leg balance sand bag on the gross motor skills of early childhood children . The research approach used is a quantitative approach with a Quasi Experimental research type which includes an experimental group and a control group. Data collection techniques include tests, observations, and documentation. Data analysis techniques used in study This is a descriptive data analysis and non-parametric statistical analysis with a population of 20. From the results of the non-parametric data analysis, it can be proven that the game single leg balance sand bag can has a significant influence on gross motor skills in children. Single leg balance sand bag game can affect gross motor skills in early childhood. This game can have a positive influence on children's gross motor skills. It is expected that with the Single leg balance sand bag game, children will be more enthusiastic in learning activities, can socialize well and develop more in children's gross motor skills

The effect of an emotional support training program on weight self-stigma and body image among women with polycystic ovary syndrome

Purpose This study aims to investigate the impact of an emotional support training program on weight self-stigma and body image among women with polycystic ovary syndrome (PCOS). Design/methodology/approach A randomized controlled trial was conducted with 200 women diagnosed with PCOS employing a pretest-posttest design. The experimental group, consisting of 100 women, participated in an emotional support training program and received an informational booklet, while the control group (100 women) received only the booklet. Pre- and post-intervention assessments were conducted using weight self-esteem and body shape questionnaires. Findings The results demonstrated a statistically significant difference in weight self-stigma and body shape scores between the experimental and control groups following the intervention. For both the immediate post-intervention test [t(198) = 31.1, p = 0.01] [t(198) = 31.1, p = 0.01] [t(198) = 31.1, p = 0.01] and [t(198) = 60.7, p = 0.01] [t(198) = 60.7, p = 0.01] [t(198) = 60.7, p =0.01], as well as the delayed post-intervention test [t(198) = 32.3, p = 0.01] [t(198) = 32.3, p = 0.01] [t(198) = 32.3, p = 0.01] and [t(198) = 70.9, p = 0.01] [t(198) = 70.9, p = 0.01] [t(198) = 70.9, p = 0.01], the experimental group exhibited lower mean scores. Specifically, the experimental group scored 20.3 ± 9.2 for immediate and 20.4 ± 9.3 for delayed assessments on weight self-stigma, and 101.2 ± 7.2 for immediate and 86.5 ± 7.6 for delayed assessments on body shape. In contrast, the control group scored 159.8 ± 6.3 for immediate and 157.6 ± 6.4 for delayed assessments, respectively. Practical implications Nurses should be aware of the adverse effects of PCOS and associated obesity on weight self-stigma and body image. They are encouraged to develop targeted emotional support training programs specifically designed to address weight self-stigma and body image concerns in women with PCOS. Originality/value This study confirms the effectiveness of an emotional support training program in mitigating the negative effects of weight-related stigma and improving body image perception.

Effect of Sensorimotor Rehabilitation Protocol on Vertical Ground Reaction Force and Loading Rate in Men with Patellofemoral Pain: A Randomized Controlled Trial

ntroduction: The change of vertical ground reaction force and loading rate rate is a important factor in causing patellofemoral pain (PFP). The aim of this study was the effect of sensory-motor exercises on the vertical ground reaction force and loading rate in patients with PFP when stair descent. Methods: A total of 30 patients with PFP participated and were randomly divided into two experimental and control groups (15 subject in each group). Over a period of twelve weeks, the experimental group engaged in sensorimotor exercises, while the control group did not receive any therapeutic intervention. Pain intensity, fear of movement, quadriceps muscle strength, knee flexion angle, components of vertical ground reaction force and loading rate were evaluated in two stages pre-test and post-test. For data analysis SPSS 16 software and the covariance statistical method were used to compare the results between groups, and the significance level was considered 0.05. Results: The analysis of covariance analysis indicated that sensorimotor exercises in the experimental group compared to the control group had a significant difference in reduced pain (P <0.001), reduced fear of movement (P <0.001), incresed quadriceps muscle strength (P <0.001), incresed knee flexion angle (P <0.001), components of vertical ground reaction force (P <0.001), and reduced loading rate (P <0.001). Conclusion: The finding suggest that the experimental group experienced a boost in in quadriceps muscle strength, leading to diminished pain and fear of movement, an increase in knee flexion angle, and enhanced active shock absorption. Consequently, there was an increase in both peak forces while the loading rate and valley force decreased.

Features of the relationship of asthenia and emotional intelligence of student volunteers at different level of their emotional burnout

The high demand for volunteering in various fields has shown the invaluable contribution that volunteers can make to the development of the social sphere. At the same time, most areas of volunteer activity are associated with high emotional stress, which, without proper support, can lead to various unfavorable psychological states, including asthenia and emotional burnout. So, the purpose of the study is to study the relationship between asthenia and emotional intelligence in student volunteers with different levels of emotional burnout. 40 volunteer students of the FSBEI HE KSMU took part in the study. The total sample was divided into two experimental groups of 13 people each (33% of the entire sample): experimental group No. 1 included student volunteers with a low level of emotional burnout, and experimental group No. 2 - with a high level. Psychodiagnostics was carried out using the Asthenic State Scale (ASS) method by L.D. Malkova (adapted by T.G. Chertova) and the “Professional Burnout” (PV) questionnaire (Russian version by N.E. Vodopyanov, E.S. Starchenkova). The study revealed relationships between indicators of asthenia and emotional exhaustion in volunteers, as well as between indicators of asthenia and emotional intelligence in volunteers with a low level of emotional burnout. Thus, increasing the level of emotional intelligence of volunteers, namely, understanding their own and others’ emotions, can act as a resource in the prevention of not only emotional burnout, but also asthenia.

Pengaruh Penerapan Model Project Based Learning Terhadap Hasil Belajar Siswa pada Mata Pelajaran Biologi Kelas X di SMA Negeri 1 Sutera

This article discusses the effect of the application of the Project Based Learning (PBL) model on student learning outcomes in biology subjects. The research method used is quantitative with a quasi-experimental design. This research was conducted in a high school by involving a group of students who were divided into two groups, namely an experimental group that applied the PBL model and a control group that used conventional methods. The instruments used are tests, observations, and questionnaires. The resulting data was analyzed using descriptive statistical tests and t-tests. The results showed that the application of PBL significantly improved students' understanding of biology concepts, critical thinking skills, and learning motivation. These findings indicate that PBL can be an effective alternative in teaching biology, increasing student engagement, and resulting in more meaningful learning

Improvement of the Meat Quality of Holstein Bulls Fed a Diet Enriched with Oregano Oil

Beef is a dominant meat commodity produced mainly from beef cattle breeds. Dairy cattle breeds are reared for milk production, but their calves could be raised to produce high quality meat subject to designated feeding. The objective here was to investigate the role of oregano oil-enriched diets on the quality characteristics of meat produced by Holstein bulls. Fifty Holstein bulls, aged 12 ± 2 months and with an average weight of 365 ± 60 kg, were used. They were equally allocated in two experimental groups (n = 25). One group (group CON) was offered a basal diet and the other (group OREG) the same diet enriched with 50 mg/kg DM of oregano oil, for a period of 90 days. Afterwards, meat samples were subjected to microbiological (1 h after slaughter), physicochemical (1st and 15th day after slaughter), and sensory analyses (15th day after slaughter). The beef of group OREG is characterized with improved color parameters and a lower malondialdehyde (MDA) production rate and content (68.52 ng/g versus 105.91 ng/g, p = 0.01). The sensory evaluation of beef revealed higher scores for group OREG in flavor (3.88 versus 3.17, p = 0.0007) and color (3.87 versus 3.21, p = 0.001), as well as higher nutritional value, which was associated with significantly higher levels of alanine, arginine, aspartic acid, histidine, isoleucine, leucine, lysine, valine, and total amino acids (p < 0.05). Thus, the results suggest that the quality of the meat of Holstein bulls can be improved when they are fed a diet enriched with oregano oil.

Small Extracellular Vesicle-Associated MiRNAs in Polarized Retinal Pigmented Epithelium.

Oxidative stress in the retinal pigmented epithelium (RPE) has been implicated in age-related macular degeneration by impacting endocytic trafficking, including the formation, content, and secretion of extracellular vesicles (EVs). Using our model of polarized primary porcine RPE (pRPE) cells under chronic subtoxic oxidative stress, we tested the hypothesis that RPE miRNAs packaged into EVs are secreted in a polarized manner and contribute to maintaining RPE homeostasis. Small EVs (sEVs) enriched for exosomes were isolated from apical and basal conditioned media from pRPE cells grown for up to four weeks with or without low concentrations of hydrogen peroxide using two sEV isolation methods, leading to eight experimental groups. The sEV miRNA expression was profiled using miRNA-Seq with Illumina MiSeq, followed by quality control and bioinformatics analysis for differential expression using the R computing environment. Expression of selected miRNAs were validated using qRT-PCR. We identified miRNA content differences carried by sEVs isolated using two ultracentrifugation-based methods. Regardless of the sEV isolation method, miR-182 and miR-183 were enriched in the cargo of apically secreted sEVs, and miR-122 in the cargo of basally secreted sEVs from RPE cells during normal homeostatic conditions. After oxidative stress, miR-183 levels were significantly decreased in the cargo of apically released sEVs from stressed RPE cells. We curated RPE sEV miRNA datasets based on cell polarity and oxidative stress. Unbiased miRNA analysis identified differences based on polarity, stress, and sEV isolation methods. These findings suggest that miRNAs in sEVs may contribute to RPE homeostasis and function in a polarized manner.

Nurse-delivered brief behavioral treatment for insomnia in cancer survivors: a randomized controlled trial.

To determine the efficacy of nurse-delivered brief behavioral treatment for insomnia (BBTI) compared to an attention control, in a heterogeneous sample of cancer survivors to reduce insomnia symptom severity. We recruited 132 participants from cancer care clinics, who had an Insomnia Severity Index (ISI) score ≥ 8. Participants were randomized into two groups: an experimental BBTI group and a healthy eating attention control group. Demographics survey at baseline, and sleep-related questionnaires, self-reported sleep diaries, and wrist-worn actigraphy at baseline, 1, 3, and 12months were collected. Statistical analyses used analysis of covariance (ANCOVA) models with two-sided 0.05 nominal significance level for treatment effect for primary outcome of insomnia severity at 1month. Participants were cancer survivors with a mean age of 63.7years, 55% female, 88.6% white, with breast, prostate, colorectal, and lung cancer. Statistically significant group differences were observed at all time points for ISI and sleep quality (ISI effect sizes 0.56, 0.59, and 0.54 respectively). Additionally, at 1month, those in insomnia remission (ISI ≤ 8) were higher for the BBTI (55.1%) compared to the control group (43.3%). Secondary outcomes from sleep diary measures (i.e., sleep efficiency, sleep onset latency, wake after sleep onset) were significant at 1month. The BBTI group was significantly effective in reducing insomnia severity and improving sleep quality over time compared to the control among cancer survivors. Clinical trials identifier: http://ClinicalTrials.gov , NCT03810365. Implementing BBTI in survivorship settings can effectively address and manage insomnia symptoms, thus bridging a crucial gap in care for cancer survivors.

The Effect of the Mobile Application on Students’ Achievement, Readiness and Technology Acceptance

The purpose of this study is to develop a mobile learning application for teaching vocabulary learning in order to support English as a foreign language education and to test its effectiveness. In this study, carried out in two phases, the multi-phase mixed method, which allows using qualitative and quantitative methods, was used. In the first phase (Phase 1), a Mobile-Assisted Language Learning (MALL) application was developed. At this phase, the study group consists of 14 students who have previously taken English courses in web-supported learning environments at a university. In accordance with the ADDIE model, a needs analysis was carried out first, the application was developed in the light of the results and in line with the opinions of the field experts, and the application was finalized with pilot studies. In the second phase of the study (Phase 2), the effectiveness of the mobile learning application was tested. For this purpose, the effects of MALL application on students' academic achievement, technology acceptance and technological readiness were examined. For this study, an experimental study lasting four weeks was conducted using a quasi-experimental design. In the experimental study, whose study group consisted of 61 students taking English courses at the same university; as pre-test and post-test, achievement tests and scales were administered to the experimental and control groups. According to the data obtained from the study, it was found that the mobile assisted language learning environment is more effective than the web supported learning environment in terms of students’ academic achievement; however, no significant difference was observed on students' acceptance levels and readiness. As a result of the research, it is recommended that MALL applications should be used to support language learning. Additionally, it is thought that this study can be a guide for researchers who want to conduct studies for developing mobile-assisted language learning applications.

Enhancing students’ writing competence and 21st-century skills simultaneously via infographics

The accelerating pace of technological trends has numerous reflections in education. Accordingly, various tools have been utilized to reap their benefits in English classes. Among others, infographics, which combine text with visually stimulating images, stand out thanks to their advantages, such as being concise and academically rewarding. Although their effects have been studied worldwide, a gap in the literature has been observed in measuring infographics’ effects on developing students’ writing and certain 21st-century skills simultaneously in Iraq. Therefore, the main purpose of this study was to gauge the role of infographics in improving university students’ writing competence and 21st-century skills. Having chosen 30 freshman students through convenience sampling from a private university in Erbil, Iraq, in the spring semester of the 2023-2024 academic year, they underwent the treatment spanning 10 weeks about writing essays. Data collection encompassed writing exams, questionnaires, and interviews in this mixed methods research design study. Data were analyzed using either SPSS 29 or NVivo. Control group students received writing instruction based on the common curriculum, whereas experimental group students’ lessons were expanded with infographics. The findings unleashed that infographic-enriched writing education yielded better results in terms of writing exams with a .002 p-value. Complementary findings also showed that certain 21st-century skills, such as critical thinking and taking initiative, were promoted. On the other hand, the achievement of the control group students was far from noticeable. The findings of this study may have various implications for interested parties who plan to integrate infographics into English classes harmoniously.

Improvement of Monacolin K and Pigment Production in Monascus by 5-Azacytidine

Monascus species are known to produce various secondary metabolites with polyketide structures, including Monacolins, pigments, and citrinin. This study investigates the effects of 5-azacytidine on Monascus M1 and RP2. The dry weight, red, yellow, and orange pigment values, and Monacolin K yield of both Monascus strains were measured, and their hyphae observed through electron microscopy. The experimental group showed higher dry weights and pigment values than the control group for both strains. However, Monacolin K production increased substantially only for Monascus M1. Electron micrographs revealed surface wrinkles and large protrusions in both strains after 5-azacytidine treatment. As a potent DNA methylation-promoting agent, 5-azacytidine is very useful for epigenetic and cancer biology studies and for studying secondary metabolism in fungi.

Effects of prebiotics on microbial diversity and abundance in young children with acute malnutrition: study protocol for a multi-centered, double-blinded randomized controlled trial.

The anti-inflammatory and antimicrobial benefits of prebiotics may present an affordable and cost-effective strategy for not only the prevention but also treatment of malnutrition. Therefore, the present trial has been designed with the aim to evaluate the role of prebiotics on the gut microbiome of severe acute malnourished (SAM) children. The study is designed as a prospective, double-blinded, triple-armed, multi-centered randomized controlled trial, with 6-59months old uncomplicated SAM children recruited to the experimental group receiving ready-to-use therapeutic food (RUTF) plus prebiotics and the active comparator group receiving RUTF plus starch for 2months duration (8weeks). Healthy children with matching age and gender will be recruited to placebo comparator group and will receive starch as a placebo during the study period. A total of 58 participants will be recruited to each arm with 1:1:1 allocation ratio following a pre-defined inclusion and exclusion criteria. The results of the gut microbiome diversity will serve as the primary outcome, while weight-for-height/length z-score, mid-upper-arm circumference, neurodevelopment assessment, and body mass accumulation will serve as the secondary outcome. Data collection and evaluations will be conducted at baseline and at the end of the trial (week 8), while the safety monitoring will be conducted at every second week. For analysis, the principles of intention-to-treat will be followed. Conclusively, the results of the present trial would provide useful insights and high-quality data for the treatment and management of SAM children by evaluating the effect of RUTF plus prebiotic on the gut microbiome diversity of children, leading to medical evidence for designing the large-scale studies. The present trial is registered at ClinicalTrials.gov with identifier No: NCT06155474 and registration date 4 December 2023.

Risk of dementia in patients with age-related medical conditions: a retrospective cohort study.

This retrospective cohort study aimed to investigate the impact of age-related medical conditions on the incidence of dementia, considering factors such as hypertension, diabetes mellitus, cerebrovascular disease, cardiovascular disease, chronic kidney disease, osteoarthritis, osteoporosis, chronic obstructive pulmonary disease, and hearing difficulties. Data from 513 640 patients at Keimyung University Dongsan Hospital were analyzed using the Observational Medical Outcomes Partnership Common Data Model. Patients with and without age-related medical conditions were assigned to experimental and control groups, respectively, with propensity score matching. Cox proportional hazards models assessed the association between each condition and dementia incidence. Hypertension, diabetes mellitus, cerebrovascular disease, cardiovascular disease, chronic kidney disease, osteoarthritis, osteoporosis, and hearing difficulties were associated with increased dementia risk. Chronic obstructive pulmonary disease showed no significant association with increased risk of dementia. Incidence rates ranged from 4.52 to 8.05 per 1000 person-years in the control group and 7.46 to 14.99 per 1000 person-years in the experimental group. Hazard ratios ranged from 1.38 to 2.36. The study highlights the importance of managing age-related medical conditions to mitigate dementia risk. Understanding these risk factors can inform preventive strategies and improve cognitive health outcomes. Problems with deidentification data analysis and the need for further multicentred studies are among the limitations of this study.

The Effectiveness of a Synchronous Online Mindfulness-Based Intervention on the Attentional Control and Mindfulness of Turkish Late Adolescents: A Mixed Methods Study

The primary goal of this study was to examine the effects of a synchronous online mindfulness-based psychoeducation program on attentional control and mindfulness levels of Turkish late adolescents and the intervention experiences of the participants. A sample of adolescents ( n = 40, Mage 16.7) was randomly assigned to experimental and control groups. There were 10 participants in each four groups. The embedded design with a convergent approach was used. The quantitive data were obtained using the Solomon four group design while the qualitative data were obtained with phenomenological approach. The mindfulness-based intervention consisting of eight sessions and seven workshops was applied online to the experimental groups. The findings revealed that the attentional control and mindfulness levels of the adolescents in the experimental groups were significantly higher compared to the adolescents in the control groups. Regarding the qualitative findings, the adolescents stated that there were improvements in their levels of attentional control, regulating emotions, self-knowledge, self-confidence, optimism, effective communication skills, academic achievement and motivation to study after the program. The findings of the follow-up test showed that improvements in attentional control and mindfulness levels of the adolescents persisted for 8 weeks. The findings showed that the mindfulness-based intervention is a promising tool for late adolescents.

Evaluating the effectiveness of low-level laser therapy in patients undergoing lower third molar extraction: A double-blinded randomized controlled trial.

The use of low-level laser is a therapeutic resource that has been widely used in medicine in general, which has properties capable of modulating inflammatory effects such as pain, edema, and trismus resulting from oral surgeries for the extraction of impacted third molars. This study aimed to evaluate the effect of laser therapy at two different wave frequencies (660nm and 808nm) in patients undergoing impacted 3rd third lower molar extraction. For this, 30 patients were selected and randomly distributed into three groups with 10 individuals each (Control Group, 660nm Group, and 808nm Group). Each participant, according to their experimental group, received irradiation before the start of each surgery and immediately after the surgical procedure. The data regarding edema, pain intensity, and trismus collected before the surgeries, immediately after, and after seven days were spreadsheeted and analyzed to determine the mean and standard deviation. After the Shapiro-Wilk normality test, differences between the experimental groups were determined using Multiple Analyses of Variance, considering a significance level of 5% (p<0.05). The results showed no statistically significant difference between the experimental groups in the analyzed items. Despite this, both groups irradiated with 660nm and 808nm frequencies experienced a reduction in the perception of postoperative pain, thus suggesting the benefit of using low-power laser therapy as an adjunct in the surgical treatment of impacted lower third molars. Despite the results showing no differences between the groups, using LLLT resulted in lower pain perception in the irradiated participants compared to those in the control group. This fact supports the use of LLLT as an adjuvant therapy in patients undergoing oral surgery procedures to remove impacted third molars.

Immunological Responses, Expression of Immune-Related Genes, and Disease Resistance of Rainbow Trout (Oncorhynchus mykiss) Fed Diets Supplied with Capsicum (Capsicum annuum) Oleoresin

A 45-day feeding study was carried out to assess the immune-stimulatory effects of capsicum oleoresin when added to rainbow trout diets. A total of 450 fish (mean weight: 155.20 ± 1.96 g) were distributed into 400 L tanks (30 fish/tank) across five experimental groups: control (CT, 0%), C7 (0.7%), C14 (1.4%), C21 (2.1%), and C28 (2.8%). Each group consisted of three replicate tanks. At the end of this period, hemato-biochemical parameters, innate immune responses, and immune-related gene expression levels were evaluated, and a histological examination of head kidney and liver sections was conducted. Finally, fish in all groups were challenged with Lactococcus garvieae and observed for an additional 20 days. The results revealed that oleoresin supplementation enhanced the immune responses of the treated fish, which was evidenced by the increased globulin, total protein, respiratory burst activity, and total immunoglobulin levels. The highest expression levels of the il-8, il-1β, TGF-β, and SAA genes was noticed in the C7 group, as compared with the results for the other groups. The IgT gene expression levels were higher in all experimental groups than in the CT group, and this increase was at the highest level in the C28 group. Following the bacterial challenge, all experimental groups displayed higher survival rates compared to that of the CT group. These values were 75.93, 72.22, 46.30, 33.33, and 29.63% in the C7, C14, C21, C28, and CT groups, respectively, with the C7 group displaying the highest survival rate among the groups. The histological examination of liver and head kidney tissues revealed that higher doses (in the C21 and C28 groups) showed an increase in cytoplasmic vacuolization, which causes adverse effects on fish health. However, the C7 group displayed normal histological structure in both tissues. Taken together, the most favorable immune responses were achieved in the C7 group, suggesting that 0.7% oleoresin could be applied to rainbow trout to boost immunity and protect the fish from diseases.

Exploration of the Application and Practice of Digital Twin Technology in Teaching Driven by Smart City Construction

Traditional engineering education cannot effectively respond to the demand for talents in the construction of smart cities. The application of digital twin technology in education is mostly based on case studies and lacks empirical tests. This study takes the practical teaching of a project-based course on smart city parks as an example to explore the action intention of graduate students to use digital twin technology consistently, and to provide a theoretical basis and teaching practice guidance to promote the rational application of digital twin technology in engineering education. This study set up a quasi-experimental design through the digital twin learning system, grouping 24 graduate students with 4 faculty members. The experimental group is digital twin-assisted practical teaching, and the control group is traditional teaching method, the experimental cycle is 12 weeks, and the total lesson time is 24 h. Secondly, combined with UTAUT2 model and TTF theory, the variable factor hypothesis was adopted as the scale design means, and the experimental validity was improved through questionnaire data analysis. Meanwhile, the influencing factors in the use of digital twin platform were recorded in detail through the process of data collection, data processing and modeling, as well as the application practice of digital twin platform. Finally, the results of the comprehensive survey data show that the graduate students in the experimental group are significantly better than the control group in terms of self-confidence, skill enhancement, learning outcomes, and learning experience. All these results provide information for course teaching practice, training professional teaching teams, optimizing innovative teaching paths, and promoting the cultivation and delivery of smart city technology talents.

Effects of positive education intervention on growth mindset and resilience among boarding middle school adolescents in China: a randomized controlled trial

IntroductionThe impact of a growth mindset and resilience on boarding middle school adolescents has received increasing attention from scholars. Nevertheless, research on how to intervene in the growth mindset, and resilience of boarding school adolescents needs further verification. The purpose of this study is to explore whether positive education intervention based on the PERMA (positive emotions, engagement, relationships, meaning, and achievement) model will help Chinese boarding middle school adolescents improve their growth mindset and resilience.MethodsThis study is a randomized controlled trial with both a control group and an experimental group, including pre-tests and post-tests. The study subjects were 167 adolescents, including 84 (n1 = 84) adolescents in the experimental group and 83 (n2 = 83) adolescents in the control group.ResultsThe results showed that adolescents under the intervention condition reported significantly improved growth mindset and resilience.DiscussionCompared with the control group, resilience significantly increased. These findings indicate that positive educational intervention is a promising approach to improve boarding adolescents ‘growth mindset and resilience.