Blood pressure responses after different interval configurations in aerobic exercise: a systematic review in adolescents and adults with type-1 diabetes.

Effects of a mobile data-based exercise intervention on postpartum depressive symptoms, maternal bonding, and infant crying: a randomized controlled trial.

<p>To evaluate and compare the effects of six exercise interventions on sprint performance and vertical jump height in soccer players using a systematic review and network meta-analysis (NMA). A comprehensive literature search was conducted across PubMed, Embase, the Cochrane Library, Web of Science, and SPORTDiscus for randomized controlled trials (RCTs) published from January 2000 to 30 September 2025. Thirty-one eligible studies were included, covering Traditional Strength Training, Plyometric Jump Training, Speed Training, Endurance Training, Flexibility Training, and Regular Training. A frequentist random-effects network meta-analysis was conducted. Outcomes were pre-specified hierarchically, with sprint performance and vertical jump height as co-primary outcomes and COD and 1RM as secondary outcomes; secondary outcomes were interpreted as supportive rather than primary evidence. Traditional Strength Training was most effective for 5-m sprint performance (SUCRA = 99.8%; MD = -0.09 s, 95% CI: -0.11 to -0.07), 20-m sprint performance (SUCRA = 89.9%; MD = -0.13 s, 95% CI: -0.20 to -0.06), and squat jump height (SUCRA = 86.2%; MD = 4.40 cm, 95% CI: 2.07 to 6.74). For the 30-m sprint, Speed Training ranked highest by SUCRA (74.2%), but the comparison with Regular Training was not statistically significant (MD = -0.16 s, 95% CI: -0.34 to 0.01). For the 40-m sprint, no intervention showed a statistically significant advantage over Regular Training. Among the pre-specified co-primary outcomes, Traditional Strength Training appears to provide the most consistent benefits for short-sprint acceleration (5-20 m) and vertical jump performance in soccer players. Evidence for 30-40 m sprint performance was uncertain, and secondary outcomes (COD and 1RM) should be interpreted as supportive rather than as the primary basis for overall effectiveness claims. These findings support prioritizing strength-oriented training when short-sprint acceleration and vertical jump performance are key goals; however, the implications should be interpreted cautiously because certainty varied across comparisons and residual uncertainty remains. The protocol for this systematic review was prospectively registered in PROSPERO (CRD42024608868).</p>

Virtual reality exercises versus high volume resistance training on body fat and blood biomarkers in obese adult females: A randomized controlled study.

Promoting and impeding factors for exercise in patients with osteopenia or osteoporosis: A systematic review.

Adiponectin and irisin regulate energy homeostasis and interact with peroxisome proliferator-activated receptor coactivator 1α (PGC-1α). However, whether they establish a signal connection via PGC-1α is unclear. In the current study, the expression of irisin was significantly decreased in the skeletal muscle of adiponectin knockout (KO) mice, accompanied by a de crease in APPL1/p38 mitogen-activated protein kinase (MAPK)/PGC-1α. However, adiponectin administration reversed this effect. In vitro, the p38 MAPK/PGC-1α signalling pathway mediated adiponectin-induced FNDC5 expression and irisin release in mouse-derived C2C12 myotube cells. Moreover, obesity caused dysregulation of the adiponectin/APPL1/p38 MAPK/PGC-1α signalling pathway in murine skeletal muscle, ultimately inhibiting irisin synthesis and secretion; meanwhile, prolonged exercise or exogenous recombinant adiponectin intervention activated this pathway in mouse skeletal muscle. This corresponded with an apparent improvement in high-fat diet-induced insulin resistance. The effect of mechanically stretching C2C12 myotube cells was consistent with in vivo findings. Hence, adiponectin upregulates irisin through the APPL1/p38MAPK/PGC-1α signalling pathway in murine skeletal muscle, which may enhance insulin sensitivity.

Effectiveness of exercise and nutrition interventions for cognitive function in older adults: A systematic review and meta-analysis.

The Effectiveness of Combining Exercise and Dietary Supplements on Cognition in Older Adults: A Narrative Review.

Effects of exercise interventions on clinical outcomes in pre-clinical and early rheumatoid arthritis: a systematic review and meta-analysis.

This study examined whether a four-week mindful exercise intervention could enhance affective responses and promote exercise intention and behavior. We also tested whether affective valence during exercise and post-exercise enjoyment predicted these outcomes. Ninety-seven insufficiently active adults in the intention or preparation stage of exercise behavior were randomly assigned to mindfulness, distraction, or control conditions. Participants engaged in low- to moderate-intensity exercise two to three times per week for four weeks while receiving a guided mindfulness audio, a neutral podcast, or no audio, respectively. Affective valence, post-exercise enjoyment, exercise intention, and exercise behavior were assessed at baseline, post-intervention, and one-month follow-up. Linear mixed-effects models showed that mindfulness was associated with higher affective valence than distraction and control, and higher enjoyment and exercise intention than distraction, with smaller or nonsignificant differences relative to control. Exercise behavior increased at post-intervention and declined at follow-up, while remaining above baseline. Mediation analyses indicated that post-exercise enjoyment, but not affective valence, significantly mediated the intervention's effect on exercise intention. Findings suggest that mindfulness during exercise enhances affective experiences and exercise intention, which may support engagement in physical activity. However, behavior changes were not sustained at follow-up, underscoring the need for strategies that maintain long-term effects.

This randomised controlled trial examined the impact of a combined stabilisation exercise (SE) and back extensor endurance exercise (BEEE) programme versus BEEE alone on pain, disability, health-related quality of life (HRQoL), sleep, function, sports performance, peak force and peak power in athletes with chronic low back pain (CLBP). Forty-eight university-level athletes with CLBP were randomly assigned to either the SE+BEEE group or the BEEE alone group. Both groups received their respective exercise interventions three times per week for 8weeks. Outcomes were assessed at baseline, 8th week, and 12-week follow-up. Repeated measures ANOVA with partial eta-squared (ηp2) effect sizes was used to evaluate group, time, and interaction effects. Significant time effects were observed across all outcomes (p<0.05). Significant time×group interactions (p<0.05) were found for pain (ηp2=0.17), disability (ηp2=0.14), functional score (ηp2=0.07), sprint (ηp2=0.45), and agility (ηp2=0.23), indicating greater improvements in the SE+BEEE group than in the BEEE alone group. Both groups improved in HRQoL, sleep, peak force and power over time with no interaction effects. Most improvements achieved after 8weeks were maintained at 12-week follow-up. While both exercise regimens yielded significant improvements, adding SEs to BEEE resulted in larger effect sizes and greater gains in key outcomes including pain, disability, function, and sports performance compared with BEEE alone, highlighting the added benefit of combined training in athletes with CLBP.

Multicomponent exercise for people at high risk of frailty in the local context

Lifestyle interventions as adjuvant treatments for depression: An umbrella review of systematic reviews and meta-analyses.

Real-time feedback-based personalized moderate-intensity aerobic brisk walking intervention using wrist-worn photoplethysmography (PPG) on mild-to-moderate depressive.

Effects of 16-week circuit training on spine structure, trunk muscle endurance, and balance in healthy women.

Systematic review of cardiovascular intervention studies in women after Preeclampsia.

Effects of line dancing and flexibility training on chronic non-specific low back pain among college students: A randomized controlled trial.

The effect of digital health interventions in older adults with frailty: a systematic review and meta-analysis.

The present study outlines the progressive power program (PPP), a structured exercise protocol developed for adults with overweight and obesity. The PPP integrates high-intensity interval training (HIIT), high-intensity functional training (HIFT), and moderate-intensity continuous training (MICT) within a progressive 12-week framework. Participants complete three 50-minute sessions per week, delivered either face-to-face or remotely, using bodyweight exercises and self-regulated pacing guided by heart rate monitoring and perceived exertion. The protocol is described in sufficient detail to ensure reproducibility and adaptability across diverse clinical, community, and online settings. Emphasising accessibility, safety, and participant autonomy, the PPP aims to reduce barriers related to equipment, supervision, and location. Standardised procedures for anthropometric, functional, and behavioural assessments reinforce methodological rigour. By combining evidence-based exercise modalities with scalable delivery strategies, the PPP offers a resource-efficient and adaptable approach to promoting physical activity and supporting weight management. Its methodological design aligns with public health priorities by addressing physical inactivity, reducing sedentary behaviour, and improving health outcomes in at-risk populations.•Designed a progressive 12-week exercise protocol incorporating HIIT, HIFT, and MICT modalities.•Assessed feasibility and reach by comparing face-to-face and remote delivery formats.•Evaluated physical, functional, and behavioural outcomes before and after the intervention.

Neoadjuvant chemoradiotherapy (NACRT) and radiotherapy (NART) are standard treatments for locally advanced rectal cancer (LARC). However, their associated toxicities negatively affect patients' quality of life (QoL), prompting growing interest in exercise as a supportive intervention. This critical narrative review synthesised evidence on exercise interventions delivered before, during, or after NACRT/NART, with a focus on feasibility, safety, functional, psychosocial, and emerging oncological outcomes. A systematic literature search was conducted across MEDLINE, CINAHL Ultimate, and SPORTDiscus (2010-2025). Prospective studies evaluating exercise-based interventions in patients with LARC receiving NACRT or NART were included. Studies were selected using the Participants, Exposure, and Outcome framework, and methodological quality was appraised using Critical Appraisal Skills Programme checklists. Data were synthesised narratively in accordance with PRISMA reporting standards. Sixteen studies met the inclusion criteria. Interventions varied in type, intensity, supervision, and timing. Of these, nine studies (n = 226) were analysed quantitatively. Feasibility outcomes varied widely across studies: Eligibility (27.1-100%), recruitment (27.5-90.0%), attendance (74.0-96.0%), attrition (0-100%). No serious adverse events were reported. Consistent improvements were observed cardiorespiratory fitness, strength, fatigue, QoL. Limited evidence suggested a potential association between post-NACRT exercise and tumour regression; however, some of these findings were not powered for oncological endpoints. Exercise is a feasible and safe adjunct to treatment in LARC. Further research should explore oncological outcomes and improve representation across demographics.