Exact Replication Research Articles

Maybe Waiting is Bad: A Replication Investigating Website Delay, Familiarity, and Breadth

This study is an exact replication of an experiment investigating the impacts of website design on users’ ability to use a website and their opinion of the website (Galletta et al., 2006). The replication confirms the importance of website design features, specifically delay, breadth, and familiarity on users’ ability to use and form an opinion of a website. However, the replication did not confirm the main finding, that it is the interplay of these three variables, i.e., cognitive cost, that predict performance and attitude. The original study’s findings indicate that the relationship between website design features and intention to use is fully mediated by attitude toward the website. However, the replication indicates that behavioral intentions are partially mediated by attitude toward the website. That our findings are somewhat inconsistent with those of the original study provides further support for the importance of replications.

Duration to Establish an Emergency Vascular Access and How to Accelerate It: A Simulation-Based Study Performed in Real-Life Neonatal Resuscitation Rooms.

To compare the duration to establish an umbilical venous catheter and an intraosseous access in real hospital delivery rooms and as a secondary aim to assess delaying factors during establishment and to provide recommendations to accelerate vascular access in neonatal resuscitation. Retrospective analysis of audio-video recorded neonatal simulation training. Simulation training events in exact replications of actual delivery/resuscitation rooms of 16 hospitals with different levels of care (Austria and Germany). Equipment was prepared the same way as for real clinical events. Medical teams of four to five persons with birth-related background (midwives, nurses, neonatologists, and anesthesiologists) in a realistic team composition. Audio-video recorded mannequin-based simulated resuscitation of an asphyxiated newborn including the establishment of either umbilical venous catheter or intraosseous access. The duration of access establishment (time from decision to first flush/aspiration), preparation (decision to start of procedure), and the procedure itself (start to first flush/aspiration) was significantly longer for umbilical venous catheter than for intraosseous access (overall duration 199 vs 86 s). Delaying factors for umbilical venous catheter establishment were mainly due to the complex approach itself, the multitude of equipment required, and uncertainties about necessary hygiene standards. Challenges in intraosseous access establishment were handling of the unfamiliar material and absence of an intraosseous access kit in the resuscitation room. There was no significant difference between the required duration for access establishment between large centers and small hospitals, but a trend was observed that duration for umbilical venous catheter was longer in small hospitals than in centers. Duration for intraosseous access was similar in both hospital types. Vascular access establishment in neonatal resuscitation could be accelerated by infrastructural improvements and specific training of medical teams. In simulated in situ neonatal resuscitation, intraosseous access is faster to establish than umbilical venous catheter. Future studies are required to assess efficacy and safety of both approaches in real resuscitation settings.

Does health informatics have a replication crisis?

ObjectiveMany research fields, including psychology and basic medical sciences, struggle with poor reproducibility of reported studies. Biomedical and health informatics is unlikely to be immune to these challenges. This paper explores replication in informatics and the unique challenges the discipline faces.MethodsNarrative review of recent literature on research replication challenges.ResultsWhile there is growing interest in re-analysis of existing data, experimental replication studies appear uncommon in informatics. Context effects are a particular challenge as they make ensuring replication fidelity difficult, and the same intervention will never quite reproduce the same result in different settings. Replication studies take many forms, trading-off testing validity of past findings against testing generalizability. Exact and partial replication designs emphasize testing validity while quasi and conceptual studies test generalizability of an underlying model or hypothesis with different methods or in a different setting.ConclusionsThe cost of poor replication is a weakening in the quality of published research and the evidence-based foundation of health informatics. The benefits of replication include increased rigor in research, and the development of evaluation methods that distinguish the impact of context and the nonreproducibility of research. Taking replication seriously is essential if biomedical and health informatics is to be an evidence-based discipline.

Limitations of translation activation in masked priming: Behavioural evidence from Chinese-English bilinguals and computational modelling

Electrophysiological and behavioural evidence suggests that Chinese translations of English words are automatically activated when Chinese-English bilinguals read English words (e.g., Thierry & Wu, 2007; Wu & Thierry, 2010; Zhang, van Heuven, & Conklin, 2011). The present study investigated the impact of translation activation in three behavioural experiments with in total 118 Chinese-English bilinguals. First, we investigated whether Chinese phonology was the source of the effects of Chinese character repetition in the Chinese translations of English masked primes and targets (hidden repetition priming) observed in Zhang et al.’s (2011), and whether these hidden repetition priming effects were affected by Chinese morpheme complexity and prime duration. However, we failed to find any evidence of hidden repetition priming. An exact replication of Zhang et al. (2011) was conducted next, which again provided no evidence for hidden repetition priming. However, cross-language priming data collected with the same group of participants did reveal masked translation priming and crucially Chinese character repetition priming with masked Chinese primes and English targets (partially hidden repetition priming), indicating that the activation of Chinese translations in the masked priming paradigm is limited to English target words. Computational modeling work provided further support that translation form activation is limited to target words in the masked priming paradigm.

Replication in Second Language Research: Narrative and Systematic Reviews and Recommendations for the Field

AbstractDespite its critical role for the development of the field, little is known about replication in second language (L2) research. To better understand replication practice, we first provide a narrative review of challenges related to replication, drawing on recent developments in psychology. This discussion frames and motivates a systematic review, building on syntheses of replication in psychology, education, and L2 research. We coded 67 self‐labeled L2 replication studies found across 26 journals for 136 characteristics. We estimated a mean rate of 1 published replication study for every 400 articles, with a mean of 6.64 years between initial and replication studies and a mean of 117 citations of the initial study before a replication was published. Replication studies had an annual mean of 7.3 citations, much higher than averages in linguistics and education. Overlap in authorship between initial and replication studies and the availability of the initial materials both increased the likelihood of a replication supporting the initial findings. Our sample contained no direct (exact) replication attempts, and changes made to initial studies were numerous and wide ranging, which likely obscured, if not undermined, the interpretability of replication studies. To improve the amount and quality of L2 replication research, we propose 16 recommendations relating to rationale, nomenclature, design, infrastructure, and incentivization for collaboration and publication.Open PracticesThis article has been awarded Open Materials and Open Data badges. All materials and data are publicly accessible via the IRIS Repository athttps://www.iris-database.org/iris/app/home/detail?id=york:934328. Learn more about the Open Practices badges from the Center for Open Science:https://osf.io/tvyxz/wiki.

Synthesis of N-Doped Mesoporous Carbon Nanorods through Nano-Confined Reaction: High-Performance Catalyst Support for Hydrogenation of Phenol Derivatives.

Traditional hard-template methods for the preparation of mesoporous carbon structures have been well developed, but there are difficulties associated with complete filling of the organic precursors in ordered mesochannels and exact replication of the templates. Herein, mesoporous carbon nanorods (meso-CNRs) were synthesized through thermal condensation of furfuryl alcohol followed by the nano-confined decomposition of polyfurfuryl alcohol in silica nanotubes (SiO2 NTs) with porous shells. Limited and slow release of gaseous water through the porous shells and finite polyfurfuryl precursor inside silica nanotubes are responsible for the formation of the mesoporous structures. Nitrogen can be doped into the meso-CNRs by adding guanidine hydrochloride to the precursors. The nitrogen dopant not only stabilizes the ultrasmall and active Pd nanocatalyst in the meso-CNRs but also increases the electron density of Pd and accelerates the dissociation of H2 , both of which increase the catalytic activity of the Pd catalyst in hydrogenation reactions.

Wideband multi-stage CROW filters with relaxed fabrication tolerances.

We present wideband and large free spectral range optical filters with steep passband edges for the selection of adjacent WDM communication channels that can be reliably fabricated with mainstream silicon photonics technology. The devices are based on three cascaded stages of coupled resonator optical waveguides loaded on a common bus waveguide. These stages differ in the number of resonators but are implemented with exactly identical unit cells, comprised of a matched racetrack resonator layout and a uniform spacing between cells. The different number of resonators in each stage allows a high rejection in the through port response enabled by the interleaved distribution of zeros. Furthermore, the exact replication of a unique cell avoids the passband ripple and high lobes in the stopband that typically arise in apodized coupled resonator optical waveguide based filters due to fabrication and coupling induced variations in the effective path length of each resonator. Silicon photonics filters designed for the selection of 9 adjacent optical carriers generated by a 100 GHz free spectral range comb laser have been successfully fabricated with 248 nm DUV lithography, achieving an out-of-band rejection above 11 dB and an insertion loss of less than 0.5 dB for the worst channels.

Belief, delusion, hypnosis, and the right dorsolateral prefrontal cortex: A transcranial magnetic stimulation study

According to the Two-Factor theory of delusional belief (see e.g. Coltheart at al., 2011), there exists a cognitive system dedicated to the generation, evaluation, and acceptance or rejection of beliefs. Studies of the neuropsychology of delusion provide evidence that this system is neurally realized in right dorsolateral prefrontal cortex (rDLPFC).Furthermore, we have shown that convincing analogues of many specific delusional beliefs can be created in nonclinical subjects by hypnotic suggestion and we think of hypnosis as having the effect of temporarily interfering with the operation of the belief system, which allows acceptance of the delusional suggestions. If the belief system does depend on rDLPFC, then disrupting the activity of that region of the brain by the application of repetitive transcranial magnetic stimulation (rTMS) will increase hypnotizability. Dienes and Hutton (2013) have reported such an experiment except that it was left DLPFC to which rTMS was applied. An effect on a subjective measure of hypnotizability was observed, but whether there was an effect on an objective measure could not be determined.We report two experiments. The first was an exact replication of the Dienes and Hutton experiment; here we found no effect of rTMS to lDLPFC on any hypnotic measure. Our second experiment used rTMS applied to right rather then left DLPFC. This right-sided stimulation enhanced hypnotizability (when hypnotic response was measured objectively), as predicted by our hypothesis.These results imply a role for rDLPFC in the cognitive process of belief evaluation, as is proposed in our two-factor theory of delusion. They are also consistent with a conception of the acceptance of a hypnotic suggestion as involving suspension of disbelief.

The importance of exact conceptual replications.

Although Zwaan et al. argue that original researchers should provide a replication recipe that provides great specificity about the operational details of one's study, I argue that it may be as important to provide a recipe that allows replicators to conduct a study that matches the original in as many conceptual details as possible (i.e., an exact conceptual replication).

Exact Replication of the Best Rebalancing Rule in Hindsight

This paper prices the financial derivative whose payoff is the wealth that would have accrued to a $1 deposit into the best continuously-rebalanced portfolio in hindsight. For the market with a risk-free bond and a single stock in geometric Brownian motion, Cover and Ordentlich (1998) priced this derivative at time-0, for unlevered hindsight optimization. This paper reports the price under levered hindsight optimization, at any time, for any number of correlated stocks. In this context, I show that the replicating strategy amounts to nothing more than using the best rebalancing rule in hindsight over the currently known price history. The reported price matches the O(T^(n/2)) cost of universality derived by Cover in his “universal portfolio theory” (1986, 1991, 1996, 1998), which super-replicates the same derivative in discrete time. The replicating strategy compounds its money at the same asymptotic rate as the best levered rebalancing rule in hindsight, thereby beating the market asymptotically. Naturally enough, we find that American-style versions of this derivative will never be exercised early in equilibrium.

Revisiting white backlash: Does race affect death penalty opinion?

Peffley and Hurwitz’s article “Persuasion and resistance: Race and the death penalty in America” is an influential study demonstrating the effects of race on death penalty attitudes. White respondents were found to increase their approval for capital punishment when informed that it disproportionately affects African-Americans. We present results from two studies, including one conducted on a nationally representative sample, that fail to find support for this finding. Our first study, which was conducted on Amazon Mechanical Turk, consists of an exact replication as well as an additional manipulation that strengthens the treatment by adding information about a specific black (versus a white) defendant to the stimulus. However, we fail to elicit the backlash effect found in the original study using either manipulation despite having nearly three times the sample size. These findings are mirrored by replication data from a Time-sharing Experiments for the Social Sciences survey that closely replicates Peffley and Hurwitz’s race framing treatment. The results from these studies suggest that the relationship between racial stimuli and death penalty support has changed since the original study, that racial backlash effects in this policy domain are not as robust as previously assumed, or both.

Una temporalidad en mosaico: nuevas dinámicas del sistema matrimonial y de género en la China urbana contemporánea

Contemporary Chinese society has witnessed ongoing complex institutional and cultural reconfiguration, driven by the transition from the socialist planned economy to marketization and later its deep engagement in globalization and neoliberalism. In this reshaping of Chinese society, tradition and modernity, the resurgence of patriarchal Confucian tradition, the socialist version of modernity, the capitalist version of modernity, and the socialist heritage intermingle, and all seem to define a mosaic temporality.Facing the increasing uncertainties of the market, family members in post-reform China have to stick together as an economic safety net, emotional harbor and spiritual fortress. Chinese parents heavily invest in their children and continue to support them in their adulthood; whereas, the youth is under great obligation to providing old age care for their parents; and parents may regard this heavily-invested offspring as their private product. This resurgent but modified familialism, is not an exact replication of traditional familialism, but is definitely different from the family modes featured by individualism in Western contexts. Mosaic familialism is characterized by a sequential symbiosis between parents and children facing financial constraints and unforeseeable uncertainties with a lack of a social safety net. At the same time, patriarchal Confucianism is rejuvenated to a certain degree, women’s traditional wife and mother role is once again stressed, if not glorified; and the neoliberal discourse articulating personal choice and responsibility, but not individual right, stands by seamlessly. Parents and children, husband and wife are dependent on each other in the intimate family, following a clearly gendered pattern.

Intergroup threat, social dominance, and the malleability of ideology: The importance of conceptual replication

AbstractConsistent with the theory of malleable ideology, research has shown that, under intergroup threat, antiegalitarian individuals will exploit the malleable character of color blindness and strategically claim to be strong supporters of it. In three studies conducted in France, we found no support for this theory when measuring color blindness but strong support when using measures of laïcité, an ideology of secularism. Indeed, those who score low on social dominance orientation (SDO) were more likely to support laïcité than antiegalitarian individuals. However, a situational threat (Study 1), a symbolic threat experimentally induced (Study 2), and a perceived symbolic threat (Study 3) were all related to increased support for laïcité by people high in SDO, without affecting those low in SDO. Thus, laïcité is a malleable ideology that can be adopted by individuals having contrasting motivations, as color blindness in the United States. Implications for the role of exact and conceptual replications in the development of a psychological science are discussed.

Bitcoin, gold and the US dollar – A replication and extension

Dyhrberg [2016. Bitcoin, gold and the dollar – A GARCH volatility analysis. Finance Research Letters 16, 85–92] analyzes the relationship between Bitcoin, gold and the US dollar and states that Bitcoin can be classified as something in between gold and the US dollar. This paper uses the same sample and econometric models to replicate the findings and demonstrates that exact replication is not possible and that alternative statistical methods provide more reliable, yet very different results. The findings based on the original sample and an extended sample period show that Bitcoin exhibits distinctively different return, volatility and correlation characteristics compared to other assets including gold and the US dollar.

Semi-static completeness and robust pricing by informed investors

We consider a continuous-time financial market that consists of securities available for dynamic trading, and securities only available for static trading. We work in a robust framework where a set of nondominated models is given. The concept of semi-static completeness is introduced: it corresponds to having exact replication by means of semi-static strategies. We show that semi-static completeness is equivalent to an extremality property, and give a characterization of the induced filtration structure. Furthermore, we consider investors with additional information and, for specific types of extra information, we characterize the models that are semi-statically complete for the informed investors. Finally, we provide some examples where robust pricing for informed and uninformed agents can be done over semi-statically complete models.

Digital light processing of ceramic components from polysiloxanes

Additive manufacturing using photocurable polymers is one method to answer the increased demand of ceramic structures with complicated morphology by fabricating ceramic parts with high resolution and good surface quality. We introduce here a new method to fabricate SiOC ceramic structures by utilizing a simple physical blend between two different preceramic polysiloxanes, one providing photosensitive acrylate groups while the other one a high ceramic yield. Different blend ratios have been realized and respectively optimized concerning the printing additives and setting times to fabricate exact replications of highly complex polysiloxane structures by Digital Light Processing. After pyrolysis, a uniform, homogenous shrinkage was observed yielding dense, pore- as well as crack-free SiOC ceramics. By adjusting the ratio between the different polysiloxanes, parameters such as the ceramic yield, shrinkage, chemical composition and resolution after pyrolysis could be tailored in a wide range of values.

Mental body transformation deficits in patients with chronic balance disorders.

Movements may be generated consistent with imagining one's own body transformed or "disembodied" to a new position. Based on this concept we hypothesized that patients with objective balance deficits (obj-BD) would have altered neural transformation processes executing own body transformation (OBT) with functional consequences on balance control. Also we examined whether feeling unstable due to dizziness only (DO), without an obj-BD, also lead to an impaired OBT. 32 patients with chronic dizziness were tested: 16 patients with obj-BD as determined by balance control during a sequence of stance and gait tasks, 16 patients with dizziness only (DO). Patients and 9 healthy controls (HCs) were asked to replicate roll trunk movements of an instructor in a life size video: first, with spontaneously copied (SPO) or "embodied" egocentric movements (lean when the instructor leans); second, with "disembodied" or "transformed" movements (OBT) with exact replication - lean left when the instructor leans left. Onset latency of trunk roll, rise time to peak roll angle (interval), roll velocity, and amplitude were measured. SPO movements were always mirror-imaged. OBT task latencies were significantly longer and intervals shorter than for SPO tasks (p < 0.03) for all groups. Obj-BD but not DO patients had more errors for the OBT task and, compared to HCs, had longer onset latencies (p < 0.05) and smaller velocities (p < 0.003) and amplitudes (p < 0.001) in both the SPO and OBT tasks. Measures of DO patients were not significantly different from those of HCs. Mental transformation (OBT) and SPO copying abilities are impaired in subjects with obj-BD and dizziness, but not with dizziness only. We conclude that processing the neuropsychological representation of the human body (body schema) slows when balance control is deficient.

Non‐animal models of wound healing in cutaneous repair: In silico, in vitro, ex vivo, and in vivo models of wounds and scars in human skin

Tissue repair models are essential to explore the pathogenesis of wound healing and scar formation, identify new drug targets/biomarkers and to test new therapeutics. However, no animal model is an exact replicate of the clinical situation in man as in addition to differences in the healing of animal skin; the response to novel therapeutics can be variable when compared to human skin. The aim of this review is to evaluate currently available non-animal wound repair models in human skin, including: in silico, in vitro, ex vivo, and in vivo. The appropriate use of these models is extremely relevant to wound-healing research as it enables improved understanding of the basic mechanisms present in the wound healing cascade and aid in discovering better means to regulate them for enhanced healing or prevention of abnormal scarring. The advantage of in silico models is that they can be used as a first in virtue screening tool to predict the effect of a drug/stimulus on cells/tissues and help plan experimental research/clinical trial studies but remain theoretical until validated. In vitro models allow direct quantitative examination of an effect on specific cell types alone without incorporating other tissue-matrix components, which limits their utility. Ex vivo models enable immediate and short-term evaluation of a particular effect on cells and its surrounding tissue components compared with in vivo models that provide direct analysis of a stimulus in the living human subject before/during/after exposure to a stimulus. Despite clear advantages, there remains a lack of standardisation in design, evaluation and follow-up, for acute/chronic wounds and scars in all models. In conclusion, ideal models of wound healing research are desirable and should mimic not only the structure but also the cellular and molecular interactions, of wound types in human skin. Future models may also include organ/skin-on-a-chip with potential application in wound healing research.

Reconsidering the expectancy disconfirmation model. Three experimental replications

ABSTRACTThe expectancy disconfirmation model (EDM) posits that disconfirmation (the difference between expectations and perceived performance) affects citizen satisfaction. Van Ryzin experimentally manipulated expectations and performance and found a direct effect of performance, but no disconfirmation. We performed: an exact replication; a conceptual replication with extreme manipulations; a conceptual replication that reversed the order of a performance and expectations manipulation. Study 1 and 2 reproduced original findings. In contrast, study 3 indicates that expectation cues are retrospectively used to anchor prior experiences of performance. As the rational assumptions underlying the EDM are increasingly challenged, we need a better understanding of how cognitive biases shape citizen satisfaction.

An Introduction to Zero-Coupon Risk-Free Bonds

This note introduces students to the basics of bonds and the time value of money through the simplest of financial contracts—the zero-coupon risk-free bond contract. The note covers the concepts of present value, yield to maturity, and bond pricing conventions. The note is appropriate as a companion for the Bond Trader simulation. A demo for this simulation is available at https://forio.com/simulate/darden/bond-trader-demo/. Excerpt UVA-F-1799 Rev. Sept. 7, 2018 An Introduction to Zero-Coupon Risk-Free Bonds One of the central principles of finance is that things that pay identical amounts have identical values. This principle is called the “Law of One Price.” The Law of One Price implies that one can value one financial contract by observing the value of another financial contract with similar expected return and risk. A related concept used in finance is that of “home cooking.” In financial markets one can “home cook” a version of a prevailing contract by combining existing financial products to create a “home-cooked” version. As such, the “home-cooked” version has the same value as, say, the “store-bought” version. As an example of this concept, suppose that you often buy chicken teriyaki sandwiches at a local food truck called the Big Kahuna. Your brother Rupert, an enterprising young man, has figured out how to exactly replicate the Big Kahuna chicken teriyaki sandwich. What is the value of Rupert's “home-cooked” exact replication of the Big Kahuna sandwich? Since the two sandwiches are identical, the sandwiches have the same value according to the Law of One Price. In finance, we will determine the value of a financial contract by observing the value of an identical replication of that contract that we can “cook up” by combining other contracts that are traded in security markets. In this note, we explore some first principles of pricing financial contracts using the Law of One Price. Although debt contracts go by many names, to simplify the discussion in this note we will use the term “bond” to denote any market-traded debt contract. Because the principles used to value simple contracts also apply to complicated contracts, we begin with the simplest of financial contracts—the zero-coupon risk-free bond contract. “Zero-coupon” bonds are simple promises to pay a certain amount at a specific point in time without any promise of making interest payments (or coupon payments) along the way. Zero-coupon bonds are simple IOUs. “Risk-free” bonds are promises that have certainty in the contracted payment. A risk-free promise of $ 1,000 is a sure promise that the payment will be made (there is no possibility of default or failure to make payment). . . .