Recall Of Events Research Articles

Causal and Chronological Relationships Predict Memory Organization for Nonlinear Narratives.

While recounting an experience, one can employ multiple strategies to transition from one part to the next. For instance, if the event was learned out of linear order, one can recall events according to the time they were learned (temporal), similar events (semantic), events occurring nearby in time (chronological), or events produced by the current event (causal). To disentangle the importance of these factors, we had participants watch the nonlinear narrative, Memento, under different task instructions and presentation orders. For each scene of the film, we also separately computed semantic and causal networks. We then contrasted the evidence for temporal, semantic, chronological, or causal strategies during recall. Critically, there was stronger evidence for the causal and chronological strategies than semantic or temporal strategies. Moreover, the causal and chronological strategies outperformed the temporal one even when we asked participants to recall the film in the presented order, underscoring the fundamental nature of causal structure in scaffolding understanding and organizing recall. Nevertheless, time still marginally predicted recall transitions, suggesting it operates as a weak signal in the presence of more salient forms of structure. In addition, semantic and causal network properties predicted scene memorability, including a stronger role for incoming causes to an event than its outgoing effects. In summary, these findings highlight the importance of accounting for complex, causal networks in knowledge building and memory.

The effect of social retelling on event recall

ABSTRACT Retelling an event in a social setting often means talking about it less factually than we might if trying to recall it as accurately as possible. These distortions that arise from socially oriented retellings could affect the ability to later recall the same event accurately. Does retelling a story in a social situation impair memory compared to not retelling it at all? Or could retrieving the memory, even with a socially oriented mindset, still improve memory? We explored social retelling's effect on memory in a two-session study. Participants heard two stories twice and, after a distractor task, retold the stories according to one of three randomly assigned conditions: social retelling (retell the stories as if talking to friends), accuracy retelling (retell the stories as accurately as possible), or no retelling. A day later, everyone retold the stories as accurately as possible. Participants in the accuracy retelling group included more specific details in their session two retellings than did the social retelling group, which included more specific details than the no retelling group. Elaborations in session two did not differ across groups. Findings suggest retelling a story in a social situation benefits memory, though not as much as retelling a story accurately does.

Performance of somatic structural variant calling in lung cancer using Oxford Nanopore sequencing technology

BackgroundLung cancer is a heterogeneous disease and the primary cause of cancer-related mortality worldwide. Somatic mutations, including large structural variants, are important biomarkers in lung cancer for selecting targeted therapy. Genomic studies in lung cancer have been conducted using short-read sequencing. Emerging long-read sequencing technologies are a promising alternative to study somatic structural variants, however there is no current consensus on how to process data and call somatic events. In this study, we preformed whole genome sequencing of lung cancer and matched non-tumour samples using long and short read sequencing to comprehensively benchmark three sequence aligners and seven structural variant callers comprised of generic callers (SVIM, Sniffles2, DELLY in generic mode and cuteSV) and somatic callers (Severus, SAVANA, nanomonsv and DELLY in somatic modes).ResultsDifferent combinations of aligners and variant callers influenced somatic structural variant detection. The choice of caller had a significant influence on somatic structural variant detection in terms of variant type, size, sensitivity, and accuracy. The performance of each variant caller was assessed by comparing to somatic structural variants identified by short-read sequencing. When compared to somatic structural variants detected with short-read sequencing, more events were detected with long-read sequencing. The mean recall of somatic variant events identified by long-read sequencing was higher for the somatic callers (72%) than generic callers (53%). Among the somatic callers when using the minimap2 aligner, SAVANA and Severus achieved the highest recall at 79.5% and 79.25% respectively, followed by nanomonsv with a recall of 72.5%.ConclusionLong-read sequencing can identify somatic structural variants in clincal samples. The longer reads have the potential to improve our understanding of cancer development and inform personalized cancer treatment.

The influence of clinical practice video on learning conversations in postgraduate medical education: A scoping review

Introduction: Studies of learning conversations in medical education suggest these interactions can be supervisor driven, monologic and may involve poor recall of events. Educators often use camouflaged comments to avoid upsetting learners, which can interfere with meaning making. Using video of clinical practice within learning conversations could address some of these potential limitations. Despite educators using video of clinical practice in learning conversations for decades, we could find no synthesis of empirical studies to provide insight into the influence of video in learning conversations. Therefore, we conducted a scoping review to answer the question “How does video of clinical practice influence learning conversations in post-graduate medical education?” Methods: We employed a scoping review methodology. MEDLINE, Embase, PsycINFO and ERIC databases were searched for articles from 1 January 2010 to 1 January 2022. Major inclusion criteria were postgraduate medical learners and video of clinical practice that was used in a learning conversation. The qualitative data relating to video’s influence on learning conversations were synthesised and thematically analysed. Results: Five articles were included in the synthesis. We generated four themes from the qualitative data about the influence of video on the learning conversation. Video: (1) captures performance data that can be co-analysed, (2) enables the learning conversation to take place in a different environment, (3) changes the teaching approaches of educators and (4) may promote learner agency and voice. Conclusion: Video may influence learning conversations, and video’s influence is likely entangled with the educational design associated with its use. No study directly addressed the phenomenon of how video influences learning conversations, and further study is required in this area.

Class I Recalls of Cardiovascular Devices Between 2013 and 2022 : A Cross-Sectional Analysis.

Cardiovascular devices account for one third of all Class I recalls, the U.S. Food and Drug Administration's (FDA) most severe designation, indicating a reasonable probability of "serious adverse health consequences or death." Understanding recalls and their causes is important for patient safety. To characterize Class I recalls of cardiovascular devices and the clinical evidence supporting authorization. In this cross-sectional study, cardiovascular device recalls from 1 January 2013 through 31 December 2022 were identified using the FDA's annual log. Information about devices was extracted from publicly available FDA decision summaries. The FDA Medical Device Recalls database. Cardiovascular devices with Class I recalls. Recalls were characterized by their causes and scope. Devices were characterized by their regulatory history (product code, special designations) and clinical evidence (premarket testing, postmarket surveillance). Clinical studies were analyzed for quality, including end point selection (clinical vs. surrogate, use of composites). From 2013 to 2022, there were 137 Class I recall events affecting 157 unique cardiovascular devices, of which 112 (71.3%) were moderate-risk 510(k) devices and 45 (28.7%) were high-risk premarket approval (PMA) devices. Recalls affected a median of 7649 units (IQR, 953 to 28 446) and were most commonly attributed to device design (43 [31.4%]). Forty-two (26.8%) devices had multiple Class I recalls. Thirty (19.1%) devices underwent premarket clinical testing (7 [6.2%] 510(k) devices, 17 [85.0%] PMA devices, and 6 [24.0%] PMA supplement devices). Most studies used surrogate (27 [79.4%]) and composite (24 [70.6%]) measures as primary end points. Twenty-two (48.9%) PMA devices had required postapproval studies, with 14 reporting delays. No 510(k) devices were subject to postmarket surveillance. Details about clinical testing may be missing from FDA summaries. Cardiovascular devices with Class I recalls were infrequently subjected to premarket or postmarket testing, with recalls affecting thousands of patients annually. None.

B - 35 Recall of the Injury Event in Moderate–Severe Traumatic Brain Injury

Abstract Objective Autobiographical recall can be impoverished in Traumatic Brain Injury (TBI). We explored whether the recall of the TBI event was unique to this trend since the event is both self-defining and traumatic. Methods We recruited 30 non-injured comparison participants (NC) and 30 participants in the chronic phase of a moderate–severe TBI from the Brain Injury Patient Registry at Vanderbilt University Medical Center. Participants in the TBI group recalled their TBI event and a self-selected event from 0–5 years before the TBI. The NC group recalled a self-selected event that matched the pre-injury’s temporal distance. We used the Autobiographical Interview scoring system to test whether events differed in the amount and type of details. Results Compared to the pre-injury event, the injury event had a higher number of episodic-like, p = 0.002, and external details (e.g., repetition and meta-comments), p = 0.011. The injury and pre-injury events had a similar proportion of episodic-like details (relative to all details), p = 0.295, indicating events were similarly supplemented with extraneous/inferential information. Further, the pre-injury event of the TBI group had a smaller number of episodic-like details, p < 0.001, and a lower proportion of episodic-like details, p = 0.002, than the events from the NC group. Conclusion Whereas the recall of injury events may be unique due to their higher number of episodic-like details, they were also similar to general autobiographical memory recall in the preponderance of supplementary details. A confluence of factors, like personal relevance, compromised encoding due to loss of consciousness at the time of injury, and general difficulties in retrieval, may explain the findings.

When Vulnerable Narcissists Take the Lead: The Role of Internal Attribution of Failure and Shame for Abusive Supervision

AbstractResearch to date provides only limited insights into the processes of abusive supervision, a form of unethical leadership. Leaders’ vulnerable narcissism is important to consider, as, according to the trifurcated model of narcissism, it combines entitlement with antagonism, which likely triggers cognitive and affective processes that link leaders’ vulnerable narcissism and abusive supervision. Building on conceptualizations of aggression as a self-regulatory strategy, we investigated the role of internal attribution of failure and shame in the relationship between leaders’ vulnerable narcissism and abusive supervision. We found across three empirical studies with supervisory samples from Germany and the United Kingdom (UK) that vulnerable narcissism related positively to abusive supervision (intentions), and supplementary analyses illustrated that leaders’ vulnerable (rather than grandiose) narcissism was the main driver. Study 1 (N = 320) provided correlational evidence of the vulnerable narcissism-abusive supervision relationship and for the mediating role of the general proneness to make internal attributions of failure (i.e., attribution style). Two experimental studies (N = 326 and N = 292) with a manipulation-of-mediator design and an event recall task supported the causality and momentary triggers of the internal attribution of failure. Only Study 2 pointed to shame as a serial mediator, and we address possible reasons for the differences between studies. We discuss implications for future studies of leaders’ vulnerable narcissism as well as ethical organizational practices.

Autobiographical memory phenomenology in transgender and cisgender individuals

ABSTRACT Transgender individuals face challenges to identity as they transition from their sex assigned at birth to their affirmed gender. Memories may support a sense of self through the recall of events with more phenomenological detail than others, making them feel closer to the current self. Autobiographical memories of 90 transgender and 90 cisgender adults were compared on self-reported memory phenomenology. Memory phenomenology was more variable in transgender individuals, with a larger difference between phenomenological ratings of recent and distant memories. Memory phenomenology specifically varied in relation to the timing of coming out to a parent. High points reported after this time were rated with higher phenomenological quality and these ratings were linked to positive well-being. Results affirm the relevance of phenomenological continuity to the identity of transgender individuals, suggesting that events from before coming out are recalled with less phenomenological quality than events after coming out.

Attention to event segmentation improves memory in young adults: A lifespan study.

People spontaneously segment an observed everyday activity into discrete, meaningful events, but segmentation can be modified by task goals. Asking young adults to attend to event segmentation while watching movies of everyday actions improved their memory up to 1 month later (Flores et al., 2017). Does attending to event segmentation improve memory across the lifespan? Participants between the ages of 20 and 79 watched movies of actors performing everyday activities while intentionally encoding them for a recall and a recognition memory test 1 week (Experiment 1) or 1 month (Experiment 2) later. In addition to intentionally encoding the movies, half of the participants segmented the movies into fine-grained events. Young adults who segmented recalled more words in their recall responses than those who intentionally encoded 1 week and 1 month later. Middle-aged adults benefited from the intervention after a 1-week delay but not after a 1-month delay. Older adults over the age of 70 did not benefit from attending to segmentation. Of those who segmented, young and older adults showed similar agreement about the locations of event boundaries. Together, the results suggest that older adults are less able, compared to young adults, to maintain or retrieve well-encoded event memories after a delay. In addition, individual differences in segmentation agreement predicted memory up to 1 month later, regardless of age. These results suggest a practical and easy-to-implement intervention for improving recall of everyday events in young and middle-aged adults that is ineffective in older adults. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Foreign identity and organizational crises: Evidence in the U.S. automobile industry

Multinational corporations (MNCs) adeptly manage Liabilities of Foreignness (LOF) and Assets of Foreignness (AOF) to their advantage, and central to this endeavor is the strategic management of their foreign identity. Our research identifies a critical context where foreign identity remains a liability: organizational crises. Drawing on organizational identity and legitimation process theories, we contend that foreign firms face greater legitimacy losses compared to domestic firms during crises due to magnified foreign identity and differences in legitimacy standards. Furthermore, a crisis in one foreign firm can trigger stronger negative spillover effects on other foreign firms than on domestic firms. We test our theory through an analysis of US automobile recall events, demonstrating significant legitimacy impacts for foreign firms. Our findings illuminate the complex dynamics of foreign identity management, offering new insights into the persistent challenges of LOF during times of crisis.

Storytelling changes the content and perceived value of event memories

Memories are not only stored for personal recall, but also to communicate knowledge to others in service of adaptive decision-making. Prior research shows that goals to share information can change which content is communicated in memory as well as the linguistic style embedded in this communication. Yet, little is known as to how communication-related alterations in memory narration drive differences of value processing in listeners. Here, we test how memory communication alters multi-featural recall for complex events and the downstream consequence on value estimations in naïve listeners. Participants recalled a memory of playing an exploratory videogame at a 24-h delay under instructions to either share (i.e., social condition) or recall (i.e., control condition) their memory. Sharing goals systematically altered the content and linguistic style of recall, such that narrators from the social condition were biased towards recall of non-episodic details and communicated their memories with more clout, less formality, and less authenticity. Across two independent samples of naïve listeners, these features differentially influenced value estimations of the video game. We found that greater clout was associated with greater enjoyment while listening to memories (hedonic value), and that greater inclusion of non-episodic details resulted in greater willingness to purchase the video game (motivational drive). These findings indicate that sharing an experience as a story can change the content and linguistic tone of memory recall, which in turn shape perceived value in naïve listeners.

The continuing challenge of drug recalls: Insights from a ten-year FDA data analysis

In this study we analyzed drug recall data from the U.S. Food and Drug Administration (FDA) over the period 2012–2023. We identified trends in the number of recalls initiated annually and their underlying causes. On average, 330 drug recalls are initiated each year, showing an overall increasing trend. The average duration of a recall, from initiation to termination date, was 1.3 years and each recall involved on average 400 000 product units, implying considerable resource demands and consequences for all stakeholders. The most frequent cause of these recalls was found to be impurities and contaminants (37 %), followed by control (28 %) and labeling/packaging (19 %) issues. Recalls of medicines causing serious health problems or death (class I), accounted for 14 % of the recall events. Continuous evaluation of recalls is expected to reduce their number, mitigate their impact on the healthcare system and improve drug safety.

Pride in foreign language learning: a conceptual framework and empirical evidence

ABSTRACT Previous studies have found that pride is a frequent and important emotion in achievement contexts although it is under-researched in the second/foreign language (FL) context. Therefore, the aim of this research was to explore pride in the context of FL learning. For this purpose, we proposed a conceptual model of FL pride, drawing on previous theoretical frameworks, which distinguishes four types of pride: self-based, social comparison-based, praise-based, and help-based. Then, to test this model, we conducted two studies. In Study 1, we asked participants to recall events that they felt pride during the FL process. In Study 2, we developed and validated foreign language pride scale (FLPS). Results of confirmatory factor analysis indicated that FL pride is best represented by a higher-order model. We further investigated its criterion-related validity by examining the relations between FL pride and theoretically relevant constructs and found that it is related to several motivational, emotional, and outcome measures.

Introducing ICBe: an event extraction dataset from narratives about international crises

Abstract How do international crises unfold? We conceptualize international relations as a strategic chess game between adversaries and develop a systematic way to measure pieces, moves, and gambits accurately and consistently over a hundred years of history. We introduce a new ontology and dataset of international events called ICBe based on a very high-quality corpus of narratives from the International Crisis Behavior (ICB) Project. We demonstrate that ICBe has higher coverage, recall, and precision than existing state of the art datasets and conduct two detailed case studies of the Cuban Missile Crisis (1962) and the Crimea-Donbas Crisis (2014). We further introduce two new event visualizations (event iconography and crisis maps), an automated benchmark for measuring event recall using natural language processing (synthetic narratives), and an ontology reconstruction task for objectively measuring event precision. We make the data, supplementary appendix, replication material, and visualizations of every historical episode available at a companion website crisisevents.org.

Mothers' negative focus during memory‐sharing conversations is linked to negative interpretation and memory biases in young children

AbstractParent‐guided reminiscing helps children learn how to interpret and recollect personal experiences. These interpretive abilities are important because many experiences are ambiguous, and a tendency toward negative interpretation is associated with emotional disorders. Here, we explore whether naturally‐occurring variations in parent‐guided reminiscing are associated with children's interpretation and recall of novel ambiguous events. Mothers and their children (aged 5–6 years) reminisced about three shared negative events. Next, children were read several stories that described ambiguous social situations and were asked to invent endings that involved making an inference about motives of others in the stories. Later, children were asked questions to elicit story recall. Mothers who used more negative terms during reminiscing had children who were more likely to invent negative story endings and distort story recall negatively. Thus, mothers who frame memory‐sharing conversations with children negatively might put them at risk for developing negative interpretation and memory biases.

Transitional Care in Patients With Hirschsprung Disease: Those Left Behind.

The long-term effects of Hirschsprung disease are clinically variable. An improved understanding of challenges patients may face as adults can help inform transitional care management. To explore the outcomes and transitional care experiences in adult patients with Hirschsprung. Cohort study. Single center. All patients treated for Hirschsprung between 1977 and 2001 (aged older than 18 years at the time of survey distribution in July 2018-2019). Eligible patients were sent validated multidomain surveys and qualitative questions regarding their transitional care. Status of transitional care, bowel function, and quality-of-life assessment. Qualitative analysis of transitional care experience. Of 139 patients, 20 had received transition care (10 had at least 1 visit but had been discharged and 10 were receiving ongoing follow-up). These patients had inferior bowel function and quality-of-life scores at follow-up. Twenty-three patients (17%) had issues with soiling at the time of discharge, and 7 patients received transitional care. Of these 23 patients, 9 (39%) had a normal Bowel Function Score (17 or more), 5 (22%) had a poor score (less than 12), and 1 had since had a stoma formation. Eighteen patients (13%) had active moderate-severe issues related to bowel function, only 5 had been transitioned, and just 2 remained under ongoing care. Importantly, when these patients were discharged from our pediatric center, at a median age of 14 (interquartile range, 12-16) years, 10 of 17 patients had no perceptible bowel issues, suggesting a worsening of function after discharge. The retrospective design and reliance on clinical notes to gather information on discharge status as well as patient recall of events. There remains a small but significant proportion of Hirschsprung patients for whom bowel function either remains or becomes a major burden. These results support a need to better stratify patients requiring transitional care and ensure a clear route to care if their status changes after discharge. See Video Abstract . ANTECEDENTES:Los efectos a largo plazo de la enfermedad de Hirschsprung son clínicamente variables. Una mejor comprensión de los desafíos que los pacientes pueden enfrentar cuando sean adultos puede ayudar a informar la gestión de la atención de transición.OBJETIVO:Explorar los resultados y las experiencias de atención de transición en pacientes adultos con Hirschsprung.DISEÑO:Estudio de cohorte.AJUSTE:Unico centro.PACIENTES:Todos los pacientes tratados por Hirschsprung 1977-2001 (edad >18 años en el momento de la encuesta, Julio de 2018-2019). A los pacientes elegibles se les enviaron encuestas multidominio validadas, así como preguntas cualitativas sobre su atención de transición.PRINCIPALES MEDIDAS DE RESULTADOS:Estado de la atención de transición, función intestinal y evaluación de la calidad de vida. Análisis cualitativo de la experiencia de cuidados transicionales.RESULTADOS:De 139 pacientes, 20 habían recibido atención de transición (10 tuvieron al menos una visita pero habían sido dados de alta y 10 estaban recibiendo seguimiento continuo). Estos pacientes tenían puntuaciones inferiores de función intestinal y calidad de vida en el seguimiento. Veintitrés (17%) pacientes tuvieron problemas para ensuciarse en el momento del alta y 7 recibieron atención de transición. De estos, 9/23 (39%) tenían una puntuación de función intestinal normal (≥17), 5/23 (22%) tenían una puntuación baja (<12) y un paciente había tenido desde entonces una formación de estoma. Dieciocho (13%) pacientes tenían problemas activos de moderados a graves relacionados con la función intestinal, solo cinco habían realizado la transición y solo 2 permanecían bajo atención continua. Es importante destacar que cuando estos pacientes fueron dados de alta de nuestro centro pediátrico, a una edad promedio de 14 [RIQ 12-16] años, 10/17 no tenían problemas intestinales perceptibles, lo que sugiere un empeoramiento de la función después del alta.LIMITACIONES:El diseño retrospectivo y la dependencia de notas clínicas para recopilar información sobre el estado del alta, así como el recuerdo de los eventos por parte del paciente.CONCLUSIÓN:Sigue existiendo una proporción pequeña pero significativa de pacientes con Hirschsprung para quienes la función intestinal permanece o se convierte en una carga importante. Estos resultados respaldan la necesidad de estratificar mejor a los pacientes que requieren atención de transición y garantizar una ruta clara hacia la atención si su estado cambia después del alta. ( Traducción-Dr. Yesenia Rojas-Khalil ).

Drawing on memory: A meta‐analytic review

AbstractDrawing is commonly used to facilitate event recall in eyewitness and therapeutic settings. Building on Derksen and Connolly’s (2022) review, we meta‐analytically examined how drawing affects memory relative to purely verbal methods of communication (e.g. ‘talk only’ interviews). Database searches identified 36 randomised controlled trials of the effect of drawing‐based interventions on event memory (N = 2013). Our memory outcome measures were amount and accuracy of information reported, errors and confabulations. Random‐effects analysis indicated drawing was favoured relative to verbal controls across these four outcomes. Drawing enhanced the amount (g = 0.63, p &lt; .001) and accuracy (g = 0.29, p = .014) of information reported, but did not reduce errors (g = 0.05, p = .633) or confabulations (g = 0.22, p = .488) relative to control. The memory benefits of drawing were not moderated by age (children vs. adults), event type (autobiographical vs. live/staged vs. video), control type (visual‐active vs. verbal‐only) or task timing (immediate vs. delay). Two potential moderators could not be analysed due to the paucity of studies: event focus (trauma‐related vs. non‐trauma‐related) and drawing focus (event‐focused vs. non‐event‐focused). Our meta‐analysis indicates that drawing is a valuable facilitator of event recall relative to traditional methods of communication. However, our review also highlights the need for more trauma‐specific studies. We address and offer practical recommendations for future studies to address potential risks that may result from using drawing in applied settings.

Unlocking the past: efficacy of guided self-compassion and benefit-focused online interventions for managing negative personal memories

ABSTRACT Positive reappraisal strategies have been found to reduce negative affect following the recall of negative personal events. This study examined the restorative effect of two mood-repair instructions (self-compassion vs benefit-focused reappraisal) and a control condition with no instructions following a negative Mood Induction Procedure by using the guided recall of a negative autobiographical event. A total of 112 university students participated in the online study (81% women, Mage: 21.0 years). Immediately following the negative memory recall, participants were randomised to each condition [(self-compassion: n = 36, benefit-focused: n = 39) or a control condition (n = 37)]. Repeated measures ANOVAs 3 (Repair condition) × 3 (Time of mood assessment: pre-recall, post-recall, post-regulation) showed that, as expected, negative mood (sadness, shame, and guilt) worsened significantly after the guided recall in all groups (p < .001). After the mood-repair intervention, participants in the self-compassion and benefit-focused conditions showed a significant reduction in negative mood (p < .019), while such improvement was not observed in the control group. Self-compassion and benefit-focused reappraisal functioned similarly as mood repair strategies after experiencing negative affect induced by the recall of negative personal memories. Implications in the context of autobiographical memory biases are discussed.

OneTrace: Improving Event Recall and Coordination With Cross-Application Interaction Histories

To coordinate and understand past actions in a collaborative activity, co-workers typically access shared artifacts and the interaction histories provided by their tools. We interviewed 12 knowledge workers who collaborate on shared text documents. We found that the scattering of historical data across collaborative and personal environments and the lack of compatibility between histories hinder coordination and event recall. To explore the design of cross-application history tools, we created OneTrace, a proof-of-concept system for sharing histories amongst applications and users based on a unified structure for representing interaction traces. We then introduce TracePicker, a tool that lets users cluster traces to contextualize past actions recorded by OneTrace. We evaluated TracePicker using a questionnaire- and scenario-based observation study. Results show that participants found the system helpful for communicating, understanding and contextualizing historical data. We conclude that designing cross-application histories such as OneTrace supports coordination and event recall.

Evaluation of qCON and qNOX indices in pediatric surgery under general anesthesia.

The objective of the study was to evaluate the performances of qCON and qNOX indices in pediatric populations undergoing surgery under general anesthesia (GA), focusing on the induction and recovery periods. Both the indices are derived from electroencephalogram (EEG) and implemented in the CONOX monitor (Fresenius Kabi, Germany). After approval of the institutional ethics committee, this prospective observational study was conducted in pediatric patients of either sex in the age group of 1-12 years belonging to the American Society of Anesthesiology (ASA) grade I and II undergoing elective surgery under GA. Anesthetic technique was GA with or without regional analgesia (RA). All patients underwent inhalation induction and maintenance using sevoflurane. Patients were monitored with the use of a CONOX monitoring system (Fresenius Kabi, Germany), connected via a set of electrodes placed over the forehead. qCON and qNOX scores were recorded during awake (on operating table premedicated with oral midazolam 0.5 mg/kg), at induction, at loss of eyelash reflex, intubation/laryngeal mask airway (LMA) insertion, before and after regional anesthesia, surgical incision, at cessation of anesthesia, emergence, extubation, and eye-opening. Registered results were also analyzed compared with the minimum alveolar concentration of sevoflurane (MAC). A total of 46 pediatric patients were enrolled in the study with a mean age of 5.6 years. All the patients were either ASA I or II. There was a simultaneous fall and rise of qCON and qNOX upon induction and recovery, respectively. There was a rise in qNOX with surgical incision irrespective of RA. However, there was a greater rise in qNOX following surgical incision in those who did not receive RA (P = 0.33) Also both qCON (P = 0.06) and qNOX (P = 0.41) were poorly correlated with MAC values of sevoflurane during GA in the pediatric population. Both qCON and qNOX values change predictably with changes in the conscious level and with different noxious stimuli. Further studies are required to confirm the findings taking into account the postoperative assessment of delirium and recall of intraoperative events.