Chronic crack of the lip has a high prevalence among young people in subarctic climates. The disease relapses and remissions. Linear cracks on the lips cause pain, discomfort, defects, aesthetics, cracks are completely constantly observed without complex treatment and prevention during exposure to adverse environmental conditions. The meteorological factor is a trigger mechanism for the development of chronic recurrent lip cracks in the subarctic climate. Cold wind and high sweetness destabilize the barrier function of the lip epithelium, reduce the activity of intercellular lipids. The study involved 68 male patients aged 18 to 28 years with an established diagnosis of chronic recurrent lip crack. In patients, adverse meteorological conditions were carriers of etiological diseases according to the anamnesis. At the primary medical appointment, the doctor treated chronic cracks with 0.05% chlorhexidine bigluconate, took an anamnesis, and took a complete blood count. Patients were divided into 3 groups of average manifestations of diseases (defect size, duration and nature of the manifestation). Within 14 days, patients had to adhere to the local therapy plan: group 1 used a cream based on 0.1% mometasone for 7 days, cocoa butter 3 times a day for the next 7 days, group 2 - the use of 20% propolis ointment 2-3 times a day, group 3 - local sea buckthorn oil 5 times a day. All patients were given recommendations and prescribed vitamin therapy for 2 months: AEvit and Combilipen. The subjects were tested to determine the interest in treatment on the 7th day. We evaluated the results of treatment on days 7, 14 and 30. Based on the results of the study, we concluded that, regardless of the interest in treatment, the best results were shown by treatment according to the group 1 scheme with the use of glucocorticoids. The rest of the study participants had results ranging from complete epithelialization and remission to no sign of improvement, depending on the level of interest in treatment. The treatment of a chronic lip crack requires an individual and comprehensive approach and the patient's obligatory interest in treatment. Patients should definitely use lipids as part of hygienic lipsticks during the remission period. This local prophylaxis helps restore the lipid matrix of the stratum corneum and maintain the lipid barrier of the red border of the lips from the effects of adverse meteorological factors of the subarctic climate.