The review summarizes the results of studying the problem of environmental mercury pollution and associated risks to public health. Toxicological and hygienic studies include an analysis of the main sources of heavy metal emissions, ways of their distribution in the environment and biological effects on humans. The basis of anthropogenic pollution was shown to include the following: artisanal mining, coal burning and non-ferrous metal production. Out of the places of emissions metal is distributed with atmospheric air over long distances, as evidenced by the results of monitoring studies conducted in the Arctic and Antarctica. Pollution of water is extremely dangerous for human health, since it is proven that the main source of mercury intake is associated with the consumption of fish and seafood. In the soil horizon the toxicant is localized mainly in arable layers but in places where mercury-containing waste is stored, the metal can migrate to a depth of 18 m or more. Analysis of the mechanisms of adsorption, distribution, metabolism and excretion allows concluding: the greatest threat to health are metal-organic forms (methyl-and dimethyl-mercury), which is associated with the high lipophilicity of these compounds. On the example of Minamata disease there is given a description of the characteristic signs of mercury intoxication among which the Central nervous system is the leading one. There are presented the results of the research of biological effects of low metal concentrations and modern means of preventing negative impact on human health. Contact of the General population in production and everyday life determines the necessity for a comprehensive study and coverage of the effects associated with exposure of toxic mercury compounds.