Efficacy Of Plant Extracts Research Articles (Page 1)

Introduction: The study is aimed to assess the plant bioactive compounds of Selaginella plana in treating diabetic neuropathy. The plant components were assessed using ethanol as the solvent. Methods: A phytochemical screening was conducted to ascertain the existence of secondary metabolites in the plant extracts. The efficacy of plant extract against neuropathic pain was determined using plantar test and Von Frey filament stimulation. Biochemical tests were performed to determine the level of SGOT, SGPT, ALP, HDL, CHO, LDL, Creatinine and Urea. The percentage yield of ethanol and aqueous extract was 19.22 g and 15.76 g, respectively. Results: The ethanolic extract showed presence of most of the phytoconstituents like alkaloids, flavonoids, carbohydrates, tannins, phytosterols, glycosides, proteins, and gum. Thus, ethanolic extract was used for further studies. In contrast to disease induced rats, rats given the extract chronically had a considerably shorter hind paw withdrawal latency. In STZ-induced diabetic rats, the mechanical withdrawal threshold dramatically reduced mechanical allodynia after 7 days by a dose of 400 mg/kg. Conclusion: The major findings of the study demonstrated that STZ-induced diabetic rats administered leaf extract had reduced neuropathic pain. It can be concluded that S. plana may be used as an alternative drug in the treatment of diabetic neuropathy.

Efficacy of plant extracts as green indicators in acid-base titrimetric analysis: Perspective towards green chemistry

Efficacy of plant extracts in enhancing growth and molting of crab (Scylla serrata) in a traditional pond system

Background: Mycotoxins, which are secondary metabolites produced by fungi, are prevalent in animal feed and pose a serious risk to the healthy growth of livestock and poultry. Methods: This review aims to conclude current knowledge on the detrimental effects of mycotoxins on animal health and to demonstrate the potential of plant extracts as a means to counteract mycotoxin toxicity in feed. A systematic review of the literature was conducted to identify studies on the impact of mycotoxins on livestock and poultry health, as well as research into the use of plant extracts as feed additives to mitigate mycotoxin effects. Studies were selected based on their relevance to the topic, and data were extracted regarding the mechanisms of action and the efficacy of plant extracts. Results: Excessive mycotoxins in feed can lead to reduced appetite, impaired digestion, and general health issues in animals, resulting in decreased food intake, slowed weight gain, and instances of acute poisoning. Plant extracts with antioxidant, anti-inflammatory, and anti-mutagenic properties have shown the potential to improve production efficiency and reduce the toxic effects of mycotoxins. Conclusion: This comprehensive review not only consolidates the well-documented adverse effects of mycotoxins on animal health but also introduces a novel perspective by highlighting the potential of plant extracts as a promising and natural solution to counteract mycotoxin toxicity.

Abstract This study aims to assess the suppressive effect of plant crude extracts, bio-, and mineral fertilizers, plant-animal origin compost, and vermicompost for controlling potato bacterial wilt and soft diseases in in-vitro and in-vivo pots experiments. Nine plant crude extracts were screened in-vitro for their antibacterial effectiveness against Ralstonia solanacearum, Pectobacterium carotovorum, and Pectobacterium atrosepticum. Ethanolic and water crude extracts from peels and leaves of Punicum granatum L. and Eucalyptus camaldulensis Dehnh respectively, showed the most growth inhibition against the three tested bacteria. In-vivo assessment, the peels ethanolic and water crude extract for P. granatum L. were the most effective treatments that exhibited a 91% and 89% decrease in the disease severity, area under disease progress curve of R. solanacearum wilt disease, population count, and enhanced the potato growth parameters, triterpenoids, and higher potato yield compared to other assessed mineral and organic fertilizers. In another in-planta experiment, treating potato tubers with these plant extracts significantly suppressed the maceration symptoms on the tubers, pre-inoculated by either P. carotovorum or P. atrosepticum with a treatment efficiency (TE) of 100% for each, except for the water extract of E. camaldulensis Dehnh that showed 22% of efficiency as compared to untreated potato tubers. Phytochemical characterization and Gas Chromatography-Mass Spectrometry (GC-MS) revealed the presence of phenols, tannins, and flavonoids that have antimicrobial activity in both extracts. These treatments are recommended to be applied individually or as an effective component of integrated pest management program to enhance potato tolerance against bacterial pathogens during the growing season and storage.

Synergistic antimicrobial strategies: Efficacy of plant extracts and silver nanoparticles against bacterial pathogens in Penaeus monodon

This research aimed to find indigenous plants and suitable solvents to extract substances with the capacity to suppress the immature stages of house fly populations in animal farms and urban areas. Seven native Thai plants were tested: Alstonia scholaris (L.) R.Br., Murraya paniculata (L.) Jack, Citrus aurantium L., Colocasia esculenta (L.) Schott, Limnophila aromatica (Lam.) Merr., Persicaria odorata (Lour.), and Manihot esculenta Crantz. Solvents with different polarities were used in series (hexane, ethyl acetate, acetone, ethanol, and water) to extract the active compounds from the plant tissues. The effects of extracts on immature stage were assessed separately in vitro using a completely randomized design with 5 replicates. The effects of each plant extract on the house fly stages varied depending on the solvent utilized. Extracts with high polarity solvents (ethanol and acetone) showed strong ovicidal activity but for larval and pupal stages, hexane, a low polarity solvent, demonstrated significant larvicidal and pupicidal activity. Acetone and ethanol solvents of P. odorata and L. aromatica caused notable mortality rate for the egg stage. Hexane extracts of M. paniculata and both hexane and ethyl acetate extracts of C. aurantium induced the highest percentage of larval mortality. Even if other plant extracts have less of an impact on the mortality of house fly eggs or larvae, they have an impact on the growth and development. The results showed that most plant extracts based on various solvents caused considerable mortality in house fly pupa. In this study, the hatching percentage of adult females was lower than the adult males after specific plant extracts were applied throughout the larval and pupal phases. High-efficiency plant extracts' LC50 and LC90 values for house fly immature stages were calculated. The acetone extract of P. odorata during the egg stage had LC50 and LC90 values of 7.816 and 31.117 mg/mL, respectively. At the larval stage, M. paniculata's hexane extract had concentrations of 4.865 and 22.284 mg/mL, while C. aurantium's ethly acetate extract had concentrations of 26.424 and 61.801 mg/mL. Significant active chemicals discovered by GC-MS analysis were included bioactive substances with insecticidal properties, including flavonoids, alkanes, coumarins, etc., were identified by GC-MS analysis.

Efficacy of plant extracts and Calotropis dust on the feeding deterrence of the blister beetle, Mylabris pustulata Thunberg (Coleoptera: Meloidae)

Abstract Rust-free building materials are crucial for ensuring the durability and structural stability of constructions. Corrosion, a widespread issue affecting metals like steel, copper, and concrete, can be effectively managed with the help of corrosion inhibitors. One effective method for corrosion inhibition involves the application of corrosion-inhibiting coatings, which form resilient and tightly adherent films on metal surfaces. Flavonoids, renowned for their diverse biological activities, demonstrate significant anticorrosive properties. They contain beneficial compounds such as antioxidants and chelating agents. The efficacy of plant extracts as corrosion inhibitors is influenced by their organic constituents, particularly phenols and flavonoids. Flavonoids act by creating a protective film that serves as a barrier, shielding the metal surface from corrosive agents and limiting their access to the metal. This contributes to the prevention of corrosion. The integration of flavonoids into building materials has the potential to transform corrosion prevention practices, leading to improved durability, reduced maintenance costs, and a more environmentally friendly built environment. This article explores the promising prospects of flavonoids as an innovative and sustainable approach to corrosion prevention in building materials. Additionally, it aims to stimulate further research endeavors, fostering the development of effective and eco-friendly corrosion protection strategies for the construction industry.

Semen Cannabis and Oleum Hyperici: Antileishmanial activity against Leishmania tropica promastigotes and intracellular amastigotes

Abstract Background: Chronic low back pain (CLBP) impacts quality of life and healthcare reliance. Objectives: We systematically reviewed randomized controlled trials (RCTs) on the use of plant extracts to treat CLBP according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Methods: Four databases (i.e., PubMed, Scopus, Web of Science, and The Cochrane Library) were searched for published studies. We searched databases up to July 2024. Seven RCTs were analyzed. The study has been registered in PROSPERO (number: CRD 42024570674). Results: Plant extracts alone or combined with massage significantly reduced pain, particularly when applied to multiple meridian points. Conclusion: Plant extracts are a promising nonpharmacological treatment option for CLBP. One potential mechanism is through their interaction with multiple meridian pathways, which may enhance pain relief. This possible relationship between meridian involvement and therapeutic efficacy warrants further investigation to better understand the long-term benefits and underlying mechanisms of plant extract therapy.

Evaluation and efficacy of plant extracts in eradicating medically important mosquitoes: a review

Introduction: Bletilla Striata (Thunb. ex A. Murray) Rchb. f.) Is a native herb of the orchidaceae family. Modern pharmacological activity studies have shown that Bletilla striata mainly has pharmacological activities such as promoting blood circulation and hemostasis, promoting wound healing anticancer, anti-tumor disease-resistant pathogenic microorganisms, protecting mucosa, anti-ulcer, whitening and anti-oxygen, anti-aging, and immune regulation, which have been widely recognized and applied. Research on the efficacy of plant extracts mainly adopts in vitro testing methods, such as cell experiment and 3D skin model experiment. Objective: To evaluate the soothing effect of Bletilla striata extracton UVB-stimulated keratinocytes (HaCaT) and its barrier repair efficacy in Skinovo-Epi skin model. Methods: The soothing and barrier repairing effects of Bletilla striata extract were studied in vitro. The cytotoxicity of the sample was measured by MTT assay, and cytotoxicity to keratinocytes was evaluated by cell survival rate. The soothing effect was evaluated by detecting changes in inflammatory cytokines (IL-6, IL-1β, IL-8, TNF-α) secreted by UVB-stimulated keratinocytes with the sample treatment. Barrier repair efficacy was assessed in a Skinovo-Epi skin model by measuring changes in FLG (Filaggrin) and LOR (Loricrin) protein levels after topical application of the sample. Results: The sample showed low cytotoxicity on keratinocytes. The sample significantly reduced UVB-stimulated secretion of inflammatory cytokines in keratinocytes. Topical application of the sample increased FLG and LOR protein levels in the Skinovo-Epi skin model. Conclusions:Bletilla striata extract exhibits soothing and barrier repair activities in vitro. Bletilla striata extract reduces UVB-stimulated inflammation in keratinocytes and improves skin barrier function. The data provide novel experimental evidence supporting the innovative application of Bletilla striata for skin disorders. Bletilla striata has potential as a therapeutic herb for sensitive and damaged skin conditions.

Efficacy of plant extracts in growth promotion and onion purple blotch management: Unveiling metabolite fingerprinting of promising neem leaf extracts through GC MS

Exploration of diacerein as a neuroprotective adjuvant to Adenium obesum: An in-vivo study

Efficacy of Plant Extracts and Selective Insecticides Against Wheat Aphid in Faisalabad, Pakistan

Bihar hairy caterpillar (Spilosoma obliqua) is a sporadic, polyphagous and voracious foliage feeder attacking several host species of different families. Its impact is more pronounced in certain species of Cruciferae family, notably cabbage. The goal of the current study was to identify methods for pest control that are efficient, economical, and sustainable in order to combat the Bihar hairy caterpillar infestation on cabbage. The research was conducted to measure the efficacy of eight plant extracts in Entomology laboratory, Lamjung Campus at room temperature from March to April, 2019. There were eight treatments viz. Asuro (Justicia adhatoda), Bakaino (Melia azedarach), Ban fada (Lantana camara), Bojho (Acorus calamus), Kaligadi (Solanum nigrum), Neem (Azadirachta indica), Titepati (Artemisia vulgaris) and Tobacco (Nicotiana tabacum) in the experiment. Pure cultured insects were tested against treated leaf with four replications of each treatment placed in Complete Randomized Design (CRD). Antifeedant effect and mortality tests were performed for 24 hours and 15 days respectively. The results indicated that all the plant materials posses some sort of antifeedant and mortality effect to the insect. The statistical analysis revealed that both antifeedant effect (87.85%) and mortality (100%) were maximum in bakaino followed by neem. The result demonstrates a great potentiality of utilizing plant extracts against the pest, and suggests the incorporation of botanical extracts would be future alternative in pest management.

Theuse of plant extracts has been described ascredible alternative to synthetic insecticides in theprotection of field crops. This research work was conducted at Teaching and Research Farm, Ladoke Akintola University of Technology during the planting seasons of 2015 and 2016 to determine the efficacy of plant extracts –Tephrosia vogelii, Moringa oleiferia, Petiveriaalliaceaand Annona squamosa in the control of rodent infestation. The experiment was arranged in a randomized complete block design and each treatment was replicated three times. Synthetic insecticide (Lambdachyalothrin) and control were included in the experiment for comparison. Data were collected on plant stands attacked, vine length, yield and nutritional components of sweet potato tuber. The result showed that plant extracts treated sweet potato plants had significant lower rodent infestations when compared with unsprayed plant stands. Also, applied treatmentshad no negative effect on the vine length meanwhile yield obtained from botanical insecticides treated plants was two times higher than that of untreated plants which had the least tuber yield (0.90 t/ha).The tested plant extracts significantly improved the proximate contents of the harvested sweet potato tubers.Therefore, these plant extracts can be used in the field management of rodent infestation without any adverse effects on the nutritional components of the sweet potato tuber.

Production and quality evaluation of spiced anchovy fish sauce

In an approach towards the development of eco-friendly management, in vitro antifungal assay was conducted against Fusarium oxysporum f.sp. pisi (FOP), using plant extracts and biocontrol agents. Among six plants extract, maximum fungistatic effect was shown by garlic plant extracts with a 100% inhibition at higher (4%) concentrations followed by neem, turmeric, wild sedge, ginger and aloe vera. Eight isolates of Trichoderma spp. were tested for their ability to produce volatile and non-volatile metabolites against FOP. Studies indicated that volatile metabolites from isolate NCIPMCAU-69 caused maximum reduction (62.37%) in mycelial growth and minimum (18.57%) was recorded with isolate NCIPMCAU-109. In case of non-volatile, the highest per cent inhibition at 7.5 and 15% v/v concentration was recorded with the isolate NCIPMCAU-69 where the inhibition percentage was 14.53% and 20.97%, respectively. This research suggests that managing FOP with plant extracts and biocontrol agents could be a good choice for generating a profitable and risk-free product for the environment, animals, and human health.