Abstract The carotid artery is the utmost path of the blood to brain, scalp, and face. It is also a critical region of vascular diseases. Any change in hemodynamics of carotid artery brings impairment in the function of the whole cardiovascular system and may result in hypertension, kidney diseases, stroke, numbness, or paralysis on the side of the body opposite to the obstruction of the artery. In the current study, change in stiffness due to ageing and hypertensionis considered and investigated its effect on hemodynamics. Blood modeled as the non-Newtonian fluid flowing in pulsatile fashion which is not taken into account in many previous studies. In addition, viscoelastic properties of the arterial wall were incorporated to note the flow-induced deformation and effect of wall flexibility on hemodynamics by two-way fluid-structure interaction (FSI) algorithm.The variation in stiffness occurs in the range from healthy to disease arteryis 0.4 MPa to 4.5 MPa. Considering this fact, tenfold increase in wall stiffness caused a significant drop in the flow of blood
Read full abstract