Effects Of Coronavirus Disease 2019 Research Articles

Global research on emerging trends of obstetrics during the COVID-19 pandemic: A bibliometric analysis.

Coronavirus disease-2019 (COVID-19) has caused continuous effects on the global public, especially for susceptible and vulnerable populations like pregnant women. COVID-19-related studies and publications have shown blowout development, making it challenging to identify development trends and hot areas by using traditional review methods for such massive data. Aimed to perform a bibliometric analysis to explore the status and hotspots of COVID-19 in obstetrics. An online search was conducted in the Web of Science Core Collection (WOSCC) database from January 01, 2020 to November 31, 2022, using the following search expression: (((TS= ("COVID 19" OR "coronavirus 2019" OR "coronavirus disease 2019" OR "SARS-CoV-2" OR "2019-nCoV" OR "2019 novel coronavirus" OR "SARS coronavirus 2" OR "Severe Acute Respiratory Syndrome Coronavirus-2" OR "SARS-COV2")) AND TS= ("obstetric*" OR "pregnancy*" OR "pregnant" OR "parturition*" OR "puerperium"))). VOSviewer version 1.6.18, CiteSpace version 6.1.R6, R version 4.2.0, and Rstudio were used for the bibliometric and visualization analyses. 4144 articles were included in further analysis, including authors, titles, number of citations, countries, and author affiliations. The United States has contributed the most significant publications with the leading position. "Sahin, Dilek" has the largest output, and "Khalil, Asma" was the most influential author with the highest citations. Keywords of "Cov," "Experience," and "Neonate" with the highest frequency, and "Systematic Review" might be the new research hotspots and frontiers. The top 3 concerned genes included ACE2, CRP, and IL6. The new research hotspot is gradually shifting from the COVID-19 mechanism and its related clinical research to reviewing treatment options for pregnant women. This research uniquely delves into specific genes related to COVID-19's effects on obstetrics, a focus that has not been previously explored in other reviews. Our research enables clinicians and researchers to summarize the overall point of view of the existing literature and obtain more accurate conclusions.

Comparison of perinatal and neonatal outcomes of symptomatic pregnancy infected with SARS-CoV-2.

In this study, maternal and neonatal outcomes of pregnant women with positive severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) RNA tests were evaluated according to their symptomatic status. The clinical progression of SARS-CoV-2-positive pregnant women and the effect of coronavirus disease-2019 (COVID-19) on newborns was investigated. This retrospective cohort study was conducted at a tertiary pandemic hospital specializing in caring for pregnant women infected with SARS-CoV-2. We included patients with a positive SARS-CoV-2 polymerase chain reaction test at delivery, subdividing them into symptomatic and asymptomatic groups. Two hundred and forty-nine patients were included in the study. The mean age of the pregnant women in the symptomatic group was higher than those in the asymptomatic group (p=0.001). The iatrogenic preterm birth rates in the symptomatic and asymptomatic groups were 43.37% and 8.43%, respectively (p<0.001). Cesarean section rate was higher in symptomatic group (p=0.01). Maternal death was significantly higher in symptomatic pregnant women (p<0.001). The neonatal intensive care unit admission rate was higher in symptomatic pregnant women (p<0.001). The maternal and fetal outcomes for mothers with symptomatic infections tend to be worse, highlighting the importance of careful management, good follow-up and the advisability of closer monitoring.

Exploring the protective association between COVID-19 infection and laryngeal cancer: insights from a Mendelian randomization study.

Viral infections have been implicated as a risk factor for laryngeal cancer. Given the possible effects of Corona virus disease 2019 (COVID-19) on the laryngeal tissue, we investigated the causal link between COVID-19 and laryngeal cancer using a two-sample Mendelian randomization (MR) approach. We utilized genetic data from the 5th Genome-wide association studies (GWAS) edition of the COVID-19 Host Genetics Initiative (published on January 18, 2021) and a large-scale laryngeal cancer GWAS comprising 180 cases and 218,612 controls of European ancestry. We applied inverse variance weighting, MR Egger, and weighted median methods to infer causality. We performed sensitivity analysis using the "leave-one-out" method to verify robustness. We found no evidence of a causal association between gene-predicted COVID-19 and laryngeal cancer [Odds ratio (OR)=0.24 (95% Confidence intervals (CI), 0.05-1.26), P=0.09]. However, we observed significant inverse associations between gene-predicted COVID-19 hospitalization [OR=0.51 (95% CI, 0.28-0.95), P=0.03] and severe patients [OR=0.62 (95% CI, 0.43-0.90), P=0.01] and laryngeal cancer. Notably, the study detected important genetic variants, such as rs13050728, that modulate the expression of interferon alpha receptor 2 (IFNAR2), indicating possible roles for immune response pathways in both COVID-19 and cancer. This study reveals a potential interaction between COVID-19 severity, genetic factors, and laryngeal cancer, underscoring the importance of investigating the immune response mechanisms in both conditions. These findings contribute to the understanding of the complex interactions between COVID-19 and laryngeal cancer and may guide future research on the role of immune response, particularly involving IFNAR2.

Effects of COVID-19 Status on Hip Fracture Surgical Outcomes: An ACS NSQIP Study.

Studies have indicated that patients infected with the SARS-CoV-2 virus fare worse clinically after a traumatic injury, especially those who are older and have other comorbidities. This study aims to understand the effects of Corona Virus Disease 19 (COVID-19) diagnosis on patients undergoing surgery for hip fractures. This is a retrospective review of the 2021 American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) Targeted Hip Fracture database for patients who underwent surgery. Two cohorts were formed based on patients' preoperative COVID-19 status, as tested within 14days prior to the operation. Several clinical factors were compared. The COVID-positive cohort consisted of 184 patients, all of whom had a laboratory-confirmed or clinically suspected SARS-CoV-2 infection, while the COVID-negative cohort consisted of 12,211 patients with no infection. A lower proportion of COVID-positive patients had an emergent operation compared to the COVID-negative cohort (58.70% vs. 73.09%, p <.001). Preoperatively, the COVID-positive cohort showed higher rates of coagulopathy/bleeding disorders (22.83% vs. 14.12%), congestive heart failure (16.30% vs. 9.84%), diabetes mellitus (28.26% vs. 19.24%), and dementia (42.39% vs. 28.07%), with p ≤.005 for all. Postoperatively, a higher proportion of COVID-positive patients died (9.78% vs. 5.40%) or had pneumonia (8.70% vs. 3.65%), hospital readmission within 30days (10.87% vs. 6.76%), and pressure sores (8.15% vs. 4.55%), with p ≤.033 for all. The diagnosis of COVID-19 in hip fracture patients was associated with higher rates of postoperative complications, including mortality, when compared to COVID-negative patients, indicating the severity of the viral infection.

Prevalence of Oral Manifestations in COVID-19-Diagnosed Patients at a Tertiary Care Hospital in Kerala.

COVID-19, a pandemic since 2019, is still causing significant healthcare burden across the world. Although the disease primarily presents with respiratory symptoms, a multitude of signs and symptoms may be manifested elsewhere in the body. This study was to estimate the prevalence of oral manifestations in COVID-19 diagnosed patients and thereby understand the effects of corona virus disease on oral health. A total of 472 patients were evaluated using a questionnaire and further examined visually using a mouth mirror and a light source.The patients were evaluated for erythema, ulcers, macule, papule, vescicles, bullae or any other abnormal changes within the oral cavity. 103 patients (21%) were found to have oral lesions and 41 (39.8%) of them presented with palatal enanthem which was macular in nature. Candidiasis was noted in 19 (18.4%) patients, ulcer in 4 (3.8%), mucositis in 5 (4.8%), angular cheilitis in 3 (2.9%), white coating on tongue in 25 (24.2%) & depapillated tongue with glossitis in 6 (5.8%). Multivariate analysis was done using logistic regression.Tobacco chewing, malignancies and altered taste sensation were found to be independently associated with oral lesions. The study thus confirms the presence of oral lesions in diagnosed COVID-19 patients prompting healthcare professionals on a multidisciplinary approach towards this novel disease.

Gebelikten önce COVID-19 geçirenlerde ilk trimester uterine arter direnci, plasental volüm ve gebelik sonuçlarının incelenmesi

Aim&#x0D; There are studies showing that acquiring Coronavirus Disease 2019 (COVID-19) while pregnant might cause vascular damage, affect uterine blood circulation, and worsen pregnancy outcomes. In this study, we looked at the first-trimester placental development and pregnancy outcomes in people who conceived after getting better from COVID-19. We also looked into the durability of the COVID-19's effects on pregnancy.&#x0D; Matherials and Methods&#x0D; This prospective case-control study investigates placental volume and uterine artery Doppler flow differences in pregnant women with COVID-19 exposure within a year prior to pregnancy versus healthy pregnant controls.&#x0D; Result&#x0D; In a study involving 50 patients and 50 controls, it was discovered that demographic traits like age, birth rate, and body mass index were comparable. There were statistically insignificant slight differences in these results when different outcomes, including as oligohydramnios, preterm, preeclampsia, and intrauterine growth retardation, were studied. While birth weight revealed similarity between the two groups, placental volume and uterine artery Doppler results did not reveal any appreciable variations.&#x0D; Conclusion&#x0D; No distinction between the groups' placental or Doppler readings was found in the investigation that was completed. This work has helped identify the impacts of COVID-19 contracted prior to pregnancy on gestation, whereas previous study has mainly focused on the impact of COVID-19 infected during pregnancy.

Assessing COVID-19 Effects on Inflation, Unemployment, and GDP in Africa: What Do the Data Show via GIS and Spatial Statistics?

What are the effects of Corona Virus Disease 19 (COVID-19) on inflation, unemployment, and GDP in Africa? Using geo-coded cross-sectional data taken from the World Health Organization and International Monetary Fund, we investigate the spatial distribution of COVID-19 and its effects on inflation, unemployment, and Gross Domestic Product (GDP) in Africa by employing the Geographic Information System (GIS), multivariate analysis of covariance (MANCOVA), and spatial statistics. The entire dataset was analyzed using Stata, ArcGIS, and R software. The result shows (1) that there is evidence of a spatial pattern of COVID-19 cases and death rate clustering behavior in Africa, verifying the existence of spatial autocorrelation. The result also reveals (2) that COVID-19 has a negative effect on unemployment, inflation, and GDP in Africa. We confirmed that (3) temperature, rainfall, and humidity were statistically significantly associated with the spread of the COVID-19 pandemic in Africa. The comparison of the GDP of African countries before and after the pandemic shows (4) a large decrease in GDP, the highest in Seychelles (23 percent). The result of the study shows (5) that there has been a significant increase in inflation and unemployment rates in all countries since the outbreak of the pandemic as compared to the time before the outbreak. There is also evidence that (6) there is a significant relationship between death rate due to COVID-19 and population density; temperature with COVID-19 cases and death rate; and precipitation with death rate due to COVID-19. Therefore, respective governments and the international community need to pay attention to controlling/reducing the impact of COVID-19 on inflation, unemployment, and GDP, focusing on the indicated demographic and environmental variables.

Parental opinions and anxiety levels regarding the effects of coronavirus disease (COVID-19) on their children

ABSTRACT This study aimed to determine the anxiety levels of 540 parents, based on their COVID-19 experiences and views, and their effects on their children on online platforms between February and May 2021. The anxiety score of parents who had contracted COVID-19 or whose children had contracted COVID-19 was higher than that of parents whose children had not contracted. The parents’ main concerns were related to whether they, their child, or a family member would experience COVID-19 complications if their children contracted COVID-19, hospitalization during the pandemic, transmission of the virus to children, and the long-term impact of the pandemic on children. Protecting parents’ mental health is essential because of its effects on children’s mental health. Therefore, focusing on prevention methods and providing accurate information during and after the pandemic to improve parents’ knowledge is essential.

A possible mechanism of erectile dysfunction in coronavirus disease-19: Cavernosal smooth muscle damage: A pilot study

IntroductionStudies have reported that coronavirus disease 2019 (COVID-19) may cause erectile dysfunction (ED), however, its role in the pathophysiology of ED has not yet been fully elucidated. We aimed to elucidate COVID-19's effects on cavernosal smooth muscle, which has a pretty important role in erection physiology, by corpus cavernosum electromyography (cc-EMG). Materials and methodsTwenty-nine male patients aged 20–50 years who applied to the urology outpatient clinic due to ED were included in the study. Nine patients that had COVID-19 and were treated as outpatients were classified as group 1, 10 patients who were hospitalized due to COVID-19 were classified as group 2, and 10 patients who did not have COVID-19 were classified as the control group (group 3). Patients underwent diagnostic evaluation including International Index of Erectile Function (IIEF)-5 form, penile color Doppler ultrasonography (CDUS), cc-EMG, and fasting serum levels of reproductive hormones (07–11am). ResultsAccording to penile CDUS and hormonal values results, there was no significant difference between the groups. According to cc-EMG results, amplitudes and relaxation capacities of the cavernosal smooth muscle of patients in group 3 were significantly higher than those in the other groups. ConclusionsCOVID-19 can cause ED not only by psychogenic and hormonal factors but also with cavernosal smooth muscle damage.Clinical Trial Registration Number: NCT04980508.

The Impact of COVID-19 Pandemic on the Mental Health of Working Nurses at a Tertiary Care Hospital in Bangladesh

The psychological consequences of corona virus disease (COVID- 19) pandemic on health care professionals specially working nurses were serious due to their higher exposure. The aim of this study was to assess the impact of covid-19 pandemic on the mental health among working nurses. This institutional based cross sectional study was conducted at Bangabandhu Sheik Mujib Medical University (BSMMU) Hospital, Dhaka, Bangladesh, from July 2020 to June 2021. A total of 120 nurses, working in different units of BSMMU Hospital were included. Data were collected by face-to-face interview. The depression, anxiety and stress scale- 21 (DASS- 21) was used to assess the psychological impact of COVID- 19 on nurses. The prevalence of depression, anxiety and stress among working nurses was 25.8%, 44.2% and 64.1% respectively. Nurses working in the day shift duties, having no infection prevention training, lack of family support and excess work load were the factors significantly associated with depression (p&lt;0.05). While contact with confirmed cases and unavailability of infection prevention training were the factors that significantly increase the risk of developing anxiety (p&lt;0.05). On the other hand; lack of infection prevention training, excess work load and worries about bringing the virus at home were the factors significantly associated with developing stress among the nurses (p&lt;0.05). This study concluded that the prevalence of depression, anxiety and stress among nurses working in COVID-19 pandemic was high. Severity of stress was higher than anxiety and depression. Different risk factors were significantly associated with developing these mental disorders.

Consequences of coronavirus disease in women with breast cancer.

The ongoing coronavirus (COVID-19) pandemic produces widespread concerns, fear and stress throughout the world, and our country is no exception in that regard, which is a natural and normal human reaction to this inconsistent and uncertain situation for us all. For the purpose of this study a sociodemographic questionnaire was devised as well as a Serbian version of the self-reported Depression, anxiety and stress scale-21. The average age±[standard deviation (SD)] of the participants in the study was 49.20±11.2years. Regarding the depression score, 55/93 examinees (59.13%) had a normal score in the first examination, whereas in the second it rose to 57/93 (61.29%) and in the third it was 52/93 (58.06%). A normal anxiety score in March 2020 was seen in 52/93 (55.91%), whereas in September that year it was 53/93 (56.98%) and in March 2021 it was 39/93 (41.93%). The average value of stress score at the measurement in March 2020 was 5.51, lower in September (4.92) and in March 2021 it was 5.63. The results of this study refer to the process of clinical assessment and monitoring of breast cancer patients with evident symptoms of depression, anxiety and stress. Adequate counseling about COVID-19 is therefore a priority in an attempt to alleviate its psychological impact in these patients.

Agriculture Modernization and Enhancement Using Advanced Technologies

Food production must be considerably increased to maintain the world population, which is expected to reach 9.7 billion people by 2050. As a result, agriculture must be modernised and expanded in order to considerably increase food productivity; otherwise, achieving the second United Nations Sustainable Development Goal, Zero Hunger, will be challenging. Furthermore, humans are confronted with issues such as depleting natural resources and lands, climate change, unpredictable weather, and the effects of coronavirus disease. The impact of the COVID-19 pandemic on agricultural food yield has made food security a major global concern. Thus, the purpose of this work is to investigate the possibility of improving existing agricultural practises through mechanisation, automation, and adaptation of advanced technologies from industries, particularly research works from the Malaysian Agricultural Research and Development Institute (MARDI) into the new era of Agricultural Revolution 4.0, which uses Industrial Revolution 4.0 (IR4.0) advanced technologies to reduce labour force dependency, production time, and increase productivity and food security.

COVID-19's effect on the spatial integration of fish markets: Evidence from carp price in China

While curbing the spread of Coronavirus Disease 2019 (COVID-19), lockdown policies and “stay-at-home” restrictions caused massive supply chain disruptions worldwide. This led to breaks in spatial market integration, which could further lead to market inefficiency and resource misallocation. Taking daily price data from 2016 to 2021, this study investigates COVID-19's effect on the spatial market integration of fish in China using cointegration tests. We find a high degree of spatial market integration for fish in China before the COVID-19 pandemic. Further, our results show that COVID-19's effect on the spatial market integration of fish varies spatially in China. Specifically, COVID-19 reduces the degree of spatial market integration in most provinces, especially those with high infection rates. Meanwhile, the degree of spatial market integration in provinces with low infection rates remains high. Therefore, the government should be regionally specific when formulating market recovery policies.

Comparison of the Unit Cost of Diagnostic Imaging Services Before and During the COVID-19 Pandemic Using the Activity-Based Costing (ABC) Method

Background: The consequences of coronavirus disease (COVID-19) pandemic, especially the financial burden imposed on the healthcare systems and hospitals, have been unpredictable around the world. Radiology wards have been exposed to the highest burden during this pandemic. Objectives: This study aimed to calculate the cost of diagnostic imaging services before and during the COVID-19 pandemic, using the activity-based costing (ABC) method in an important diagnostic center of COVID-19 in Khorramabad, Iran. Patients and Methods: In this retrospective study, data were extracted from the hospital accounting sources in the radiology ward over two years (2019 - 2021). According to the ABC method, four types of cost were defined, including wage, supporting services, Consuming materials, and overhead expenses. Therefore, based on the monthly number of services, the unit cost of each service was calculated. Results: The unit cost of all services during the COVID-19 pandemic was higher than before, except for CT scan (before: 6.1 United States dollar [USD]; during: 5.6 USD) (P = 0.008). The unit cost of MRI service was 5.7 USD before the pandemic and 7.1 USD during the pandemic (P = 0.57); the cost per radiography service was 1.8 USD before the pandemic and 7.1 USD during the pandemic (P = 0.01); and the cost per sonography service was 1.1 USD before the pandemic and 2.8 USD during the pandemic (P = 0.04). Finally, the cost of mammography increased dramatically during the pandemic (before the pandemic: 21.3 USD; during the pandemic: 48.2 USD) (P = 0.004). Conclusion: The COVID-19 pandemic has increased the radiology department expenses. The cost of CT scan services decreased due to the large number of services provided compared to the pre-pandemic period.

Effects of Coronavirus Disease on Trade for New Zealand

Effects of Coronavirus Disease on Trade for New Zealand

A Systematic Review Approach in Understanding the COVID-19 Mechanism in Diabetes and its Progression to Diabetic Microvascular Complications

Introduction: In uncontrolled hyperglycemia, lungs, tongue, oropharyngeal and nasopharyngeal airways having increased glycosylated angiotensin-converting enzyme 2 (ACE2) can serve as good viral binding sites for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leading to a greater tendency and considerable risk of prolonged life-threatening disease. This review was written with the objective to extract the recent advances, updates, and discoveries about the effects of coronavirus disease-2019 (COVID-19) on patients with diabetes and its microvascular complications. It was further written with the aim to discuss the current state of knowledge that has not yet been confirmed or unconfirmed, leading to various debatable issues about COVID-19-associated with microvascular complications in diabetes mellitus. Materials and Methods: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and searched scientific sites related to our review article such as Web of Science, Embase, PubMed, Scopus, Google Scholar, and MEDLINE of last nearly two and half years. Results: The individuals who are suffering from type 2 diabetes mellitus experience more organ damage by SARS-Cov-2 due to cytokine storm. The pro-inflammatory state, lower primary immune system response, and increased ACE2 level with dysregulation of vascular function and the prothrombic state in patients with diabetes may increase the vulnerability for COVID-19 and worsened prognosis. The patients have reduced prognosis leading to microvascular complications such as diabetic nephropathy, neuropathy and retinopathy. In diabetes retinopathy, it induces the changes in the vasculature of the retinal veins. These viruses can directly affect the nervous tissue and/or can indirectly via activating the immune system-mediated mechanisms leading to diabetic neuropathy as well. Conclusions and Implications: During the cytokine storm the amount of D-dimer in the serum gets significantly increased, due to increased activating plasmin at the early stage of inflammation. Uncontrolled hyperglycemia leads to diabetic complications leading to increased mortality rate in patients with COVID-19. Thus, diabetes and its associated microvascular complications may lead to the severity and mortality in the patients with COVID-19. More of clinical practice and further studies should be implicated through this review article. Laboratory findings and clinical records are of much help in patients with diabetes and COVID-19. Worldwide studies from different countries apart from China should be considered to reach a conclusion about the conditions of patients with diabetes and microvasculature complications around the world.

Immunomodulation and anti-inflammatory effects of Baccharis dracunculifolia and Brazilian Green Propolis: A integrative literature review

Inflammatory and oxidizing factors are important for the triggering of diseases such as arthritis, lupus, and currently, the serious effects of coronavirus disease (COVID-19), which has an increase in inflammatory factors during its development and, consequently, can be mitigated by the beneficial effects of Baccharis dracunculifolia (Bd) and Brazilian Green Propolis (BGP). A literature search through PubMed, ResearchGate and HOLLIS Harvard Library Online Catalog was performed from the date of inception until 01/07/2021. A combination of the following keywords was used: propolis and baccharis dracunculifolia, anti-inflammatory, antioxidant and immunomodulation. The results of inflammatory and oxidizing factors shown by the study are important for the medical field, in addition to understanding how there are numerous compounds that are not yet known and mainly due to their possible treatments for various diseases. We conclude that BD and BGP are important for the reduction of inflammatory and oxidizing factors, which can be beneficial in immunological diseases and in exorbitant inflammatory factors as observed in COVID-19.

A Study of the Effects of Corona Virus Disease (COVID-19) in Thailand

A Study of the Effects of Corona Virus Disease (COVID-19) in Thailand

The Effects of Corona Virus Disease (COVID-19) on Restaurant Marketing Strategies of Café Restaurant around San Pedro, Laguna

The Effects of Corona Virus Disease (COVID-19) on Restaurant Marketing Strategies of Café Restaurant around San Pedro, Laguna

The effect of coronavirus disease-2019 (COVID-19) according to gender on health-related quality of life

Aim: The purpose of this study was to evaluate the changes in health-related quality of life of hospitalized patients with the diagnosis of coronavirus disease-2019 (COVID-19) according to gender. Material and Method: The medical records of 77 patients (37 females and 40 males) who were hospitalized for COVID-19 were examined. Sociodemographic features including age, gender, marital status, comorbid diseases, duration of hospitalization, the period after discharge, symptoms of COVID-19 disease were analyzed. Short Form 36 (SF-36) was applied to all patients for evaluating the health-related quality of life pre and post COVID-19. Results: The median scores of physical function, bodily pain, vitality, social functioning and general health perceptions before COVID-19 were statistically significantly higher than the scores after COVID-19 in both gender. Social functioning and the scores were lower in females than males for pre and post COVID-19 period and the differences were statistically significant. Conclusions: The findings of this study revealed that health-related quality of life is affected by COVID-19 for both genders, mostly females.