Effects Of Chloral Hydrate Research Articles

Effect of Chloral Hydrate on Growth of Hair

STUDIES on the percutaneous toxicity of liquids applied as small (100µ) droplets to the guinea pig-have shown that the presence of hair prevents some of the droplets from reaching the skin. Consequently, when the test liquid is applied in this droplet size, it shows less toxicity than an equivalent weight of large (400µ) droplets1.

Distinctive features of the action of hypnotics after nociceptive stimulation of animals in a state of hypothyroidism

The sleep-inducing effect of chloral hydrate (0.3 mg/g body weight) and sodium amytal (0.06 mg per g) was studied on white mice with hypothyroidism. The latter was attained by daily (during 3 weeks) administration of methylthiouracil (5 mg per mice) by a stomach tube. Pronounced nociceptive stimulation preceded the administration of sleep-inducing drugs in certain experiments. Sleep-inducing substances caused much less effect on animals with hypothyroidism than on normal animals. After nociceptive stimulation the sleep-inducing effect of chloral hydrate on animals with hypothyroidism was much less than that in normal animals. After nociceptive stimulation the sleep inducing effect of chloral hydrate increased in animals with hypothyroidism more intensely than in in normal animals, while the effect of sodium amytal had a tendency to decrease.

Effect of Chloral-hydrate on Certain Forms of Artificial Diabetes

Effect of Chloral-hydrate on Certain Forms of Artificial Diabetes

Observations and Experiments with the Microscope, on the Chemical Effects of Chloral Hydrate, Chloroform, Prussic Acid, and other Agents, on the Blood

Observations and Experiments with the Microscope, on the Chemical Effects of Chloral Hydrate, Chloroform, Prussic Acid, and other Agents, on the Blood