The effect of run-out is clearly noticed in micro-end-milling operations, while the same run-out creates negligible change at the cutting force profile of conventional end-milling operations. In this paper, the cutting force characteristics of micro-end-milling operations with tool run-out are investigated. An analytical cutting force model is developed for micro-end-milling operations with tool run-out. The proposed model has a compact set of expressions to be able to estimate the cutting force characteristics very quickly compared to the numerical approaches. The cutting forces of micro-end-milling operations simulated by the proposed model had good agreement with the experimental data.