Background and Objectives: This study investigated the effectiveness of logotherapy on death anxiety, pain catastrophizing, pain acceptance, and severity of pain in prostate cancer patients. Subjects and Methods : The research design was an experimental pretest-posttest with a control group. At first, 40 hospitalized men in a treatment center were selected by using the purposive sampling method. The experimental group was treated for eight 45-minute sessions by training logotherapy. All subjects completed the questionnaire at the beginning of the study, immediately after the intervention, and one month after the treatment (one-month follow-up). For data analysis, 1-way analysis of variance was used. Results The results indicated that logotherapy in the experimental group was more effective than the control group in reducing death anxiety, pain catastrophizing, pain acceptance, and severity of pain in prostate cancer patients. The follow-up results also showed that the effect of logotherapy was sustained on death anxiety, pain catastrophizing, pain acceptance, and severity of pain in prostate cancer patients. Conclusion The results showed that Logotherapy has an effect on death anxiety, pain catastrophe, pain acceptance and pain intensity in patients with prostate cancer
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