Ectopic Thyroid Mass Research Articles

THU674 Papillary Thyroid Carcinoma Presenting As A Benign Ectopic Thyroid Mass In The Anterior Mediastinum. A Case Report

Abstract Disclosure: M.V. David-santos: None. C. Narvacan-montano: None. Background: Ectopic Thyroid Tissue (ETT) is a rare developmental anomaly that is due to the failure of the thyroid gland to assume its position in front of the trachea. Ectopic Thyroid tissue in the mediastinum is very rare, with only a few cases reported in the literature. An incidental Papillary Thyroid Carcinoma presenting as a mediastinal mass that turns out to be benign ectopic thyroid cells is even rarer. Case: This is the case of a 33-year-old female who presented with sudden onset difficulty of breathing and chest heaviness. On workup, she was found to have an anterior mediastinal mass, which showed ectopic thyroid cells on biopsy. Further evaluation of the neck area revealed a 1.25 cm x 1 x 1.13 cm nodule on the thyroid gland which showed suspicious for Papillary Thyroid Carcinoma on Fine needle aspiration biopsy. The patient underwent Total Thyroidectomy and Excision of the Anterior Mediastinal Mass. The histopathologic report of the thyroid mass revealed a Conventional Unifocal Papillary Thyroid Carcinoma, while the excised tissues comprising the mediastinal mass were consistent with benign ectopic thyroid tissues with colloid goiter. Conclusion: The presence of the ectopic thyroid mass in the anterior mediastinum may be a potential area for metastasis. The final pathologic report nevertheless, categorizes this Papillary thyroid carcinoma as having a low risk of metastasis as per the American Thyroid Association Classification of 2015. Hence the conservative approach of Suppression therapy and active surveillance is the choice of management for this unusual case. Presentation: Thursday, June 15, 2023

Ectopic thyroid mass in mediastinum with normal thyroid function and location

There are very few cases of mediastinal ectopic thyroid reported in the literature. An asymptomatic 49-year-old woman with a mediastinal mass is the subject of this report. Mediastinal ectopic thyroids’ epidemiology, clinical manifestations, diagnosis, and treatment were also discussed. A mediastinal ectopic thyroid ought to be viewed as a differential finding among all mediastinal masses. Careful extraction is suggested for both the analysis and treatment of this condition in light of its true capacity for harm and pressure on mediastinal structures. The clinical significance of mediastinal ectopic thyroid is demonstrated in this case.

Ectopic thyroid mass separately present in mediastinum and not a retrosternal extension: a rare case report

Retrosternal extension of goiter is one of the most common types of masses in the superior mediastinum. These types of goiters classically present with compressive symptoms such as dyspnoea, dysphonia, dysphagia, or sleep apnea. Surgical treatment with a total thyroidectomy and complete removal of the intrathoracic portion of thyroid is the gold standard treatment. These cervico-mediastinal lesions at times may not be continuous, and a sternotomy may be required for complete and safe excision of the mediastinal mass to achieve decompression of the surrounding structures and preventing the hemorrhagic complications if attempted from cervical incision.

A new lateral neck mass in a 63-year-old man with multinodular goiter.

Described is a rare presentation of ectopic thyroid tissue as a lateral neck mass. This case raises the awareness that a lateral neck mass (including ectopic thyroid mass) needs appropriate investigations to rule out malignancy.

SAT-611 Abdominal Goiter

A 79 year old woman with hyperlipidemia, hypertension, congestive heart failure was referred for evaluation of ectopic thyroid tissue found on a liver biopsy. The patient originally presented with abdominal pain and was noted to have a liver mass measuring 5.7 x 3.2 x 5 cm on computed tomography (CT) that appeared contiguous with the medial segment of the left hepatic lobe. A subsequent ultrasound (US) showed the same 3.1 x 4.7 x 4.7 cm ovoid mass with a central focus of increased echogenicity and a well-circumscribed margin; a fine needle aspiration (FNA) of the hepatic lesion showed thyroid follicular cells and abundant colloid. Magnetic resonance imaging of the abdomen was done 6 months later, which showed a soft tissue abnormality in the porta hepatis extending centrally into the liver of decreased T2 signal intensity relative to the liver and containing iron deposition. The size of the lesion by MRI was unchanged in comparison with the CT. Eight years later, she presented to the Emergency Room with suprapubic abdominal pain. On CT, she had a large mass (8.3 x 5.5 x 7.1 cm) in the porta hepatis with mass effect upon the gallbladder and pancreas without biliary dilatation or evidence of frank invasion. An FNA was repeated, again showing benign appearing thyroid tissue (bland follicular cells without features of papillary thyroid cancer and abundant colloid). Immunohistochemical staining for TTF-1 was positive, supporting thyroid origin. Thyroid function tests were normal ( TSH-0.85 uIU/mL; free T4 direct- 1.1 ng/dL; and total T3 - 125 ng/dL) There are only three prior case reports detailing ectopic thyroid tissue in the porta hepatis (1). Benign ectopic thyroid tissue in the liver is generally explained as a metaplastic phenomenon, as the thyroid shares a common embryologic origin with the liver and proximal segment of the gastrointestinal tract (2). Workup typically includes CT or US imaging, followed by I-123 imaging to determine the presence of functional thyroid tissue, followed by a biopsy. The prevalence of all ectopic thyroid tissue is 1 per 100,000-300,000 persons, with less than 1% being malignant. The majority (85%) of malignant ectopic thyroid tissue is papillary thyroid cancer. Excision of ectopic thyroid mass in the liver has generally been favored, due to their minor malignant potential. The patient has been referred to Surgical Oncology/Endocrine Surgery for possible resection.

Ectopic thyroid mass in the right ventricle: A case report

Ectopic thyroid is a rare congenital embryonic anomaly. Ectopic thyroid tissue can be located anywhere during its descent, but it is found primarily at the base of the tongue and in the mediastinum. It is very rarely found in the heart. Here, we report a rare case of cardiac ectopic thyroid tissue in a 53-year-old woman who presented with chest pain. Echocardiography revealed an intracardiac mass that was removed successfully. Histopathology confirmed that the mass was thyroid tissue without malignancy.

Right ventricular outflow tract tumour: an unsuspected intracardiac ectopic thyroid mass

Ectopic thyroid is a rare embryogenic anomaly that occurs during its migration from foramen caecum to its pretracheal position. An intracardiac ectopic location is even rarer and found most commonly in the right ventricular outflow tract in sporadic reports. While surgery in symptomatic patients seems appropriate, resection of non-neoplastic ectopic tissue remains a clinical equipoise. Its occurrence is often unsuspected by clinicians, but its possibility should be considered due to its typical location in the right ventricular outflow tract. Unlike true neoplastic intracardiac tumour which mandates surgical resection, both surgical and non-surgical approach may be considered for an intracardiac ectopic thyroid mass.

Redefining anatomy in a case of midline subhyoid ectopic thyroid.

Ectopic thyroid is an uncommon embryological aberration of the thyroid descent. Subhyoid median ectopic thyroid gland is a result of incomplete descent of the thyroid anlage and is characterized by a cosmetically unacceptable ovoid mass of thyroid tissue in the midline overlying the thyroid cartilage and thyrohyoid membrane. A normally placed thyroid gland is not detectable and in most cases all functioning thyroid tissue is located within the mass. Most of the ectopic thyroids are usually mistaken for a thyroglossal cyst and excised. Severe myxedema follows removal. Many cases have been reported in the literature, none of which was recognized prior to operation. All patients were operated upon for removal of a thyroglossal duct cyst. The diagnosis was missed at operation and in these cases severe myxedema was universal. The cause of the myxedema was not always immediately recognized. Therefore, many diagnostic tests including thyroid function test, ultrasound of the neck, and thyroid scanning had been recommended in the preoperative evaluation of a thyroglossal cyst. Here, we present a case of ectopic thyroid mass which was the only thyroid tissue present in the neck. So, division and repositioning of the thyroid mass thereby redefining the anatomy was done with good cosmetic results.

Redefining Anatomy in a Case of Midline Subhyoid Ectopic Thyroid

ABSTRACTEctopic thyroid is an uncommon embryological aberration of the thyroid descent. Subhyoid median ectopic thyroid gland is a result of incomplete descent of the thyroid anlage and is characterized by a cosmetically unacceptable ovoid mass of thyroid tissue in the midline overlying the thyroid cartilage and thyrohyoid membrane. A normally placed thyroid gland is not detectable and in most cases all functioning thyroid tissue is located within the mass. Usually it is mistaken for a thyroglossal cyst and excised. Severe myxedema follows removal. Many cases have been reported in the literature, none of which was recognized prior to operation. All patients were operated upon for removal of a thyroglossal duct cyst. The diagnosis was missed at operation and in these cases severe myxedema was universal. The cause of the myxedema was not always immediately recognized. Therefore, many diagnostic tests including thyroid function test, ultrasound of the neck and thyroid scanning had been recommended in the preoperative evaluation of a thyroglossal cyst. Here, we present a case of ectopic thyroid mass which was the only thyroid tissue present in the neck. So division and repositioning of the thyroid mass thereby redefining the anatomy was done with good cosmetic result.How to cite this articleNaik KM. Redefining Anatomy in a Case of Midline Subhyoid Ectopic Thyroid. Int J Head and Neck Surg 2012;3(3):179-181.

Intratracheal Ectopic Thyroid Mass

A 39-yr-old woman presented with dyspnea and cough. She had undergone total thyroidectomy for multinodular goiter 15 yr earlier, with subsequent T4 replacement therapy. Inspiratory stridor was noted. Serum TSH was 2.95 mIU/ml (normal, 0.3–4.0 mIU/ml). A magnetic resonance image (MRI) of the neck showed a subglottic tumor with severe occlusion of the trachea (Figs. 1 and 2). Direct laryngoscopy revealed a subglottic mass covered with normal mucosa. Tc scintigraphy showed homogenous subglottic uptake compatible with a thyroid tissue. A transtracheal surgical approach was used to remove the tumor. Pathology showed a follicular thyroid tissue with no features of malignancy.

Lingual thyroid in association with a lateral ectopic thyroid mass

Lingual thyroid in association with a lateral ectopic thyroid mass