Multifunctional molecular imprinting-enhanced transistor and electrochemical dual-mode sensor for ultra-wide range detection of halogenated phenols.

Spatiotemporal variability, source apportionment, and ecological risk assessment of heavy metals in sediments: A case study of the Panzhihua reach (Wudongde reservoir tail).

A comprehensive review of per- and polyfluoroalkyl substances (PFASs) in estuaries and coasts of China: Distributions, sources, ecological risk assessment, and interfacial processes.

A novel perspective on ecological risk assessment of Polycyclic Aromatic Hydrocarbons (PAHs) based on multi-source data fusion.

Antibiotics in northern China's largest shallow wetland lake: Occurrence, bioaccumulation, ecological risk, and indicator screening.

Combined effects of marine heatwaves and nano-titanium dioxide (nano-TiO₂) on the physiological fitness in the mussel Mytilus coruscus.

Dynamic distribution characteristics and ecological risks of antibiotics in typical subtropical tidal river.

Seawater quality criteria derivation and ecological risk assessment for tris (2-chloroisopropyl) phosphate in China.

Emerging contaminants in the Yiwu River adjacent to China's leading international trade hub: Occurrence, ecological risk assessment and influencing factors

Sources and distribution of atmospheric microplastics in Northwest China river valleys via land use.

Amitriptyline and nortriptyline induce ocular toxicity in early life stage zebrafish (Danio rerio).

High-resolution mapping decouples hydrodynamic sorting and sediment transport as primary drivers of PAH distribution in the East China Sea inner shelf.

Developmental toxicity of carboxylated microplastics in zebrafish mediated by mitochondrial dysfunction and inflammatory activation.

Double-stranded RNA (dsRNA)-based biopesticides are a promising new method of pest management. These biopesticides leverage the endogenous RNA interference pathway to selectively regulate expression of key genes involved in growth and development in pests, providing the potential to minimize harmful environmental effects by highly specific targeting. As dsRNA-based biopesticides are presented for regulatory review, evaluating potential off-target effects on nontarget organisms (NTOs) in a manner that may be unique to this novel sequence-specific mode of action is crucial. To address this, we propose here a bioinformatics framework for consideration of sequence-specific off-target effects in NTOs. This framework includes careful consideration of NTOs based on potential exposure and susceptibility and recommends standardizing analyses to search for 21-nucleotide stretches of perfect identity and 80% overall identity between the dsRNA and off-target transcripts. We recommend a three-pronged approach to ensure a comprehensive risk assessment: (a) phylogenetic analysis of gene orthologs that defines the taxonomic scope of sequence similarity, (b) broad searches of large databases to identify potential unexpected similarity in distantly related species, and (c) full transcriptome analyses in NTO species of particular concern for a thorough understanding of all potential hazards. Finally, we recommend considering the results of bioinformatic analyses in the context of risk characterization, which means considering likely exposure to the dsRNA-based pesticide and potential susceptibility or barriers to dsRNA uptake. This approach enables a robust ecological risk assessment for dsRNA-based biopesticides and a regulatory path forward for this promising new pest management tool.

Geospatial distribution of hazardous metals and other elements in stream sediments of Akum, Cameroon: Insights into mineral exploration and ecosystem health using indexical and multivariate approaches.

Crosstalk regulation between gut microbiota and DNA methylation: Sex-specific effects of intestinal metabolic activities induced by prothioconazole and prothioconazole-desthio in zebrafish.

Metal contamination in the coastal zone of Gökova Gulf including special environmental protection area (Western Turkiye): Sediment quality indices and environmental implications.

Marine ecotoxicity evaluation of 10 per- and poly-fluoroalkyl acids using three USEPA short-term chronic bioassays.

Distributions and health risk assessment of heavy metals in the Mersin Bay, Northeastern Mediterranean Sea: Sediments, macroalgae (Enteromorpha sp.), and fish species (Mugil cephalus, Mullus barbatus, Pegusa lascaris).

Impact of CO2-induced seawater acidification at increased hydrostatic pressure on cellular-level responses of the infaunal nereid Hediste diversicolor.