Enhanced epileptic seizure detection using CNNs with convolutional block attention and short-term memory networks.

Objectives: To assess current detection and intervention strategies for pediatric asthma, frontline healthcare providers in an urban environment, and to identify provider-level barriers to guideline-concordant care. Methods: Between March and May 2025, a cross-sectional multicenter survey was administered to a stratified random sample of 450 healthcare providers (pediatricians, general practitioners, nurse practitioners, and registered nurses) working in primary care clinics and pediatric hospitals. A 48-item questionnaire (practice subscale Cronbach’s α = 0.84) measured screening practices, diagnostic test availability (spirometry, FeNO), use of personalized asthma action plans (PAAPs), early-intervention strategies, and perceived barriers. Data collection were electronic, analyses were performed using SPSS v.29. Results: Of 450 invited, 338 providers completed the survey (response rate 75.1%). Of those surveyed, 64.8% report use of symptom-based screening for asthma in children (n = 219), 42.6% report office spirometry availability (n = 144), and 9.8% report point-of-care FeNO availability (n = 33). Among the participants, 51.2% reported giving personalized asthma action plans on a routine basis. When adjusted for years in practice and setting, multivariable logistic regression showed that having on-site spirometry (adjusted OR 2.09, 95% CI 1.38-3.17, p < .001) and having taken training for asthma in the last 3 years (adjusted OR 1.84, 95% CI 1.22-2.78, p = .004) were significant predictors of guideline-concordant practice (as defined below). Main perceived barriers included lack of equipment/time (68%), inadequate training (54%), and not enough reimbursement (41%). Conclusions: Across the various sites in this urban sample, objective testing (spirometry, FeNO) and systematic use of PAAPs were inconsistently outfitted. On-site spirometry and recent provider training were linked to a higher probability of early detection and intervention in accordance with guidelines. Interventions to improve access to objective testing and educate primary care providers may lead to better early detection and less preventable exacerbations.

Early sepsis prediction in the emergency department using machine learning.

Revolutionizing pediatric obesity intervention strategies: From traditional growth reference tools to AI-enabled pediatric obesity clinical decision support systems.

Objective We herein report our experience with medically treated patients presenting with dropped head syndrome (DHS) due to isolated neck extensor myopathy (INEM) or primary hyperparathyroidism (PHPT)-related myopathy, focusing on the treatment response and the correlation between muscle pathology and INEM outcomes. Methods This single-center retrospective observational study reviewed 20 consecutive patients who presented with DHS as their primary complaint between March 2021 and June 2025. Sixteen patients were included in this study: 13 with INEM who received immunotherapy as the primary medical treatment and 3 with PHPT-related myopathy who received oral evocalcet. The severity of DHS and treatment response were graded semi-quantitatively. Muscle biopsy findings were analyzed in one patient with INEM. We conducted a literature review of biopsy-proven INEM cases. Results INEM was the most common cause of DHS (13/20). Patients with INEM with a shorter disease duration experienced dramatic improvement, whereas those with a longer disease duration showed only partial improvement. Relapse occurred in six patients with INEM. All three patients with PHPT-related myopathy achieved complete remission of DHS with oral evocalcet. Although our single biopsy case showed no pathological inflammation and responded well to immunotherapy, a literature review revealed that inflammatory infiltrates were present in 38% of the 56 INEM cases and correlated with a significantly better immunotherapy response. Conclusion INEM is the predominant etiology of DHS at initial presentation, and immunotherapy is an effective management strategy, especially with early intervention. PHPT-related myopathy represents another important etiology of DHS, with a favorable response to medical therapy with evocalcet.

Machine learning predicts scarring progression in lichen planopilaris: A multidimensional model integrating trichoscopy, vitamin D, and diagnostic timelines.

Infants and Toddlers With Moderate-To-Severe Cerebral Palsy Receive Very Low Doses of In-Person Rehabilitation.

Testing the effectiveness of a professional development program to support practitioners' ability to provide caregiver coaching for children younger than age 3 with sensory-based challenges is a professional responsibility. To evaluate the impact of the Sensory Approaches to Infant/Toddler Learning (SAIL) program on practitioners' knowledge of and confidence in caregiver coaching and its acceptability, appropriateness, and feasibility. Prospective cohort pilot study with data collected at three time points. Large midwestern pediatric hospital with established evidence-based practice, research, and professional development infrastructure. Occupational therapy practitioners with one or more children younger than age 3 on their caseload were eligible and invited via email. SAIL included five asynchronous webinars (sensory integration [SI] theory and intervention), 12 biweekly mentorship sessions over 6 mo, and 3 mo access to the Sensory Processing Measure-2 Sensory Professional Reasoning Kit to Promote Infant/Toddler Participation (SPM-2 SPARK). Practitioner knowledge of and confidence in SI and SI-based caregiver coaching were measured with an investigator-developed survey. Ratings of acceptability, appropriateness, and feasibility of SAIL components were completed using validated measures. Participants significantly improved in all knowledge and confidence domains from pretest to posttest and from pretest to follow-up; no significant change occurred from posttest to follow-up. Participants rated the webinar series and SPM-2 SPARK as highly acceptable, appropriate, and feasible. SAIL is a feasible and well-received approach to enhance capacity for SI-based caregiver coaching. Further research is needed with larger, diverse samples to confirm the results and assess long-term use. Plain-Language Summary: Sensory integration and processing challenges can disrupt infants' and toddlers' participation, yet the literature documents that occupational therapy practitioners feel underprepared to coach caregivers. Despite consensus on the need for postprofessional education and mentorship, evidence of effective approaches is limited. Some young children process and respond to sensory information differently. This includes what they see, feel, hear, taste, and smell, as well as their sense of movement and balance, their sense of body position, and how they use these senses together. Differences in processing and combining these senses can make daily activities such as eating, sleeping, or playing harder. Early intervention, which provides services for children from birth to age 3, often includes occupational therapy practitioners who work with caregivers to help children join in everyday routines. Yet there are reports that many practitioners do not feel confident coaching caregivers about sensory needs. This project tested the Sensory Approaches to Infant/Toddler Learning (SAIL) program, which included online training, mentoring, and practical resources. After the program, practitioners reported more knowledge and confidence in working with families. These results are a first step toward showing that SAIL is effective, but more research is needed.

This study aimed to investigate sex-specific differences in short- and long-term outcomes following surgical repair of acute type A aortic dissection (ATAAD). We hypothesized that female patients present at higher baseline risk, contributing to different outcomes than male patients. We performed a retrospective analysis of 765 patients (482 males, 283 females) who underwent ATAAD surgery from June 1984 to December 2024. Data included demographics, clinical presentation, operative variables, and postoperative outcomes. The primary endpoint was in-hospital mortality, and secondary endpoints included in-hospital morbidity measures and long-term mortality. Logistic regression model was utilized predictors of in-hospital mortality, and Cox proportional hazards regression was used for long-term survival. Females were older, had higher rates of cerebrovascular events, and exhibited more iatrogenic dissections than males. In-hospital mortality was comparable (females 13.1%, males 16.4%; p = 0.258). In unadjusted cox regression model, female sex was associated with higher long-term mortality (Hazard Ratio (HR) = 1.319; p = 0.008), but this effect was not significant after risk adjustment (HR = 1.140; p = 0.241). Independent predictors of in-hospital mortality included malperfusion, older age at presentation and longer cardiopulmonary bypass times. Although female patients exhibited worse unadjusted long-term survival, these differences were largely attributed to preoperative risk factors rather than sex alone. The findings underscore the importance of timely diagnosis and individualized management for older female patients. Improving awareness and early intervention may reduce disparities and optimize outcomes in ATAAD repair. The online version contains supplementary material available at 10.1007/s12055-025-02059-7.

Preoperative hyperglycemia and postoperative adverse events in geriatric hip fracture surgery: Glycemic thresholds and exposure persistence.

Wellbeing Is Not the Absence of Psychological Distress: A Longitudinal Descriptive Analysis in Early Adolescence.

Molecular regulation of coagulation by heparin-bound plasma Latexin.

Lightweight element-wise product enhanced neural network for efficient arrhythmia detection on embedded devices.

Prevention of readmission by intensified follow-up after transcatheter aortic valve implantation: Feasibility results of the PREMISS randomised controlled trial.

Localization and duration dependent effects of pediatric refractory epilepsy on language function.

Effects of cranial X-ray irradiation in Presymptomatic 3×Tg-AD mice.

Construction of nomogram prediction model for suicide risk in patients with mental disorders: A retrospective study based on general hospital medical records.

New insights into the management of complicated pneumonia in children: A systematic review of randomized controlled trials.

Electrochemical VWF Biosensors Based on Two-Step Synthesized rGO@AuNPs Nanocomposites for Early Prediction of ECMO Bleeding Complications.

Associations Between Visual Impairment and Homebound Status, Home Hazards, and Support Service Utilization: The National Health and Aging Trends Study.