Abstract Bullying is a behavior highly prevalent in schools worldwide and is associated with several mental disorders later in life. Considering its prevalence and impact in mental health, it is being recognized as a public health problem. We aimed to identify patterns of bullying victimization and perpetration in children and adolescence, and investigated its association with school performance, alcohol use and sociodemographic factors. A latent class analysis was conducted using baseline data collected from a randomized controlled trial conducted to evaluate the effectiveness of the drug prevention program PROERD (the Brazilian adaptation of the the US program 'Keepin it REAL”) carried out among 1.742 students in 5th grade and 2.316 in 7th grade, from 30 public schools of São Paulo city, Brazil. Two models of four latent classes each were identified among the students, in 5th and 7th grade: Low bullying, Moderate bullying victimization, High bullying victimization and High bullying victimization and perpetration. In both grades, we found that alcohol use were associated to all bullying latent classes (e.g High bullying victimization and perpetration (aOR=5,63; 95%CI = [3,05; 10,38] and aOR=3,29; 95%CI = [1,28; 8,43], 5th and 7th grade respectively). In 5th grade, girls were more likely to belong to the “High bullying victimization” class and to “Moderate bullying victimization” (aOR=1,75; 95%CI = [1,02; 3,01] and aOR=1,47; 95%CI = [1,16; 1,87], respectively); students who reported to belonging to black or brown races were more likely to belong to 'High bullying victimization' class (aOR=3,35; 95%CI = [1,34; 8,37]); low and medium school grades were associated to High bullying victimization and perpetration (aOR=10,12; 95%CI = [4,19; 24,41]) and Moderate bullying victimization (aOR=1,63; 95%CI = [1,17; 2,27]). The results show the need to implement school prevention programs that simultaneously address alcohol use and bullying components, besides taking into account race and gender norms. Key messages Bullying profiles help us to understand how this type of violence happens among students. And the associated factors indicate which groups are at greatest risk and need more attention. The use of alcohol associated with all latent classes, besides showing the impacts of bullying, it also indicates the importance of bullying prevention programs to address substance use prevention.
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