You have accessJournal of UrologyInfections/Inflammation of the Genitourinary Tract: Interstitial Cystitis1 Apr 2012820 FREQUENCY AND DURATION SPECTRUM OF UROLOGIC CHRONIC PELVIC PAIN SYMPTOM FLARES Siobhan Sutcliffe, Graham Colditz, Ratna Pakpahan, David Song, Rebecca Bristol, Vivien Gardner, Gerald Andriole, and H. Henry Lai Siobhan SutcliffeSiobhan Sutcliffe St. Louis, MO More articles by this author , Graham ColditzGraham Colditz St. Louis, MO More articles by this author , Ratna PakpahanRatna Pakpahan St. Louis, MO More articles by this author , David SongDavid Song St. Louis, MO More articles by this author , Rebecca BristolRebecca Bristol Stanford, CA More articles by this author , Vivien GardnerVivien Gardner St. Louis, MO More articles by this author , Gerald AndrioleGerald Andriole St. Louis, MO More articles by this author , and H. Henry LaiH. Henry Lai St. Louis, MO More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.910AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Based on anecdotal clinical evidence, urologic chronic pelvic pain symptom exacerbations, commonly referred to as flares, are believed to occur approximately once a year and last approximately one week. However, no studies, to our knowledge, have investigated the frequency and duration of flares in interstitial cystitis/bladder pain syndrome (IC/BPS) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) patients. Therefore, we conducted a study to describe the spectrum of frequency and duration of flares among IC/BPS and CP/CPPS participants at the Washington University site of the ongoing Multidisciplinary Approaches to the study of chronic Pelvic Pain (MAPP) study. METHODS At their six month study visit, participants were asked to complete an additional form on their frequency and duration of flares, defined as “symptoms that are much worse than usual”. Specifically, they were asked whether they had ever had flares that lasted: 1) less than one hour; 2) more than an hour but less than one day; and 3) more than one day. For each question to which they responded affirmatively, they were also asked to report the average frequency and duration of each type of flare. RESULTS Date, 24 female and 16 male participants have provided information on frequency and duration of flares. The distribution of flares by sex is provided in the table. Table. Distribution of the duration of urologic chronic pelvic pain symptoms flares, Washington University, 2010-11 Female Male No reported flares (%) 0.0 12.5 Duration of flares (%): Only minutes-long 8.3 18.8 Minutes- to hours-long 0.0 6.2 Only hours-long 0.0 12.5 Minutes- to days-long 20.8 6.2 Hours- to days-long 29.2 25.0 Only days-long 41.7 18.8 The distribution of flares appeared to differ by sex (p=0.07), with female participants being considerably more likely to have days-long flares than male participants (91.7 vs 50.0%, p=0.0068). For either sex, minutes-long flares lasted <1-60 minutes and occurred 6 times/day to once every 2 months; hours-long flares lasted 1-23 hours and occurred 3 times/week to 1-2 times/year; and days-long flares lasted 2 days to several months and occurred twice per week to less than once per year. CONCLUSIONS Our findings suggest that there may be a previously unappreciated wide spectrum of frequency and duration of urologic chronic pelvic pain flares that may vary by sex. Future research should investigate the spectrum of symptoms and bother associated with these flares. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e335 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information Siobhan Sutcliffe St. Louis, MO More articles by this author Graham Colditz St. Louis, MO More articles by this author Ratna Pakpahan St. Louis, MO More articles by this author David Song St. Louis, MO More articles by this author Rebecca Bristol Stanford, CA More articles by this author Vivien Gardner St. Louis, MO More articles by this author Gerald Andriole St. Louis, MO More articles by this author H. Henry Lai St. Louis, MO More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...
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