Diphenyl Ether Derivatives Research Articles

Mutagenicity evaluation of diphenyl and diphenyl ether derivatives

Mutagenicity evaluation of diphenyl and diphenyl ether derivatives

ChemInform Abstract: Synthesis and Antiinflammatory/Analgesic Activities of 11H‐Dibenzo‐ (b,e)(1,4)dioxepinacetic Acids.

AbstractThe diester (I) is coupled with (II) to produce the diphenyl ether derivative (III) which is reduced to (IVa) and then transformed into thebromides (IVb) and (IVc).

Localization of electron transport inhibition in plastoquinone reactions.

Reduction kinetics of P700 following a short flash are measured in spinach chloroplasts after oxidation of the electron carriers between the two photoreactions by far-red light. Three features of the kinetics allow us to localize simultaneously inhibition at different sites between photoreaction II and the reducing site of plastoquinol. These are the initial lag, the halftime and the area under the transient of the P700 absorbance change, which indicate the electron transfer time from photoreaction II to the reducing site of plastoquinol, the rate of plastoquinol oxidation, and the number of electrons transferred to the special plastoquinone B functioning as secondary electron acceptor of photosystem II, respectively. As an additional diagnostic parameter for inhibition before and after the plastoquinone pool, the area under the transient of the P700 absorbance change is used after long flashes. This area is proportional to the amount of reduced plastoquinone as shown by the absorbance change at 265 nm. The effects of 3-(3',4'-dichlorophenyl)-1,1-dimethylurea (DCMU) and 2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone (DBMIB) are compared with those of 2-bromo-4-nitrothymol, 2,4-dinitrophenyl ether of 2-iodo-4-nitrothymol, and Illoxan as representatives for new classes of inhibitors. While 2-halogeno-4-nitrothymols inhibit the reduction of plastoquinone similarly to DCMU, their diphenyl ether derivatives inhibit selectively the oxidation of plastoquinol.

Identification of CNP, Chlomethoxynil and TCNP in Corbicula

Three unknown peaks were found on ECD gaschromatograms of n-hexane extracts from corbicula, appearing closely after organochlorine pesticides.These three substances were purified by silver nitrate-coated florisil column chromatography and high performance liquid chromatography. Two of them were identified as CNP (2, 4, 6-trichrophenyl-4′-nitrophenyl ether) and chlomethoxynil (2, 4-dichlorophenyl-3′-methoxy 4′-nitrophenyl ether) which are widely used as rice paddy herbicides in Japan.The other constituent was suspected from its mass spectrum to be a diphenyl ether derivative with four chlorine atoms and a nitro group. Later, it was identified as a TCNP (2, 3, 4, 6-tetrachlorophenyl-4′-nitrophenyl ether), as a result of two synthetic reactions; 1) chlorination of CNP and 2) a coupling reaction on 2, 3, 4, 6-tetrachlorophenol and 1-fluoro-4-nitrobenzene.TCNP is present in commercial CNP herbicide, and is presumably a byproduct of CNP synthesis.

Studies on diphenyl ether derivatives. X. Pharmacological screening of dibenzo[b,g][1,5]thiazocine oxide derivatives (author's transl)

Pharmacological screening was carried out on newly synthesized dibenzo[b, g][1, 5]thiazocine dioxide derivatives, chiefly for their central nerve action. In the observation of general behavior of rats and mice, these compounds hardly showed a tendency for central nerve suppression, and showed no effect on the grooming to tactile stimuli and acetic acid induced writhing. Anti reserpine activity was seen in a considerable number of the compounds but this activity was fairly weak. Anti tremorine action was seen in a number of these compounds, ED50 values of anti tremorine tremor effect of six compounds with strong activity were measured and the values were compared with those of other anti-parkinsonism drugs. Three compounds with especially strong activity were submitted to LD50 measurements.

ChemInform Abstract: VIBRATIONAL SPECTRA AND CONFORMATION OF MOLECULES OF DIPHENYL ETHER AND ITS DERIVATIVES AT LIQUID NITROGEN TEMPERATURE

Chemischer InformationsdienstVolume 6, Issue 6 Physical Organic Chemistry ChemInform Abstract: VIBRATIONAL SPECTRA AND CONFORMATION OF MOLECULES OF DIPHENYL ETHER AND ITS DERIVATIVES AT LIQUID NITROGEN TEMPERATURE M. HORAK, M. HORAKSearch for more papers by this authorR. JOSEFI, R. JOSEFISearch for more papers by this author M. HORAK, M. HORAKSearch for more papers by this authorR. JOSEFI, R. JOSEFISearch for more papers by this author First published: February 11, 1975 https://doi.org/10.1002/chin.197506064AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume6, Issue6February 11, 1975 RelatedInformation

Studies on Diphenyl Ether Derivatives. VIII. NMR Spectra and Conformational Structure of Dibenz[b, g][1, 5]oxazocine and Thiazocine Derivatives and Their Mass Spectra

The NMR spectra of 6-substituted 6, 7-dihydro-5H-dibenz[b, g][1, 5]oxazocine and thiazocine derivatives (1) and the sulfoxides or sulfones (6) and the bimolecular sixteen membered ring compounds (2) were reported. The methylene protons at 5 and 7-position of the ring of 6 appeared as a AB system quartet. All ring methylene protons in 2 gave a singlet. The temperature dependent coalescence and splitting of the singals was observed in 1. At low temperature the 5, 7-methylene protons in thr ring of 1 gave a AB quartet and a singlet. From these facts it was suggested that 1 was amixture of the conformational isomer A and B in Fig. 8 and they could not freely rotate each other even at room temperaute. 6 existed only as the structure A. The Mass spectra of them were also reported.

Studies on diphenyl ether derivatives. VI. Synthesis of dibenz(b,g)(1,5)thiazocine oxide derivatives (author's transl)

Studies on diphenyl ether derivatives. VI. Synthesis of dibenz(b,g)(1,5)thiazocine oxide derivatives (author's transl)

Studies on diphenyl ether derivatives. V. Synthesis of dibenz(b,g)(1,5)thiazocines (author's transl)

Studies on diphenyl ether derivatives. V. Synthesis of dibenz(b,g)(1,5)thiazocines (author's transl)

Studies on antiseptics for foodstuff. LXXII. Studies on diphenyl ether derivatives, biphenyl derivatives and dibenzofuran derivatives as a preservative for sake

Studies on antiseptics for foodstuff. LXXII. Studies on diphenyl ether derivatives, biphenyl derivatives and dibenzofuran derivatives as a preservative for sake

Phenol oxidation mechanisms. A search for phenoxylium intermediates

Results which point to the occurrence of an ionic intramolecular coupling process in the oxidation of certain diphenyl ether and diphenylmethane derivatives are described. This process is in contrast to the usual free-radical coupling route encountered under different conditions. An attempt to induce a related heterolytic intramolecular coupling during the oxidation of some bis-hydroxynaphthylmethane monoethers was unsuccessful.

Structural peculiarities of some diphenyl ether derivatives

On bromination of diphenyl ether the first bromine atom enters into the hydrocarbon ring, and the second bromine atom enters into the ethereal ring. The same principle was found for the chloromethylation of diphenyl ether.

Phenol Oxidation of Isoquinoline Alkaloids. II. Oxidative Coupling of dl-N-Methylisosalsoline

Oxidative coupling of dl-N-methylisosalsoline (III) with potassium ferricyanide was carried out, and the structures of the products were determined. It was found that III gives rise both to biphenyl derivatives (VI, VII) and diphenyl ether derivative (IV), and a steric participation of 1-substituent of 2-methyl-6-methoxy-7-hydroxy-1, 2, 3, 4-tetrahydroisoquinoline derivative in the product development in the phenol oxidation reactions was observed.

Quinoline derivatives. (13). Antifungal activity of quinoline derivatives, azocompound, and diphenylether derivatives

With 80 kinds of thiocyanic derivatives, having been synthesized so far, the pot test against rice blast disease was examined and the correlation between chemical structures and antibacterial activities was studied. Some of the effective compounds were further examined by the field test and the results were described.

Syntheseversuche in der Griseofulvinreihe. 3. Mitteilung. Eine neue Ringöffnung bei Dehydrogriseofulvin

Abstract(−)‐Dehydrogriseofulvin (I) is converted to the diphenylether derivatives IV or VIII, respectively, by action of a base or an acid. The mechanism of the basic ring opening reaction has been established by use of 14C labelled methanol. In the case of the epimerisation of griseofulvin (II) under the influence of methylate, however, it is shown that a more complicated mechanism is involved.

Built in Fire Protection using....Diphenyl Ether Derivatives in Condensation Polymers

Built in Fire Protection using....Diphenyl Ether Derivatives in Condensation Polymers

芳香族エーテル化合物の赤外部吸収スペクトル (第1報)

Infrared absorption spectra of 26 kinds of diphenyl ether derivatives, including dimethyldiphenyl, dinitrodiphenyl, and nitrochlorodiphenyl ethers, were measured in the region of 4000 to 660cm-1 and characteristic absorption bands for C-O-C bond were examined. There is a strong absorption band in the region of 1256-1238cm-1, considered to be due to asymmetric stretching vibration of C-O-C. Effect of nitro and chloro radicals on this absorption maximum is not so marked while the maximum is seen in a higher wave-number side in m-methyl substituents. As other characteristic bands, a medium absorption is observed in the region of 952-935cm-1 in diphenyl ether derivatives possessing a m-methyl or a m-nitro group, and in the region of 909-851cm-1 in other derivatives. Assignment of this absorption band is not clear but it may possibly be that of a symmetric stretching vibration of C-O-C. Examinations were also made on characteristic bands, other than the above, in the region of C-H out-of-plane vibrations.

Diphenyl Ether誘導体に於けるFriedel-Crafts反応 (第8報)

Diphenyl Ether誘導体に於けるFriedel-Crafts反応 (第8報)

Diphenyl Ether誘導体に於けるFriedel-Crafts反応 (第10報)

Diphenyl Ether誘導体に於けるFriedel-Crafts反応 (第10報)

Diphenyl Ether誘導体の赤外線吸収スペクトル

Diphenyl Ether誘導体の赤外線吸収スペクトル