Differences In Hb Levels Research Articles

Evaluation of Immuno-Hematological Parameters of Severe and Mild COVID-19 Cases in Babylon Province, Iraq

The hematopoietic system plays a very important role in contracting the corona virus infection. Hematology indicators are among the factors related to the clinical results of patients with covid-19 due to their cost-effectiveness, availability, speed and convenience of testing. The aim of this study was comparing hematological parameters including the number of Red Blood Cells (RBC), hemoglobin, hematocrit, and platelet count among mild and severe COVID-19 patients. Methods: The study was conducted on 100 Iraqi patients COVID-19 patients. Subjects were classified into two groups with mild (n= 50) and severe (n=50) COVID-19 infection symptoms based on the clinical criteria. The hematological parameters measurement included Red Blood Cell (RBC) count, Hemoglobin (Hb) levels, White Blood Cell (WBC) count, Platelet count (PLT), Hematocrit (HCT) levels, Platelet Distribution Width (PDW), and Mean Platelet Volume (MPV). An independent sample T-test was used to compare the means of hematological parameters between two groups. Results: The RBC count was significantly lower in severe group compared to mild group (P ≤ 0.05). HCT levels were significantly reduced in the severe group compared to mild group (P ≤ 0.05). The severe patients had a significantly lower PLT than mild patients (P ≤ 0.05). No significant difference in Hb levels was observed between severe and mild patients. The severe patients had a significantly higher PDW than mild patients (P ≤ 0.05). Additionally, the severe patients had a significantly higher MPV than mild patients (P ≤ 0.05). Conclusion: The findings of this study indicate that complete blood count measurements can be used as useful biomarkers to assess the severity of Covid-19. Early identification of severe COVID-19 patients using these markers can help to better manage and accelerate the treatment process for COVID-19 patients.

Improvement of Hemoglobin Levels in Pregnant Women with Anemia Through Dragon Fruit Consumption

Anemia frequently manifests in pregnant women as a consequence of alterations in the cardiovascular system, leading to hemodilution and a subsequent decline in blood oxygen levels. The augmented iron demands during pregnancy arise from the needs of the fetus and placenta, coupled with physiological shifts like heightened blood volume and red blood cell count. This elevation in levels may contribute to diminished hemoglobin and hematocrit levels, consequently escalating the prevalence of anemia and iron deficiency during pregnancy. A viable solution for averting anemia in pregnant women involves the consumption of fruits rich in iron and vitamin C, such as dragon fruit, crucial for hemoglobin synthesis. The research method employed in this study followed a quantitative approach, specifically utilizing quasi-experimental research with a pretest-post-test design, including a control group. The study population comprised all pregnant women attending TPMB N Depok, West Java, during October-December 2023. Inclusion criteria involved pregnant women aged 16-34 weeks who visited TPMB N and exhibited signs of anemia. The study sample consisted of pregnant women willing to consume 200 cc of dragon fruit juice daily for a duration of 14 days. Bivariate data analysis was conducted using the Mann-Whitney Test. The intervention implemented involved administering dragon fruit juice, prepared by blending 200g of dragon fruit with 200cc of water and adding 3 tablespoons of sugar. The findings reveal a statistically significant difference in Hb levels among pregnant women before and after the consumption of dragon fruit juice, with a P value of 0.001.

Differences in Hemoglobin Levels 6 Hours and 24 Hours After Packed Red Cells Transfusion

The hemoglobin examination instructed by Dr. Sardjito General Hospital attending doctors was 6 hours after the PRC transfusion. It is recommended that a hemoglobin examination be carried out 24 hours after transfusion to determine the patient's hemoglobin after complete equilibrium occurs. This study aimed to determine the mean increase in Hb levels 6 hours and 24 hours after PRC transfusion and to examine the difference in Hb levels 6 hours and 24 hours after PRC transfusion, respectively, compared with baseline Hb levels in non-hematological malignancy patients. This prospective analytic observational study examined hemoglobin at 6 hours and 24 hours after PRC transfusion. The differential test between delta Hb levels 6 hours after PRC transfusion compared to baseline Hb levels and delta Hb levels 24 hours after PRC transfusion compared to baseline Hb levels were analyzed using paired T-test. There was a statistically significant difference between baseline Hb levels and Hb levels 6 hours after PRC transfusion (p<0.0001) and a statistically significant difference between baseline Hb levels and Hb levels 24 hours after PRC transfusion (p<0.0001). The differential test between delta Hb levels 6 hours after PRC transfusion compared to baseline Hb levels and delta Hb levels 24 hours after PRC transfusion compared to baseline Hb levels obtained a statistically significant difference (p=0.0024). The mean increase in hemoglobin was 1.76+0.78 g/dL 6 hours after PRC transfusion and 1.9+0.78 g/dL 24 hours after PRC transfusion. There were differences in delta Hb levels 6 hours and 24 hours after PRC transfusion, respectively, compared with baseline Hb levels in non-hematological malignancy patients, which were statistically significant but not clinically significant.

The effect of the family empowerment model on the ability to managing diet and increasing hemoglobin in pregnant women

Anemia often occurs due to iron deficiency because, in pregnant women, there is a doubling of an iron requirement to meet the mother's needs in preventing blood loss during childbirth and fetal growth. Therefore, anemia in pregnant women must be prevented so that the fetus can grow and develop properly. This study aimed to determine the effect of the family empowerment model on the ability to manage diet and increase hemoglobin (Hb) levels in pregnant women with anemia. The research design was quasi-experimental, conducted at the Langsa Baro Health Center work area in 2018. The sample comprised 30 pregnant women divided into two groups, namely 15 women who received intervention and 15 who did not. Sampling was performed using the purposive sampling technique, and data were collected through direct interview techniques with questionnaire instruments. Data processing was performed by statistical analysis using a Paired T-test test with a significance level of 95% CI. The results showed differences in Hb levels, knowledge, and attitudes before and after family empowerment (p <0,05). In conclusion, there was a significant effect on the ability to manage diet and increase hemoglobin (Hb) levels in pregnant women with anemia.

Perioperative Blood Management Programme in Jehovah’s Witnesses Undergoing Total Hip Arthroplasty

Total hip arthroplasties aim to improve quality of life and reduce pain in patients suffering from late-stage hip osteoarthritis. On the other hand, it may represent a risky surgical procedure in people who refuse blood products because of religious beliefs, such as Jehovah’s Witnesses (JW). Preoperative optimisation protocols of these patients allow medical professionals to perform arthroplasties in a safer manner, avoiding allogeneic blood transfusion. In our retrospective study, two groups of patients were evaluated. Group 1 included JW patients who underwent a preoperative Hb optimisation program; Group 2 included non-JW patients authorizing transfusion in case of necessity. Differences in Hb levels were as follows: before surgery (JW 14.24 ± 1.10 vs. non-JW 12.48 ± 1.00, p-value ≤ 0.05), and after surgery (day 1 Hb: JW 12.88 ± 0.90 vs. non-JW 10.04 ± 1.30, p-value ≤ 0.05; day 3 Hb: JW 14.65 ± 0.80 vs. non-JW 9.10 ± 0.90 p-value ≤ 0.05). Moreover, cost-effectiveness strategies were evaluated in both groups. Our findings support that patient blood management programs are a safe and good strategy in hip prosthetic surgery, decreasing risks and transfusion overuse.

Perioperative blood management programme in Jehovah’s witnesses undergoing total knee arthroplasty: clinical results and cost-benefit analysis

Introduction Total knee arthroplasties have the purpose to improve quality of life from joint-related pain. On the other hand, it may represent a risky surgical procedure in people who refuse blood products due to their religious beliefs, such as Jehovah’s Witnesses (JW). Preoperative optimization protocols of these patients allow performing arthroplasties in a safer manner avoiding allogeneic blood transfusion. Methods In our retrospective study, 2 groups of patients were evaluated. Group 1, included JW patients who underwent a preoperative Hb optimisation programme; group 2 included non-JW patients authorizing transfusion in case of necessity. Results Differences in Hb levels were: before surgery (JW 13,63±1,26 vs. non-JW 12,83±1,21, p-value=0,22), after surgery (day 1 Hb: JW 12,26±1,47 vs. non-JW 10,88±1,87, p-value=0,1; day 3 Hb: JW 10±2,97 vs. non-JW 9,23±1,07 p-value=0,64). In the JW group the mean Hb concentration decreased from 13,63±1,26 g/dL preoperatively to 12,26±1,47 g/dL (day 1) while in non-JW group fell from 12,83± g/dL to 10,88± g/dL. There was no statistically-difference between the 2 groups. Moreover, cost-effectiveness strategies were evaluated in both groups. Conclusion Our findings support that PBM programs represent a safe and good strategy in knee prosthetic surgery, decreasing costs, risks and transfusion overuse.

Comparison between the influence of roxadustat and recombinant human erythropoietin treatment on blood pressure and cardio-cerebrovascular complications in patients undergoing peritoneal dialysis.

Roxadustat treatment in PD patients is equivalent to ESAs in increasing hemoglobin (Hb). But blood pressure, cardiovascular parameters, cardio-cerebrovascular complications and prognosis in the two groups before and after treatment has not been sufficiently discussed. Sixty PD patients who were treated with roxadustat for renal anemia in our PD center recruited from June 2019 to April 2020 as roxadustat group. PD patients treated with rHuEPO were enrolled at a 1:1 ratio as rHuEPO group using the method of propensity score matching. Hb, blood pressure, cardiovascular parameters, cardio-cerebrovascular complications and prognosis were compared between the two group. All patients were followed up for at least 24 months. There were no significant differences in baseline clinical data or laboratory values between roxadustat group and rHuEPO group. After 24 months of follow-up, there was no significant difference in Hb levels (p > 0.05). There were no significant changes in blood pressure, or the incidence of nocturnal hypertension before and after treatment in roxadustat group (p > 0.05), while blood pressure significantly increased in rHuEPO group after treatment (p < 0.05). Compared with roxadustat group after follow-up, rHuEPO group had a higher incidence of hypertension, the levels of cardiovascular parameters were worse and cardio-cerebrovascular complications had a higher incidence (p < 0.05). Cox regression analysis showed age, systolic blood pressure, fasting blood glucose, and rHuEPO use before baseline were risk factors for cardio-cerebrovascular complications in PD patients, while treatment with roxadustat was a protective factor for cardiovascular and cerebrovascular complications. Compared with rHuEPO, roxadustat had less influence on blood pressure or cardiovascular parameters, and it was associated with a lower risk of cardio-cerebrovascular complications in patients undergoing PD. Roxadustat has a cardio-cerebrovascular protective advantage in PD patients with renal anemia.

Analysis of Pharmacist Intervention in Anaemic Pregnant Women in Stunting Prevention

Accelerating stunting reduction is a national priority in realizing healthy, intelligent and productive human resources. Multi-dimensional factors cause stunting, so multi-sectors are responsible for handling it. To optimize stunting prevention, health workers such as pharmacists have an essential role to play. As part of change agents and competence, pharmacists should optimize their role in providing information and education and as caregivers. Pharmacists are expected to play a role in diet and nutrition management, increasing adherence to therapy, and monitoring drug side effects in pregnancy. This study aims to get an overview of the effect of pharmacist intervention in preventing anaemia in pregnant women in supporting the treatment of stunting. This type of research was a quasi-experimental study with a cohort study design before and after the intervention was carried out on anaemic pregnant women receiving blood supplement therapy in Pandeglang District, Banten Province. The clinical outcome assessment was measured based on the Hb value and the pregnant woman's weight. The level of adherence was assessed using the Medication Adherence Report Scale (MARS-5). The results showed increased adherence to using Iron Tablets after pharmacist intervention (99.47%). The MARS-5 score showed an average increase of 24.99 ± 0.07. The average patient's Hb increased after the intervention and showed a significant difference in Hb levels (p&lt;0.05). The decrease in the number of patients with anaemia in pregnant women reached 91.8%. Pregnant women's weight increased monthly, showing a significant difference (p &lt;0.05). Based on these results, it can be concluded that there was a significant increase in adherence to the consumption of Blood Supplement Tablets, Hb levels, and body weight in pregnant women after pharmacists intervened in Pandeglang Regency, Banten Province.

Perbandingan Kadar HB Sebelum dan Sesudah Pengobatan Oat Fase Intensif pada Penderita Tuberkulosis Paru di Puskesmas Petanahan Kebumen Tahun 2021

Treatment of tuberculosis with main anti-tuberculosis drugs (OAT) includes isoniazid (INH), rifampin (RIF), ethambutanol (EMB), streptomycin (SM), and pyrazinamide (PZA). Although most Anti-Tuberculosis Drugs (OAT) are acceptable in therapy, they have potential side effects, including the side effects of hematological reactions such as anemia. This study's purpose was to compare HB levels before and after the intensive phase of Anti-Tuberculosis Drugs treatment in TB patients at Petanahan Public Health Care Center, Kebumen Regency. This was an analytic observational study with a cross-sectional design. The sample in this study was 28 people. The result showed that the average Hb level of pulmonary TB patients at Petanahan Public Health Care Center before and after the treatment were 11.05 g/dl and 11.6 g/dl, respectively. Therefore there was an effect of comparing Hb levels before and after the intensive phase of Anti-Tuberculosis Drugs treatment in pulmonary TB patients at the Petanahan Public Health Center in 2021. The increase in the average Hb levels of patients with pulmonary TB before and after the treatment was 0.55. The sig values obtained from the analysis of Hb levels before and after the treatment were a = 0.200 (p0.005) and 0.023, respectively. Due to the P value (0.023 &lt; 0.05), Ho was rejected. It meant that there was a difference in Hb levels before and after the Intensive Phase of Anti-Tuberculosis Drugs treatment in patients with pulmonary TB at Petanahan Public Health Care Center, Kebumen Regency.

The impacts of hypoxia-inducible factor stabilizers on laboratory parameters and clinical outcomes in chronic kidney disease patients with renal anemia: a systematic review and meta-analysis.

Renal anemia in chronic kidney disease (CKD) is associated with poor outcomes. Hypoxia-inducible factor (HIF) stabilizer, which induces endogenous erythropoietin synthesis and enhances iron mobilization, is a novel treatment for anemia in CKD. We conducted a systematic review and meta-analysis to analyze the effect of HIF stabilizers in anemic CKD patients. This meta-analysis included 43 officially published articles and 3 unpublished studies (27 338 patients). HIF stabilizer treatment significantly increased hemoglobin (Hb) level when compared with placebo (mean difference 1.19g/dL; 95% confidence interval 0.94 to 1.44g/dL; P<.001). There was no significant difference in Hb level when compared with erythropoiesis-stimulating agents (ESAs). Significant reductions of ferritin and transferrin saturation (TSAT) were observed, while total iron-binding capacity was increased in the HIF stabilizer group compared with placebo or ESAs. HIF stabilizers significantly reduced hepcidin, high-density lipoprotein, low-density lipoprotein and triglyceride levels. Acute kidney injury and thrombotic events were significantly observed in patients receiving HIF stabilizers. There were no significant differences in myocardial infarction, stroke, dialysis initiation, pulmonary hypertension and mortality between HIF stabilizer and control groups. The present meta-analysis provided evidence that HIF stabilizers increased Hb and TIBC levels and reduced hepcidin, ferritin and TSAT in CKD patients with renal anemia. Long-term follow-up studies on clinical outcomes of HIF stabilizers are still needed.

The Effect of The Combination Juice of Guava and Red Spinach on The Hemoglobin Level of Pregnant Women on Third Trimester in Health Center of Melak

Introduction: Indonesia is a developing country that has a very high prevalence of anemia in pregnancy. The results of the Riskesdas data show that pregnant women experiencing anemia in Indonesia increased from 37.1% to 48.9%. Anemic pregnant women have difficulty, and bleeding during childbirth. Meanwhile, babies are at risk of being born LBW. Objective: The purpose of this study was to determine the effect of giving a combination of red guava juice and red spinach on the Hb levels of pregnant women in the third trimester in the working area of the Melak Health Center. Methods: This study uses a quantitative approach, quasi experiment with Non-Equivalent Control Group Design. Resultand Discussion: The results showed that there were differences in the Hb levels of respondents between the intervention and control groups after being given the research intervention (p-value = 0,000). There was a difference in Hb levels of pregnant women in the third trimester in the intervention group between before and after being given the research intervention. Conclusion: It is expected that pregnant women can increase the intake of vegetables that are high in iron and vitamin C such as guava and red spinach, as an effort to prevent and overcome anemia in pregnancy

Effect of Garlic (Allium Sativum) Extract on Hemoglobin Levels in Chronic Hemodialysis Patients

CKD patients undergoing hemodialysis have increased inflammatory biomarkers. Anemia in CKD is associated with an advanced degree of inflammation while undergoing chronic hemodialysis. Garlic (Allium sativum) has anti-inflammatory and antioxidant effects, which are expected to improve the degree of inflammation in CKD patients. This study aims to assess the effect of garlic extract on hemoglobin levels in patients undergoing chronic hemodialysis. This study was an experimental study with a double-blind, randomized clinical trial design. This study was a crossover, randomized, placebo-controlled, double-blind trial. The study subjects were 40 stages 5 CKD patients undergoing chronic hemodialysis, randomly divided into two groups, namely the group that received 1000 mg of garlic extract per day (2x500 mg) for six weeks and the group that received a placebo, then a 2-week wash-out period. And after that, the two groups were given alternate treatment. Statistical analysis was carried out using the SPSS version 25.0 program. A total of 40 subjects participated in the study, 57.5% male. The mean age of the subjects was 48.6 (26-59) years. The results showed that there was a significant difference in Hb levels in the garlic group (p = 0.047), where the increase in Hb was from 10.2 (9.2–11.8) mg/dl to 10.23 (8.9–11.6) mg/dl while in the placebo group, there was a decrease in Hb from 10.18 (9.6 – 11.2) mg/dl to 10.05 ± 0.52 mg/dl. Garlic extract can reduce levels of inflammation which can then increase hemoglobin levels.

Kadar Hb dan Perubahan Berat Badan Tikus Wistar Model Anemia Defisiensi Besi Setelah Pemberian Minyak Ikan Patin

Anemia is a health problem with little progress in its management, even thoughthe global prevalence of anemia is relatively high. Anemia due to iron deficiency affectsweight gain in children. Giving catfish oil to anemic rats was done to see the effect onHb levels and body weight.This research is a true experiment with a randomized pre-post-test design witha control group. Male Wistar rats were divided into four groups, namely K- (rats fedstandard), K+ (rats fed standard without iron), P1 (rats fed standard without iron,getting catfish oil 0.039 ml/day), P2 (rats fed standard without iron, supplemented withferrous sulfate 0.126 mg/day) for 14 days. Hb levels were measured before and aftertreatment using the ELISA method. The rats were weighed every day.Paired t-test was conducted to determine differences in Hb levels and changesin body weight before and after the intervention. In addition, the Anova test followedby Post Hoc Bonferroni was carried out to analyze the difference in effect on the fourgroups.There were significant differences in body weight changes before treatment and aftertreatment (p=0.00, p&lt;0.05) on K-(13 gram ± 0.81), K+(5.5 gram ± 1.04), P1 (12 grams± 0.7), P2 (13 grams ± 0.63). In addition, the study showed a significant increase inHb levels before and after treatment (p=0.00, p&lt;0.05) at P1(4.7 g/dL ± 0.76) andP2(5.13 g/dL ± 0.15 ), as well as a decrease in K- (0.09 g/dL ± 0.19) and K+ (0.37g/dL ± 0.18).There was an effect of giving catfish oil on Hb levels and changes in bodyweight, which increased significantly in iron deficiency anemia Wistar rats.Keyword: body weight, catfish oil, Hb levels iron deficiency anemia

Potential and challenge assessment of tannin extracts from black tea in male rabbits fed contaminated diet by Mycotoxins

Abstract The focus of this research was to investigate how tannin extract from black tea influenced the hematological and histopathological evaluations of male rabbits fed a mycotoxin-contaminated feed, including 17 ppb aflatoxin, 5 ppb ochratoxin and 2 ppb fumonisin. A total of 28 local male rabbits were allocated into four groups, the first of which was a control group. The second was fed a Mycotoxin-contaminated meal. The third was given a Mycotoxin feeding with tannin extracts (125mg/mL per head) administered orally, while the fourth was fed a Mycotoxin contaminated diet with tannin extracts (250 mg/mL per head) given orally. The findings revealed that tannin extracts seemed to have a significant positive impact on haematological results, particularly RBCs and WBCs, throughout the period; however, the 250 mg/mL dose showed no significant differences in Hb levels. Nonetheless, as compared to the Mycotoxin group, the histopathological sections of tannin extract demonstrated a reduction in the toxicity of the Mycotoxin diet on the liver and kidney tissues; conversely, the tissue sections of the control animals showed no abnormalities. In male rabbits fed contaminated Mycotoxin diets, tannin extract from black tea was found to have a favourable impact on hematological activities and vital organs such as the liver and kidney.

Compatibility of Two EDTA Tubes for Hemoglobin (Hb) Hematocrit (Hct) Tests with Aptus Equipment

Routine Hemoglobin (Hb) and Hematocrit (Hct) tests are done with the Sysmex XN 1000 device at the Central Laboratory of Dr. Soetomo General Hospital. Aptus POCT can be used quickly and practically for rapid Hb and Hct tests. Intherma EDTA tubes are usually used to substitute the empty supply of Greiner EDTA tubes for blood sampling. This study aims to analyze Hb and Hct levels from blood samples in Greiner and Intherma EDTA tubes which are measured using Aptus and Sysmex devices, as well as analyze their correlation. This study is a descriptive analytic study with general check-up outpatients in Dr. Soetomo General Hospital since January until May 2020 as the research subjects (n = 50). Research variables consist of Intherma tubes, Greiner tubes, Hb and Hct. Statistical analysis was performed to compare Hb, Hct values using Intherma tubes and Greiner tubes which used Aptus and Sysmex XN 1000 devices. Results revealed that mean Hb value using Greiner tubes and Sysmex device was 13.73 ± 1.39, mean Hb value using Greiner tubes and Aptus device was 12.9 ± 1.1, mean Hb value using Intherma tube and Sysmex device was 13.9 ± 1.513 and mean Hb value using Intherma tube and Aptus device was 13.00 ± 1.112. Adjustments are required for the Aptus device, which still uses basic methods unlike the Sysmex XN 1000 device which is a reference value. In conclusion, there is a significant difference in Hb levels measured using Sysmex and Aptus devices. There is also a significant difference in Hct levels measured using Greiner and Intherma EDTA tubes.

EFEKTIFITAS PEMBERIAN COKLAT KELOR (Kokoa Moringa Oleifera) TERHADAP KADAR HEMOGLOBIN REMAJA PUTRI

Iron deficiency anemia is still a major nutritional problem in adolescents in Indonesia. One of the efforts to handle it is by giving Moringa chocolate. Research objective: analyzeeffectiveness of giving Moringa chocolate on hemoglobin levels of adolescent girls. Research method: Type of researchquasi experiment with nonrandomized pretest and posttest design with control group. The population of this study was 75, purposive sampling with a sample of 60 which were divided into a treatment group of 30 people, and a control group of 30 people. The control group consumed 50g of Moringa chocolate for 30 consecutive days, and the control group did not consume Moringa chocolate. Hb levels were measured before and after treatment. Data analysis used paired t-test and independent t-test. Results: Paired t-test in the treatment group p value of 0.009 (p &lt;0.05),CI95%, which means there is a difference in Hb levels before and after being given Moringa chocolate, while in the control group the p value is 0.255 (p&gt;0.05) 95% CI, which means there is no difference in Hb levels in the control group who are not given Moringa chocolate. . Independent analysis of t-test obtained p value of 0.005 (p &lt;0.05), which means that there is a significant effect on the measurement results of post-test HB levels between the treatment group and the control group. Conclusion: Moringa chocolate affects young women's Hb levels.

THE EFFECT OF DATE FRUITS (PHOENIX DACTYLIFERA L) INTERVENTION TO INCREASE HEMOGLOBIN LEVELS IN FEMALE ADOLESCENTS

Background. Anemia is one of the common health problems globally, where a condition of red blood cells is inadequate to meet the physiological needs caused by iron deficiency. The short term impact of anemia on adolescents can cause growth disorders, while the long term impact on pregnant women can cause pregnancy and childbirth complications. Date fruit is one of the fruits that containing iron (Fe), vitamin C, vitamin B complex, and folic acid that can help form red blood cells. Consuming the date fruits may improve formation of red blood cells and prevent anemia. Objective. To determine the effect of the intervention of date fruits in increasing hemoglobin levels among female adolescents at Islamic boarding school. Method. This research was performed using a pre-experimental study with one group pretest and posttest design. The sampling method in this research used purposive sampling with samples of 30 female adolescent students aged 15–18 years old at Modern Islamic Boarding School (Pondok Modern Gontor Putri 2), Ngawi, East Java, Indonesia. The inclusion criteria was adolescent suffering from anemia (age 15 until 18 years, Hb &lt;12 g/dL, not menstruation during intervention). The intervention was carried out for seven days by giving seven date fruits (50 g) per day. Hemoglobin levels had recorded before and after intervention. The data were analyzed using paired t-test. Results. The median hemoglobin (Hb) level before giving date fruits was 10.8 g/dL and the median Hb level after giving date fruits was 11.9 g/dL. There were differences in Hb levels before and after giving date fruit in the treatment group (p=0.001). Conclusion. The intervention of consuming seven date fruits (50 g) for seven days effectively increased hemoglobin level.

Impact of Anthelmintic Treatment on the Burden of Helminth Infections in Primary Schoolchildren in Biyela Health Zone in Kinshasa, Democratic Republic of the Congo

Background: The study evaluated the impact of anthilminthic treatment, given as non-investigational drugs, on helminth infections, anaemia, and hemoglobin (Hb) level in the context of a malaria clinical trial in which Sulfadoxine Pyrimethamine (SP) and SP+Piperaquine (PQ) were also evaluated as an intermittent preventive treatment strategy in schoolchildren in the Democratic Republic of Congo (DRC). Methods: In a nested cohort study, 616 malaria asymptomatic children attending primary schools of Biyela health area were enrolled and follow-up from November 2012 to November 2013. The control group for the nested study was the negative on helminth infections. They received one dose of PZQ and ALB at baseline and then 2 doses of ALB at 4 months intervals. During the 12-months of follow-up, stool and urine samples were collected for helminth infections and finger prick blood for Hb level. Paired test analyses were used to compare the status before and after treatment, and confounding variables for Hb level were tested by multiple linear regression analysis. Results: At baseline, the prevalence of helminth infections and anaemia were 39.2% (95% CI: 34.7-43.7), and 41.8% (95% CI: 37.3-46.3), respectively. Mean Hb level was 11.6g/dl (SD±1.3). After 12-months post-anthelminthic treatment, the prevalence of helminth infections reduced to 7.2% (p&lt;0.001). There was no change in Hb level and anaemia in the control which received only the anthelminthic drug (p=1.00 and p=0.26, respectively) at 12-months postintervention, compared to those who received active antimalarial SP (p=0.02 and p=0.09, respectively) and PQ (p=0.01 and p&lt;0.001, respectively). Similarly, no difference in Hb level was observed among the infected and uninfected schoolchildren with helminths at 12-months after anthelminthic treatment. Conclusion: These findings suggest that anthelminthic treatment reduces significantly the prevalence of helminth infections. There was no impact on anaemia and Hb level due to the use of anthelmintic drugs.

The Effectiveness of Fried Catfish Cake In Increasing Hemoglobin Levels And Oxygen Saturation In Blood In Pregnant Women

&lt;p&gt;Iron deficiency anemia mainly affects pregnant women, lactating women and women of childbearing age in general. Many things change in pregnant women in the third trimester of pregnancy. In the third trimester, blood volume is still increasing so pregnant women need foods rich in iron and vitamin C for good iron absorption. Catfish is one of the foodstuffs that is easy to serve and the price is cheaper than other fish. The nutritional content of catfish will increase with the right way of processing. Fresh catfish contains 1.0 mg of iron. After frying, it becomes 1.2 mg. With the condition of pregnant women who are prone to anemia, pregnant women must fulfill their nutrition by adding additional food, which can be in the form of snacks made from catfish so that their fe needs will be met. Catfish, apart from being processed into meatballs, can also be processed into the fried catfish cake. Quasi-experimental research type &lt;em&gt;non randomized pre test post test&lt;/em&gt;. The research subjects were pregnant women in the third trimester. The analysis of this study used the &lt;em&gt;Paired t test&lt;/em&gt;. Results: the results of research that has been conducted regarding differences in Hb levels in pregnant women in the third trimester before and after being given fried catfish cake, it was found that there were differences in Hb levels before and after treatment, this result was evidenced by the results of the t statistical test where the t&lt;em&gt;count&lt;/em&gt; was 10,816 with a significance level of ρ&lt;em&gt;&lt;sub&gt;value&lt;/sub&gt;&lt;/em&gt; of 0.000, there is a significant difference because ρ&lt;em&gt;&lt;sub&gt;value&lt;/sub&gt;&lt;/em&gt; is smaller than α (0.05). Meanwhile, for oxygen saturation with the Wilcoxon test statistic, the Z value is -3.345 with a significance level of ρ&lt;em&gt;&lt;sub&gt;value&lt;/sub&gt;&lt;/em&gt; of 0.001, Thus before and after treatment there is a significant difference because the value is smaller than α (0.05). The brain of fried catfish cake is effective in increasing hemoglobin levels and oxygen saturation in the blood in third trimester pregnant women.&lt;/p&gt;&lt;p&gt; &lt;/p&gt;&lt;p&gt; &lt;/p&gt;

Efficacy of Rectal Misoprostol in Active Management of Third Stage of Labour in Comparison with Oxytocin

Background Third stage of labour is defined as the time from delivery the baby to complete delivery of the placenta and its attached membranes Most common complications of the third stage of labour are postpartum hemorrhage (PPH). Active management of third stage of labour (AMTL) prevents PPH. Misoprostol is a prostaglandin E1 analogue has been suggested as an alternative of the routine prophylactic oxytocic agents in AMTL. Rectal route had been chosen because it avoids gastrointestinal side effects Objectives: To asses effectiveness of (400 mcg) rectally administered misoprostol tablet in the AMTL in comparison with standard oxytocin regimen Patients and Methods In prospective case-control study, 100 women were randomized, 50 patients received either 400mcg misoprostol tablets rectally (study medication) the other 50 received 10 IU oxytocin in 500 ml Ringer lactate solution IV. As a method of AMTL. Patient with risk factor for PPH had been excluded. A comparison between the two groups in their amount of blood loss, drop in hemoglobin level from admission to 24 hr. after delivery, duration of third stage of labour and any side effects appear done Results Maximum amount of blood loss in both groups of the study was 440 ml, so we had no case of PPH. There was no stastically significant difference in mean blood loss, mean difference in Hb level (gm/dl) on admission and 24 hours after delivery, and duration of third stage of labour found between study groups [p values= 0.138, 0.227, 0.08 respectively]. More shivering occurs in cases but the difference was not significant. Conclusions: Misoprostol in a dose of 400 mcg rectally shows promising results, it seems safe and effective drug that can be used in the management of third stage of labour.