ABSTRACT Background: The strength of the binding between brackets and tooth surfaces has a major impact on how well orthodontic therapy works. The shear bond strength of orthodontic brackets may be strengthened by the invention of bonding agents supplemented with nanoparticles, thanks to recent developments in nanoparticle technology. Materials and Methods: In order to perform a randomized controlled experiment, 90 human premolars were excised for orthodontic purposes. Three groups of 30 teeth were randomly assigned to each group: Group A used a bonding agent augmented with nanoparticles of titanium dioxide (TiO2), Group B used nanoparticles of zirconium dioxide (ZrO2), and Group C used a standard bonding agent as a reference. The appropriate bonding chemicals were used to attach the brackets to the teeth, and a universal testing equipment was used to measure the shear bond strength. Stereomicroscopic analysis was used to evaluate the failure mechanisms. To do statistical analysis, Tukey’s post hoc test and analysis of variance were used. Results: There were significant differences (P < 0.05) in the mean shear bond strength values across the groups. The average shear bond strength for Group A (TiO2) was 18.5 ± 2.3 MPa, that for Group B (ZrO2) was 17.2 ± 2.6 MPa, and that for Group C (control) was 14.8 ± 2.4 MPa. In comparison to Groups B and C, Group A exhibited a statistically greater bond strength, although Group B also showed an improvement over the control. According to the failure mode analysis, the control group had mostly adhesive failures, whereas the nanoparticle groups saw mixed failures. Conclusion: When TiO2 and ZrO2 nanoparticles are added to bonding agents, the shear bond strength of orthodontic brackets is greatly increased in comparison to traditional bonding agents. TiO2-reinforced materials performed better, pointing to possible benefits for orthodontic applications. It is advised that further study be done to examine the long-term impacts and therapeutic implications of these results.
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