Descriptive Naming Research Articles

NIMG-63. GAMMA-BAND MODULATIONS OF ELECTROCORTICOGRAM (ECOG) INDUCED BY COGNITIVE-LINGUISTIC TASKS DURING AWAKE CRANIOTOMY FOR FEASIBLE FUNCTIONAL LANGUAGE MAPPING

Abstract INTRODUCTION Intraoperative functional language mapping has uncertainty in predicting language function and post-surgical outcomes. We study the feasibility of functional mapping using electrocorticogram (ECoG) gamma-band modulations induced by linguistic tasks having different complexity levels. METHODS Five subjects with left temporal lobe glioma underwent resection involving awake language mapping using a 4x8 ECoG electrode grid. A MATLAB/Simulink based real-time software system was used to map task-induced gamma-band modulations as 2D heat maps. Tasks included verbally responding to single word/tone categorization; object, action, written descriptive and auditory naming respectively. Auditory stimuli were provided during word/tone categorization (duration 300~500ms) and auditory naming tasks ( > 1s). Other tasks provided visual stimuli (line drawings or written phrases). Bipolar DCS (2~6 mA, 60Hz, 2s) was applied at different electrode pairs while repeating the naming tasks. RESULTS Cortical regions activated by word stimuli and the auditory naming task were similar; superior, middle temporal gyri (STG, MTG). Visual naming tasks modulated posterior MTG (pMTG) and STG (written naming). Reproducible speech arrests occurred during different naming tasks while stimulating specific electrode pairs, even though not all electrodes had strong task-specific activations. Considerable inter-personal variability of language areas identified with DCS was observed, despite the similarity of task-specific gamma-band modulated regions across subjects. Post-operative decline in language score was observed in one subject, with resection boundary covering gamma modulated regions during auditory processing tasks but no DCS identified region. CONCLUSION Intraoperative language mapping guided by gamma-band ECoG modulations induced by simple word/tone categorization task exhibited similar patterns to more complex naming tasks, suggesting this task may be a viable approach to localize functional cortex, especially in patients unable to reliably perform more difficult paradigms. Utilizing this method in conjunction with DCS mapping guided by visual naming tasks, eloquent cortical language areas may be better preserved reducing post-operative language deficits.

A uniqueness-based approach to provide descriptive JUnit test names

The descriptive naming of unit tests has always been a focal task in test maintenance. Previous work tried to use different methods to generate descriptive names for unit tests or provide suggestions to improve existing names, but they often neglected developers’ needs. Therefore, they are unlikely to be useful to provide descriptive test names for developers in real world. Based on a recent study that can identify uniqueness of JUnit tests, we propose a uniqueness-based name generation approach to generate descriptive test names that meet developers’ needs. Comparing with several alternative approaches, the generated name from our approach are preferred by professional developers, or at least at the same level of preference as the original test names.

Intra– and inter–hemispheric network dynamics supporting object recognition and speech production

We built normative brain atlases that animate millisecond-scale intra- and inter-hemispheric white matter-level connectivity dynamics supporting object recognition and speech production. We quantified electrocorticographic modulations during three naming tasks using event-related high-gamma activity from 1,114 nonepileptogenic intracranial electrodes (i.e., non-lesional areas unaffected by epileptiform discharges). Using this electrocorticography data, we visualized functional connectivity modulations defined as significant naming-related high-gamma modulations occurring simultaneously at two sites connected by direct white matter streamlines on diffusion-weighted imaging tractography. Immediately after stimulus onset, intra- and inter-hemispheric functional connectivity enhancements were confined mainly across modality-specific perceptual regions. During response preparation, left intra-hemispheric connectivity enhancements propagated in a posterior-to-anterior direction, involving the left precentral and prefrontal areas. After overt response onset, inter- and intra-hemispheric connectivity enhancements mainly encompassed precentral, postcentral, and superior-temporal (STG) gyri. We found task-specific connectivity enhancements during response preparation as follows. Picture naming enhanced activity along the left arcuate fasciculus between the inferior-temporal and precentral/posterior inferior-frontal (pIFG) gyri. Nonspeech environmental sound naming augmented functional connectivity via the left inferior longitudinal and fronto-occipital fasciculi between the medial-occipital and STG/pIFG. Auditory descriptive naming task enhanced usage of the left frontal U-fibers, involving the middle-frontal gyrus. Taken together, the commonly observed network enhancements include inter-hemispheric connectivity optimizing perceptual processing exerted in each hemisphere, left intra-hemispheric connectivity supporting semantic and lexical processing, and inter-hemispheric connectivity for symmetric oral movements during overt speech. Our atlases improve the currently available models of object recognition and speech production by adding neural dynamics via direct intra- and inter-hemispheric white matter tracts.

NIMG-64. INTRAOPERATIVE LANGUAGE MAPPING USING GAMMA-BAND MODULATIONS OF ELECTROCORTICOGRAM (ECOG) INDUCED BY WORD/SOUND CATEGORIZATION TASK: VALIDATION WITH REPRODUCIBLE SPEECH ARRESTS DURING LINGUISTIC TASKS

Abstract OBJECTIVE Determination of the correlation between gamma-band modulations of electrocorticogram (ECoG) induced by linguistic tasks and reproducible speech arrests caused by bipolar direct cortical stimulations (DCS). METHODS 3 subjects (age 39, 56, 64 years) with left temporal lobe glioma underwent surgery involving awake craniotomy. A 4x8 ECoG electrode grid (2.3mm contact exposure, 1cm contact spacing) was placed above the respective tumor area. A MATLAB-Simulink based real-time software system running on a portable laptop computer was used to map gamma-band modulations as a 2D heat map while the subjects engaged in different linguistic tasks: word/sound categorization by pressing a button, object naming, action naming, written descriptive naming, and auditory descriptive naming. Auditory stimulus was applied during word/sound categorization task (duration 300 – 500ms), auditory descriptive naming ( > 1s); other tasks involved visual stimulus only. The subjects repeated the four naming tasks while bipolar DCS (2/4/6 mA, 60Hz, 2s) was applied at different electrode pairs. RESULTS The electrodes having stronger gamma-band modulations were distinct for different tasks. Reproducible speech arrests occurred during object, action, auditory naming tasks while stimulating specific electrode pairs, even though not all these electrodes had strong activations during these tasks. Across all subjects these electrodes had strong activations consistently during word/sound categorization tasks, starting as early as 250ms and lasting even after the auditory stimuli were terminated (~ 650ms). The longer activations can be associated with word recognition process. The subjects self-reported about having difficulty in comprehension rather than speech production during speech arrests. 3D brain rendering using MRI images showed that the speech arrest electrodes were identically located on the superior temporal gyrus, inferior to central sulcus for all 3 subjects. CONCLUSION Intraoperative language mapping guided by gamma-band ECoG modulations induced by word/sound categorization tasks can be utilized to localize eloquent cortex associated with auditory processing.

NCOG-14. INTRAOPERATIVE COGNITIVE-LINGUISTIC MAPPING GUIDED BY VISUALIZATION OF GAMMA BAND MODULATION ELECTROCORTICOGRAMS: PROOF OF CONCEPT IN A PATIENT WITH LEFT TEMPORAL AND OCCIPITAL LOW-GRADE ASTROCYTOMA

Abstract OBJECTIVE Determine the feasibility and preliminary utility of a novel approach to intraoperative brain mapping guided by visualization of electrocorticography (ECoG) heat maps. METHODS A 39-year-old male with a biopsy-proven left posterior temporal and occipital WHO grade II IDH-mutant astrocytoma underwent awake craniotomy with intraoperative language mapping. Language mapping utilized a dual iPad stimulus presentation system (NeuroMapper) coupled to a portable real-time neural signal processing system capable of both recording cortical activity and delivering direct cortical stimulation in a closed-loop fashion. An ECoG grid (4x8 with 1cm pitch) which covered the majority of the left temporal lobe was used to assess oscillatory cortical activity during administration of language paradigms including object, action, auditory descriptive, and written descriptive naming. ECoG recording and cortical stimulation were synchronized with stimulus presentation via a photosensor attached to the patient-facing tablet. Gamma band modulations in response to language paradigms at each electrode were processed in real-time and visualized as heat maps in MATLAB/Simulink. Following recording and visualization, bipolar direct cortical stimulation from the grid was conducted for each neighboring electrode pair (up to an intensity of 6 mA) during administration of language tasks. RESULTS Despite mild fluent aphasia, a large set of reliable baseline stimuli were obtained for the language mapping paradigms. All naming paradigms resulted in strongest heat map activation at electrode 12 located in the anterior to mid superior temporal gyrus. During stimulation, consistent speech arrest was observed across all paradigms when stimulating electrode pair 11-12, indicating good correspondence with ECoG heat map recordings. Additionally, this region corresponded well with posterior language network representation via resting-state fMRI. CONCLUSION Intraoperative real-time visualization of task-based ECoG gamma band modulation is feasible and may help identify targets for direct cortical stimulation. If validated, this may improve the efficiency and accuracy of intraoperative language mapping.

Descriptive Naming & Summarization of large text using Topic Model-A Survey

Due to the plethora of documents containing large scale of text that are available on web it sometimes gets difficult to go through each document to get the clear picture of what the text is depicting. In this paper, we are analyzing several techniques to evaluate Topic Model. A Topic Model is a very popular approach for representing and smoothing the content of documents. Here we will focus on uncovering the thematic structure of a corpus of document that will help in document classification and for compact document topic representation. We have gone through some of the famous topic model such as-Latent Semantic Indexing (LSI),Probabilistic Latent Semantic Indexing (PLSI),Latent Dirichlet Allocation (LDA),Pachinko Allocation Model (PAM) where we encounter few issues such as Topic models are not proper for some SNS such as micro blogging and supervise learning techniques are designed for one-labeled corpus-i. e. they are limiting the document to a single label.

Polysemy Revisited

Abstract This paper addresses the cognitive models that frame our understanding of what is traditionally called “metaphoric polysemy”, a well-established principle at work when it comes to naming the animals around us. In particular, taking the Roman nomenclature of aquatic animals as a case study, polysemy is redefined according to some basic cognitive principles of ethnobiological classification such as analogical similarity, biological essentialism and the role of simultaneous metaphoric and metonymic associations to the perceptual/cultural constraints targeted on the biological referent for naming it – the result is at least two kinds of metaphoric polysemy, to be called “external” (or exo-polysemy) and “internal” (or endo-polysemy), respectively. The idea is that the naming patterns that emerge from the ethnozoological nomenclature under examination may not only provide a better understanding of an ancient people’s zooanthropology but a paradigm for analysing descriptive ethnobiological naming in general.

Single left coronary ostium and an anomalous prepulmonic right coronary artery in 2 dogs with congenital pulmonary valve stenosis

A coronary artery anomaly characterized by the presence of a single left coronary ostium with absence of the right coronary ostium and an anomalous prepulmonic right coronary artery course was observed in two dogs with concurrent congenital pulmonary valve stenosis. This unique coronary artery anatomy is similar to the previously described single right coronary ostium with anomalous prepulmonic left coronary artery, the so-called type R2A anomaly, in that an anomalous coronary artery encircles the pulmonary valve annulus. Both dogs of this report, a boxer and an English bulldog, were of breeds known to be at risk for the type R2A anomaly. As such, veterinarians should be aware that the echocardiographic presence of a left coronary ostium in a dog with pulmonary valve stenosis does not exclude the possibility of a prepulmonic coronary artery anomaly that may enhance the risk of complications during balloon pulmonary valvuloplasty. A descriptive naming convention for coronary artery anomalies in dogs is also presented, which may be preferable to the older coding classification scheme.

Electrocorticographic functional mapping identifies human cortex critical for auditory and visual naming

More comprehensive, and efficient, mapping strategies are needed to avoid post-operative language impairments in patients undergoing epilepsy surgery. Conservative resection of dominant anterior frontal or temporal cortex frequently results in post-operative naming deficits despite standard pre-operative electrocortical stimulation mapping of visual object (picture) naming. Naming to auditory description may better simulate word retrieval in human conversation but is not typically tested, in part due to the time demands of electrocortical stimulation mapping. Electrocorticographic high gamma (60-150 Hz) activity, recorded simultaneously through the same electrodes used for stimulation mapping, has recently been used to map brain function more efficiently, and has at times predicted deficits not anticipated based on stimulation mapping alone. The present study investigated electrocorticographic mapping of visual object naming and auditory descriptive naming within conservative dominant temporal or frontal lobe resection boundaries in 16 patients with 933 subdural electrodes implanted for epilepsy surgery planning. A logistic regression model showed that electrodes within traditional conservative dominant frontal or temporal lobe resection boundaries were significantly more likely to record high gamma activity during auditory descriptive naming than during visual object naming. Eleven patients ultimately underwent resection and 7 demonstrated post-operative language deficits not anticipated based on electrocortical stimulation mapping alone. Four patients with post-operative deficits underwent a resection that included sites where high gamma activity was observed during naming. These findings indicate that electrocorticographic mapping of auditory descriptive naming may reduce the risk of permanent post-operative language deficits following dominant temporal or frontal resection.

Memories of Cas Jeekel, friend, colleague, and role model

Memories of Cas Jeekel, friend, colleague, and role model

SENS: A Scalable and Expressive Naming System for Resource Information Retrieval

SUMMARY We have designed a scalable and expressive naming system called SENS, capable of retrieving information of computing and content resources distributed widely across the Internet through exact queries and multi-attribute range queries over resource names. Our system utilizes a descriptive naming scheme to name resources and a multi-dimensional resource ID space for message routing through an overlay network of name servers (NSs). The resource ID space is constructed on the overlay network based on CAN routing algorithm. Our novel mapping scheme between resource names and resource IDs preserves resource ID locality while still achieving good load balancing regarding resource information distribution. We also propose a multicast routing algorithm to deliver resource information and a broadcast routing algorithm to route query messages to corresponding NSs with small cost of message transmission. Our simulation results show that our system can achieve good routing performance and

Normative data on 372 stimuli for descriptive naming

Naming problems are common in patients with dominant temporal lobe epilepsy (TLE) and anterior temporal lobectomy (ATL). Descriptive naming may be an especially useful procedure for the presurgical workup of candidates for ATL, given its sensitivity for detecting subtle naming problems in TLE and its localization to anterior temporal regions that are commonly targeted for resection in ATL. This study provides normative data pertaining to difficulty level (accuracy and reaction time) on 372 descriptive naming items in four conceptual categories: common non-living, common living, unique non-living, and unique living things. These data will be useful to investigators who wish to develop protocols for clinical assessment or stimuli for functional imaging paradigms aimed at assessing the function of the anterior temporal lobes.

Le Cluny, le Champollion : d'un emploi non prototypique de nom propre modifié

Beside the French pattern Le Hugo de 1870, la Bretagne des années 30, another naming structure which has not been studied yet can be found: it combines a syntactical modifying process and a semantic feature in a new type of proper name allowing a speaker to refer to individuals such as a restaurant (le Cluny), a theater (le Champollion), a litterature prize (le Goncourt)… Through a morphosyntactical analysis, one first naming pattern can be isolated; this pattern is characterized by a speaker’s choice between a type LE N Npr (le prix Goncourt) and a shorter one, LE Npr (le Goncourt). Another type can be found where the actual naming form is the shorter one: Le Cluny vs ?le restaurant Cluny; le Champollion vs ?le cinéma Champollion. Then we assume that the definite article can be interpreted in a naming theory model where a proper name like Cluny in Le Cluny is no longer a true proper name but a special sort of uniquely qualifying predicate. We finally show that the choice between LE N Npr and LE Npr is based upon a sort of pragmatic regulation we call a descriptive naming (signalétique de nomination) which can be exemplified in the same way, but in the field of class naming, by modified trade names like un Renault, un Bic.

Le Cluny, le Champollion : d'un emploi non prototypique de nom propre modifié

Beside the French pattern Le Hugo de 1870, la Bretagne des années 30, another naming structure which has not been studied yet can be found: it combines a syntactical modifying process and a semantic feature in a new type of proper name allowing a speaker to refer to individuals such as a restaurant (le Cluny), a theater (le Champollion), a litterature prize (le Goncourt)… Through a morphosyntactical analysis, one first naming pattern can be isolated; this pattern is characterized by a speaker’s choice between a type LE N Npr (le prix Goncourt) and a shorter one, LE Npr (le Goncourt). Another type can be found where the actual naming form is the shorter one: Le Cluny vs ?le restaurant Cluny; le Champollion vs ?le cinéma Champollion. Then we assume that the definite article can be interpreted in a naming theory model where a proper name like Cluny in Le Cluny is no longer a true proper name but a special sort of uniquely qualifying predicate. We finally show that the choice between LE N Npr and LE Npr is based upon a sort of pragmatic regulation we call a descriptive naming (signalétique de nomination) which can be exemplified in the same way, but in the field of class naming, by modified trade names like un Renault, un Bic.

Nomenclator descriptive query optimization for large X.500 environments

Nomenclator is an architecture for providing efficient descriptive (attribute-based) naming in a large internet environment. As a test of the basic design, we have built a Nomenclator prototype that uses X.500 as its underlying data repository. X.500 SEARCH queries that previously took several minutes, can, in many cases, be answered in a matter of seconds. Our system improves descriptive query performance by trimming branches of the X.500 directory tree from the search. These tree-trimming techniques are part of an active catalog that constrains the search space as needed during query processing. The active catalog provides information about the data distribution (meta-data) to constrain query processing on demand. Nomenclator caches both data (responses to queries) and meta-data (data distribution information, tree-trimming techniques, data access techniques) to speed future queries. Nomenclator relieves users of the need to understand the structure of the name space to locate objects quickly in a large, structured name environment. Nomenclator is a meta-level service that will eventually incorporate other name services in addition to X.500. Its techniques for improving performance should be generally applicable to other naming systems. hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh Research supported in part by an AT&T Ph.D. Scholarship, National Science Foundation grants CCR8703373 and CCR-8815928, Office of Naval Research grant N00014-89-J-1222, and a Digital Equipment Corporation External Research Grant.